[go: up one dir, main page]

ZA9710649B - Benzopyran compounds, process for preparing them and pharmaceutical compositions containing them. - Google Patents

Benzopyran compounds, process for preparing them and pharmaceutical compositions containing them.

Info

Publication number
ZA9710649B
ZA9710649B ZA9710649A ZA9710649A ZA9710649B ZA 9710649 B ZA9710649 B ZA 9710649B ZA 9710649 A ZA9710649 A ZA 9710649A ZA 9710649 A ZA9710649 A ZA 9710649A ZA 9710649 B ZA9710649 B ZA 9710649B
Authority
ZA
South Africa
Prior art keywords
alkyl
optionally substituted
alkoxycarbonyl
preparing
pharmaceutical compositions
Prior art date
Application number
ZA9710649A
Other languages
English (en)
Inventor
Timothee Muller
Claudie Moulin
Muriel Duflos
Sylvie Robert-Piessard
Guillaume Le Baut
Alain Tonnerre
Daniel-Henri Caignard
Dominique Manechez
Pierre Renard
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA9710649B publication Critical patent/ZA9710649B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9710649A 1996-11-26 1997-11-26 Benzopyran compounds, process for preparing them and pharmaceutical compositions containing them. ZA9710649B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614470A FR2756284B1 (fr) 1996-11-26 1996-11-26 Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA9710649B true ZA9710649B (en) 1998-06-12

Family

ID=9498038

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9710649A ZA9710649B (en) 1996-11-26 1997-11-26 Benzopyran compounds, process for preparing them and pharmaceutical compositions containing them.

Country Status (19)

Country Link
US (1) US5889045A (no)
EP (1) EP0844245B1 (no)
JP (1) JPH10158260A (no)
CN (1) CN1183412A (no)
AT (1) ATE201020T1 (no)
AU (1) AU720479B2 (no)
BR (1) BR9705064A (no)
CA (1) CA2222467C (no)
DE (1) DE69704755T2 (no)
DK (1) DK0844245T3 (no)
ES (1) ES2157539T3 (no)
FR (1) FR2756284B1 (no)
GR (1) GR3036242T3 (no)
HU (1) HUP9702227A3 (no)
NO (1) NO975402L (no)
NZ (1) NZ329264A (no)
PL (1) PL323339A1 (no)
PT (1) PT844245E (no)
ZA (1) ZA9710649B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1268942A (zh) * 1997-06-27 2000-10-04 藤泽药品工业株式会社 磺酰胺化合物及其药物用途
AU2440599A (en) * 1998-02-25 1999-09-15 Shionogi & Co., Ltd. Therapeutic agent for complication of diabetes
KR100352986B1 (ko) * 2000-04-28 2002-09-18 주식회사 태평양 세라미드 유사 화합물 및 이의 제조방법, 및 이를함유하는 화장료 조성물
JP2006514666A (ja) * 2003-02-26 2006-05-11 中国科学院上海薬物研究所 ベンゾピラン系化合物、その製造方法及び用途
EP3549594A1 (en) 2005-09-16 2019-10-09 Cornell Research Foundation, Inc. Aromatic-cationic peptide for use in a method for reducing cd36 expression
EP3456707B1 (en) * 2007-11-06 2020-04-15 PTC Therapeutics, Inc. 4- (p-quinonyl)-2-hydroxybutanamide derivatives for treatment of mitochondrial diseases
PL3297625T3 (pl) 2015-05-22 2022-11-14 Sulfateq B.V. Związek do profilaktyki lub leczenia nefropatii cukrzycowej lub cukrzycowej choroby nerek
TW201831471A (zh) 2017-02-24 2018-09-01 盧森堡商艾伯維公司 囊腫纖化症跨膜傳導調節蛋白的調節劑及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE161837T1 (de) * 1990-07-25 1998-01-15 Teijin Ltd Benzopyran derivat, seine darstellung und pharmazeutische zusammensetzung, welche dieses enthält
FR2676056B1 (fr) * 1991-05-03 1993-07-16 Adir Nouveaux derives du benzopyranne leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
KR950009863B1 (ko) * 1991-05-22 1995-08-29 재단법인한국화학연구소 벤조피란 유도체와 그의 제조방법
TW244350B (no) * 1991-12-14 1995-04-01 Hoechst Ag
ZA93436B (en) * 1992-01-24 1993-08-25 Chugai Pharmaceutical Co Ltd Benzopyran derivatives
US5236935A (en) * 1992-05-21 1993-08-17 Korea Research Institute Of Chemical Technology Benzopyran derivatives and processes for the preparation thereof
US5516917A (en) * 1994-06-08 1996-05-14 G. D. Searle & Co. Leukotriene B4 antagonists
DK0707007T3 (da) * 1994-10-14 2002-03-18 Merck Patent Gmbh Amino(thio)etherderivater som CNS-aktive midler
FR2733685B1 (fr) * 1995-05-05 1997-05-30 Adir Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate

