MA27745A1 - Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci. - Google Patents
Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci.Info
- Publication number
- MA27745A1 MA27745A1 MA28485A MA28485A MA27745A1 MA 27745 A1 MA27745 A1 MA 27745A1 MA 28485 A MA28485 A MA 28485A MA 28485 A MA28485 A MA 28485A MA 27745 A1 MA27745 A1 MA 27745A1
- Authority
- MA
- Morocco
- Prior art keywords
- benzoylureidopyridyl
- piperidine
- substituted
- acid derivatives
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- NMDAFFPZWCMMLW-UHFFFAOYSA-N n-[(1-pyridin-2-ylpiperidin-2-yl)carbamoyl]benzamide Chemical class C=1C=CC=CC=1C(=O)NC(=O)NC1CCCCN1C1=CC=CC=N1 NMDAFFPZWCMMLW-UHFFFAOYSA-N 0.000 title abstract 2
- NYCVCXMSZNOGDH-UHFFFAOYSA-N pyrrolidine-1-carboxylic acid Chemical class OC(=O)N1CCCC1 NYCVCXMSZNOGDH-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention se rapporte à des composés de formule (I) dans laquelle les groupes ont la signification indiquée dans la description, ainsi qu'à leurs sels physiologiquement acceptables. Ces composés peuvent par exemple servir de médicaments pour prévenir et traiter un diabète de type 2.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10309929A DE10309929B4 (de) | 2003-03-07 | 2003-03-07 | Substituierte Benzoylureidopyridyl-piperidin- und -pyrrolidin-carbonsäurederivate, Verfahren zu deren Herstellung und deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA27745A1 true MA27745A1 (fr) | 2006-02-01 |
Family
ID=32945839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28485A MA27745A1 (fr) | 2003-03-07 | 2005-09-07 | Derives d'acide benzoylureidopyridyl-piperidine et pyrrolidinecarboxylique substitues, methode de production de ceux-ci et utilisation de ceux-ci. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1603895B1 (fr) |
| JP (1) | JP2006519795A (fr) |
| KR (1) | KR20050108487A (fr) |
| CN (1) | CN1759109A (fr) |
| AT (1) | ATE386735T1 (fr) |
| AU (1) | AU2004218267A1 (fr) |
| BR (1) | BRPI0408148A (fr) |
| CA (1) | CA2518322A1 (fr) |
| CO (1) | CO5690587A2 (fr) |
| DE (2) | DE10309929B4 (fr) |
| HR (1) | HRP20050779A2 (fr) |
| MA (1) | MA27745A1 (fr) |
| MX (1) | MXPA05009122A (fr) |
| NO (1) | NO20054418L (fr) |
| PL (1) | PL377293A1 (fr) |
| RU (1) | RU2005131011A (fr) |
| WO (1) | WO2004078743A1 (fr) |
| ZA (1) | ZA200506119B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7223786B2 (en) | 2004-11-15 | 2007-05-29 | Bristol-Myers Squibb Company | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors |
| WO2006055463A2 (fr) | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | Derives de 2-amino-3-tetraline fonctionnalisee et inhibiteurs de la glycogene phosphorylase associes |
| US7226942B2 (en) | 2004-11-15 | 2007-06-05 | Bristol-Myers Squibb Company | 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| WO2006053274A2 (fr) | 2004-11-15 | 2006-05-18 | Bristol-Myers Squibb Company | Derives de tetraline 2-amino-1-fonctionnalises et inhibiteurs correspondants de glycogene phosphorylase |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| RU2012118504A (ru) * | 2009-10-06 | 2013-11-20 | Бристол-Маерс Сквибб Компани | Пирролидиновые модуляторы gpr40 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3034004A1 (de) * | 1980-09-10 | 1982-04-22 | Hoechst Ag, 6000 Frankfurt | Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung |
