Sci-Hub

1783011177

The zoogeography of the freshwater mussels of the Taconic and southern Green mountain region of northeastern North America (Mollusca: Pelecypoda: Unionacea)

Can. J. Zool., 1982

The Taconic and southern Green mountains form a system of ridges drained by four watersheds in eastern New York and western New England: Lake Champlain and the Housatonic, Hudson, and Connecticut rivers. Ten species of mussels distributed among the Margaritiferidae and Unionidae are recorded, based on museum records and recent collections, from the area. The presence of species representing two regional faunas, the Mississippian and Northern Atlantic Slope, indicates that some western streams of the Taconic Mountain region were connected with both the Atlantic coastal and interior Mississippian drainages during the Late Pleistocene. However, a divide has persisted along the north–south trend of the two mountain chains that has prevented late glacial east�...

1783011177

Enzymatic hydrolysis of microcrystalline cellulose and pretreated wheat straw: A detailed comparison using convenient kinetic analysis

Bioresource Technology, 2013

Marked slow-down of soluble sugar production at low degree of substrate conversion limits the space-time yield of enzymatic hydrolysis of ligno-cellulosic materials. A simple set of kinetic descriptors was developed to compare reducing sugar release from pure crystalline cellulose (Avicel) and pretreated wheat straw by Trichoderma reesei cellulase at 50 °C. The focus was on the rate-retarding effect of maximum hydrolysis rate at reaction start (r(max)), limiting hydrolysis rate (r(lim)) at extended reaction time (24h), and substrate conversion, marking the transition between the r(max) and r(lim) kinetic regimes (C(trans)). At apparent saturation of substrate (12.2g cellulose/L) with enzyme, r(max) for pretreated wheat straw (~9.6g/L/h) surpassed that for A...

1783011176

High‐resolution mapping of epilepsy prevalence, ambulance use, and socioeconomic deprivation in an urban area of Sweden

Epilepsia, 2019

Geographic differences in epilepsy prevalence between areas of different socioeconomic standing have been demonstrated in the United Kingdom, but knowledge from other health care systems is scarce. Our objective was to compare epilepsy prevalence and emergency medical service (EMS) assignments for seizures in areas of different socioeconomic standings in the urban area of Gothenburg.Register-based study in Gothenburg (population 690 000), the second largest city in Sweden. Epilepsy cases were identified in the comprehensive national patient register in 2014-2015. EMS assignments were identified in the EMS dispatch system in 2013-2018. Socioeconomic variables were mean income and proportion of welfare recipients.Significant correlations were seen between epil...

1783011176

A First-Principles Study on Water Flow Through Single-Walled Carbon Nanotubes Using Artificial Neural Network Method

j nanosci nanotechnol, 2011

Ab initio molecular dynamics simulations are done to elucidate the electronic structure and properties of water/single-walled carbon nanotubes (SWCNTs) systems. The artificial neural network (ANN) approach and statistical methods are then used to model and analyze these properties. The ANN method substantially speeds up the ab initio electronic structure calculations and has superior accuracy in mimicking the results of such calculations. We aim to understand the effects of CNT chirality, temperature, and CNT flexibility on the water diffusion inside SWCNTs. In this regard, the CNT is fixed implies that the position of CNT is kept constant during the diffusion process. Statistical analysis of results shows that there is a nonmonotonic variation of diffusion ...

1783011176

The initiation and development of a group for relatives of patients with chronic emotional disorders

Group, 1981

This paper describes the initiation and development of an educational discussion group for relatives of patients with chronic emotional problems and the process by which it became transformed into a group combining a self-help, modified therapy model with a primary focus on the members' interaction with their patientrelatives. The group offered the opportunity to ventilate pent up emotions in a supportive, reality-oriented context and provided information and education about the nature of emotional disorders. Generally this helped family members to effect positive changes in their interactions with their patient-relatives; to accept with greater understanding their relatives' illness; and to better evaluate the quality of treatment their relatives were recei...

1783011175

LACK OF TASK DIFFERENTIATION DURING PREY CAPTURE IN THE GROUP LIVING SPIDER STEGODYPHUS MIMOSARUM (ARANEAE, ERESIDAE)

J Arachnol, 2002

Stegodyphus mimosarum of the African savanna form communal nests consisting of few to several hundred individuals and co-operate in nest construction and maintenance, brood care and prey capture. We tested large and small individuals for differential responses to different prey risk types. To date, there has been no conclusive evidence of tasking in these or other social spiders. If tasking occurs, small spiders should approach and attempt to subdue less dangerous prey items such as flies more often than the more dangerous prey items such as bees. Hungry individuals were significantly more willing to venture out of the nest refuge and thus accept the costs associated with prey capture than were satiated spiders. Apparent depletion of poison in previous prey ...

1783011175

A Novel Sequential-Stage Optimization Strategy for an Interior Permanent Magnet Synchronous Generator Design

IEEE Trans. Ind. Electron., 2018

For an optimal design of an interior permanent magnet synchronous generator (IPMSG) for range the extended electric vehicle (REEV), many design variables and objective functions should be considered. Conventional optimization methods like the Taguchi method and multiobjective optimization algorithm have completeness or calculation time problems when solving the many design variables and objectives problems. To address these problems, a sequential-stage optimization strategy (SSOS) is proposed. In the first stage of the SSOS, the initial design result considering the various objective functions is derived by using the Taguchi method. In addition, the sensitive design variables are sorted through the calculation of synthetic signal to noise. In the second stag...

1783011175

Amniotic membrane transplantation elicits goblet cell repopulation after conjunctival reconstruction in a case of severe ocular cicatricial pemphigoid

Acta Ophthalmologica Scandinavica, 2003

The surgical procedures used until now to rebuild the conjunctiva in patients affected by ocular cicatricial pemphigoid (OCP) have not demonstrated appreciable anatomical and functional success. This study reports the postoperative clinical and cytological outcomes of a human amniotic membrane transplantation (AMT) to rebuild the conjunctiva in a case of late stage OCP.We present a 75-year-old woman with a severe form of pemphigoid with entropion, trichiasis, symblepharon and blunting of the fornices, who underwent excision of the scarred and inflamed tissue covering the ocular surface and AMT.Our data show an improvement of the ocular surface condition, with reacquired fornix depth, reduced inflammation and presence of goblet cells at each follow-up.Amnioti...

1783011175

Overproduction of the extracellular lipase is closely related to that of metalloprotease in Serratia marcescens

Journal of Fermentation and Bioengineering, 1996

The recombinant strain of Serratia marcescens Sr41 carrying the lipA gene encoding the extracellular lipase on a high-copy-number plasmid, pUC19, overproduced lipase. The extracellular lipase activity of the hyperproducing strain reached 220,000 U/ml of the culture medium and was about 9-fold greater than that of the strain carrying pUC19. The extracellular protease activity of the lipase-hyperproducing recombinant strain was decreased by 90% compared with that of the strain carrying pUC19. Sodium dodecyl sulfate-polyacrylamide gel electrophoretic analysis revealed overproduction of the lipase and reduction of the extracellular metalloprotease production in the culture medium of the lipase-hyperproducing strain. The production of extracellular metalloproteas...

1783011175

Farmers’ Rural-To-Urban Migration, Influencing Factors and Development Framework: A Case Study of Sihe Village of Gansu, China

IJERPH, 2019

Farmers are the major participants in rural development process and their willingness to settle in urban areas directly affects the implementation of rural revitalization strategy. Based on Ostrom's institutional analysis and development (IAD) framework, we analyzed farmers' willingness to settle in urban areas and its influencing factors by binary Logistic regression and cluster analysis of survey data of 190 rural households in Sihe village of Gansu Province of China. The results show that: (1) In Sihe village, farmers' willingness to settle in urban areas was low in general and influenced by their neighbors' decisions or behaviors. Households willing and unwilling to migrate to urban areas both presented significant spatial agglomeration. (2) The factors ...

1783011174

Comparing the efficacy of field treatments for actinic keratosis: a critical appraisal of a randomized trial in the New England Journal of Medicine

Br J Dermatol, 2020

Jansen et al. conducted a randomized trial to compare the efficacy of four field treatments for actinic keratosis (AK). This was a multicentre, single‐blind, randomized trial conducted in the dermatology departments of four Netherlands hospitals. Patients were not blinded. The investigator who evaluated the trial outcome was blinded. This study included adult patients with at least five AKs on the face or vertex scalp. Patients were randomized to treatment with fluorouracil 5% cream, imiquimod 5% cream, methyl aminolaevulinate photodynamic therapy (MAL‐PDT) or ingenol mebutate 0·015% gel. The primary outcome was whether patients had ≥ 75% reduction in AK count 12 months after treatment. In total 624 patients participated. The likelihood of having ≥ ...

