[go: up one dir, main page]

MA26057A1 - Appareil et procédé de perçage de peau par microdents - Google Patents

Appareil et procédé de perçage de peau par microdents

Info

Publication number
MA26057A1
MA26057A1 MA27151A MA27151A MA26057A1 MA 26057 A1 MA26057 A1 MA 26057A1 MA 27151 A MA27151 A MA 27151A MA 27151 A MA27151 A MA 27151A MA 26057 A1 MA26057 A1 MA 26057A1
Authority
MA
Morocco
Prior art keywords
impact
microprotrusion member
stratum corneum
skin
microdents
Prior art date
Application number
MA27151A
Other languages
English (en)
Inventor
Michel J N Cormier
Peter E Daddona
Richard L Keenan
Weiqi Lin
James A Matriano
Ahmad P Samiee
Joseph C Trautman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22906027&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA26057(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of MA26057A1 publication Critical patent/MA26057A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
    • A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150801—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming
    • A61B5/150824—Means for facilitating use, e.g. by people with impaired vision; means for indicating when used correctly or incorrectly; means for alarming by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150977—Arrays of piercing elements for simultaneous piercing
    • A61B5/150984—Microneedles or microblades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15103—Piercing procedure
    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15113—Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15142—Devices intended for single use, i.e. disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/151—Devices specially adapted for taking samples of capillary blood, e.g. by lancets, needles or blades
    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
    • A61B5/15188—Constructional features of reusable driving devices
    • A61B5/1519—Constructional features of reusable driving devices comprising driving means, e.g. a spring, for propelling the piercing unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00743—Type of operation; Specification of treatment sites
    • A61B2017/00747—Dermatology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Manufacturing & Machinery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
  • Perforating, Stamping-Out Or Severing By Means Other Than Cutting (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Massaging Devices (AREA)
MA27151A 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents MA26057A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24030700P 2000-10-13 2000-10-13

Publications (1)

Publication Number Publication Date
MA26057A1 true MA26057A1 (fr) 2004-04-01

Family

ID=22906027

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27151A MA26057A1 (fr) 2000-10-13 2003-05-12 Appareil et procédé de perçage de peau par microdents

Country Status (22)

Country Link
US (2) US7131960B2 (fr)
EP (1) EP1341453B1 (fr)
JP (1) JP4659332B2 (fr)
KR (1) KR20030068136A (fr)
CN (1) CN1250171C (fr)
AT (1) ATE428357T1 (fr)
AU (2) AU9682801A (fr)
BR (1) BR0114629A (fr)
CA (1) CA2425315C (fr)
CZ (1) CZ20031037A3 (fr)
DE (1) DE60138411D1 (fr)
ES (1) ES2324461T3 (fr)
HU (1) HUP0303558A2 (fr)
IL (1) IL155374A0 (fr)
MA (1) MA26057A1 (fr)
MX (1) MXPA03003299A (fr)
NO (1) NO20031681L (fr)
NZ (1) NZ525294A (fr)
PL (1) PL360998A1 (fr)
RU (1) RU2275871C2 (fr)
WO (1) WO2002030301A1 (fr)
ZA (1) ZA200303633B (fr)

