ZA915239B - Novel antiviral tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones - Google Patents

Novel antiviral tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones

Info

Publication number: ZA915239B
Authority: ZA; South Africa
Prior art keywords: benzodiazepin; thi; ones; novel antiviral; tetrahydroimidazo
Prior art date: 1990-07-06

Application number

ZA915239A

Other languages

English (en)

Inventor

Michael J Kukla

Henry J Breslin

Alfons H M Raeymaekers

Gelder Josephus L H Van

Paul A J Janssen

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-06

Filing date

1991-07-05

Publication date

1993-03-31

1991-07-05 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1993-03-31 Publication of ZA915239B publication Critical patent/ZA915239B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA915239A 1990-07-06 1991-07-05 Novel antiviral tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones ZA915239B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US54934990A	1990-07-06	1990-07-06

Publications (1)

Publication Number	Publication Date
ZA915239B true ZA915239B (en)	1993-03-31

Family

ID=24192641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA915239A ZA915239B (en)	1990-07-06	1991-07-05	Novel antiviral tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones

Country Status (29)

Country	Link
EP (1)	EP0538297B9 (xx)
JP (1)	JPH05508632A (xx)
CN (1)	CN1034122C (xx)
AP (1)	AP262A (xx)
AT (1)	ATE205848T1 (xx)
AU (1)	AU644192B2 (xx)
CA (1)	CA2086547A1 (xx)
CZ (1)	CZ279900B6 (xx)
DE (1)	DE69132738T2 (xx)
DK (1)	DK0538297T3 (xx)
ES (1)	ES2164044T3 (xx)
FI (1)	FI930024A0 (xx)
HU (1)	HUT68382A (xx)
IE (1)	IE912363A1 (xx)
IL (1)	IL98726A (xx)
MA (1)	MA22205A1 (xx)
MX (1)	MX9100103A (xx)
MY (1)	MY106786A (xx)
NO (1)	NO300420B1 (xx)
NZ (1)	NZ238664A (xx)
OA (1)	OA09769A (xx)
PL (3)	PL169613B1 (xx)
PT (1)	PT98225B (xx)
SK (1)	SK278442B6 (xx)
TN (1)	TNSN91055A1 (xx)
TW (1)	TW211014B (xx)
WO (1)	WO1992000979A1 (xx)
YU (1)	YU48176B (xx)
ZA (1)	ZA915239B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6177435B1 (en)	1992-05-13	2001-01-23	Glaxo Wellcome Inc.	Therapeutic combinations
AU4079593A (en) *	1992-05-13	1993-12-13	Wellcome Foundation Limited, The	Therapeutic combinations
US5665720A (en) *	1992-08-07	1997-09-09	Merck & Co., Inc.	Benzoxazinones as inhibitors of HIV reverse transcriptase
US6420357B1 (en)	1997-12-23	2002-07-16	Instituto Biomar, S.A.	Cytotoxic alkaloid derivatives including Asmarine A and B isolated from a sponge
BR0207297A (pt)	2001-02-15	2005-04-19	King Pharmaceuticals Inc	Composição farmacêutica em forma sólida e método de preparar uma forma de dosagem sólida de um ingrediente farmaceuticamente ativo
US7101569B2 (en)	2001-08-14	2006-09-05	Franz G Andrew	Methods of administering levothyroxine pharmaceutical compositions
RU2440120C1 (ru) *	2010-11-19	2012-01-20	Государственное Учебно-Научное Учреждение Химический Факультет Московского Государственного Университета Имени М.В. Ломоносова	КОМПОЗИЦИЯ ДЛЯ ИНЪЕКЦИЙ НА ОСНОВЕ КРИСТАЛЛИЧЕСКОЙ β-МОДИФИКАЦИИ 7-БРОМ-1,3-ДИГИДРО-5-(2-ХЛОРФЕНИЛ)-2Н-1,4-БЕНЗОДИАЗЕПИН-2-ОНА, ОБЛАДАЮЩАЯ ТРАНКВИЛИЗИРУЮЩИМ ДЕЙСТВИЕМ И СПОСОБ ЕЕ ПОЛУЧЕНИЯ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8806449D0 (en) *	1988-03-18	1988-04-20	Janssen Pharmaceutica Nv	Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) *	1989-02-23	1995-01-24	Janssen Pharmaceutica Nv	Tetrahydroimidazo (1,4) benzodiazepin-2-thione derivatives, their preparation and pharmaceutical compositions containing them
NZ235137A (en) *	1989-09-13	1992-02-25	Janssen Pharmaceutica Nv	Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof
DE4036552C1 (xx) *	1990-11-16	1992-02-06	Boehringer Mannheim Gmbh, 6800 Mannheim, De

