[go: up one dir, main page]

ZA9811940B - Novel erythromycin derivatives. - Google Patents

Novel erythromycin derivatives.

Info

Publication number
ZA9811940B
ZA9811940B ZA9811940A ZA9811940A ZA9811940B ZA 9811940 B ZA9811940 B ZA 9811940B ZA 9811940 A ZA9811940 A ZA 9811940A ZA 9811940 A ZA9811940 A ZA 9811940A ZA 9811940 B ZA9811940 B ZA 9811940B
Authority
ZA
South Africa
Prior art keywords
erythromycin derivatives
novel erythromycin
novel
derivatives
erythromycin
Prior art date
Application number
ZA9811940A
Other languages
English (en)
Inventor
Yong-Jin Wu
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA9811940B publication Critical patent/ZA9811940B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA9811940A 1998-01-02 1998-12-30 Novel erythromycin derivatives. ZA9811940B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7035898P 1998-01-02 1998-01-02

Publications (1)

Publication Number Publication Date
ZA9811940B true ZA9811940B (en) 2000-06-30

Family

ID=22094819

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9811940A ZA9811940B (en) 1998-01-02 1998-12-30 Novel erythromycin derivatives.

Country Status (36)

Country Link
US (1) US6825171B2 (sk)
EP (2) EP1642901B1 (sk)
JP (1) JP2002500231A (sk)
KR (1) KR20010033822A (sk)
CN (1) CN1285841A (sk)
AP (1) AP1060A (sk)
AR (5) AR012764A1 (sk)
AT (1) ATE377018T1 (sk)
AU (1) AU759019B2 (sk)
BG (1) BG104640A (sk)
BR (1) BR9812992A (sk)
CA (1) CA2317131C (sk)
CO (1) CO4970773A1 (sk)
CZ (1) CZ20002456A3 (sk)
DE (1) DE69838651T9 (sk)
DZ (1) DZ2699A1 (sk)
EA (1) EA200000600A1 (sk)
ES (1) ES2294641T3 (sk)
GT (1) GT199800207A (sk)
HR (1) HRP20000444A2 (sk)
HU (1) HUP0100566A3 (sk)
IL (1) IL136721A0 (sk)
IS (1) IS5527A (sk)
MA (1) MA26588A1 (sk)
NO (1) NO20003346L (sk)
NZ (1) NZ504987A (sk)
OA (1) OA11440A (sk)
PA (1) PA8465901A1 (sk)
PE (1) PE20000119A1 (sk)
PL (1) PL341647A1 (sk)
SK (1) SK9772000A3 (sk)
TN (1) TNSN98236A1 (sk)
UY (2) UY25331A1 (sk)
WO (1) WO1999035157A1 (sk)
YU (1) YU40900A (sk)
ZA (1) ZA9811940B (sk)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
GB9814006D0 (en) 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
ES2273964T3 (es) 1998-12-10 2007-05-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
ATE256694T1 (de) 1999-01-27 2004-01-15 Pfizer Prod Inc Ketolid-antibiotika
EP1754700A3 (en) 1999-01-27 2007-05-09 Kosan Biosciences, Inc. Synthesis of oligoketides
MXPA01010521A (es) * 1999-04-16 2003-08-19 Johnson & Johnson Antibacteriales de cetolidos.
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
EP1171446B1 (en) 1999-04-16 2006-09-20 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
WO2001060833A2 (en) 2000-02-18 2001-08-23 Kosan Biosciences, Inc. Motilide compounds
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
US6472372B1 (en) 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
AU2002316550A1 (en) 2001-07-03 2003-01-21 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
CA2460947A1 (en) 2001-09-17 2003-03-27 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
CN1585775A (zh) 2001-12-05 2005-02-23 奥索-麦克尼尔药品公司 可用作抗菌药的红霉素的6-o-酰基酮内酯衍生物
US6825172B2 (en) 2002-05-31 2004-11-30 Janssen Pharmaceutica, Nv 3-descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents
US7163924B2 (en) 2003-04-25 2007-01-16 Chiron Corporation Ketolide derivatives
CN101120011A (zh) 2004-12-21 2008-02-06 辉瑞产品公司 大环内酯
DE602007006663D1 (de) 2006-06-12 2010-07-01 Univ Ramot Verfahren zur behandlung von krebs
EA201500699A1 (ru) 2012-12-24 2015-12-30 Рамот Эт Тель-Авив Юниверсити Лтд. Агенты для лечения генетических заболеваний, возникающих в результате нонсенс-мутаций, и способы идентификации этих агентов