1783011174

Comfort Feeding Only: A Proposal to Bring Clarity to Decision‐Making Regarding Difficulty with Eating for Persons with Advanced Dementia

J American Geriatrics Society, 2010

Feeding and eating difficulties leading to weight loss are common in the advanced stages of dementia. When such problems arise, family members are often faced with making a decision regarding the placement of a percutaneous endoscopic gastrostomy tube. The existing evidence based on observational studies suggests that feeding tubes do not improve survival or reduce the risk of aspiration, yet the use of feeding tubes is prevalent in patients with dementia, and the majority of nursing home residents do not have orders documenting their wishes about the use of artificial hydration and nutrition. One reason is that orders to forgo artificial hydration and nutrition get wrongly interpreted as "do not feed," resulting in a reluctance of families to agree to them....

1783011174

Betulin Protects HT-22 Hippocampal Cells against ER Stress through Induction of Heme Oxygenase-1 and Inhibition of ROS Production

Natural Product Communications, 2019

A key pathologic event in neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease, is endoplasmic reticulum (ER) stress-induced neuronal cell death. ER stress-induced generation of reactive oxygen species (ROS) has been implicated in neurological disease processes. Betulin is one of the major triterpenoids found in Betula platyphylla that possesses several biological properties, including cytoprotective and antioxidative effects. Therefore, we investigated whether betulin could prevent ER stress-induced neurotoxicity in HT-22 hippocampal neuronal cells. We observed that betulin reduced the thapsigargin (TG, an ER stress inducer)-induced apoptosis of HT-22 cells. Moreover, the cytoprotective effects of betulin were comparable to th...

1783011173

Synthesis of Different Architectures Like Stars, Multipods, Ellipsoids and Spikes of Zinc Oxide by Surfactantless Precipitation

j nanosci nanotechnol, 2011

Zinc oxide with different morphologies like stars, multipods, ellipsoids and spikes was synthesized using zinc nitrate and sodium hydroxide in the absence of surfactants. Seed mediation was found to be essential for the formation of ZnO nanospikes. Synthesized ZnO samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), UV-visible diffuse reflectance spectroscopy (UV-vis-DRS) and energy dispersive analysis by X-rays (EDAX) techniques. The predominant c-axis growth of hexagonal lattice was observed in ZnO anisotropic particles. TEM analysis revealed the formation of two types of ZnO ellipsoid particles. Concentration of the reactants was found to have a role in control...

1783011173

Thermophilic anaerobic digestion of coffee grounds with and without waste activated sludge as co-substrate using a submerged AnMBR: System amendments and membrane performance

Bioresource Technology, 2013

Coffee grounds are deemed to be difficult for degradation by thermophilic anaerobic process. In this research, a 7 L AnMBR accepting coffee grounds was operated for 82 days and failed with pH dropping to 6.6. The deficiency of micronutrients in the reactor was identified. The system was recovered by supplying micronutrient, pH adjustment and influent ceasing for 22 days. In the subsequent 160 days of co-digestion experiment, waste activated sludge (15% in the mixture) was mixed into coffee grounds. The COD conversion efficiency of 67.4% was achieved under OLR of 11.1 kg-COD/m3 d and HRT of 20 days. Tannins was identified affecting protein degradation by a batch experiment. Quantitative supplements of NH4HCO3 (0.12 g-N/g-TSin) were effective to maintain alkal...

1783011172

Nature of the Intermediate Formed in the Reduction of O₂ to H₂O at the Trinuclear Copper Cluster Active Site in Native Laccase

J. Am. Chem. Soc., 2002

The multicopper oxidases contain at least four copper atoms and catalyze the four-electron reduction of O2 to H2O at a trinuclear copper cluster. An intermediate, termed native intermediate, has been trapped by a rapid freeze-quench technique from Rhus vernicifera laccase when the fully reduced form reacts with dioxygen. This intermediate had been described as an oxygen-radical bound to the trinuclear copper cluster with one Cu site reduced. XAS, however, shows that all copper atoms are oxidized in this intermediate. A combination of EXAFS, multifrequency EPR, and VTVH MCD has been used to understand how this fully oxidized trinuclear Cu cluster relates to the fully oxidized resting form of the enzyme. It is determined that in the native intermediate all cop...

1783011172

Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs

Aust Veterinary J, 2019

Swine dysentery (SD) caused by Brachyspira hyodysenteriae is an important disease in Australia.The aim of this study is to evaluate the macrolide antibiotic kitasamycin for use in SD control.The minimum inhibitory concentrations (MICs) of kitasamycin, tylosin and lincomycin for 32 Australian isolates of B. hyodysenteriae were evaluated. Mutations in the 23S rRNA gene were examined. Isolate '13' with a low kitasamycin MIC was used to challenge weaner pigs. Sixty pigs were housed in 20 pens each containing three pigs: pigs in four pens received 2 kg/tonne of a product containing kitasamycin (3.1% active) prophylactically in their food starting 4 days before B. hyodysenteriae challenge (group 1); pigs in four pens were challenged and received the same dose ther...

1783011172

Genotyping and population characteristics of the China Kadoorie Biobank

Cell Genomics, 2023

The China Kadoorie Biobank (CKB) is a population-based prospective cohort of >512,000 adults recruited from 2004 to 2008 from 10 geographically diverse regions across China. Detailed data from questionnaires and physical measurements were collected at baseline, with additional measurements at three resurveys involving ∼5% of surviving participants. Analyses of genome-wide genotyping, for >100,000 participants using custom-designed Axiom arrays, reveal extensive relatedness, recent consanguinity, and signatures reflecting large-scale population movements from recent Chinese history. Systematic genome-wide association studies of incident disease, captured through electronic linkage to death and disease registries and to the national health insurance system, ...

1783011171

Performance optimization of LQR‐based PID controller for DC‐DC buck converter via iterative‐learning‐tuning of state‐weighting matrix

Int J Numerical Modelling, 2019

This paper presents a numerically optimized linear-quadratic-regulator–based tuning mechanism for a ubiquitous proportional-integral-derivative controller to improve the output-voltage regulation capability of a direct-current (DC)-DC buck converter. The linear-quadratic-regulator minimizes the quadratic cost of variations in the control signal and error-dynamics of output-voltage to provide a trivial set of optimized proportional-integral-derivative controller gains in the form of the state-feedback gain vector. In order to further improve the controller's time-domain performance and its disturbance-rejection capability against load-transients and input-fluctuations, an iterative-learning-tuning mechanism is adopted to optimize the state-weighting matrix ...

1783011171

Seed train development for the fermentation of bagasse from sweet sorghum and sugarcane using a simplified fermentation process

Bioresource Technology, 2013

A process was developed for seed culture expansion (3.6 million-fold) using 5% of the hemicellulose hydrolysate from dilute acid pretreatment as the sole organic nutrient and source of sugar. Hydrolysate used for seed growth was neutralized with ammonia and combined with 1.0 mM sodium metabisulfite immediately before inoculation. This seed protocol was tested with phosphoric acid pretreated sugarcane and sweet sorghum bagasse using a simplified process with co-fermentation of fiber, pentoses, and hexoses in a single vessel (SScF). A 6 h liquefaction (L) step improved mixing prior to inoculation. Fermentations (L + SScF process) were completed in 72 h with high yields (>80 gal/US ton). Ethanol titers for this L + SScF process ranged from 24 g/L to 32 g/L, and...

1783011171

Capsaicin‐induced vasodilatation of human coronary arteries in vitro is mediated by calcitonin gene‐related peptide rather than substance P or neurokinin A

Acta Physiologica Scandinavica, 1989

In the present study the possible influence of capsaicin on human arterial coronary tone in vitro was studied in relation to the vasodilatory properties of calcitonin gene-related peptide (CGRP), substance P (SP) or neurokinin A (NKA). In addition, the influence of vasoactive intestinal polypeptide (VIP) and somatostatin (SOM) on the arteries was investigated. CGRP application to potassium-pre-contracted human epicardial coronary arteries (0.4–0.6 mm in inner diameter) induced a concentration-dependent, long-lasting relaxation. SP also relaxed these pre-contracted arteries, but the relaxation was transient and tachyphylaxis developed rapidly upon repeated administration. SP tachyphylaxis did not influence the relaxatory effects of CGRP. Furthermore, pre-in...