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69719761T2 (de) * 1996-06-18 2003-12-18 Alza Corp., Palo Alto Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
US6918901B1 (en) * 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
KR20030068136A (ko) * 2000-10-13 2003-08-19 알자 코포레이션 미세 돌기부로 피부를 천공하기 위한 장치 및 방법
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
MXPA03003303A (es) * 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
WO2002094368A1 (fr) * 2000-10-26 2002-11-28 Alza Corporation Dispositifs d'administration de medicament transdermique avec des microprotrusions enrobees
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
ATE444773T1 (de) * 2001-04-20 2009-10-15 Alza Corp Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält
EP1485317A2 (fr) * 2001-11-30 2004-12-15 Alza Corporation Procedes et appareils de formation de grilles de microprojections
RU2314760C2 (ru) * 2001-12-20 2008-01-20 Алза Корпорейшн Микровыступы, пробивающие кожу, имеющие средство регулирования глубины пробивки
US6912417B1 (en) 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
KR20050054483A (ko) * 2002-06-28 2005-06-10 알자 코포레이션 코팅된 미세돌출부를 갖는 경피용 약물 전달 장치
KR101323980B1 (ko) * 2002-07-19 2013-10-30 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 니들 장치, 마이크로 니들 장치를 사용하는 방법 및 마이크로 니들 장치를 송출하는 방법
WO2004030743A2 (fr) * 2002-09-30 2004-04-15 Alza Corporation Methode et dispositif d'administration de medicaments presentant des microprojections revetues comprenant des vasoconstricteurs
WO2004044557A2 (fr) * 2002-11-12 2004-05-27 Argose, Inc. Mesure non invasive d'analytes
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AR042815A1 (es) * 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
US7226457B2 (en) * 2003-02-19 2007-06-05 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Epidermal sampling apparatus and method
US7087063B2 (en) * 2003-02-19 2006-08-08 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Abrasion device and method
CA2530531A1 (fr) * 2003-06-30 2005-01-20 Alza Corporation Formulations pour microprojections revetues contenant des contre-ions non volatils
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
TW200513280A (en) * 2003-07-02 2005-04-16 Alza Corp Microprojection array immunization patch and method
JP2007501071A (ja) * 2003-08-04 2007-01-25 アルザ・コーポレーシヨン 経皮作用剤流率を向上させる方法および装置
WO2005042054A2 (fr) 2003-10-24 2005-05-12 Alza Corporation Procede et systeme de pretraitement permettant d'ameliorer l'administration transdermique de medicaments
JP2007508914A (ja) * 2003-10-24 2007-04-12 アルザ・コーポレーシヨン 経皮薬剤送達を促進するための装置及び方法
KR20060120156A (ko) * 2003-10-28 2006-11-24 알자 코포레이션 담배의 이용빈도를 감소시키기 위한 방법 및 장치
EP1677687A4 (fr) * 2003-10-28 2008-09-17 Alza Corp Administration de conjugues polymeres de peptides et de proteines therapeutiques par le biais de microprotuberances revetues
WO2005044333A2 (fr) * 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
US8029765B2 (en) * 2003-12-24 2011-10-04 Masimo Laboratories, Inc. SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors
CA2552385C (fr) * 2003-12-29 2013-07-23 3M Innovative Properties Company Dispositifs medicaux et kits comprenant ces dispositifs
CN1636505B (zh) * 2004-01-09 2011-11-09 希森美康株式会社 提取器具、提取装置和血糖值测量装置
JP5221127B2 (ja) * 2004-03-08 2013-06-26 アイコアー メディカル システムズ、インク． 電気を利用した治療剤移送のための改良された装置
WO2005094526A2 (fr) 2004-03-24 2005-10-13 Corium International, Inc. Dispositif d'administration transdermique
JP2007537783A (ja) * 2004-04-13 2007-12-27 アルザ コーポレイション 複数のワクチンを経皮送達するための装置及び方法
JP5007427B2 (ja) 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法
US20060030811A1 (en) * 2004-08-03 2006-02-09 Wong Patrick S Method and device for enhancing transdermal agent flux
WO2006029279A1 (fr) * 2004-09-08 2006-03-16 Alza Corporation Reseau de protuberances microscopiques possedant une adherence a la peau et une conformite ameliorees
DE602005027397D1 (de) 2004-11-18 2011-05-19 3M Innovative Properties Co Mikronadelanordungsapplikator und halter
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
TW200738252A (en) * 2005-02-16 2007-10-16 Alza Corp Apparatus and method for transdermal delivery of Epoetin-based agents
US8280476B2 (en) 2005-03-29 2012-10-02 Arkal Medical, Inc. Devices, systems, methods and tools for continuous glucose monitoring
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
