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ZA929568B - 4-amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion - Google Patents

4-amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion

Info

Publication number
ZA929568B
ZA929568B ZA929568A ZA929568A ZA929568B ZA 929568 B ZA929568 B ZA 929568B ZA 929568 A ZA929568 A ZA 929568A ZA 929568 A ZA929568 A ZA 929568A ZA 929568 B ZA929568 B ZA 929568B
Authority
ZA
South Africa
Prior art keywords
inhibitors
amino
gastric acid
acid secretion
quinoline derivatives
Prior art date
Application number
ZA929568A
Inventor
Robert John Ife
Gerhard Grundler
Georg Rainer
Hartmann Schaefer
Colin Andrew Leach
Stefan Positius
Wolfgang Alexander Simon
Jorg Senn-Bilfinger
Richard Riedel
Original Assignee
Smithkline Beecham Intercredit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Intercredit filed Critical Smithkline Beecham Intercredit
Publication of ZA929568B publication Critical patent/ZA929568B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA929568A 1991-12-12 1992-12-10 4-amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion ZA929568B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919126438A GB9126438D0 (en) 1991-12-12 1991-12-12 New quinoline derivatives

Publications (1)

Publication Number Publication Date
ZA929568B true ZA929568B (en) 1994-06-10

Family

ID=10706172

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA929568A ZA929568B (en) 1991-12-12 1992-12-10 4-amino-3-acyl quinoline derivatives and their use as inhibitors of gastric acid secretion

Country Status (8)

Country Link
EP (1) EP0642500A1 (en)
JP (1) JPH07501812A (en)
AU (1) AU665223B2 (en)
CA (1) CA2125681A1 (en)
GB (1) GB9126438D0 (en)
MX (1) MX9207162A (en)
WO (1) WO1993012090A1 (en)
ZA (1) ZA929568B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS4164A (en) * 1993-06-11 1994-12-12 Ab Astra Compounds that inhibit gastric acid flow
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
UA80393C2 (en) 2000-12-07 2007-09-25 Алтана Фарма Аг Pharmaceutical preparation comprising an pde inhibitor dispersed on a matrix
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
MA22401A1 (en) * 1991-01-29 1992-10-01 Smithkline Beecham Intercredit PROCESS FOR THE PREPARATION OF GUINOLEIN SALTS

Also Published As

Publication number Publication date
WO1993012090A1 (en) 1993-06-24
EP0642500A1 (en) 1995-03-15
AU3158593A (en) 1993-07-19
AU665223B2 (en) 1995-12-21
MX9207162A (en) 1994-08-31
JPH07501812A (en) 1995-02-23
CA2125681A1 (en) 1993-06-24
GB9126438D0 (en) 1992-02-12

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