1783011171

Left Atrial Sphericity: A New Method to Assess Atrial Remodeling. Impact on the Outcome of Atrial Fibrillation Ablation

Cardiovasc electrophysiol, 2013

Atrial fibrillation (AF) ablation outcome is mainly determined by atrial remodeling that, nowadays, is only estimated through clinical presentation (persistent vs. paroxysmal) and left atrial (LA) dimension. The aim of the study was to stage the atrial remodeling process using the Left Atrial Sphericity (LASP) and determine whether this technique may help to predict AF ablation outcome.Consecutive patients who underwent contrast-enhanced cardiac magnetic resonance angiography before AF ablation were included in the study. Three-dimensional reconstruction of LA excluding pulmonary veins and the LA appendage was used to define the LA cavity. The LASP was automatically obtained with self-customized software.106 patients were included and categorized in 3 groups...

1783011171

Attached cultivation technology of microalgae for efficient biomass feedstock production

Bioresource Technology, 2013

The potential of microalgae biofuel has not been realized because of low productivity and high costs associated with the current cultivation systems. In this paper, an attached cultivation method was introduced, in which microalgae cells grew on the surface of vertical artificial supporting material to form algal film. Multiple of the algal films were assembled in an array fashion to dilute solar irradiation to facilitate high photosynthetic efficiency. Results showed that a broad range of microalgae species can grow with this attached method. A biomass productivity of 50–80 g m−2 d−1 was obtained outdoors for Scenedesmus obliquus, corresponding to the photosynthetic efficiency of 5.2–8.3% (total solar radiation). This attached method also offers lot...

1783011171

Compressed Air Energy Storage System Modeling for Power System Studies

IEEE Trans. Power Syst., 2019

In this paper, a detailed mathematical model of the diabatic compressed air energy storage (CAES) system and a simplified version are proposed, considering independent generators/motors as interfaces with the grid. The models can be used for power system steady-state and dynamic analyses. The models include those of the compressor, synchronous motor, cavern, turbine, synchronous generator, and associated controls. The configuration and parameters of the proposed models are based on the existing bulk CAES facilities of Huntorf, Germany. The models and performance of the CAES system are first evaluated with step responses, and then examined when providing frequency regulation in a test power system with high penetration of wind generation, comparing them with ...

1783011171

An energy efficient and spectrum efficient wireless heterogeneous network framework for 5G systems

IEEE Commun. Mag., 2014

In this article we explore a system framework of cooperative green heterogeneous networks for 5G wireless communication systems. We first survey the state-of-the-art on spectrum efficiency (SE), energy efficiency (EE), and quality of service (QoS) based mobile association, multi-layer interference management and power control, network wide cooperation and dynamic resource allocation for heterogeneous wireless networks. We also present the system framework of cooperative green heterogeneous networks, which aims at balancing and optimizing SE, EE, and QoS in heterogeneous wireless networks. We discuss the design principles and show some preliminary performance results on the tradeoffs among SE, EE, and QoS. Finally, we identify the technical challenges that re...

1783011170

Behavioural and sensory responses to drimane antifeedants in Pieris brassicae larvae

Entomologia Exp Applicata, 1996

Fifteen drimane compounds were tested for their feeding inhibiting activity in larvae of Pieris brassicae L. (Lepidoptera: Pieridae) when applied to leaf material of the host plant Brassica oleracea L. The antifeedant efficacy of the drimanes was related to their molecular structure in order to identify important functional groups. Of the drimanes tested, those with a lactone group on the B-ring were the most effective feeding inhibitors. Additionally, the sensory responses to 13 of the drimanes were measured. Neural activity was evoked in the deterrent cell in the medial sensillum styloconicum. Also, inhibition of sensory responses to feeding stimulants was found. Results of behavioural and electrophysiological tests were correlated in an attempt to elucida...

1783011170

A modified ninhydrin micro-assay for determination of total cyanogens in plants

Food Chemistry, 2013

Indirect quantification of total cyanogenic compounds (cyanogens) in plants was studied using a novel ninhydrin-based spectrophotometric micromethod. The ninhydrin–cyanide system obeys Beer’s law in the range from 20 μg L−1 to 800 μg L−1 CN− with molar absorptivity ε = 1.4 × 105 L mol−1 cm−1. Recovery at 100 μg L−1 CN− was 100.5 ± 0.1% and LOD and LOQ were 8 and 22 μg L−1, respectively. The conditions for ninhydrin reagent preparation were discussed. The extraction and separation solutions, extraction and incubation time, and solvent volume were also investigated for maximum recovery of total cyanogens. 0.1% NaHCO3 was used as an extraction solvent for cyanide formed after enzymatic hydrolysis of cyanogens. The procedure was suitab...

1783011170

Electrical Properties of Pyrolyzed and Electrochemically Lithium-Doped Poly(hydrazocarbonyl-1,4-phenylenecarbonyl) Film

Jpn. J. Appl. Phys., 1994

The carrier transport and detailed carbonization processes of pristine (poly (hydrazocarbonyl-1,4-phenylenecarbonyl):PHP) film have been investigated as a function of heat-treatment temperature (HTT). Formation of (poly(1,3,4-oxadiazole-2,5-diyl-1,4-phenylene):POP) at HTT=400°C is confirmed and explained by the dehydration reaction of PHP molecular structure. Conductivity (σ) increases by 20 orders of magnitude from 10 -18 S/cm with HTT of 1000°C. The enhancement of σ with HTT up to 600°C has been interpreted by the increase of localized charge carrier and the most prominent effect of the enhancement of σ by HTT above 800°C has been explained by not only the increase of carrier density but also the increase of mobility. Even in the sample of low HTT (...

1783011170

Simultaneous co-metabolic decolourisation of azo dye mixtures and bio-electricity generation under thermophillic (50 °C) and saline conditions by an adapted anaerobic mixed culture in microbial fuel cells

Bioresource Technology, 2013

In this study, azo dye adapted mixed microbial consortium was used to effectively remove colour from azo dye mixtures and to simultaneously generate bio-electricity using microbial fuel cells (MFCs). Operating temperature (20-50 °C) and salinity (0.5-2.5%w/v) were varied during experiments. Reactor operation at 50 °C improved dye decolourisation and COD removal kinetic constants by approximately 2-fold compared to the kinetic constants at 30 °C. Decolourisation and COD removal kinetic constants remained high (0.28 h(-1) and 0.064 h(-1) respectively) at moderate salinity (1%w/v) but deteriorated approximately 4-fold when the salinity was raised to 2.5% (w/v). Molecular phylogenetic analysis of microbial cultures used in the study indicated that both un-acc...

1783011170

Metabolite Profiling and Stable Isotope Tracing in Sorted Subpopulations of Mammalian Cells

Anal. Chem., 2016

Biological samples such as tissues, blood, or tumors are often complex and harbor heterogeneous populations of cells. Separating out specific cell types or subpopulations from such complex mixtures to study their metabolic phenotypes is challenging because experimental procedures for separation may disturb the metabolic state of cells. To address this issue, we developed a method for analysis of cell subpopulations using stable isotope tracing and fluorescence-activated cell sorting followed by liquid chromatography–high-resolution mass spectrometry. To ensure a faithful representation of cellular metabolism after cell sorting, we benchmarked sorted extraction against direct extraction. While peak areas differed markedly with lower signal for amino acids b...

1783011169

Self-compatibility and autogamy in ‘Guara’ almond

Journal of Horticultural Science, 1992

To evaluate self-compatibility and autogamy in ‘Guara’ almond, pollen tube growth and fruit set following hand pollination and fruit set in a caged tree were considered. Pollen tube growth after self- and cross-pollination was similar either at 15 or 20°C. Fruit set after hand pollination was almost identical for both self- and cross-pollination either in the open field or on the caged tree. Thus the ability of the own pollen to grow and to set fruit was assessed, showing its genetical self-compatibility. Natural fruit set in the caged tree was over 11%, which is low for a commercial crop, but it was compensated by the high bloom density of this cultivar. This set was also probably decreased by the cage environment and the lack of wind inside the cage, ...

1783011169

Comment on “Recurrent ischemic stroke: Incidence, predictors, and impact on”…

Acta Neurol Scand, 2019

Acta Neurologica ScandinavicaVolume 141, Issue 3 p. 259-259 REPLY Comment on “Recurrent ischemic stroke: Incidence, predictors, and impact on”… Andrej Netland Khanevski, Corresponding Author Andrej Netland Khanevski adjv@ihelse.net orcid.org/0000-0002-6371-628X Department of Neurology, Haukeland University Hospital, Bergen, NorwaySearch for more papers by this author Andrej Netland Khanevski, Corresponding Author Andrej Netland Khanevski adjv@ihelse.net orcid.org/0000-0002-6371-628X Department of Neurology, Haukeland University Hospital, Bergen, NorwaySearch for more papers by this author First published: 16 September 2019 https://doi.org/10.1111/ane.13168Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation Sh...

