[go: up one dir, main page]

ZW11880A1 - Pyrimidine compounds processes for their preparation pharmaceutical preparations containing these compounds and their use in therapeutics - Google Patents

Pyrimidine compounds processes for their preparation pharmaceutical preparations containing these compounds and their use in therapeutics

Info

Publication number
ZW11880A1
ZW11880A1 ZW118/80A ZW11880A ZW11880A1 ZW 11880 A1 ZW11880 A1 ZW 11880A1 ZW 118/80 A ZW118/80 A ZW 118/80A ZW 11880 A ZW11880 A ZW 11880A ZW 11880 A1 ZW11880 A1 ZW 11880A1
Authority
ZW
Zimbabwe
Prior art keywords
compounds
therapeutics
pharmaceutical preparations
preparations containing
processes
Prior art date
Application number
ZW118/80A
Other languages
English (en)
Inventor
Adrian Marxer
Kurt Eichenberger
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZW11880A1 publication Critical patent/ZW11880A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZW118/80A 1979-05-18 1980-05-16 Pyrimidine compounds processes for their preparation pharmaceutical preparations containing these compounds and their use in therapeutics ZW11880A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH466979 1979-05-18

Publications (1)

Publication Number Publication Date
ZW11880A1 true ZW11880A1 (en) 1980-12-17

Family

ID=4280399

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW118/80A ZW11880A1 (en) 1979-05-18 1980-05-16 Pyrimidine compounds processes for their preparation pharmaceutical preparations containing these compounds and their use in therapeutics

Country Status (21)

Country Link
EP (1) EP0019811A1 (sv)
JP (1) JPS55154971A (sv)
KR (1) KR830002757A (sv)
AR (1) AR228256A1 (sv)
AU (1) AU5848480A (sv)
DD (1) DD150609A5 (sv)
DK (1) DK214480A (sv)
ES (1) ES8104279A1 (sv)
FI (1) FI801600A7 (sv)
GB (1) GB2052487B (sv)
GR (1) GR68453B (sv)
IE (1) IE49803B1 (sv)
IL (1) IL60086A (sv)
MA (1) MA18829A1 (sv)
NO (1) NO801469L (sv)
NZ (1) NZ193730A (sv)
OA (1) OA06533A (sv)
PL (1) PL224313A1 (sv)
PT (1) PT71251A (sv)
ZA (1) ZA802909B (sv)
ZW (1) ZW11880A1 (sv)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507146A (en) * 1982-12-28 1985-03-26 Ciba-Geigy Corporation 2,4-Diamino-6-halo-5-trifluoromethylpyrimidines having herbicidal activity
DE3829469A1 (de) * 1988-08-31 1990-03-01 Bayer Ag Verfahren zur herstellung von substituierten n-azinyl-n'-sulfonyl-isothioharnstoffen und n-azinyl-iminodithiokohlensaeure-s,s-diester als zwischenprodukte zu ihrer herstellung
AU9302298A (en) * 1997-09-03 1999-03-22 Eli Lilly And Company Pyrimidine derivatives
ES2242771T5 (es) 2000-09-15 2011-10-14 Vertex Pharmaceuticals Incorporated Compuestos de pirazol útiles como inhibidores de proteína quinasas.
US6660731B2 (en) 2000-09-15 2003-12-09 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
US7473691B2 (en) 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
CN102250071A (zh) 2000-12-21 2011-11-23 沃泰克斯药物股份有限公司 可用作蛋白激酶抑制剂的吡唑化合物
HUP0401858A3 (en) * 2001-01-31 2009-06-29 Lundbeck & Co As H Gal3 receptor antagonist pyrimidine and indolone-derivatives and their use for preparation of pharmaceutical compositions suitable for the treatment of depression and/or anxiety
AU2003223049A1 (en) 2002-03-13 2003-09-22 Euro-Celtique S.A. Aryl substituted pyrimidines and the use thereof
ES2290436T3 (es) * 2002-03-15 2008-02-16 Ciba Specialty Chemicals Holding Inc. Uso de 4-aminopiridinas para el tratamiento antimicrobiano de superficies.
AU2003218215A1 (en) 2002-03-15 2003-09-29 Vertex Pharmaceuticals, Inc. Azolylaminoazines as inhibitors of protein kinases
MY141867A (en) 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
AU2003257078B2 (en) 2002-08-02 2010-04-01 Vertex Pharmaceuticals Incorporated Pyrazole compositions useful as inhibitors of GSK-3
WO2004072029A2 (en) 2003-02-06 2004-08-26 Vertex Pharmaceuticals Incorporated Pyrazolopyridazines useful as inhibitors of protein kinases
US7737151B2 (en) 2005-08-18 2010-06-15 Vertex Pharmaceuticals Incorporated Pyrazine kinase inhibitors
AR056763A1 (es) 2005-11-03 2007-10-24 Vertex Pharma Aminopirimidinas sustituidas con tiazol o pirazol,utiles como agentes anticancer y composiciones farmaceuticas que las contienen.
WO2008057940A1 (en) 2006-11-02 2008-05-15 Vertex Pharmaceuticals Incorporated Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases
CA2673353A1 (en) 2006-12-19 2008-06-26 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as inhibitors of protein kinases
JP2010520887A (ja) 2007-03-09 2010-06-17 バーテックス ファーマシューティカルズ インコーポレイテッド 蛋白キナーゼの阻害剤として有用なアミノピリジン
JP5393489B2 (ja) 2007-03-09 2014-01-22 バーテックス ファーマシューティカルズ インコーポレイテッド 蛋白キナーゼの阻害剤として有用なアミノピリミジン
EP2134707B1 (en) 2007-03-09 2013-09-11 Vertex Pharmaceuticals, Inc. Aminopyrimidines useful as inhibitors of protein kinases
MX2009011059A (es) 2007-04-13 2009-11-26 Vertex Pharma Aminopirimidinas utiles como inhibidores de cinasas.
NZ580884A (en) 2007-05-02 2012-02-24 Vertex Pharma Thiazoles and pyrazoles useful as kinase inhibitors
AU2008247594A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Aminopyrimidines useful as kinase inhibitors
AR067762A1 (es) 2007-07-31 2009-10-21 Vertex Pharma Proceso para preparar 5-fluoro-1h-pirazolo (3,4-b) piridin-3-amina y derivados de la misma
WO2010027921A1 (en) 2008-09-03 2010-03-11 Vertex Pharmaceuticals Incorporated Co-crystals and pharmaceutical formulations comprising the same
SG172060A1 (en) * 2008-12-09 2011-07-28 Gilead Sciences Inc Modulators of toll-like receptors
KR102328682B1 (ko) * 2018-08-27 2021-11-18 주식회사 대웅제약 신규한 헤테로사이클릭아민 유도체 및 이를 포함하는 약학 조성물
EP4243826A1 (en) * 2020-11-12 2023-09-20 3Z Ehf Novel treatments of attention deficit/hyperactivity disorder

