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ZA93958B - Piperazine and piperidine derivatives and their use in therapy - Google Patents

Piperazine and piperidine derivatives and their use in therapy

Info

Publication number
ZA93958B
ZA93958B ZA93958A ZA93958A ZA93958B ZA 93958 B ZA93958 B ZA 93958B ZA 93958 A ZA93958 A ZA 93958A ZA 93958 A ZA93958 A ZA 93958A ZA 93958 B ZA93958 B ZA 93958B
Authority
ZA
South Africa
Prior art keywords
piperazine
therapy
piperidine derivatives
piperidine
derivatives
Prior art date
Application number
ZA93958A
Inventor
Mark Henry Norman
Iii Frank Navas
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZA93958B publication Critical patent/ZA93958B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ZA93958A 1992-02-12 1993-02-11 Piperazine and piperidine derivatives and their use in therapy ZA93958B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929202915A GB9202915D0 (en) 1992-02-12 1992-02-12 Chemical compounds

Publications (1)

Publication Number Publication Date
ZA93958B true ZA93958B (en) 1994-08-11

Family

ID=10710223

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA93958A ZA93958B (en) 1992-02-12 1993-02-11 Piperazine and piperidine derivatives and their use in therapy

Country Status (16)

Country Link
EP (1) EP0625978A1 (en)
JP (1) JPH07503723A (en)
KR (1) KR950700290A (en)
AU (1) AU3460393A (en)
CA (1) CA2117434A1 (en)
CZ (1) CZ194994A3 (en)
FI (1) FI943718A0 (en)
GB (1) GB9202915D0 (en)
HU (1) HUT72309A (en)
IL (1) IL104690A0 (en)
MX (1) MX9300786A (en)
NO (1) NO942977L (en)
RU (1) RU94038064A (en)
SK (1) SK96494A3 (en)
WO (1) WO1993016073A1 (en)
ZA (1) ZA93958B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11246905B2 (en) 2016-08-15 2022-02-15 President And Fellows Of Harvard College Treating infections using IdsD from Proteus mirabilis

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US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
RU2118322C1 (en) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-dihydro-1,4-benzodioxine-5-yl-pyrerazine derivatives and salts thereof
US5874429A (en) * 1993-12-24 1999-02-23 Suntory Limited Benzothiazine derivative
JPH0912562A (en) * 1995-06-22 1997-01-14 Suntory Ltd Substituted benzothiazine derivative
US6001827A (en) * 1993-12-24 1999-12-14 Suntory Limited Benzothiazine derivative
CN1058492C (en) * 1993-12-24 2000-11-15 三得利株式会社 Benzothiazine Derivatives
WO1996014297A1 (en) * 1994-11-04 1996-05-17 Sumitomo Pharmaceuticals Company, Limited Novel lactam derivatives
DK0732332T3 (en) * 1995-03-17 2002-04-15 Aventis Pharma Inc Substituted benzothienylpiperazines, their use as drugs and their methods of preparation
US6087364A (en) * 1998-01-29 2000-07-11 Warner-Lambert Company Dopamine D4 receptor antagonists
DE19814084B4 (en) 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2 agonist-containing transdermal therapeutic system for the treatment of Parkinson's syndrome and process for its preparation
US7030142B1 (en) 1999-04-06 2006-04-18 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites
CA2363942A1 (en) * 1999-04-06 2000-10-12 Sepracor Inc. Methods and compositions for the treatment of psychotic and related disorders using ziprasidone metabolites
AR028685A1 (en) 2000-06-14 2003-05-21 Lundbeck & Co As H INDOL DERIVATIVES
DE10041478A1 (en) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh New pharmaceutical composition
DE10234673B4 (en) 2002-07-30 2007-08-16 Schwarz Pharma Ag Hot-melt TTS for the administration of rotigotine and process for its preparation, and use of rotigotine in the manufacture of a hot-melt TTS
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
ES2685780T3 (en) 2002-08-22 2018-10-11 Sumitomo Dainippon Pharma Co., Ltd. Agent for the treatment of schizophrenia
SI1426049T1 (en) 2002-12-02 2005-08-31 Sanol Arznei Schwarz Gmbh Iontophoretic delivery of rotigotine for the treatment of Parkinson's disease
DE10261696A1 (en) 2002-12-30 2004-07-15 Schwarz Pharma Ag Device for the transdermal administration of rotigotine base
CA2531980C (en) * 2003-06-23 2013-09-17 Dainippon Sumitomo Pharma Co., Ltd. Imide derivatives as therapeutic agents for senile dementia
DE10334188B4 (en) 2003-07-26 2007-07-05 Schwarz Pharma Ag Use of rotigotine to treat depression
US20070160537A1 (en) 2004-02-20 2007-07-12 Takeo Ishiyama In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia
BRPI0720323A2 (en) * 2007-01-03 2016-08-09 Cortex Pharma Inc compound, method of treatment, pharmaceutical composition and use of the compound
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder
EP2736905A4 (en) 2011-07-28 2015-07-29 Mapi Pharma Ltd Intermediate compounds and process for the preparation of lurasidone and salts thereof
US9901577B2 (en) * 2013-07-31 2018-02-27 Merck Patent Gmbh Oxoquinazolinyl-butanamide derivatives
CN105669665A (en) * 2016-03-15 2016-06-15 烟台贝森医药科技有限公司 Preparation method of perospirone
CN115124464B (en) * 2022-07-04 2023-06-06 新乡学院 A kind of quinoline dione sulfonyl piperazine hybrid and its preparation method and application

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2258843B1 (en) * 1974-01-30 1977-09-09 Roussel Uclaf
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
JPH0625181B2 (en) * 1985-03-27 1994-04-06 住友製薬株式会社 New imide derivative
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
NZ230045A (en) * 1988-08-05 1990-11-27 Janssen Pharmaceutica Nv 3-piperazinylbenzazole derivatives and pharmaceutical compositions
US4968792A (en) * 1989-09-25 1990-11-06 American Home Products Corporation Psychotropic benzisothiazole derivatives
JP2800953B2 (en) * 1990-07-06 1998-09-21 住友製薬株式会社 New imide derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11246905B2 (en) 2016-08-15 2022-02-15 President And Fellows Of Harvard College Treating infections using IdsD from Proteus mirabilis

Also Published As

Publication number Publication date
CA2117434A1 (en) 1993-08-19
IL104690A0 (en) 1993-06-10
FI943718A7 (en) 1994-08-11
GB9202915D0 (en) 1992-03-25
FI943718L (en) 1994-08-11
NO942977L (en) 1994-10-10
CZ194994A3 (en) 1995-09-13
WO1993016073A1 (en) 1993-08-19
JPH07503723A (en) 1995-04-20
AU3460393A (en) 1993-09-03
FI943718A0 (en) 1994-08-11
EP0625978A1 (en) 1994-11-30
MX9300786A (en) 1994-03-31
KR950700290A (en) 1995-01-16
NO942977D0 (en) 1994-08-11
HU9402343D0 (en) 1994-10-28
HUT72309A (en) 1996-04-29
RU94038064A (en) 1997-05-27
SK96494A3 (en) 1995-07-11

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