1783011169

Influence of temperature on corneas stored in culture medium. A comparative study using functional and morphological methods

Acta Ophthalmologica Scandinavica, 2003

To investigate the influence of storage temperature on corneal swelling and on endothelial morphology in cultured corneas.Forty-eight rabbit corneas were separated into four groups of 12. The corneas were stored in culture medium at 37 degrees (group 37), 34 degrees (group 34), 31 degrees (group 31) and 23 degrees (room temperature) (group 23), respectively. All the corneas were monitored by weight recordings on days 0, 1, 2, 3, 4 and 7. On day 7, corneas were prepared for scanning electron microscopy and endothelial cell counts were performed.Lowering the temperature of the culture medium resulted in less swelling. Both temperature and storage time had significant effects on corneal swelling (p < 0.001). On day 7, the observed mean weight increase was 131.2...

1783011168

The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat

Brain Research, 1971

It is well-accepted in neuroscience that animals process time internally to estimate the duration of intervals lasting between one and several seconds. More than 100 years ago, Henri Bergson nevertheless remarked that, because animals have memory, their inner experience of time is ever-changing, making duration impossible to measure internally and time a source of change. Bergson proposed that quantifying the inner experience of time requires its externalization in movements (observed or self-generated), as their unfolding leaves measurable traces in space. Here, studies across species are reviewed and collectively suggest that, in line with Bergson's ideas, animals spontaneously solve time estimation tasks through a movement-based spatialization of time. Mo...

1783011168

Self-Regulation and Academic Procrastination

The Journal of Social Psychology, 1995

Abstract The role of autonomous self-regulation as a predictor of academic procrastination was assessed. French-Canadian students from a junior college (N = 498) completed the Academic Motivation Scale as well as an academic procrastination scale and other measures (anxiety, self-esteem, and depression) that have been found to be related to fear of failure. Correlation results indicated that students with intrinsic reasons for pursuing academic tasks procrastinated less than those with less autonomous reasons (external regulation and amotivation). Regression results indicated that the measures of depression, self-esteem, and anxiety accounted for 14% of the variance in academic procrastination, whereas the self-regulation variables accounted for 25%. These r...

1783011168

CHACO outreach project: the development of a primary health care-based medical genetic service in an Argentinean province

J Community Genet, 2013

Dissemination of knowledge in genetics to be applied in medicine has created a growing need for capacity building in health care workers. The CAPABILITY ARGENTINA outreach project protocol was designed as a model to introduce genetics in areas without genetic services. Our aim was for genetic health care to become part of primary care in an Argentine province lacking genetic services. The program was innovative as professionals from the referral center (Garrahan Hospital S.A.M.I.C.) traveled to remote areas to train professionals through problem-based education. A logical framework was designed for a local needs assessment. Teaching materials (Powerpoint presentations, printed syllabus, and CD) and a web page were developed. A demonstration project was carri...

1783011168

Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer’s Disease Model via Canonical Wnt/β-Catenin Pathway

ACS Nano, 2013

Neurogenesis, a process of generation of new neurons, is reported to be reduced in several neurodegenerative disorders including Alzheimer's disease (AD). Induction of neurogenesis by targeting endogenous neural stem cells (NSC) could be a promising therapeutic approach to such diseases by influencing the brain self-regenerative capacity. Curcumin, a neuroprotective agent, has poor brain bioavailability. Herein, we report that curcumin-encapsulated PLGA nanoparticles (Cur-PLGA-NPs) potently induce NSC proliferation and neuronal differentiation in vitro and in the hippocampus and subventricular zone of adult rats, as compared to uncoated bulk curcumin. Cur-PLGA-NPs induce neurogenesis by internalization into the hippocampal NSC. Cur-PLGA-NPs significantly inc...

1783011167

An electrophysiological in‐vivo study on the effects of nerve stimulation, drugs and denervation in the parotid gland of the rat

Acta Physiologica Scandinavica, 1989

Electrical stimulation of the sympathetic and parasympathetic nerves to the parotid gland of the rat gave rise to membrane potential changes. Responses were in several cases elicited by single stimuli which did not cause secretion. They were very similar to the ones seen after the administration of noradrenaline or acetylcholine. The peptides substance P (SP) and vasoactive intestinal polypeptide (VIP), in some cells, evoked membrane potential changes. The response was clearly enhanced during concurrent stimulation of the auriculotemporal nerve at a frequency below the secretory threshold. The membrane potential changes always occurred at stimulation frequencies or agonist doses that were lower or the same as those required for secretion. After atropine the ...

1783011167

Consensus statement for the management of generalized tonic‐clonic seizures in Spain

Acta Neurol Scand, 2019

Objective To develop recommendations for the management of patients with primary or secondary generalized tonic-clonic seizures (GTCS) based on best evidence and experience. Methods The Delphi methodology was followed. A multidisciplinary panel of 10 experts was established, who defined the scope, users and preliminary recommendations. Systematic and narrative reviews of the current literature were performed to assess data on the risk of sudden unexpected death in epilepsy and the efficacy and safety of add-on therapy in patients with GTCS. Twenty-five definitive recommendations were generated which were then graded on a scale of 1 (totally disagree) to 10 (totally agree) by the experts and 45 neurologists. Consensus was reached if at least 70% of the partic...

1783011167

Predicting the residual fatigue life of a cargo hull tank using a deep-learning technique

Journal of International Maritime Safety, Environmental Affairs, and Shipping, 2020

Unexpected loads are commonly applied in cargo ships when workers fail to comply with applicable regulations while loading and unloading cargo. This important factor can shorten the design life of a ship by increasing the possibility of structural damage. One way to improve the reliability of the fatigue life of a ship is to check for fatigue damage by observing real-time stress response depending on marine environmental conditions. Modern stress monitoring systems are installed in critical spots to capture stress signals and used to minimize the risk of crack occurrence.In the present study, a hull residual life prediction procedure was introduced by integrating traditional fatigue analysis and the stress response obtained from strain gauges installed in th...

1783011167

Aliasing artifacts reduction with subband signal analysis for demosaicked images

Digital Signal Processing, 2016

Abstract Demosaicking is a process used to estimate missing color values from the subsampled color filter array (CFA) image to reduce the cost and volume of a digital still camera. However, by sampling theory, it is known that subsampling a signal causes overlaps of signals in the frequency domain, which is known as aliasing. Most current demosaicking processes cannot completely solve aliasing problem resulting in aliasing artifacts such as false colors and zipper effects. In this paper, we propose an algorithm to remove these aliasing artifacts in demosaicked color images. A luminance image with minimum aliasing is obtained from the CFA image by using a low-pass kernel with cutoff frequencies determined by an approximate model for the Fourier spectrum. An a...

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Thermal effects of various drill materials during implant site preparation—Ceramic vs. stainless steel drills: A comparative in vitro study in a standardised bovine bone model

Clinical Oral Implants Res, 2020

Objectives The aim of this study was to evaluate thermal effects of ceramic and metal implant drills during implant site preparation using a standardised bovine model. Material and Methods A total of 320 automated intermittent osteotomies of 10- and 16-mm drilling depths were performed using zirconium dioxide-based and stainless steel drills. Various drill diameters (2.0/ 2.2, 2.8, 3.5, 4.2 mm ∅) and different cooling methods (without/ with external saline irrigation) were investigated at room temperature (21 ± 1°C). Temperature changes were recorded in real time using two custom-built multichannel thermoprobes in 1- and 2-mm distance to the osteotomy site. For comparisons, a linear mixed model was estimated. Results Comparing thermal effects, significan...

1783011166

On a new approach for constructing wormholes in Einstein–Born–Infeld gravity

Eur. Phys. J. C, 2016

We study a new approach for the wormhole construction in Einstein-Born-Infeld gravity, which does not require exotic matters in the Einstein equation. The Born-Infeld field equation is not modified from "coordinate independent" conditions of continuous metric tensor and its derivatives, even though the Born-Infeld fields have discontinuities in their derivatives at the throat in general. We study the relation of the newly introduced conditions with the usual continuity equation for the energy-momentum tensor and the gravitational Bianchi identity. We find that there is no violation of energy conditions for the Born-Infeld fields contrary to the usual approaches. The exoticity of energy-momentum tensor is not essential for sustaining wormholes. Some open prob...

