Not the same in my case. I am using an external monitor, but it is constantly connected to my MacBook Pro, I do not change or connect/disconnect. Nevertheless the Opera gets unresponsive.
Your browser does not seem to support JavaScript. As a result, your viewing experience will be diminished, and you have been placed in read-only mode.
Please download a browser that supports JavaScript, or enable it if it's disabled (i.e. NoScript).