ZA9811725B - Triazine compounds. - Google Patents

Triazine compounds.

Info

Publication number: ZA9811725B
Authority: ZA; South Africa
Prior art keywords: triazine compounds; triazine; compounds
Prior art date: 1997-12-22

Application number

ZA9811725A

Other languages

English (en)

Inventor

Brian Cox

Mark Patrick Healy

Malcolm Stuart Nobbs

Gita Punjabhai Sham

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-22

Filing date

1998-12-21

Publication date

2000-06-27

1998-12-21 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2000-06-27 Publication of ZA9811725B publication Critical patent/ZA9811725B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA9811725A 1997-12-22 1998-12-21 Triazine compounds. ZA9811725B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9726987.2A GB9726987D0 (en)	1997-12-22	1997-12-22	Compounds

Publications (1)

Publication Number	Publication Date
ZA9811725B true ZA9811725B (en)	2000-06-27

Family

ID=10823992

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9811725A ZA9811725B (en)	1997-12-22	1998-12-21	Triazine compounds.

Country Status (34)

Country	Link
US (2)	US6265405B1 (is)
EP (1)	EP1042304A1 (is)
JP (1)	JP2001526275A (is)
KR (1)	KR20010024800A (is)
CN (1)	CN1284951A (is)
AP (1)	AP2000001846A0 (is)
AR (1)	AR014146A1 (is)
AU (1)	AU753874B2 (is)
BR (1)	BR9814495A (is)
CA (1)	CA2315620A1 (is)
CO (1)	CO5011066A1 (is)
EA (1)	EA200000561A1 (is)
EE (1)	EE200000391A (is)
GB (1)	GB9726987D0 (is)
GT (1)	GT199800203A (is)
HN (1)	HN1998000193A (is)
HR (1)	HRP20000419A2 (is)
HU (1)	HUP0100611A3 (is)
ID (1)	ID25449A (is)
IL (1)	IL136867A0 (is)
IS (1)	IS5542A (is)
JO (1)	JO2065B1 (is)
MA (1)	MA26587A1 (is)
NO (1)	NO20003211L (is)
NZ (1)	NZ505254A (is)
PA (1)	PA8465101A1 (is)
PE (1)	PE20000063A1 (is)
PL (1)	PL341392A1 (is)
SK (1)	SK9592000A3 (is)
SV (1)	SV1998000151A (is)
TR (1)	TR200001970T2 (is)
WO (1)	WO1999032462A1 (is)
YU (1)	YU39600A (is)
ZA (1)	ZA9811725B (is)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0002666D0 (en)	2000-02-04	2000-03-29	Univ London	Blockade of voltage dependent sodium channels
PT1458386E (pt) *	2001-12-27	2007-06-04	Ortho Mcneil Pharm Inc	''aroilpirrole-heteroarilo e metanóis úteis para o tratamento de um distúrbio do sistema nervoso central''
EP1524981B1 (en) *	2002-07-29	2009-03-11	Glaxo Group Limited	Sustained release formulations comprising lamotrigine
JP2006515326A (ja) *	2003-01-30	2006-05-25	ダイノジェンファーマシューティカルズ，インコーポレイテッド	胃腸管障害を処置するためのナトリウムチャネルモジュレーターの使用
MY142651A (en)	2003-03-18	2010-12-15	Merck Sharp & Dohme	Biaryl substituted triazoles as sodium channel blockers
DE10332472A1 (de) *	2003-07-16	2005-02-03	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Ambroxol für die Behandlung von Tinnitus
WO2005018627A1 (en) *	2003-08-25	2005-03-03	Newron Pharmaceuticals, Spa	Alpha-aminoamide derivatives useful as anti-inflammatory agents
US20060115865A1 (en) *	2004-10-25	2006-06-01	Anlong Ouyang	Lamotrigine analogs
GB201111712D0 (en)	2011-07-08	2011-08-24	Gosforth Ct Holdings Pty Ltd	Pharmaceutical compositions
TWI651310B (zh)	2014-02-20	2019-02-21	日商日本煙草產業股份有限公司	三化合物及其醫藥用途
SG11201800698VA (en)	2015-08-17	2018-03-28	Japan Tobacco Inc	Hydroxytriazine compound and medical use thereof
ES2770143T3 (es) *	2018-02-13	2020-06-30	Fis Fabbrica Italiana Sintetici Spa	Nuevo procedimiento eficiente para la preparación de sitagliptina
CN114796146B (zh) *	2022-04-28	2023-03-28	上海奥科达医药科技股份有限公司	一种拉莫三嗪的缓释制剂及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3637688A (en)	1970-01-09	1972-01-25	American Home Prod	6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines
EP0021120B1 (en)	1979-06-01	1983-04-06	The Wellcome Foundation Limited	3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them
JPS5625169A (en)	1979-06-01	1981-03-10	Wellcome Found	Triazine derivative
EP0024351B1 (en)	1979-08-16	1984-10-31	The Wellcome Foundation Limited	Solid pharmaceutical formulation containing substitued phenyl-triazines
GB8328757D0 (en)	1983-10-27	1983-11-30	Wellcome Found	Chemical compounds
GB9012316D0 (en)	1990-06-01	1990-07-18	Wellcome Found	Pharmacologically active cns compounds
GB9012312D0 (en)	1990-06-01	1990-07-18	Wellcome Found	Pharmacologically active cns compounds
GB9012311D0 (en)	1990-06-01	1990-07-18	Wellcome Found	Pharmacologically active cns compounds
GB9203483D0 (en)	1992-02-19	1992-04-08	Wellcome Found	Anti-inflammatory compounds
DK0644763T3 (da)	1992-06-12	1997-07-28	Wellcome Found	Anvendelse af 3,5-diamino-6-(2,3-dichlorphenyl)-1,2,4-triacin-isethionat til behandlingen og forebyggelsen af afhængighed, tolerance og sensitivering af medikamenter
WO1994014780A1 (en)	1992-12-18	1994-07-07	The Wellcome Foundation Limited	Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors
US5866597A (en)	1993-03-19	1999-02-02	Glaxo Wellcome Inc.	Use of triazine compounds for the treatment of memory and learning disorders
GB9305692D0 (en)	1993-03-19	1993-05-05	Wellcome Found	Therapeutic triazine compounds and use
GB9426448D0 (en)	1994-12-30	1995-03-01	Wellcome Found	Process
FR2741879A1 (fr)	1995-12-05	1997-06-06	Esteve Labor Dr	Derives de fluorophenyl-triazines et pyrimidines, leur preparation et leur application en tant que medicament