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Reaction effect on the properties of poly(ethylene terephthalate) and poly(styrene- co -maleic anhydride) blends

Polymer, 2000

Poly(ethylene terephthalate) (PET) was blended with polystyrene (PS) and poly(styrene-co-maleic anhydride) (PScMA). The two blend systems were immiscible based on the glass transition temperatures measured by differential scanning calorimetry (DSC). In the case of 70 and 90% PScMA blends, the reaction between ester groups of PET and maleic anhydride (MAH) sites on PScMA occurred during melt mixing at 280°C for 30 min. The reaction was confirmed indirectly by thermal data, from the increase in the complex viscosity and from the solubility difference between the blends. The particle size in PET/PScMA reactive blends was smaller than that of the non-reactive blends. The mechanical properties such as tensile strength and modulus were not affected by the reactio...

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Increases in egg production in multiply mated female bushcrickets Leptophyes punctatissima are not due to substances in the nuptial gift

Ecological Entomology, 2003

Abstract. 1. A positive effect of the degree of polyandry on egg production is widespread in insects, particularly in species in which the male provides a nuptial gift. 2. This study aimed to determine whether or not this effect is due to females using nutrients from the nuptial gift (spermatophore and spermatophylax) to manufacture more eggs in the bushcricket Leptophyes punctatissima. 3. Females were permitted either a single or a double mating (with two different males) and, in both mating categories, were either prevented from consuming any part of the spermatophore or were permitted to consume the entire spermatophore. 4. Doubly mated females were found to lay over twice as many eggs over a 4-week period compared with singly mated females. This differen...

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Metastases in the ophthalmic region in Denmark 1969–98. A histopathological study

Acta Ophthalmologica Scandinavica, 2003

To evaluate the patterns of origin and anatomical localization of histologically verified metastases in the ophthalmic region in Denmark during 1969-98, and to compare the findings with those of a similar study for the period 1944-68.All metastatic lesions presented at the Eye Pathology Institute, University of Copenhagen during the period 1968-98 were investigated.Metastases were found in 81 specimens from the eye and eye region in 76 patients (32 men, 44 women). Five patients had bilateral involvement. The most frequent site of involvement was the uvea (63%), followed by the orbit (26%) and the eyelids (10%). Breast cancer accounted for the most frequent primary tumour (38%), followed by lung cancer (24%) and skin melanoma (14%).The pattern of anatomical l...

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Using sternal angle as anatomic landmark for right internal jugular vein catheterization in pediatrics

Acta Anaesthesiol Scand, 2019

Background Many formulas based on the patient's height, weight and/or age exist to determine central venous catheter (CVC) depth in children. However, this information is unavailable in some emergency conditions. Therefore, direct methods should be developed to guide catheter position in children. Methods Eighty patients aged 1-10 y were enrolled from July 2015 to August 2016 and seventy-five were completed; fifty were male, and twenty-five were female. The exclusion criteria were inability to identify the sternal angle or failure to use the right internal jugular vein approach. The catheter was inserted using the right internal jugular vein approach, the distance from the skin puncture point to the midpoint of the sternal angle plane was measured, and the c...

1783011164

Characterization of Superparamagnetic Iron Oxide Nanoparticles and Its Application in Protein Purification

j nanosci nanotechnol, 2011

The application of surface modified magnetic adsorbent particles in combination with magnetic separation techniques has received considerable awareness in recent years. There is a particular need in protein purification and analysis for specific, functional and generic methods of protein binding on solid supports. Nanoscale superparamagnetic iron oxide particles have been used to purify a natural coagulant protein extracted from Moringa oleifera seeds. Spectrophotometric analysis of the coagulant protein was performed using synthetic clay solution as substrate. Protein binding with carboxyl and silica surface modified superparamagnetic iron oxide nanoparticles (SPION) were compared with the known carboxyl methyl cellulose (CMC) beads of approximately 1 micro...

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Bouillon cube process design by applying product driven process synthesis

Chemical Engineering and Processing: Process Intensification, 2011

Abstract Unilever produces Knorr™ bouillon cubes for last several decades in various regions like Africa, Caribbean Islands, Central and Eastern Europe, and Russia etc. This high volume business generates revenues of an order of €1 bn/year. This article describes our approach for conceptual design of bouillon cube manufacturing process. Consumer attributes need to be taken into account while process design for such products. In this paper we used the product driven process synthesis approach for conceptual design of bouillon cube manufacturing process. In this approach we, based on the consumer attributes, defined the fundamental tasks to convert inputs (raw materials) into the desired outputs (bouillon cube microstructure). Given these fundamental task...

1783011164

Mitochondrial DNA polymorphisms in bipolar disorder

Journal of Affective Disorders, 2001

Previous studies suggested mitochondrial abnormality in bipolar disorder: (1) possible contribution of parent-of-origin effect in transmission of bipolar disorder; (2) abnormal brain phosphorus metabolism detected by phosphorus-31 magnetic resonance spectroscopy; (3) comorbidity of affective disorders in patients with mitochondrial encephalopathy; (4) increased levels of the 4977bp deletion of mitochondrial DNA (mtDNA) in the postmortem brains. We investigated mtDNA polymorphisms in association with bipolar disorder.Twelve PCR fragments including all tRNA genes were examined by the single-strand conformation polymorphism method in 43 bipolar patients. All observed polymorphisms were sequenced. Association of these polymorphisms with bipolar disorder was exam...

1783011164

First Step to Ellipsometry

IJP, 2014

Ellipsometry is a non-destructive, fast and accurate characterization technique used for determining the thickness and the optical constants of a material. However, this method has a drawback considering that the experimentally measured data are not meaningful in itself and one has to interpret the data based on modelling making ellipsometry dependent on the model selection, computation power/time and fitting. This makes ellipsometry, a difficult characterization method. However, it also presents a wonderful opportunity to apply the various topics taught in physics classes at undergraduate level. This paper provides the detailed insight into the self-standing film, the simplest case possible and hence the first step of ellipsometry experimentation which can ...

1783011164

Managing Insecticide Resistance by Mass Release of Engineered Insects

Journal of Economic Entomology, 2007

Transgenic crops producing insecticidal toxins are now widely used to control insect pests. The benefits of this method would be lost if resistance to the toxins spread to a significant proportion of the pest population. The primary resistance management method, mandatory in the United States, is the high-dose/refuge strategy, requiring toxin-free crops as refuges near the insecticidal crops, and the use of toxin doses sufficiently high to kill insects heterozygous for a resistance allele, thereby rendering resistance functionally recessive. We propose that mass-release of harmless susceptible (toxin-sensitive) insects could substantially delay or even reverse the spread of resistance. Mass-release of such insects is an integral part of release of insects ca...

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Effect of salt and sodium concentration on the anaerobic methanisation of the halophyte Tripolium pannonicum

Biomass and Bioenergy, 2016

The halophyte species Sea Aster (Tripolium pannonicum) was grown with different concentrations of artificial seawater. In a second experiment, T. pannonicum was cultivated with a nutrient solution containing different concentrations of NaCl. This halophyte biomass was used to determine the biogas production potential. According to the findings, it is possible to produce high yields of methane using biomass from halophytes cultivated in the presence of salt. Biogas and methane yield are influenced by the salt content of the plant tissue, however, high concentrations of salt in the anaerobic reactors itself inhibit the biogas and methane production. The highest methane yield is obtained using plant substrates grown at 22.5 g L−1 sea-salt with a value of 313 ...

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The study of left ventricular function from digitized echocardiograms

Progress in Cardiovascular Diseases, 1978

Genetic factors play an important role in linking insulin resistance and hypertension, also influencing insulin sensitivity changes during antihypertensive treatment. This study was aimed to evaluate whether genetic predisposition to hypertension can also influence left ventricular (LV) changes during antihypertensive treatment.We enrolled 36 never-treated hypertensives: 18 with both parents hypertensive (F+) and 18 with both parents normotensive (F−), matched for age, gender, and body mass index (BMI). The patients were evaluated twice, before and after 2.5 years of treatment with enalapril. At both evaluations the patients underwent: 24-h blood pressure (BP) monitoring, LV echocardiogram, and oral glucose tolerance test, with measurements of glucose and ...

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The chemical composition, digestibility, metabolisable energy content and nitrogen degradability of some protein concentrates

Animal Feed Science and Technology, 1994

One sample of copra expeller products, 11 of linseed meal, five of maize germ meal, one of whole maize germ, eight of malt culms, 11 of palm kernel meal, six of rapeseed meal, four of soyabean meal, five of soyabean meal (Brazilian), five of soyabean meal (high protein), two of whole soyabeans and nine of sunflower seed meal were evaluated by energy balance using wether sheep. Nitrogen degradability of a subpopulation of these samples (excluding maize germ, palm kernel and sunflower) was also measured. The crude protein contents of the feedstuffs ranged from 109 to 506 g kg−1 dry matter (DM). The digestible organic matter in the DM (DOMD) measured in vivo were all within the range 721–887 g kg−1, with the exception of sunflower seed meal (586 g kg−1)...

