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ZA9710832B - Obese muteins. - Google Patents

Obese muteins.

Info

Publication number
ZA9710832B
ZA9710832B ZA9710832A ZA9710832A ZA9710832B ZA 9710832 B ZA9710832 B ZA 9710832B ZA 9710832 A ZA9710832 A ZA 9710832A ZA 9710832 A ZA9710832 A ZA 9710832A ZA 9710832 B ZA9710832 B ZA 9710832B
Authority
ZA
South Africa
Prior art keywords
muteins
obese
obese muteins
Prior art date
Application number
ZA9710832A
Inventor
Rene Devos
Yves Guisez
Geert Plaetinck
Jose Van Der Heyden
Sandra Verploegen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA9710832B publication Critical patent/ZA9710832B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/5759Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA9710832A 1996-12-06 1997-12-02 Obese muteins. ZA9710832B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96119606 1996-12-06

Publications (1)

Publication Number Publication Date
ZA9710832B true ZA9710832B (en) 1998-06-08

Family

ID=8223476

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710832A ZA9710832B (en) 1996-12-06 1997-12-02 Obese muteins.

Country Status (8)

Country Link
AR (1) AR010333A1 (en)
AU (1) AU5654998A (en)
CO (1) CO4930295A1 (en)
HR (1) HRP970654A2 (en)
MA (1) MA24411A1 (en)
PE (1) PE20399A1 (en)
WO (1) WO1998024896A2 (en)
ZA (1) ZA9710832B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777388B1 (en) * 1998-08-21 2004-08-17 Clf Medical Technology Acceleration Program, Inc. Leptin-related peptides
US7208572B2 (en) 1998-08-21 2007-04-24 Albany Medical College Leptin-related peptides
US6420339B1 (en) * 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
US8227408B2 (en) 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
CA2725143A1 (en) 2008-05-21 2009-11-26 Neurotez, Inc. Methods for treating progressive cognitive disorders related to neurofibrillary tangles
WO2010054017A1 (en) 2008-11-04 2010-05-14 Nikolaos Tezapsidis Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amlyoid beta
EA032917B1 (en) 2010-09-28 2019-08-30 Амилин Фармасьютикалс, Ллк Engineered polypeptides having enhanced duration of action

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK173435B1 (en) * 1983-08-17 2000-10-23 Wellcome Found Injectable preparations and methods for potentiating the administration of a hormone to normal vertebrates or to
US6309853B1 (en) * 1994-08-17 2001-10-30 The Rockfeller University Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
WO1996023517A1 (en) * 1995-01-31 1996-08-08 Eli Lilly And Company Anti-obesity proteins
GB9509164D0 (en) * 1995-05-05 1995-06-28 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
WO1998024896A3 (en) 1998-10-01
CO4930295A1 (en) 2000-06-27
AR010333A1 (en) 2000-06-07
AU5654998A (en) 1998-06-29
WO1998024896A2 (en) 1998-06-11
HRP970654A2 (en) 1998-10-31
PE20399A1 (en) 1999-03-05
MA24411A1 (en) 1998-07-01

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