AU2006252377A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
WO2007002523A2 (fr) * 2005-06-24 2007-01-04 3M Innovative Properties Company Timbre repliable et son procede d'application
JP5144510B2 (ja) 2005-06-27 2013-02-13 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイ適用装置
US20070078414A1 (en) * 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
CA2619452A1 (fr) * 2005-09-12 2007-03-22 Alza Corporation Dispositif d'administration transdermique enduisable a microprojections
EP1957145A4 (fr) * 2005-11-30 2011-03-23 3M Innovative Properties Co Reseaux de microaiguilles et leurs methodes d'utilisation
JP4963849B2 (ja) 2006-03-13 2012-06-27 シスメックス株式会社 微細孔形成システム
JP2009530307A (ja) * 2006-03-15 2009-08-27 アルザ コーポレイション 骨減少症を予防し、または治療するための副甲状腺ホルモン薬の経皮送達のための装置、並びに方法
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070299388A1 (en) * 2006-04-25 2007-12-27 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US20080058726A1 (en) * 2006-08-30 2008-03-06 Arvind Jina Methods and Apparatus Incorporating a Surface Penetration Device
WO2008091602A2 (fr) 2007-01-22 2008-07-31 Corium International, Inc. Applicateurs pour micro-aiguilles
AU2008241470B2 (en) 2007-04-16 2013-11-07 Corium Pharma Solutions, Inc. Solvent-cast microneedle arrays containing active
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
JP5508272B2 (ja) * 2007-10-29 2014-05-28 トランスファーマ メディカル リミテッド 垂直的なパッチ乾燥
US20090264911A1 (en) * 2008-04-16 2009-10-22 Kim Stanley I Single-use disposable lancing apparatus and methods
KR20160150109A (ko) * 2008-11-18 2016-12-28 쓰리엠 이노베이티브 프로퍼티즈 컴파니 중공 마이크로니들 어레이
WO2012018486A2 (fr) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Distribution et/ou réception rapide de fluides
EP2408372B1 (fr) 2009-03-02 2019-01-09 Seventh Sense Biosystems, Inc. Dispositifs associés au prélèvement de sang
BR112012001685B8 (pt) 2009-07-31 2021-06-22 3M Innovative Properties Co conjuntos de microagulhas ocas
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
ES2636673T3 (es) * 2010-04-28 2017-10-06 Kimberly-Clark Worldwide, Inc. Dispositivo para la administración de medicamentos contra la artritis reumatoide
EP2563451B1 (fr) * 2010-04-28 2017-11-01 Kimberly-Clark Worldwide, Inc. DISPOSITIFS MÉDICAUX POUR L'ADMINISTRATION D'ARNsi
GB201007207D0 (en) 2010-04-29 2010-06-16 Univ Cork Method
AU2011248108B2 (en) 2010-05-04 2016-05-26 Corium Pharma Solutions, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
CN105662530B (zh) 2010-05-04 2018-07-20 考里安国际公司 微针施加器
CN102917752A (zh) 2010-05-28 2013-02-06 久光制药株式会社 带微小突起的阵列
JP5597254B2 (ja) 2010-05-28 2014-10-01 久光製薬株式会社 微小突起付きアレイを有するデバイス
JP5562138B2 (ja) † 2010-06-24 2014-07-30 シスメックス株式会社 微細孔形成装置
EP2399635A1 (fr) 2010-06-28 2011-12-28 Sanofi-Aventis Deutschland GmbH Auto-injecteur
US8257379B2 (en) * 2010-07-29 2012-09-04 Kyphon Sarl Tissue structure perforation system and method
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
JP5885667B2 (ja) * 2010-10-07 2016-03-15 久光製薬株式会社 アプリケータ
EP2992827B1 (fr) 2010-11-09 2017-04-19 Seventh Sense Biosystems, Inc. Systèmes et interfaces pour prélèvement de sang
DE202010013095U1 (de) 2010-12-10 2011-02-17 Mt Derm Gmbh Vorrichtung zum wiederholten Aufstechen von Haut und Stechmodul
EP2489381A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489388A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489384A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489390A1 (fr) * 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489382A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489389A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Mécanisme d'encliquetage
EP2489385A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489380A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Dispositif d'injection
DK3363437T3 (da) 2011-02-18 2021-11-01 Endo Pharmaceuticals Inc Aminoindanforbindelser og anvendelse deraf i behandling af smerte
EP2489386A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
EP2489387A1 (fr) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injecteur
KR20120119250A (ko) * 2011-04-21 2012-10-31 (주)마이티시스템 단턱이 형성된 미세바늘
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
AU2012249683A1 (en) 2011-04-29 2013-11-14 Seventh Sense Biosystems, Inc. Devices and methods for collection and/or manipulation of blood spots or other bodily fluids
