MA24062A1 - Heteroatome comprenant des cyclopentano-pyridile oxazolidinones - Google Patents

Heteroatome comprenant des cyclopentano-pyridile oxazolidinones

Info

Publication number: MA24062A1
Authority: MA; Morocco
Prior art keywords: pyridile; cyclopentano; heteroatome; oxazolidinones; pyridile oxazolidinones
Prior art date: 1996-01-18

Application number

MA24463A

Other languages

English (en)

Inventor

Stolle Andreas

Bartel Stephan

Ruppelt Martin

Kroll Hein-Peter

Endermann Rainer

Habich Dieter

Guarnieri Walter

Riedl Bernd

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-18

Filing date

1997-01-14

Publication date

1997-10-01

1997-01-14 Application filed by Bayer Ag filed Critical Bayer Ag

1997-10-01 Publication of MA24062A1 publication Critical patent/MA24062A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

MA24463A 1996-01-18 1997-01-14 Heteroatome comprenant des cyclopentano-pyridile oxazolidinones MA24062A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19601627A DE19601627A1 (de)	1996-01-18	1996-01-18	Heteroatomhaltige Cyclopentanopyridyl-Oxazolidinone

Publications (1)

Publication Number	Publication Date
MA24062A1 true MA24062A1 (fr)	1997-10-01

Family

ID=7783042

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MA24463A MA24062A1 (fr)	1996-01-18	1997-01-14	Heteroatome comprenant des cyclopentano-pyridile oxazolidinones

Country Status (21)

Country	Link
US (1)	US5869659A (fr)
EP (1)	EP0785201A1 (fr)
JP (1)	JPH09202787A (fr)
KR (1)	KR970059170A (fr)
AU (1)	AU1012397A (fr)
BG (1)	BG101139A (fr)
BR (1)	BR9700716A (fr)
CA (1)	CA2195177A1 (fr)
CZ (1)	CZ15897A3 (fr)
DE (1)	DE19601627A1 (fr)
EE (1)	EE9700020A (fr)
HU (1)	HU9700152D0 (fr)
IL (1)	IL120016A0 (fr)
MA (1)	MA24062A1 (fr)
NO (1)	NO970210L (fr)
PL (1)	PL317985A1 (fr)
SG (1)	SG50001A1 (fr)
SK (1)	SK6997A3 (fr)
TN (1)	TNSN97010A1 (fr)
TR (1)	TR199700039A2 (fr)
ZA (1)	ZA97393B (fr)