| DE10116768A1 (de) * | 2001-04-04 | 2002-10-10 | Aventis Pharma Gmbh | Acylphenylharnstoffderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| TR200401029T4 (tr) * | 2000-06-09 | 2004-06-21 | Aventis Pharma Deutschland Gmbh | Asilfenil-üre türevleri, imalat yöntemleri ve ilaç maddesi olarak kullanımları |
| DE10125567B4 (de) * | 2001-05-25 | 2004-08-26 | Aventis Pharma Deutschland Gmbh | Carbonamid substituierte Phenylharnstoffderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| PE20021091A1 (es) * | 2001-05-25 | 2003-02-04 | Aventis Pharma Gmbh | Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion |
| IL164249A0 (en) * | 2002-04-11 | 2005-12-18 | Aventis Pharma Gmbh | Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use |
| DE50311923D1 (de) * | 2002-07-11 | 2009-10-29 | Sanofi Aventis Deutschland | Harnstoff- und urethan-substituierte acylharnstoffe, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| HRP20050022A2 (en) * | 2002-07-12 | 2006-03-31 | Sanofi-Aventis Deutschland Gmbh | Heterocyclically substituted benzoylureas, method for their production and their use as medicaments |
-
2003
- 2003-03-07 DE DE10309929A patent/DE10309929B4/de not_active Expired - Fee Related
-
2004
- 2004-02-21 WO PCT/EP2004/001735 patent/WO2004078743A1/fr not_active Ceased
- 2004-02-21 EP EP04713467A patent/EP1603895B1/fr not_active Expired - Lifetime
- 2004-02-21 RU RU2005131011/04A patent/RU2005131011A/ru not_active Application Discontinuation
- 2004-02-21 AT AT04713467T patent/ATE386735T1/de not_active IP Right Cessation
- 2004-02-21 HR HR20050779A patent/HRP20050779A2/xx not_active Application Discontinuation
- 2004-02-21 MX MXPA05009122A patent/MXPA05009122A/es unknown
- 2004-02-21 JP JP2006504448A patent/JP2006519795A/ja not_active Ceased
- 2004-02-21 CA CA002518322A patent/CA2518322A1/fr not_active Abandoned
- 2004-02-21 AU AU2004218267A patent/AU2004218267A1/en not_active Abandoned
- 2004-02-21 KR KR1020057016583A patent/KR20050108487A/ko not_active Withdrawn
- 2004-02-21 CN CNA2004800062407A patent/CN1759109A/zh active Pending
- 2004-02-21 PL PL377293A patent/PL377293A1/pl not_active Application Discontinuation
- 2004-02-21 BR BRPI0408148-0A patent/BRPI0408148A/pt not_active IP Right Cessation
- 2004-02-21 DE DE502004006253T patent/DE502004006253D1/de not_active Expired - Lifetime
-
2005
- 2005-08-01 ZA ZA200506119A patent/ZA200506119B/en unknown
- 2005-09-06 CO CO05089471A patent/CO5690587A2/es not_active Application Discontinuation
- 2005-09-07 MA MA28485A patent/MA27745A1/fr unknown
- 2005-09-23 NO NO20054418A patent/NO20054418L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20050779A2 (en) | 2006-10-31 |
| EP1603895A1 (fr) | 2005-12-14 |
| DE502004006253D1 (de) | 2008-04-03 |
| MXPA05009122A (es) | 2005-10-20 |
| ZA200506119B (en) | 2006-11-29 |
| JP2006519795A (ja) | 2006-08-31 |
| WO2004078743A1 (fr) | 2004-09-16 |
| ATE386735T1 (de) | 2008-03-15 |
| EP1603895B1 (fr) | 2008-02-20 |
| KR20050108487A (ko) | 2005-11-16 |
| NO20054418L (no) | 2005-09-23 |
| DE10309929B4 (de) | 2006-02-23 |
| DE10309929A1 (de) | 2004-12-02 |
| BRPI0408148A (pt) | 2006-03-01 |
| CO5690587A2 (es) | 2006-10-31 |
| PL377293A1 (pl) | 2006-01-23 |
| RU2005131011A (ru) | 2006-05-10 |
| CN1759109A (zh) | 2006-04-12 |
| AU2004218267A1 (en) | 2004-09-16 |
| CA2518322A1 (fr) | 2004-09-16 |
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