EP2701598A1 (fr) 2011-04-29 2014-03-05 Seventh Sense Biosystems, Inc. Systèmes et procédés pour collecter un fluide d'un sujet
AU2012249692A1 (en) 2011-04-29 2013-11-14 Seventh Sense Biosystems, Inc. Delivering and/or receiving fluids
USD687550S1 (en) * 2011-06-09 2013-08-06 3M Innovative Properties Company Handle for a micro-needle device
USD687551S1 (en) * 2011-06-09 2013-08-06 3M Innovative Properties Company Micro-needle applicator device
WO2013051568A1 (fr) * 2011-10-06 2013-04-11 久光製薬株式会社 Applicateur
WO2013055638A1 (fr) 2011-10-12 2013-04-18 3M Innovative Properties Company Système de pose d'un ensemble de micro-aiguilles intégrées
JP6495654B2 (ja) 2011-10-24 2019-04-03 アサナ バイオサイエンシズ，リミティド ライアビリティ カンパニー シクロヘキシルアミン類
USD733290S1 (en) 2012-01-27 2015-06-30 3M Innovative Properties Company Microneedle applicator
KR102064628B1 (ko) 2012-04-05 2020-01-08 히사미쓰 세이야꾸 가부시키가이샤 천자 장치 및 그 제조 방법
CN112933391A (zh) * 2012-05-01 2021-06-11 高等教育联邦系统-匹兹堡大学 用于经皮插入的尖端负载的微针阵列
JP6009302B2 (ja) * 2012-09-27 2016-10-19 シスメックス株式会社 微細孔形成装置、微細針チップおよびチップホルダ
CN105073102B (zh) 2012-10-01 2018-06-19 香港科技大学 透皮贴装置
USD725262S1 (en) 2012-11-16 2015-03-24 Ndm Technologies Limited Microneedle applicator
CA2896188C (fr) 2012-12-21 2021-02-23 Corium International, Inc. Micro-reseau pour la distribution d'un agent therapeutique et ses procedes d'utilisation
KR102158891B1 (ko) 2012-12-21 2020-09-22 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
ES2873202T3 (es) * 2013-01-08 2021-11-03 Kindeva Drug Delivery Lp Aplicador para aplicar un dispositivo de microagujas a la piel
ES2921481T3 (es) * 2013-03-12 2022-08-26 Corium Inc Aplicadores para microproyecciones
US10195409B2 (en) 2013-03-15 2019-02-05 Corium International, Inc. Multiple impact microprojection applicators and methods of use
CA2903763C (fr) 2013-03-15 2021-11-16 Corium International, Inc. Micro-reseau ayant des microstructures sans polymere, procedes de fabrication et procedes d'utilisation
WO2014144973A1 (fr) 2013-03-15 2014-09-18 Corium International, Inc. Micro-réseau pour administrer un agent thérapeutique, procédés d'utilisation et procédés de fabrication
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
WO2015017561A1 (fr) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Applicateur extra-plat de tampon de micro-aiguilles
US10232158B2 (en) 2013-09-18 2019-03-19 Cosmed Pharmaceutical Co., Ltd. Microneedle patch application device and patch holder
US10086183B2 (en) 2013-11-05 2018-10-02 Hisamitsu Pharmaceutical Co., Inc. Applicator
KR20220112867A (ko) 2013-12-16 2022-08-11 에이비에스 디벨롭먼트 원 인코포레이티드 P2x3 및/또는 p2x2/3 화합물 및 방법
CN103654969B (zh) * 2013-12-24 2015-12-30 湖州美奇医疗器械有限公司 一种医疗助针器
EP3188714A1 (fr) 2014-09-04 2017-07-12 Corium International, Inc. Matrice de microstructures, procédé de production et procédés d'utilisation
US10137289B2 (en) * 2014-12-20 2018-11-27 Esthetic Education LLC Microneedle cartridge and nosecone assembly
WO2016149673A1 (fr) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Composés bioactifs conjugués à des substrats de réseaux de micro-aiguilles
MA41818A (fr) 2015-03-27 2018-01-30 Leo Pharma As Timbre à micro-aiguilles pour administration d'un principe actif à la peau
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017023404A (ja) * 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
EP3345648A4 (fr) 2015-09-02 2019-04-17 Hisamitsu Pharmaceutical Co., Inc. Applicateur
US9918932B2 (en) 2016-02-19 2018-03-20 Zosano Pharma Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
KR102377747B1 (ko) 2016-03-16 2022-03-23 코스메드 파마소티컬 씨오 쩜 엘티디 마이크로니들 패치 케이스
MY201757A (en) 2016-03-28 2024-03-15 Ichor Medical Systems Inc Method and apparatus for delivery of therapeutic agents
RU2019112740A (ru) 2016-09-30 2020-11-02 АСАНА БАЙОСАЙЕНСИЗ, ЭлЭлСи P2x3 и/или p2x2/3 соединения и способы
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
US11660264B2 (en) * 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
KR102340393B1 (ko) 2017-08-23 2021-12-17 조사노 파마 코포레이션 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법
MX2020003699A (es) 2017-10-17 2020-08-13 Kindeva Drug Delivery Lp Aplicador para aplicar una matriz de microagujas a la piel.
JP2019126733A (ja) 2018-01-24 2019-08-01 コスメディ製薬株式会社 マイクロニードル用緊迫器具
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ２
US20220249822A1 (en) * 2021-02-11 2022-08-11 Tokitae, LLC Applicator for Intradermal Microneedle Patches