1783011163

The kinetics model and pyrolysis behavior of the aqueous fraction of bio-oil

Bioresource Technology, 2013

The pyrolysis behavior and kinetics of the aqueous fraction of bio-oil were studied through thermogravimetric (TG) analysis. Based on the experimental data, activation energies and kinetic parameters were calculated by the Achar differential method and the Coats-Redfern integral method, then the most probable mechanism functions and kinetics model were obtained at last. The results show that the pyrolysis of bio-oil aqueous fraction can be divided into three stages, that is, the volatilization of volatile fractions, the decomposition stage of heavy fractions and char combustion. The experimental results show that the activation energy of volatilization is higher than that of the decomposition stage. The first stage was expressed as the first order reaction a...

1783011163

Automatically Tracing Dependability Requirements via Term-Based Relevance Feedback

IEEE Trans. Ind. Inf., 2018

In many critical industrial information systems, tracking a dependability requirement is instrumental to the verification and validation (V&V) of security, privacy, and other dependability concerns. Automated traceability tools employ information retrieval methods to recover candidate links, which saves much manual effort. Integrating relevance feedback (RF) could potentially improve the retrieval effectiveness by soliciting the relevance judgments on a subset of the retrieval results and then incorporating the feedback into subsequent retrieval. However, little is known about how to use RF to trace dependability requirements. In this paper, we propose a novel term-based RF algorithm that leverages the term usage context to recommend positive and negative fe...

1783011162

Miniscrew-assisted rapid palatal expander (MARPE): the quest for pure orthopedic movement

Dental Press J. Orthod., 2016

The midpalatal suture has bone margins with thick connective tissue interposed between them, and it does not represent the fusion of maxillary palatal processes only, but also the fusion of palatal processes of the jaws and horizontal osseous laminae of palatal bones. Changing it implies affecting neighboring areas. It has got three segments that should be considered by all clinical analyses, whether therapeutic or experimental: the anterior segment (before the incisive foramen, or intermaxillary segment), the middle segment (from the incisive foramen to the suture transversal to the palatal bone ) and the posterior segment (after the suture transversal to the palatal bone ). Rapid palatal expansion might be recommended for patients at the final pubertal gro...

1783011162

Fear as a Disposition and an Emotional State: A Genetic and Environmental Approach to Out‐Group Political Preferences

American J Political Sci, 2013

Fear is a pervasive aspect of political life and is often explored as a transient emotional state manipulated by events or exploited by elites for political purposes. The psychological and psychiatric literatures, however, have also established fear as a genetically informed trait, and people differ in their underlying fear dispositions. Here we propose these differences hold important implications for political preferences, particularly toward out-groups. Using a large sample of related individuals, we find that individuals with a higher degree of social fear have more negative out-group opinions, which, in this study, manifest as anti-immigration and prosegregation attitudes. We decompose the covariation between social fear and attitudes and find the princ...

1783011162

Gastric cancer during pregnancy: A report on 13 cases and review of the literature with focus on chemotherapy during pregnancy

Acta Obstet Gynecol Scand, 2019

Introduction Gastric cancer during pregnancy is extremely rare and data on optimal treatment and possible chemotherapeutic regimens are scarce. The aim of this study is to describe the obstetric and maternal outcome of women with gastric cancer during pregnancy and review the literature on antenatal chemotherapy for gastric cancer. Material and methods Treatment and outcome of patients registered in the International Network on Cancer, Infertility and Pregnancy database with gastric cancer diagnosed during pregnancy were analyzed. Results In total, 13 women with gastric cancer during pregnancy were registered between 2002 and 2018. Median gestational age at diagnosis was 22 weeks (range 6-30 weeks). Twelve women were diagnosed with advanced disease and died ...

1783011162

The role of collagen in determining bone mechanical properties

Journal Orthopaedic Research, 2001

The hypothesis of this study was that collagen denaturation would lead to a significant decrease in the toughness of bone, but has little effect on the stiffness of bone. Using a heating model, effects of collagen denaturation on the biomechanical properties of human cadaveric bone were examined. Prior to testing, bone specimens were heat treated at varied temperatures (37-200 degrees C) to induce different degrees of collagen denaturation. Collagen denaturation and mechanical properties of bone were determined using a selective digestion technique and three-point bending tests, respectively. The densities and weight fractions of the mineral and organic phases in bone also were determined. A repeated measures analysis of variance showed that heating had a si...

1783011162

Thermal decomposition of the rare earth sulfates of cerium(III), cerium(IV), lanthanum(III) and samarium(III)

Applied Surface Science, 2003

Surface and bulk chemical and elemental composition of the rare earth sulfates of cerium(III), cerium(IV), lanthanum(III) and samarium(III) were characterized during various stages of thermal decomposition. Decomposition was conducted under both vacuum and atmospheric conditions. In situ analysis was conducted on samples decomposed in vacuum. As identified by X-ray diffraction, the bulk decomposition of all the rare earth sulfate samples to their corresponding oxide, in atmosphere, proceeded via the formation of an oxysulfate. For the exception of cerium(III) sulfate, similar results were obtained in thermogravimetric analysis. The thermal decomposition profile, as determined by X-ray microanalysis was similar to that observed in thermogravimetric analysis a...

1783011162

High performance bacterial fermentation process with two gaseous substrates

Acta Biotechnologica, 1992

Two methane utilizing bacteria strains, GB 21 and WSB 874, were cultivated with methane as sole carbon and energy source in a submerged continuous fermentation process. The aim of the investigations was to reach high biomass concentrations (>25 g BDM ·kg−1 medium) and high productivities (>3 g BDM · kg−1 · h−1). A precondition for the high-performance fermentation process was to ensure a transfer rate of methane and oxygen in quantities required by the microorganisms. For this purposes a high performance stirred pressure fermenter was used. The fermentation process is characterized by the transfer of two gaseous substrates. In order to develop a technical process it was necessary to investigate both the correlations between the two gases and the pro...

1783011161

Reassembled Graphene-Platelets Encapsulated Silicon Nanoparticles for Li-Ion Battery Anodes

j nanosci nanotechnol, 2011

Among lithium alloy metals, silicon is an attractive candidate to replace commercial graphite anode because silicon possesses about ten times higher theoretical energy density than graphite. However, electrically nonconducting silicon undergoes a large volume changes during lithiation/delithiation reactions, which causes fast loss of storage capacity upon cycling due to electrode pulverization. To alleviate these problems, electrodes comprising Si nanoparticles (20 nm) and graphene platelets, denoted as SiGP-1 (Si = 35.5 wt%) and SiGP-2 (Si = 57.6 wt%), have been prepared with low cost materials and using easily scalable solution-dispersion methods. X-ray diffraction (XRD), scanning electron microscopy (SEM) and high-resolution transmission electron microsco...

1783011161

The effects of aspirin and warfarin therapy on haemorrhage in vitreoretinal surgery

Acta Ophthalmologica Scandinavica, 2003

No substantial recommendations exist regarding the management of anticoagulant drugs prior to ocular surgery. Stopping anticoagulation can cause fatal emboli, but sight-threatening bleeds may occur if anticoagulation is continued. We examined the effects of anticoagulation on vitreoretinal surgery.Clinical details were prospectively entered on a database. The anticoagulant status of 541 consecutive patients undergoing vitreoretinal surgery was recorded.Sixty patients in the study were taking aspirin and seven were taking warfarin. There were 11 cases of choroidal haemorrhage, one of which involved a warfarin user. Of 325 retinal detachment repairs, 21 (6.5%) had preoperative vitreous haemorrhages. Two of these patients were on aspirin and two were on warfari...

1783011160

Measuring TSH receptor antibody to influence treatment choices in Graves’ disease

Clinical Endocrinology, 2017

TSH receptor antibody (TRAb) plays a key role in the pathogenesis of Graves' disease (GD), and its levels correlate with the clinical course. The second- and third-generation TRAb assays have >95% sensitivity and specificity for the diagnosis of GD and have improved the utility of TRAb to predict relapse. TRAb levels decline with antithyroid drug (ATD) therapy and after thyroidectomy. Its level increases for a year following radioactive iodine (RAI) therapy, with a gradual fall thereafter. TRAb level >12 IU/l at diagnosis of GD is associated with 60% risk of relapse at 2 years and 84% at 4 years. The prediction of risk of relapse improves further to >90% with TRAb >7·5 IU/l at 12 months or >3·85 IU/l at cessation of ATD therapy. TRAb tests are not expensiv...