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US156027A (en) * 1874-10-20 Improvement in loom-shuttles
US61857A (en) * 1867-02-05 Improvement in top-drivers or spinners
US61856A (en) * 1867-02-05 Enos s
US77302A (en) * 1868-04-28 mat son
US100518A (en) * 1870-03-08 Roland s
US4331803A (en) * 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
SI8110592A8 (en) 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
AU1142383A (en) 1982-04-26 1983-11-03 Shakas, P.V. Infant transitional sensory system
US4474768A (en) 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4998097A (en) 1983-07-11 1991-03-05 Square D Company Mechanically operated pressure switch having solid state components
JPS61103890A (ja) * 1984-10-26 1986-05-22 Taisho Pharmaceut Co Ltd 6−0−メチルエリスロマイシンa誘導体
US4585759A (en) * 1985-01-22 1986-04-29 Pfizer Inc. Antibacterial derivatives of a neutral macrolide
JPS61229895A (ja) * 1985-04-03 1986-10-14 Nippon Zeon Co Ltd 保護化デス−n−メチルエリスロマイシン誘導体
ES8800986A1 (es) 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
US4672056A (en) * 1985-11-12 1987-06-09 Abbott Laboratories Erythromycin A derivatives and method of use
JPH0633312B2 (ja) 1986-05-02 1994-05-02 大正製薬株式会社 14−ハイドロキシエリスロマイシン誘導体およびその製造方法
DE3860503D1 (de) * 1987-09-03 1990-10-04 Pliva Pharm & Chem Works 10-dihydro-10-deoxo-11-azaerythronolid-a-verbindungen,verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung in arzneimitteln und in deren herstellung.
GB8726730D0 (en) 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
GB8815967D0 (en) 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
US4934897A (en) 1989-02-23 1990-06-19 J. I. Case Company Pipe-moving apparatus
US5141926A (en) 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
WO1993013663A1 (en) 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
US6060234A (en) * 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
JP3286941B2 (ja) * 1991-07-09 2002-05-27 株式会社日立製作所 ダイヤモンド研削砥石のツルーイング法
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
FR2691464B1 (fr) 1992-05-21 1995-06-02 Roussel Uclaf Nouveaux dérivés de la 1-oxa 6-azacyclopentadécane 13,15-dione, leur procédé de préparation et leur application comme médicaments.
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
US6066721A (en) * 1995-07-06 2000-05-23 Stanford University Method to produce novel polyketides
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
US5486697A (en) 1994-11-14 1996-01-23 California Institute Of Technology Array of micro-machined mass energy micro-filters for charged particles
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) * 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5801032A (en) 1995-08-03 1998-09-01 Abbott Laboratories Vectors and process for producing high purity 6,12-dideoxyerythromycin A by fermentation
WO1997008266A1 (en) 1995-08-22 1997-03-06 Mobil Oil Corporation Visbreaking process using plastics as co-feed
JP2000500133A (ja) 1995-11-08 2000-01-11 アボツト・ラボラトリーズ 三環式エリスロマイシン誘導体
US6077943A (en) * 1996-03-01 2000-06-20 Takeda Chemical Industries, Ltd. Method of producing erythromycin derivative
US5719272A (en) * 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
DK0909327T3 (da) 1996-07-05 2005-09-26 Biotica Tech Ltd Erythromyciner og fremgangsmåder til deres fremstilling
US6271255B1 (en) * 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
ATE299508T1 (de) * 1996-09-04 2005-07-15 Abbott Lab 6-o-substituierte ketoliden mit antibakteriellen wirkung
FR2754821B1 (fr) 1996-10-23 2003-04-04 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
NL1006540C2 (nl) 1997-07-10 1999-01-15 Skf Ind Trading & Dev Elektrische actuator met regelsensor, alsmede schijfrem omvattende een dergelijke actuator.
US6367697B1 (en) 1997-08-28 2002-04-09 Supersensor (Proprietary) Limited Reader arrangement for an electronic identification system having a plurality of reader heads for energizing transponders
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
PT941998E (pt) * 1998-03-03 2004-12-31 Pfizer Prod Inc Antibioticos macrolidos do tipo 3,6-cetal
US5975370A (en) * 1998-03-16 1999-11-02 Owens-Illinois Closure Inc. Tamper-evident plunger-hold-down attachment for pump dispenser
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
ATE256694T1 (de) 1999-01-27 2004-01-15 Pfizer Prod Inc Ketolid-antibiotika
US6316197B1 (en) 1999-02-05 2001-11-13 The United States Of America As Represented By The Secretary Of The Army Method of diagnosing of exposure to toxic agents by measuring distinct pattern in the levels of expression of specific genes
EP1171446B1 (en) * 1999-04-16 2006-09-20 Kosan Biosciences, Inc. Macrolide antiinfective agents
MXPA01010521A (es) * 1999-04-16 2003-08-19 Johnson & Johnson Antibacteriales de cetolidos.
US20020077302A1 (en) 1999-04-23 2002-06-20 Yong-Jin Wu Tricyclic erythromycin derivatives
US20020061857A1 (en) 1999-04-23 2002-05-23 Yong-Jin Wu 9-amino-3-oxo erythromycin derivatives
IL145739A0 (en) 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
EP1101769A3 (en) * 1999-11-18 2001-10-24 Pfizer Products Inc. Nitrogen containing erythromycin derivatives
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
JP2005050903A (ja) 2003-07-30 2005-02-24 Toshiba Corp 半導体装置およびその製造方法