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) * 1964-09-08 Means for vaccinating
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
GB2064329B (en) * 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
US4553541A (en) * 1981-03-23 1985-11-19 Becton, Dickinson And Co. Automatic retractable lancet assembly
EP0429842B1 (fr) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US6048337A (en) * 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
DE69505142T2 (de) 1994-08-18 1999-05-12 Nmt Group Plc, Bellshill, Lanarkshire Vorrichtungen zum zurückziehen von nadeln
CA2205444A1 (fr) * 1994-12-09 1996-06-13 Novartis Ag Systeme transdermique
WO1996037256A1 (fr) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Timbre micromecanique pour ameliorer l'administration de composes a travers la peau
WO1996037155A1 (fr) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Dispositif micromecanique et procede pour ameliorer l'administration percutanee de composes
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
US5613978A (en) 1996-06-04 1997-03-25 Palco Laboratories Adjustable tip for lancet device
DE69719761T2 (de) 1996-06-18 2003-12-18 Alza Corp., Palo Alto Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
AU3880697A (en) 1996-07-03 1998-01-21 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
US5983136A (en) 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
WO1998028037A1 (fr) * 1996-12-20 1998-07-02 Alza Corporation Dispositif et procede permettant d'ameliorer le flux d'agent transdermique
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
WO1999029365A1 (fr) * 1997-12-11 1999-06-17 Alza Corporation Dispositif renforçant le flux d'agents transdermiques
KR100572539B1 (ko) 1997-12-11 2006-04-24 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
KR100557261B1 (ko) 1997-12-11 2006-03-07 알자 코포레이션 경피성 작용제 유동률을 증진시키기 위한 장치
JP2002517300A (ja) 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション 微小針デバイスおよび製造方法ならびにそれらの使用
GB9817662D0 (en) * 1998-08-13 1998-10-07 Crocker Peter J Substance delivery
CA2376368C (fr) * 1999-06-08 2009-08-11 Altea Technologies, Inc. Appareil pour creer des micropores dans des membranes biologiques a l'aide d'interfaces de tissus minces, et procede associe
US6364889B1 (en) * 1999-11-17 2002-04-02 Bayer Corporation Electronic lancing device
AU2088301A (en) * 1999-12-16 2001-06-25 Alza Corporation Device for enhancing transdermal flux of sampled agents
MXPA03003303A (es) 2000-10-13 2004-12-13 Johnson & Johnson Retenedor del miembro de microprotrusion para aplicador de impacto.
CZ20031035A3 (cs) 2000-10-13 2004-02-18 Alza Corporation Nárazový aplikátor opatřený množinou mikročepelek
KR20030068136A (ko) 2000-10-13 2003-08-19 알자 코포레이션 미세 돌기부로 피부를 천공하기 위한 장치 및 방법
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US6821281B2 (en) * 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
WO2002094368A1 (fr) 2000-10-26 2002-11-28 Alza Corporation Dispositifs d'administration de medicament transdermique avec des microprotrusions enrobees
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
ATE444773T1 (de) 2001-04-20 2009-10-15 Alza Corp Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält
US6591124B2 (en) * 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
EP1485317A2 (fr) 2001-11-30 2004-12-15 Alza Corporation Procedes et appareils de formation de grilles de microprojections
RU2314760C2 (ru) 2001-12-20 2008-01-20 Алза Корпорейшн Микровыступы, пробивающие кожу, имеющие средство регулирования глубины пробивки
KR20050054483A (ko) 2002-06-28 2005-06-10 알자 코포레이션 코팅된 미세돌출부를 갖는 경피용 약물 전달 장치
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
CA2530531A1 (fr) 2003-06-30 2005-01-20 Alza Corporation Formulations pour microprojections revetues contenant des contre-ions non volatils
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
EP1677687A4 (fr) 2003-10-28 2008-09-17 Alza Corp Administration de conjugues polymeres de peptides et de proteines therapeutiques par le biais de microprotuberances revetues
WO2005044333A2 (fr) 2003-10-31 2005-05-19 Alza Corporation Applicateur a actionnement automatique pour reseau de micro-protuberances
BRPI0416042A (pt) 2003-11-13 2007-01-02 Alza Corp composição e aparelho para suprimento transdérmico
JP5007427B2 (ja) 2004-05-13 2012-08-22 アルザ コーポレイション 副甲状腺ホルモン剤の経皮送達のための装置および方法