1783011160

Butyric acid esterification kinetics over Amberlyst solid acid catalysts: The effect of alcohol carbon chain length

Bioresource Technology, 2013

The liquid phase esterification of butyric acid with a series of linear and branched alcohols is examined. Four strong cation exchange resins, Amberlyst™ 15, Amberlyst™ 36, Amberlyst™ BD 20, and Amberlyst™ 70, were used along with para-toluenesulfonic acid as a homogeneous catalyst. The effect of increasing alcohol carbon chain length and branching on esterification rate at 60°C is presented. For all catalysts, the decrease in turnover frequency (TOF) with increasing carbon chain length of the alcohol is described in terms of steric hindrance, alcohol polarity, and hydroxyl group concentration. The kinetics of butyric acid esterification with 2-ethylhexanol using Amberlyst™ 70 catalyst is described with an activity-based, pseudo-homogeneous kineti...

1783011160

Photodynamic therapy for esophageal lesions: selectivity depends on wavelength, power, and light dose

The Annals of Thoracic Surgery, 1999

Photodynamic therapy with 5-aminolevulinic acid-induced photosensitization could selectively eliminate esophageal epithelial lesions. This study aimed at optimizing laser parameters for 5-aminolevulinic acid photodynamic therapy of the normal rat esophagus.Sixty rats received 200 mg/kg 5-aminolevulinic acid orally and were illuminated 3 hours later with either 633 or 532 nm light (n = 30 for each group) through an endoesophageal balloon catheter. Rats received either 8.3 or 25 J/cm diffuser, applied with a 33, 100, or 300 mW/cm diffuser. During illumination, tissue fluorescence measurements and light dosimetry were done. Rats were sacrificed at 48 hours after photodynamic therapy.During illumination, protoporphyrin IX fluorescence declined faster when a high...

1783011160

Variability in odour reception in the peripheral sensory system of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)

Australian Journal of Entomology, 2007

Abstract Mixtures of single odours were used to explore the receptor response profile across individual antennae of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). Seven odours were tested including floral and green-leaf volatiles: phenyl acetaldehyde, benzaldehyde, β-caryophyllene, limonene, α-pinene, 1-hexanol, 3Z-hexenyl acetate. Electroantennograms of responses to paired mixtures of odours showed that there was considerable variation in receptor tuning across the receptor field between individuals. Data from some moth antennae showed no additivity, which indicated a restricted receptor profile. Results from other moth antennae to the same odour mixtures showed a range of partial additivity. This indicated that a wider array of receptor types w...

1783011160

Sexual dimorphisms in adult human neural, mesoderm‐derived, and neural crest‐derived stem cells

FEBS Letters, 2019

Sexual dimorphisms contribute, at least in part, to the severity and occurrence of a broad range of neurodegenerative, cardiovascular, and bone disorders. In addition to hormonal factors, increasing evidence suggests that stem cell-intrinsic mechanisms account for sex-specific differences in human physiology and pathology. Here, we discuss sex-related intrinsic mechanisms in adult stem cell populations, namely mesoderm-derived stem cells, neural stem cells (NSCs), and neural crest-derived stem cells (NCSCs), and their implications for stem cell differentiation and regeneration. We particularly focus on sex-specific differences in stem cell-mediated bone regeneration, in neuronal development, and in NSC-mediated neuroprotection. Moreover, we review our own re...

1783011160

Nonlinear thermal torsional post-buckling of carbon nanotube-reinforced composite cylindrical shell with piezoelectric actuator layers surrounded by elastic medium

Thin-Walled Structures, 2018

Abstract The paper focuses on thermal torsional post buckling of functionally graded carbon nanotube reinforced composite cylindrical shells with sur-bonding piezoelectric layers and embedded in an elastic medium. The distribution of reinforcements through the thickness of the shells is considered to be uniform and functionally graded. The basic equations using geometrically nonlinearity in von Karman-Donnell sense within the classical thin shell theory are established. The torsional post-buckling behavior of the piezoelectric functionally graded carbon nanotubes reinforced composite (FG-CNTRC) shells is analyzed with using the Airy's stress function and the Galerkin's method, in which a three-term approximate solution of the deflection of the shell is assum...

1783011159

A comparison of sieving and oil flotation methods for quantitative assessment of mite populations in grain

Journal of Stored Products Research, 1985

Separate populations of two species, Acarus siro L. and Glycyphagus destructor (Schrank), were used to inoculate grain with a known number of mites. Regardless of differences in species and original levels of infestation, recovery by oil flotation was never less than 75%, whereas that by sieving never exceeded 43% of true mite population. Moreover, flotation extraction from the sieved wheat recovered up to 60% of the population not extracted by the sieving technique. Sieving efficiency was also shown to be strongly biased by species differences, whereas flotation extraction varied little between the two species at a fixed density. Thus, sieving grossly underestimated the true level of infestation and was inconsistent and unreliable for quantitative estimatio...

1783011159

Children's task and ego goal profiles in sport

Brit J of Edu Psychol, 1994

The purpose of this study was to examine the combined effects of task and ego goal orientations on children's sport motivation. Participants were 115 boys and 116 girls (mean age = 11.12 yrs). Unlike previous research, where the correlates of the two orientations have been examined separately, this study examined the motivational consequences of different task and ego combinations. Four groups were created based on mean splits on the task and ego scales of the Task and Ego Orientation in Sport Questionnaire. These were low task/low ego, low task/high ego, high task/low ego, and high task/high ego. The hi/hi group emerged as the most motivated and the lo/lo group least motivated in measures of sport enjoyment and perceived sport competence. The lo/lo group, m...

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A review of the genusElophilaHübner, 1822 in China (Lepidoptera: Crambidae: Acentropinae)

Aquatic Insects, 2010

Fifteen species of the genus Elophila Hübner are recognised from China, including two new species described herein, namely E. radiospinula and E. nuda. The species E. melagynalis (Agassiz, 1978 Agassiz, D. 1978. ‘Five Introduced Species, Including one new to Science, of China Mark Moths (Lepidoptera: Pyralidae) new to Britain’. Entomologist's Gazette, 29: 117–127. [Google Scholar]) from Fujian Province was a misidentification of Thysanoidma octalis Hampson, 1891 and its record in China is abolished. The species E. manilensis (Hampson, 1917 Hampson, G. F. 1917. ‘Descriptions of new Pyralidae of the Subfamilies Hydrocampinae, Scoparianae, and etc’. The Annals and Magazine of Natural History, 8: 361–376. 457–473; (8) 20, 201–216, 265–282[Tayl...

1783011159

The Effect of Intraventricular Trajectory on Brain Shift in Deep Brain Stimulation

Stereotact Funct Neurosurg, 2011

Background: Brain shift during deep brain stimulation (DBS) surgery may compromise target localization. Loss of cerebrospinal fluid is believed to be the underlying mechanism, thus an intraventricular trajectory during DBS surgery may be associated with increased shift, in addition to other complications, such as intraventricular hemorrhage. Objective: We set out to assess the effect of traversing the lateral ventricle on brain shift during DBS surgery. Methods: We performed a retrospective review of 65 pre- and postoperative MR images of patients who underwent bilateral subthalamic nucleus deep brain stimulator placement to treat advanced Parkinson’s disease. Patients were separated into two groups:...

1783011158

Carboxymethylated Dextran-Coated Magnetic Iron Oxide Nanoparticles for Regenerable Bioseparation

j nanosci nanotechnol, 2011

Carboxymethylated dextran (CMD)-coated magnetic iron oxide nanoparticles (MNPs) were synthesized using a co-precipitation method. Compared to neutral dextran coated MNPs, the CMD coating provides good dispersity and colloidal stability to the CMD-MNPs. In particular, the carboxyl groups on the CMD can be readily activated for covalent attachment of antibody molecules. The superparamagnetic property of the antibody-covered CMD-MNPs enables the captured antigen to be separated from the sample solution and CMD coating significantly reduces the nonspecific binding of the nanoparticles. Regeneration of the anti-BSA antibody-covered CMD-MNPs with NaOH does not significantly decrease the antibody activity, and the repeated magnetic separation and washing steps caus...