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754832A (fr) * 1969-08-14 1971-02-15 Beecham Group Ltd Iminazolines

Also Published As

Publication number Publication date
AU5848480A (en) 1980-11-20
IL60086A (en) 1984-03-30
JPS55154971A (en) 1980-12-02
FI801600A7 (sv) 1981-01-01
IE801023L (en) 1980-11-18
GR68453B (sv) 1981-12-30
KR830002757A (ko) 1983-05-30
NO801469L (no) 1980-11-19
MA18829A1 (fr) 1980-12-31
NZ193730A (en) 1982-12-21
IL60086A0 (en) 1980-07-31
AR228256A1 (es) 1983-02-15
ZA802909B (en) 1981-05-27
GB2052487B (en) 1983-05-11
IE49803B1 (en) 1985-12-25
GB2052487A (en) 1981-01-28
DK214480A (da) 1980-11-19
PL224313A1 (sv) 1981-02-13
DD150609A5 (de) 1981-09-09
EP0019811A1 (de) 1980-12-10
OA06533A (fr) 1981-07-31
PT71251A (en) 1980-06-01
ES491514A0 (es) 1981-04-16
ES8104279A1 (es) 1981-04-16

Similar Documents

Publication Publication Date Title
ZW11880A1 (en) Pyrimidine compounds processes for their preparation pharmaceutical preparations containing these compounds and their use in therapeutics
DE3067252D1 (en) Cyclopeptides and pharmaceutical preparations thereof, process for their preparation and their use
AU525046B2 (en) Improvements in and relating to pharmaceutical preparations in solid unit dosage form
ZA803567B (en) Pharmaceutical preparations
MY8700186A (en) 3-aminopropoxyaryl derivatives their preparation and pharmaceutical compositions containing them
PH16228A (en) Triazolo pyridazine derivatives,pharmaceutical composition containing the same and their use
DE3062310D1 (en) Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them
GB2095668B (en) Acylquinolinone derivatives process for their manufacture pharmaceutical preparations containing them and their use
GB2060633B (en) Isocyanuric acid derivatives preparation and pharmaceutical use thereof
ZA803539B (en) Alkoxybenzylrimidines method for their preparation formulation thereof and their use in medicine
IL59665A0 (en) Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions
JPS5328133A (en) Novel compound having lipidddepleting activity in blood*process for preparation thereof and pharmaceutical composition containing these
ZA80922B (en) Pyrazole derivatives pharmaceutical formulations containing these derivatives and processes for their preparation
IL60325A0 (en) Novel quinazoline derivatives and pharmaceutical preparations containing them
ZA803535B (en) Novel quinazoline derivatives and pharmaceutical preparations
IL59664A0 (en) Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions
DE2862102D1 (en) Pyrimido (4,5-c) pyridazines, their use in pharmaceutical preparations, and process for their preparation
PH16060A (en) Pyrimidine derivatives and pharmaceutical preparation thereof
ZW15180A1 (en) Aminothiadiazolyl compounds processes for the manufacture thereof and pharmaceutical preparations containing such compounds and the use thereof
ZW8980A1 (en) Improvements in conditioning preparations for human use
ZA793336B (en) Novel phenylpiperidine derivatives,processes for their preparation,pharmaceutical preparations containing these derivatives and their use
DE3066533D1 (en) Optically active cephalosporin analogs, process for their preparation and their use in the preparation of pharmaceutical compositions
DE2861167D1 (en) 2-amino-thiazoline derivatives, their preparation and their use in pharmaceutical preparations
MY8500403A (en) Ethsanolamine compounds, prolesses for their preparation, pharmaceutical preparations containing them and their medicinal use
GB2013671B (en) Azathianaphthalene derivatives process for their manufactue pharmaceutical preparations containing them and their use