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Rowan et al., 2013 - Google Patents

Preparative access to medicinal chemistry related chiral alcohols using carbonyl reductase technology

Rowan et al., 2013

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Document ID
4635865626919685764
Author
Rowan A
Moody T
Howard R
Underwood T
Miskelly I
He Y
Wang B
Publication year
Publication venue
Tetrahedron: Asymmetry

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Snippet

Libraries of highly enantioenriched secondary alcohols in both enantiomeric forms were synthesised by enzymatic reduction of their parent ketones using selectAZyme™ carbonyl reductase (CRED) technology. Commercially available CREDs were able to reduce a range …
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