1783011158

Astigmatic axis and amblyopia in childhood

Acta Ophthalmologica Scandinavica, 2003

This study is part of a larger project whose aim is to evaluate the relationship between refractive errors and amblyopia. In an earlier study, we showed that there is a substantial increase in the prevalence of amblyopia among children with oblique astigmatism. To further evaluate this relationship, we examined children with astigmatisms of 1 dioptre or more and varying directions of the astigmatic axes.Two groups of astigmatic children, with oblique and orthogonal astigmatism, respectively, were selected for the study at 1 year of age via a general health screening programme. The most emmetropic axis was identified in each child and used in the study. Visual acuity (VA) was tested when the children were between 4 and 4.5 years of age. The presence of amblyo...

1783011158

Corn Earworm, Helicoverpa zea (Lepidoptera: Noctuidae) and Other Insect Associated Resistance in the Maize Inbred Tex6

ec, 2002

A 2-yr field and laboratory study investigated insect resistance of the maize, Zea mays L., inbred Tex6, which has previously demonstrated resistance to Aspergillus ear rot and aflatoxin production, relative to susceptible inbred B73. Field studies indicated significantly greater resistance to insect feeding of V4-V8 growth stage Tex6 plants compared with B73 plants in both years, primarily to flea beetles (Chaetonema spp.). Field studies of natural (1999) and artificial (2000) infestations of corn earworms, Helicoverpa zea (Boddie), indicated much lower levels of kernel damage at milk stage (approximately three-fold) and smaller surviving larvae (approximately three-fold) in Tex6 compared with B73 ears. At harvest similar trends in reduction of numbers of d...

1783011158

Romancing the Tome: The Seduction of Intertext in Doubrovsky's "Un Amour de soi"

SubStance, 1993

THE LOVER IN BARTHES OCCUPIES AN IMPOSSIBLE POSITION with respect to discourse. An obsessive sign-maker, he or she is a locus of meaning, yet the experience of the Other as adorable, as emitter of fascination confirms the lover as extraneous, de trop, radically estranged from the loved one and from the discourse the lover himself or herself would manufacture. No in-between is allowed the lover, no comfortable resting point on the fence, as it were, between signifier and signified: he or she simultaneously outruns and is preceded by the possibilities of language. Le rapt we learn in Fragments d'un discours amoureux, (pur moment hypnotique) a lieu avant le discours et derriere le proscenium de la conscience.. (110). Yet seductive gesture by the lover reaches o...

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Primary stabbing headache in children and adolescents

Develop Med Child Neuro, 2019

Aim To examine the characteristics of primary stabbing headache (PSH) in typically developing children and adolescents. Method In this prospective non-interventional hospital-based study, we examined 42 eligible individuals (24 females, 18 males; 26 white; mean age 12y 1mo, range 6y–16y 1mo) with spontaneous transient stabs. A headache focused history and/or a headache diary was obtained from each patient. All patients had normal neurological examination. Diagnosis of primary headache was based on the International Classification of Headache Disorders, Third Edition (ICHD-3) beta version. Results Duration of stabs ranged from a few seconds to up to 10 minutes. Stabs were located in a variety of sites on the cranium but mostly in the extra-trigeminal region...

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A Critical Review of Cephalexin and Cefadroxil for the Treatment of Acute Uncomplicated Lower Urinary Tract Infection in the Era of “Bad Bugs, Few Drugs”

International Journal of Antimicrobial Agents, 2020

Abstract First-generation oral cephalosporins (cephalexin and cefadroxil) have traditionally been considered second-line treatment options for uncomplicated lower urinary tract infections (uLUTIs). However, in the current age of “bad bugs, few drugs”, where there are increasingly limited oral options against resistant Enterobacteriaceae, there is an urgent need to rethink how best to utilize the available antibiotic armamentarium. This review examines the historical clinical trials and experimental studies of cephalexin and cefadroxil, particularly through the modern lens of pharmacokinetics/pharmacodynamics (PK/PD), to better appreciate the efficacy of these drugs in uLUTIs. Furthermore, newer cefazolin-cephalexin surrogate testing, as recommended...

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Electrolytic Reduction of Nitro Compounds in Concentrated Aqueous Salt Solutions

Trans. Electrochem. Soc., 1935

The use of redox flow batteries (RFBs) has become popular for preserving renewable energy. For widespread commercialization, the appropriate selection of redox-active species and ion exchange membranes (IEM) is essential. Herein, we synthesized a robust PVA-Silica (PVA-SiO2) composite membrane and demonstrated its essential use in an aqueous hybrid RFB. A proton-conducting, chemically and physically stable membrane was created by combining the traditional hydrophilicity of PVA with well-defined interconnecting ion-conducting channels produced by uniformly distributed silica particles. We believe that thermal crosslinking ensured substantial dimensional and chemical durability, whereas silica permitted good ionic conductivity. The utility of the membrane was ...

1783011158

Effect of Sweetpotato Genotype, Storage Time and Production Site on Feeding and Oviposition Behavior of the Sweetpotato Weevil, Cylas formicarius (Coleoptera: Apoinidae)

The Florida Entomologist, 2001

The effect of sweetpotato genotype, storage time and production site on Cylas formicarius (Fab.) feeding and oviposition was investigated. Sweetpotato genotype had a significant effect on feeding and oviposition rates in both no-choice and choice arenas. Beauregard and Centennial were uniformly susceptible across all age groups. W-250 had the least number of feeding punctures and eggs at 7 and 25 days after harvest. At 85 days after harvest, W-244 had the least number of feeding punctures and eggs, while W-250 was not significantly different from Beauregard and Centennial. Roots of the same genotype grown in different locations differed in the number of feeding punctures and eggs. These results suggest that antixenosis is responsible for at least part of the...

1783011157

Innovative two-stage anaerobic process for effective codigestion of cheese whey and cattle manure

Bioresource Technology, 2013

The valorisation of agroindustrial waste through anaerobic digestion represents a significant opportunity for refuse treatment and renewable energy production. This study aimed to improve the codigestion of cheese whey (CW) and cattle manure (CM) by an innovative two-stage process, based on concentric acidogenic and methanogenic phases, designed for enhancing performance and reducing footprint. The optimum CW to CM ratio was evaluated under batch conditions. Thereafter, codigestion was implemented under continuous-flow conditions comparing one- and two-stage processes. The results demonstrated that the addition of CM in codigestion with CW greatly improved the anaerobic process. The highest methane yield was obtained co-treating the two substrates at equal r...

1783011157

Perfectionism and social desirability: Students report increased perfectionism to create a positive impression

Personality and Individual Differences, 2013

Because previous studies examining correlations between perfectionism and social desirability produced inconclusive findings, this study used an experimental approach examining the perceived social desirability of perfectionism. 117 university students were randomly assigned to three conditions (fake-good, standard, and fake-bad instructions) and then completed measures of self-oriented, other-oriented, and socially prescribed perfectionism. Results showed that all three forms of perfectionism were perceived as socially desirable. Self-oriented perfectionism showed a strong linear trend across the conditions: Students reported significantly higher self-oriented perfectionism in the fake-good condition, and significantly lower self-oriented perfectionism in t...

1783011157

Estimation of the thermophysical properties of date palm fibers/gypsum composite for use as insulating materials in building

Energy and Buildings, 2017

Abstract This work aims to develop a new composite material to improve the thermophysical properties and the lightness of gypsum plaster made with date palm fibers for the purpose of reducing the building energy consumption. This composite material is intended to be used in walls or false ceilings. Date palm fibers- gypsum boards could be used instead of plaster boards as thermal insulators in buildings. By varying the mass fraction of date palm fibers (from 0 to 20%), an experimental investigation of the thermo physical proprieties of gypsum reinforced with date palm fibers was mainly performed using the periodical and flash methods which were coupled to an inverse technique. The experimental results of thermal conductivity showed a good agreement with the ...

1783011157

The use of a biodegradable chelator for enhanced phytoextraction of heavy metals by Festuca arundinacea from municipal solid waste compost and associated heavy metal leaching

Bioresource Technology, 2013

In a column experiment with horizontal permeable barriers, the effects of a biodegradable chelator-nitrilotriacetic acid (NTA) on the uptake of heavy metals from municipal solid waste (MSW) compost by Festuca arundinacea and metal leaching were investigated. The use of NTA was effective in increasing Cu, Pb, and Zn uptakes in shoots of two crops of F. arundinacea. In columns with barriers and treated with 20 mmol NTA per kg MSW compost, metal uptakes by the first and second crop of F. arundinacea were, respectively, 3.8 and 4.0 times for Pb, and 1.8 and 1.7 times for Zn greater with the added NTA than without it. Though NTA application mobilized metals, it caused only slight leaching of metals from MSW compost. Permeable barriers positioned between compost a...

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