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ZA978170B - Novel amino alcohol derivatives process for their manufacture and medical preparations containing these compounds - Google Patents

Novel amino alcohol derivatives process for their manufacture and medical preparations containing these compounds

Info

Publication number
ZA978170B
ZA978170B ZA978170A ZA978170A ZA978170B ZA 978170 B ZA978170 B ZA 978170B ZA 978170 A ZA978170 A ZA 978170A ZA 978170 A ZA978170 A ZA 978170A ZA 978170 B ZA978170 B ZA 978170B
Authority
ZA
South Africa
Prior art keywords
different
group
stand
radical
compounds
Prior art date
Application number
ZA978170A
Other languages
English (en)
Inventor
Walter-Gunar Friebe
Nikolaos Dimoudis
Use Michaelis
Bernhard Knipp
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA978170B publication Critical patent/ZA978170B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA978170A 1996-09-12 1997-09-11 Novel amino alcohol derivatives process for their manufacture and medical preparations containing these compounds ZA978170B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19637043A DE19637043A1 (de) 1996-09-12 1996-09-12 Neue Aminoalkoholderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel und Reagenzien

Publications (1)

Publication Number Publication Date
ZA978170B true ZA978170B (en) 1999-03-11

Family

ID=7805345

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA978170A ZA978170B (en) 1996-09-12 1997-09-11 Novel amino alcohol derivatives process for their manufacture and medical preparations containing these compounds

Country Status (12)

Country Link
EP (1) EP0927174B1 (xx)
JP (1) JP4191251B2 (xx)
KR (1) KR20000036063A (xx)
CN (1) CN1087293C (xx)
AT (1) ATE380798T1 (xx)
AU (1) AU741636B2 (xx)
BR (1) BR9712818A (xx)
CA (1) CA2265765A1 (xx)
DE (2) DE19637043A1 (xx)
TR (1) TR199901200T2 (xx)
WO (1) WO1998011082A1 (xx)
ZA (1) ZA978170B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0108876D0 (en) * 2001-04-09 2001-05-30 Novartis Ag Organic Compounds
KR101675174B1 (ko) * 2009-01-26 2016-11-10 이스라엘 인스티튜트 포 바이올로지컬 리서치 이환형 헤테로사이클릭 스피로 화합물
ES2828717T3 (es) 2015-06-24 2021-05-27 Nitto Denko Corp Compuestos ionizables y composiciones y usos de los mismos
US10800635B2 (en) 2017-08-30 2020-10-13 Otis Elevator Company Elevator door wedge monitoring system
EP4077272B1 (en) * 2020-04-09 2024-09-18 Suzhou Abogen Biosciences Co., Ltd. Lipid nanoparticle composition
TW202204622A (zh) 2020-04-09 2022-02-01 大陸商蘇州艾博生物科技有限公司 針對冠狀病毒之核酸疫苗
CN116710074A (zh) * 2020-10-14 2023-09-05 乔治梅森研究基金会公司 脂质纳米颗粒制造方法和由其衍生的组合物
JP2023546175A (ja) * 2020-10-14 2023-11-01 ジョージ・メイソン・リサーチ・ファウンデーション・インコーポレイテッド 脂質ナノ粒子製造の方法及びそれに由来する組成物
CN115947672B (zh) * 2023-01-04 2024-02-27 成都威斯津生物医药科技有限公司 用于递送药物的化合物、脂质体及药物载体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3689494A (en) * 1971-03-31 1972-09-05 William R J Simpson N-pyridinealkyl-alkanolamine nitrates
US4158093A (en) * 1977-12-15 1979-06-12 Reilly Tar & Chemical Corporation Process for substituting and dequaternizing pyridylethyl quaternary salts of pyridine and bypyridine bases
JPS6325654A (ja) * 1986-07-18 1988-02-03 Fuji Photo Film Co Ltd カラ−写真現像液組成物及びハロゲン化銀カラ−写真感光材料の処理方法
JPH05232660A (ja) * 1992-02-19 1993-09-10 Konica Corp ハロゲン化銀カラー写真感光材料の処理方法
JP2588339B2 (ja) * 1992-06-02 1997-03-05 花王株式会社 新規ジアミノジエステル及びその製造法
US5334761A (en) * 1992-08-28 1994-08-02 Life Technologies, Inc. Cationic lipids
JPH06340598A (ja) * 1993-05-28 1994-12-13 Lion Corp 新規なジエステルジアミン化合物、その中間体及びその製造方法と柔軟剤
US5491263A (en) * 1993-12-21 1996-02-13 The Dow Chemical Company Aminoethylation process for production of substituted ethylene diamines
FR2717694B1 (fr) * 1994-03-22 1996-05-03 Seppic Sa Une composition comprenant un plasmide recombinant et ses utilisations comme vaccin et médicament.
FR2727679B1 (fr) * 1994-12-05 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux agents de transfection et leurs applications pharmaceutiques
US5635487A (en) * 1994-12-29 1997-06-03 Wolff; Jon A. Amphipathic, micellar delivery systems for biologically active polyions
DE19521412A1 (de) * 1995-06-14 1996-12-19 Boehringer Mannheim Gmbh Neue kationische und polykationische Amphiphile, diese enthaltende Reagenzien und deren Verwendung

Also Published As

Publication number Publication date
CN1087293C (zh) 2002-07-10
JP4191251B2 (ja) 2008-12-03
JP2001504806A (ja) 2001-04-10
EP0927174B1 (de) 2007-12-12
BR9712818A (pt) 1999-12-21
ATE380798T1 (de) 2007-12-15
CA2265765A1 (en) 1998-03-19
CN1237161A (zh) 1999-12-01
AU4384197A (en) 1998-04-02
KR20000036063A (ko) 2000-06-26
WO1998011082A1 (de) 1998-03-19
DE59712902D1 (de) 2008-01-24
AU741636B2 (en) 2001-12-06
TR199901200T2 (xx) 1999-10-21
EP0927174A1 (de) 1999-07-07
DE19637043A1 (de) 1998-03-19

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