1997
- 1997-12-22 GB GBGB9726987.2A patent/GB9726987D0/en not_active Ceased
1998
- 1998-12-18 AR ARP980106526A patent/AR014146A1/es not_active Application Discontinuation
- 1998-12-18 EA EA200000561A patent/EA200000561A1/ru unknown
- 1998-12-18 IL IL13686798A patent/IL136867A0/xx unknown
- 1998-12-18 US US09/582,058 patent/US6265405B1/en not_active Expired - Fee Related
- 1998-12-18 HR HR20000419A patent/HRP20000419A2/hr not_active Application Discontinuation
- 1998-12-18 TR TR2000/01970T patent/TR200001970T2/xx unknown
- 1998-12-18 JP JP2000525399A patent/JP2001526275A/ja active Pending
- 1998-12-18 SV SV1998000151A patent/SV1998000151A/es unknown
- 1998-12-18 EE EEP200000391A patent/EE200000391A/xx unknown
- 1998-12-18 HU HU0100611A patent/HUP0100611A3/hu unknown
- 1998-12-18 EP EP98966635A patent/EP1042304A1/en not_active Withdrawn
- 1998-12-18 CA CA002315620A patent/CA2315620A1/en not_active Abandoned
- 1998-12-18 PL PL98341392A patent/PL341392A1/xx unknown
- 1998-12-18 NZ NZ505254A patent/NZ505254A/en unknown
- 1998-12-18 AU AU24147/99A patent/AU753874B2/en not_active Ceased
- 1998-12-18 KR KR1020007006947A patent/KR20010024800A/ko not_active Withdrawn
- 1998-12-18 WO PCT/EP1998/008273 patent/WO1999032462A1/en not_active Ceased
- 1998-12-18 AP APAP/P/2000/001846A patent/AP2000001846A0/en unknown
- 1998-12-18 SK SK959-2000A patent/SK9592000A3/sk unknown
- 1998-12-18 CO CO98075403A patent/CO5011066A1/es unknown
- 1998-12-18 ID IDW20001416A patent/ID25449A/id unknown
- 1998-12-18 CN CN98813745A patent/CN1284951A/zh active Pending
- 1998-12-18 BR BR9814495-2A patent/BR9814495A/pt not_active IP Right Cessation
- 1998-12-18 YU YU39600A patent/YU39600A/sh unknown
- 1998-12-21 ZA ZA9811725A patent/ZA9811725B/xx unknown
- 1998-12-21 PE PE1998001255A patent/PE20000063A1/es not_active Application Discontinuation
- 1998-12-21 JO JO19982065A patent/JO2065B1/en active
- 1998-12-21 PA PA19988465101A patent/PA8465101A1/es unknown
- 1998-12-22 MA MA25403A patent/MA26587A1/fr unknown
- 1998-12-22 GT GT199800203A patent/GT199800203A/es unknown
1999
- 1999-12-21 HN HN1998000193A patent/HN1998000193A/es unknown
2000
- 2000-06-20 IS IS5542A patent/IS5542A/is unknown
- 2000-06-21 NO NO20003211A patent/NO20003211L/no unknown
2001
- 2001-07-06 US US09/899,198 patent/US6465461B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2315620A1 (en)	1999-07-01
HUP0100611A2 (hu)	2001-09-28
BR9814495A (pt)	2000-10-10
CN1284951A (zh)	2001-02-21
AU2414799A (en)	1999-07-12
US6265405B1 (en)	2001-07-24
SV1998000151A (es)	1999-07-05
YU39600A (sh)	2002-11-15
KR20010024800A (ko)	2001-03-26
HUP0100611A3 (en)	2003-03-28
PA8465101A1 (es)	2000-09-29
TR200001970T2 (tr)	2001-01-22
SK9592000A3 (en)	2001-03-12
GB9726987D0 (en)	1998-02-18
IL136867A0 (en)	2001-06-14
JP2001526275A (ja)	2001-12-18
NZ505254A (en)	2002-06-28
EA200000561A1 (ru)	2001-04-23
HN1998000193A (es)	2000-04-05
AU753874B2 (en)	2002-10-31
AR014146A1 (es)	2001-02-07
MA26587A1 (fr)	2004-12-20
JO2065B1 (en)	2000-05-21
US6465461B1 (en)	2002-10-15
AP2000001846A0 (en)	2000-06-30
HRP20000419A2 (en)	2000-12-31
ID25449A (id)	2000-10-05
EP1042304A1 (en)	2000-10-11
WO1999032462A1 (en)	1999-07-01
CO5011066A1 (es)	2001-02-28
PE20000063A1 (es)	2000-02-16
EE200000391A (et)	2002-02-15
NO20003211L (no)	2000-08-21
GT199800203A (es)	2000-06-14
PL341392A1 (en)	2001-04-09
NO20003211D0 (no)	2000-06-21
IS5542A (is)	2000-06-20