Also Published As

Publication number Publication date
IS5527A (is) 2000-06-09
AR019788A2 (es) 2002-03-13
DE69838651D1 (de) 2007-12-13
WO1999035157A1 (en) 1999-07-15
AP9801421A0 (en) 1998-12-31
EP1044208A1 (en) 2000-10-18
PA8465901A1 (es) 2000-09-29
BG104640A (en) 2001-09-28
HRP20000444A2 (en) 2001-04-30
HUP0100566A3 (en) 2003-07-28
YU40900A (sh) 2003-01-31
AU759019B2 (en) 2003-04-03
NZ504987A (en) 2002-11-26
AR012764A1 (es) 2000-11-08
EP1642901B1 (en) 2007-10-31
WO1999035157B1 (en) 1999-10-14
EA200000600A1 (ru) 2001-02-26
DE69838651T9 (de) 2008-06-12
PE20000119A1 (es) 2000-02-17
CO4970773A1 (es) 2000-11-07
NO20003346D0 (no) 2000-06-27
UY25587A1 (es) 1999-09-27
SK9772000A3 (en) 2002-09-10
EP1642901A1 (en) 2006-04-05
AR019790A2 (es) 2002-03-13
PL341647A1 (en) 2001-04-23
MA26588A1 (fr) 2004-12-20
US6825171B2 (en) 2004-11-30
AP1060A (en) 2002-04-23
US20040067897A1 (en) 2004-04-08
IL136721A0 (en) 2001-06-14
NO20003346L (no) 2000-08-29
HUP0100566A2 (hu) 2001-07-30
AU1501599A (en) 1999-07-26
KR20010033822A (ko) 2001-04-25
AR019789A2 (es) 2002-03-13
ATE377018T1 (de) 2007-11-15
AR020016A2 (es) 2002-03-27
DZ2699A1 (fr) 2003-03-29
CZ20002456A3 (cs) 2001-09-12
GT199800207A (es) 2000-06-22
DE69838651T2 (de) 2008-03-06
CN1285841A (zh) 2001-02-28
UY25331A1 (es) 2000-12-29
BR9812992A (pt) 2000-10-17
CA2317131C (en) 2004-11-02
JP2002500231A (ja) 2002-01-08
ES2294641T3 (es) 2008-04-01
CA2317131A1 (en) 1999-07-15
TNSN98236A1 (fr) 2005-03-15
OA11440A (en) 2004-04-28

Similar Documents

Publication Publication Date Title
ZA9811940B (en) Novel erythromycin derivatives.
ZA9811939B (en) Novel macrolides.
ZA99254B (en) Benzosulfone derivatives.
ZA991273B (en) Amidinophenyl derivatives.
ZA996185B (en) Sulfanylsilanes.
ZA200005136B (en) Dihydropyrimides.
ZA200000894B (en) 4-Phenyl-pyridine derivatives.
PL348333A1 (en) Macrolides
ZA985018B (en) 9-oxime erythromycin derivatives.
ZA200109595B (en) 13-methyl-erythromycin derivatives.
ZA200103289B (en) Novel macrolide antibiotics.
ZA991272B (en) Novel thiobenzamides.
ZA987688B (en) 6,9-bridged erythromycin derivatives
ZA992191B (en) Piperidine derivatives.
IL134996A0 (en) 6,11-bridged erythromycin derivatives
ZA200107346B (en) Erythromycin derivatives.
ZA992443B (en) Hydroxy-methyl-hexanones.
ZA991550B (en) Cyclohexanediole derivatives.
ZA993123B (en) Trisresorcinyltriazines.
ZA200101830B (en) Piperidine derivatives.
ZA995325B (en) Methylcyclotetradec-5-en-1-ones.
ZA982436B (en) Thiazolimine derivatives.
ZA983902B (en) Erythromycin derivatives.
MXPA01011285A (es) Derivados de tio-oxindol.
MXPA99011001A (es) Derivados de eritromicina multiciclicos.