Also Published As

Publication number Publication date
CA2425315C (fr) 2010-01-12
US20020123675A1 (en) 2002-09-05
MXPA03003299A (es) 2004-12-13
CZ20031037A3 (cs) 2003-10-15
CA2425315A1 (fr) 2002-04-18
AU2001296828B2 (en) 2005-11-24
JP4659332B2 (ja) 2011-03-30
CN1479590A (zh) 2004-03-03
NO20031681D0 (no) 2003-04-11
BR0114629A (pt) 2004-01-20
RU2275871C2 (ru) 2006-05-10
PL360998A1 (en) 2004-09-20
NO20031681L (no) 2003-06-13
DE60138411D1 (de) 2009-05-28
ZA200303633B (en) 2004-05-12
EP1341453A1 (fr) 2003-09-10
ES2324461T3 (es) 2009-08-07
NZ525294A (en) 2005-02-25
WO2002030301A1 (fr) 2002-04-18
AU9682801A (en) 2002-04-22
US7798987B2 (en) 2010-09-21
KR20030068136A (ko) 2003-08-19
ATE428357T1 (de) 2009-05-15
IL155374A0 (en) 2003-11-23
US7131960B2 (en) 2006-11-07
CN1250171C (zh) 2006-04-12
HUP0303558A2 (en) 2004-01-28
US20050234401A1 (en) 2005-10-20
JP2004510535A (ja) 2004-04-08
EP1341453B1 (fr) 2009-04-15

Similar Documents

Publication Publication Date Title
MA26057A1 (fr) Appareil et procédé de perçage de peau par microdents
BR0312671A (pt) Dispositivo de microagulhas, método para utilizar um dispositivo de microagulhas, e, método para aplicar um dispositivo de microagulhas
MXPA03003815A (es) Dispositivos de suministro transdermico de farmaco que tienen microrresaltos recubiertos.
DE60213815D1 (de) Elektronische karte für die transdermale arzneimittelabgabe und analytenextraktion
WO2005042054A3 (fr) Procede et systeme de pretraitement permettant d'ameliorer l'administration transdermique de medicaments
AU2088301A (en) Device for enhancing transdermal flux of sampled agents
WO2004105729A3 (fr) Dispositif d'administration de vaccin transdermique revetu de micro-protuberances
MXPA06013168A (es) Aparato y metodo para el suministro transdermico de agentes de la hormona paratiroidea.
CN101287517A (zh) 用于借助微凸起刺穿皮肤的设备和方法
TW200600132A (en) Frequency assisted transdermal agent delivery method and system
TW200502017A (en) Active agent delivery device having composite members
WO2005051455A3 (fr) Procede et systeme d'administration de vaccin transdermique assiste par ultrasons
IL155389A0 (en) Microprotrusion member retainer for impact applicator
TW200605929A (en) Method and apparatus for reducing the incidence of tobacco use
AU2001275260A1 (en) Method and apparatus for enhancing penetration of a puncturing member into the intradermal space
IL158480A0 (en) Microprojection array having a beneficial agent containing coating
WO2004030743A3 (fr) Methode et dispositif d'administration de medicaments presentant des microprojections revetues comprenant des vasoconstricteurs
TW200602099A (en) Apparatus and method for transdermal delivery of fentanyl-based agents
IL136008A0 (en) Electrically-mediated transdermal drug injection
TW200621316A (en) Apparatus and method for transdermal delivery of vascular endothelial growth factors
TW200738252A (en) Apparatus and method for transdermal delivery of Epoetin-based agents
TW200602019A (en) Apparatus and method for transdermal delivery of parathyroid hormone agents