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US7002020B1 (en)	1998-01-23	2006-02-21	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
CN1288462A (zh)	1998-01-23	2001-03-21	法玛西雅厄普约翰美国公司	噁唑烷酮组合库、组合物和制备方法
US6562844B2 (en)	1998-01-23	2003-05-13	Pharmacia & Upjohn Company	Oxazolidinone combinatorial libraries, compositions and methods of preparation
KR20010052615A (ko) *	1998-06-05	2001-06-25	다비드 에 질레스	옥사졸리디논 유도체, 이것의 제조 방법 및 이것을함유하는 약학 조성물
US6441005B1 (en) *	1999-07-28	2002-08-27	Pharmacia & Upjohn Company	Oxazolidinone compounds and compositions, and methods of using the same
GB9928568D0 (en)	1999-12-03	2000-02-02	Zeneca Ltd	Chemical compounds
US6514529B2 (en)	2000-03-22	2003-02-04	Pharmacia & Upjohn Company	Oxazolidinone tablet formulation
MY127336A (en)	2000-03-22	2006-11-30	Upjohn Co	Container for linezolid iv solution
GB0009803D0 (en) *	2000-04-25	2000-06-07	Astrazeneca Ab	Chemical compounds
US6544991B2 (en)	2000-06-30	2003-04-08	Pharmacia & Upjohn Company	Compositions and methods for treating bacterial infections
US6423844B1 (en)	2001-06-06	2002-07-23	The United States Of America As Represented By The Secretary Of The Navy	Process for making 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-triamine
AR038536A1 (es) *	2002-02-25	2005-01-19	Upjohn Co	N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) *	2002-02-25	2006-11-28	Pfizer, Inc.	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
DE60304360T2 (de) *	2002-08-12	2006-11-16	Pharmacia & Upjohn Co. Llc, Kalamazoo	N-aryl-2-oxazolidinone und deren derivate
AR042086A1 (es) *	2002-11-21	2005-06-08	Upjohn Co	N-aril-2- oxazolidinon -5- carboxamidas y sus derivados, usados como agentes antibacterianos
JP2006516989A (ja) *	2003-02-07	2006-07-13	ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー	抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
BRPI0407252A (pt) *	2003-02-07	2006-01-31	Warner Lambert Co	Agentes antibacterianos.
US7012088B2 (en) *	2003-02-24	2006-03-14	Pharmacia & Upjohn Company	Indolone oxazolidinones and derivatives thereof
US20040204463A1 (en) *	2003-04-01	2004-10-14	Harris Christina Renee	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US7304050B2 (en) *	2003-09-16	2007-12-04	Pfizer Inc.	Antibacterial agents
WO2005082900A2 (fr) *	2004-01-28	2005-09-09	Pharmacia & Upjohn Company Llc	Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens
AU2005270951A1 (en) *	2004-08-06	2006-02-16	Pharmacia & Upjohn Company Llc	Oxazolidinones containing oxindoles as antibacterial agents
RU2478635C2 (ru) *	2006-10-19	2013-04-10	СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи	Гетероарильные соединения, содержащие их композиции и способы лечения с применением этих соединений
US8110578B2 (en)	2008-10-27	2012-02-07	Signal Pharmaceuticals, Llc	Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
CN106117213B (zh)	2009-10-26	2022-03-18	西格诺药品有限公司	杂芳基化合物及其合成和纯化方法
TWI713752B (zh)	2011-10-19	2020-12-21	標誌製藥公司	以ｔｏｒ激酶抑制劑治療癌症
US9403829B2 (en)	2011-12-02	2016-08-02	Signal Pharmaceuticals, Llc	Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-b]pyrazin-2(1H)-one, a solid form thereof and methods of their use
EP2817029B1 (fr)	2012-02-24	2019-07-10	Signal Pharmaceuticals, LLC	Procédés de traitement du cancer du poumon non à petites cellules à l'aide d'une thérapie combinée d'inhibiteur de kinase
AU2013203714B2 (en)	2012-10-18	2015-12-03	Signal Pharmaceuticals, Llc	Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity
CN105188704B (zh)	2013-01-16	2017-09-19	西格诺药品有限公司	被取代的吡咯并嘧啶化合物、其组合物和使用其的治疗方法
BR112015026021A2 (pt)	2013-04-17	2017-07-25	Signal Pharm Llc	terapia de combinação compreendendo um inibidor de tor quinase e n-(3-(5-flúor-2-(4-(2-met-oxietoxi)fenilamino)pirimidin-4-ilamino)fenil)acrilamida para o tratamento de câncer
WO2014172436A1 (fr)	2013-04-17	2014-10-23	Signal Pharmaceuticals, Llc	Polythérapie comprenant un inhibiteur de kinase tor et un composé de quinazolinone substitué en 5 pour le traitement du cancer