Also Published As

Publication number Publication date
JPH10158260A (ja) 1998-06-16
AU720479B2 (en) 2000-06-01
ES2157539T3 (es) 2001-08-16
ATE201020T1 (de) 2001-05-15
BR9705064A (pt) 1999-07-20
EP0844245B1 (fr) 2001-05-09
FR2756284B1 (fr) 2000-04-28
DE69704755T2 (de) 2002-02-28
CN1183412A (zh) 1998-06-03
HU9702227D0 (en) 1998-01-28
AU4538397A (en) 1998-05-28
PT844245E (pt) 2001-09-28
FR2756284A1 (fr) 1998-05-29
NO975402D0 (no) 1997-11-25
DK0844245T3 (da) 2001-06-11
GR3036242T3 (en) 2001-10-31
EP0844245A1 (fr) 1998-05-27
US5889045A (en) 1999-03-30
CA2222467A1 (fr) 1998-05-26
DE69704755D1 (de) 2001-06-13
HUP9702227A3 (en) 1999-03-01
PL323339A1 (en) 1998-06-08
CA2222467C (fr) 2002-05-28
NZ329264A (en) 1998-04-27
HUP9702227A2 (hu) 1998-12-28
NO975402L (no) 1998-05-27

Similar Documents

Publication Publication Date Title
TW339333B (en) N-substituted dioxothiazalidylbenzamide derivatives and the process for preparation thereof
ATE227293T1 (de) 2,3-disubstituierte-(5,6)-heteroarylkondensiert - pyrimidin-4-one
MY129425A (en) Indole derivatives useful a.o. for the treatment of osteoporosis
CZ103595A3 (en) Derivative of 3-indolylpiperidine, process of its preparation, its use for preparing a pharmaceutical preparation and and the pharmaceutical composition containing thereof
ZA9710649B (en) Benzopyran compounds, process for preparing them and pharmaceutical compositions containing them.
PT992509E (pt) Novos derivados macrolidos
DK0628042T3 (da) Serotoninerge ergolinderivater
ATE202564T1 (de) Aminomethylheterozyclischederivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
KR950702953A (ko) 플루오레논 유도체, 이의 제조방법, 및 변성된 중추 또는 말초신경 복구제 및 중추 또는 말초신경 보호제(Fluorenone derivatives, process for preparing the same and central or peripheral nerve degeneration repair and protective agent)
ATE160566T1 (de) Amphotere tricyclische verbindungen als antihistaminische und antiallergische mittel
ATE195521T1 (de) Indolizinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
TNSN95099A1 (fr) Derives d'acides quinolone et naphtyridone-carboxyliques
DE69526595D1 (de) Pyridoncarbonsäurederivate substituiert von bicyclischer aminogruppe, deren ester und salze, und bicyclisches amin als zwischenprodukt davon
PT916671E (pt) Novos inibidores de metaloproteases processo para a sua preparacao e as suas composicoes farmaceuticas que os contem
DK0566288T3 (da) Flavon-derivater
EP0802179A4 (en) DERIVATE SUBSTITUTED AMIDINONAPHTHYLESTER
CS548987A2 (en) Process for preparing new tetracycline derivatives of indole
ATE205212T1 (de) Substituierte 7,12-dioxabenzo(a)anthracenderivate,verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ATE228359T1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
ATE243219T1 (de) 9a, 11b-dehydro derivative von 9-oxime-3-keto-6-0-methylerythromycin
HUP9902678A2 (hu) Protein kináz-C inhibitor hatású, halogénatommal szubsztituált bisz(indol)-maleinmid-származékok, valamint ezeket tartalmazó gyógyászati készítmények
MY103509A (en) Indole derivatives.
ZA9711708B (en) Ellipticine compounds, a process for their preparation and pharmaceutical compositions containing them.