Publication	Publication Date	Title
ZA989767B (en)	2000-04-28	Novel compounds.
EG24814A (en)	2010-09-21	Novel compounds.
ZA97912B (en)	1997-08-05	Heterocyclic compounds.
ZA9711092B (en)	1999-07-22	Novel compounds.
ZA9810125B (en)	2000-05-05	Chemical compounds.
ZA987489B (en)	2000-02-21	Fungicidal 2-methoxybenzophenones.
ZA9811915B (en)	1999-11-05	Fungicidal compounds.
ZA9811705B (en)	1999-09-07	Oranic compounds.
ZA9711567B (en)	1998-06-24	Compounds.
DE59804842D1 (en)	2002-08-22	Aliphatische, emissionsarme, sinterfähige thermoplastische polyurethanformmassen
ZA981926B (en)	1999-09-06	Detergent--package combination.
ZA987058B (en)	2000-02-07	Substituted 4-benzoylpyrazoles.
ZA987055B (en)	2000-02-07	Substituted 4-benzoylpyrazoles.
ZA9811725B (en)	2000-06-27	Triazine compounds.
ZA979617B (en)	1998-05-21	Novel heterocyclic compounds.
ZA975861B (en)	1998-01-30	Bromotiacumicin compounds.
ZA9811758B (en)	2000-06-22	Novel compounds.
ZA9811503B (en)	2000-06-15	Novel compounds.
ZA982436B (en)	1999-09-23	Thiazolimine derivatives.
ZA989719B (en)	2000-04-26	Polymorphs.
ZA983705B (en)	1999-11-01	Pregnan-3-ol-20-ones.
ZA98868B (en)	1999-08-03	Novel compounds.
ZA987B (en)	1999-07-02	Substituted 4-benzoylpyrazoles.
ZA979404B (en)	1998-06-01	Aspirinate compounds.
ZA986752B (en)	2000-01-31	Basimino-substituted phenyl compounds.