CN113730412A (zh)	2013-04-17	2021-12-03	西格诺药品有限公司	用二氢吡嗪并-吡嗪治疗癌症
CN105392499B (zh)	2013-04-17	2018-07-24	西格诺药品有限公司	用于治疗癌症的包含tor激酶抑制剂和胞苷类似物的组合疗法
US9937169B2 (en)	2013-04-17	2018-04-10	Signal Pharmaceuticals, Llc	Methods for treating cancer using dihydropyrazino-pyrazine compound combination therapy
EA030726B1 (ru)	2013-04-17	2018-09-28	СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи	ФАРМАЦЕВТИЧЕСКИЕ СОСТАВЫ, СПОСОБЫ, ТВЕРДЫЕ ФОРМЫ И СПОСОБЫ ПРИМЕНЕНИЯ, ОТНОСЯЩИЕСЯ К 1-ЭТИЛ-7-(2-МЕТИЛ-6-(1H-1,2,4-ТРИАЗОЛ-3-ИЛ)ПИРИДИН-3-ИЛ)-3,4-ДИГИДРОПИРАЗИНО[2,3-b]ПИРАЗИН-2(1H)-ОНУ
BR112015026292B1 (pt)	2013-04-17	2022-04-12	Signal Pharmaceuticals, Llc	Uso de 1-etil-7-(2-metil-6-(1h-1,2,4-triazol-3-il)piridin-3-il)-3,4-dihidropirazino [2,3-b]pirazin-2(1h)- ona e métodos in vitro
MX2015015880A (es)	2013-05-29	2016-05-31	Signal Pharm Llc	Composiciones farmaceuticas de 7-(6-(2-hidroxipropan-2-il)piridin- 3-il)-1-((trans)-4-metoxiciclohexil)-3,4-dihidropirazino[2,3-b]pi razin-2(1h)-ona, una forma solida del mismo y metodos de su uso.
NZ714742A (en)	2014-04-16	2017-04-28	Signal Pharm Llc	Solid forms of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one, compositions thereof and methods of their use
WO2015160880A1 (fr)	2014-04-16	2015-10-22	Signal Pharmaceuticals, Llc	Formes solides comprenant 1-éthyl-7-(2-méthyl-6-(1h-1,2,4-triazol-3-yl) pyridin-3-yl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1h)-one, et co-formateur, compositions et procédés d'utilisation de ces dernières
WO2015160882A1 (fr)	2014-04-16	2015-10-22	Signal Pharmaceuticals, Llc	Formes solides comprenant de la 7-(6- (2-hydroxypropan-2-yl) pyridin-3-yl)-1-(trans)-4-méthoxycyclohexyl)-3, 4-dihydropyrazino[2,3-b] pyrazin-2(1h)-one, et un co-formeur, leurs compositions et leurs procédés d'utilisation
US9737535B2 (en)	2014-04-16	2017-08-22	Signal Pharmaceuticals, Llc	Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines
NZ629796A (en)	2014-07-14	2015-12-24	Signal Pharm Llc	Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use
EA201790189A1 (ru)	2014-07-14	2017-11-30	СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи	Способы лечения злокачественного новообразования с использованием замещенных пирролопиримидиновых соединений, композиции на их основе
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US5164510A (en) *	1988-09-15	1992-11-17	The Upjohn Company	5'Indolinyl-5β-amidomethyloxazolidin-2-ones
EP0609905B1 (fr)	1988-09-15	2001-06-06	PHARMACIA & UPJOHN COMPANY	3-Phényl azoté-5-bêta-amidométhyl-oxazolidine-2-ones
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JP2669579B2 (ja) *	1991-10-23	1997-10-29	エーザイ株式会社	オキサゾリドン誘導体
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1996
- 1996-01-18 DE DE19601627A patent/DE19601627A1/de not_active Withdrawn
1997
- 1997-01-07 EP EP97100114A patent/EP0785201A1/fr not_active Withdrawn
- 1997-01-10 AU AU10123/97A patent/AU1012397A/en not_active Abandoned
- 1997-01-13 US US08/785,145 patent/US5869659A/en not_active Expired - Fee Related
- 1997-01-14 MA MA24463A patent/MA24062A1/fr unknown
- 1997-01-15 TN TNTNSN97010A patent/TNSN97010A1/fr unknown
- 1997-01-15 CA CA002195177A patent/CA2195177A1/fr not_active Abandoned
- 1997-01-15 SG SG1997000082A patent/SG50001A1/en unknown
- 1997-01-16 IL IL12001697A patent/IL120016A0/xx unknown
- 1997-01-16 PL PL97317985A patent/PL317985A1/xx unknown
- 1997-01-16 EE EE9700020A patent/EE9700020A/xx unknown
- 1997-01-16 JP JP9017765A patent/JPH09202787A/ja active Pending
- 1997-01-16 BG BG101139A patent/BG101139A/xx unknown
- 1997-01-17 TR TR97/00039A patent/TR199700039A2/xx unknown
- 1997-01-17 NO NO970210A patent/NO970210L/no unknown
- 1997-01-17 BR BR9700716A patent/BR9700716A/pt unknown
- 1997-01-17 SK SK69-97A patent/SK6997A3/sk unknown
- 1997-01-17 CZ CZ97158A patent/CZ15897A3/cs unknown
- 1997-01-17 ZA ZA97393A patent/ZA97393B/xx unknown
- 1997-01-17 KR KR1019970001266A patent/KR970059170A/ko not_active Withdrawn
- 1997-01-17 HU HU9700152A patent/HU9700152D0/hu unknown

Also Published As

Publication number	Publication date
NO970210D0 (no)	1997-01-17
TR199700039A2 (tr)	1997-08-21
AU1012397A (en)	1997-07-24
HU9700152D0 (en)	1997-03-28
ZA97393B (en)	1997-07-17
SG50001A1 (en)	1998-06-15
BR9700716A (pt)	1998-10-06
EP0785201A1 (fr)	1997-07-23
DE19601627A1 (de)	1997-07-24
MX9700388A (es)	1997-07-31
US5869659A (en)	1999-02-09
SK6997A3 (en)	1997-09-10
PL317985A1 (en)	1997-07-21
IL120016A0 (en)	1997-04-15
BG101139A (en)	1998-04-30
JPH09202787A (ja)	1997-08-05
CA2195177A1 (fr)	1997-07-19
TNSN97010A1 (fr)	2005-03-15
CZ15897A3 (en)	1997-08-13
EE9700020A (et)	1997-08-15
KR970059170A (ko)	1997-08-12
NO970210L (no)	1997-07-21

Publication	Publication Date	Title
MA24062A1 (fr)	1997-10-01	Heteroatome comprenant des cyclopentano-pyridile oxazolidinones
FR2746302B1 (fr)	1998-12-24	Compositions cosmetiques comprenant des nanopigments
DE69721098D1 (de)	2003-05-28	Entwicklungsgerät
DE69720097D1 (de)	2003-04-30	Entwicklungsgerät
DE69715313D1 (de)	2002-10-17	Entwicklungsgerät
IT1291486B1 (it)	1999-01-11	Corpo portante.
DK0800783T3 (da)	2001-11-05	Gulvrenseapparat
ZA981579B (en)	1999-03-17	Oxazolidinones
NL1001127C1 (nl)	1996-04-09	Bevestigingsinrichting.
FR2718478B1 (fr)	1996-07-05	Plinthe démontable.
DE59710679D1 (de)	2003-10-09	Lüfter
EP0665613A3 (fr)	1997-04-02	Assemblage d'un détecteur démontable.
TR199501336A2 (tr)	1996-06-21	Talim tertibati.
FR2746301B1 (fr)	1998-04-30	Compositions cosmetiques comprenant des nanopigments
FI3488U1 (fi)	1998-07-30	Pitolaite
IT237397Y1 (it)	2000-09-13	Elettrodomestico
DE59509813D1 (de)	2001-12-13	Substituierte oxazoline
FR2724100B1 (fr)	1997-09-19	Oreiller de soutien.
FR2716348B1 (fr)	1996-05-03	Coiffe réglable.
IT1287807B1 (it)	1998-08-18	Dispositivo di fissaggio di corpo rotante.
FR2721514B1 (fr)	1996-09-06	Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines.
ES1035520Y (es)	1997-11-16	Almohada compleja.
ITBO940383A0 (it)	1994-08-03	Apparecchio magneto-terapeutico.
ITSV970017A0 (it)	1997-04-02	Dispositivo sterilizzatore perfezionato.
ES1038076Y (es)	1998-11-01	"dispositivo atrapa-moscas".