1991
- 1991-06-21 NZ NZ238664A patent/NZ238664A/en unknown
- 1991-06-28 DE DE69132738T patent/DE69132738T2/de not_active Expired - Fee Related
- 1991-06-28 AU AU80683/91A patent/AU644192B2/en not_active Ceased
- 1991-06-28 AT AT91912145T patent/ATE205848T1/de not_active IP Right Cessation
- 1991-06-28 ES ES91912145T patent/ES2164044T3/es not_active Expired - Lifetime
- 1991-06-28 PL PL91309618A patent/PL169613B1/pl unknown
- 1991-06-28 WO PCT/EP1991/001224 patent/WO1992000979A1/en not_active Ceased
- 1991-06-28 PL PL91297379A patent/PL168320B1/pl unknown
- 1991-06-28 CA CA002086547A patent/CA2086547A1/en not_active Abandoned
- 1991-06-28 DK DK91912145T patent/DK0538297T3/da active
- 1991-06-28 EP EP91912145A patent/EP0538297B9/en not_active Expired - Lifetime
- 1991-06-28 PL PL91309617A patent/PL169662B1/pl unknown
- 1991-06-28 JP JP91511094A patent/JPH05508632A/ja active Pending
- 1991-06-28 HU HU9300011A patent/HUT68382A/hu unknown
- 1991-07-02 MY MYPI91001205A patent/MY106786A/en unknown
- 1991-07-04 SK SK2065-91A patent/SK278442B6/sk unknown
- 1991-07-04 CZ CS912065A patent/CZ279900B6/cs unknown
- 1991-07-04 IL IL9872691A patent/IL98726A/en active IP Right Grant
- 1991-07-05 MA MA22478A patent/MA22205A1/fr unknown
- 1991-07-05 ZA ZA915239A patent/ZA915239B/xx unknown
- 1991-07-05 MX MX9100103A patent/MX9100103A/es not_active IP Right Cessation
- 1991-07-05 YU YU119491A patent/YU48176B/sh unknown
- 1991-07-05 IE IE236391A patent/IE912363A1/en unknown
- 1991-07-05 PT PT98225A patent/PT98225B/pt not_active IP Right Cessation
- 1991-07-05 AP APAP/P/1991/000289A patent/AP262A/en active
- 1991-07-05 TN TNTNSN91055A patent/TNSN91055A1/fr unknown
- 1991-07-06 CN CN91104581A patent/CN1034122C/zh not_active Expired - Fee Related
- 1991-08-02 TW TW080106042A patent/TW211014B/zh active
1992
- 1992-12-15 NO NO924853A patent/NO300420B1/no unknown
1993
- 1993-01-05 FI FI930024A patent/FI930024A0/fi not_active Application Discontinuation
- 1993-01-05 OA OA60328A patent/OA09769A/fr unknown

Also Published As

Publication number	Publication date
PL169613B1 (pl)	1996-08-30
HU9300011D0 (en)	1993-04-28
DE69132738D1 (de)	2001-10-25
IE912363A1 (en)	1992-01-15
CA2086547A1 (en)	1992-01-07
PT98225A (pt)	1992-05-29
EP0538297A1 (en)	1993-04-28
HUT68382A (en)	1995-06-28
CN1034122C (zh)	1997-02-26
AU8068391A (en)	1992-02-04
FI930024A7 (fi)	1993-01-05
MX9100103A (es)	1992-02-28
NO924853D0 (no)	1992-12-15
YU119491A (sh)	1994-06-10
DK0538297T3 (da)	2001-12-27
AP262A (en)	1993-06-03
MA22205A1 (fr)	1992-04-01
PL168320B1 (pl)	1996-02-29
EP0538297B1 (en)	2001-09-19
WO1992000979A1 (en)	1992-01-23
NZ238664A (en)	1992-12-23
JPH05508632A (ja)	1993-12-02
CZ279900B6 (cs)	1995-08-16
OA09769A (fr)	1993-11-30
NO300420B1 (no)	1997-05-26
AP9100289A0 (en)	1991-07-31
ATE205848T1 (de)	2001-10-15
SK278442B6 (en)	1997-05-07
AU644192B2 (en)	1993-12-02
FI930024A0 (fi)	1993-01-05
NO924853L (no)	1992-12-15
TW211014B (xx)	1993-08-11
IL98726A (en)	1996-01-31
PT98225B (pt)	1998-12-31
DE69132738T2 (de)	2002-07-04
EP0538297B9 (en)	2002-10-16
PL297379A1 (xx)	1992-07-13
CN1057840A (zh)	1992-01-15
CS206591A3 (en)	1992-03-18
ES2164044T3 (es)	2002-02-16
TNSN91055A1 (fr)	1992-10-25
IL98726A0 (en)	1992-07-15
MY106786A (en)	1995-07-31
PL169662B1 (en)	1996-08-30
YU48176B (sh)	1997-07-31

Publication	Publication Date	Title
GR3001763T3 (en)	1992-11-23	Cycloalkano(1,2-b)indole-sulfonamides
EP0525106A4 (en)	1993-04-21	2',3'-dideoxy-4'-thioribonucleosides as antiviral agents
CY1868A (en)	1996-04-05	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
ZA917516B (en)	1992-06-24	Substituted 5-alkoxy-1,2,4-triazol-3-(thi)ones
AP9100289A0 (en)	1991-07-31	Novel antiviral tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones
EP0481950A3 (en)	1992-09-02	1,4-dideoxy-4-fluoronojirimycin
GB8911158D0 (en)	1989-07-05	Antiviral pyridazinamines
AP9000205A0 (en)	1990-10-31	Antiviral tetrahydroimidazo(1,4)benzodia-zepines
HU913371D0 (en)	1992-01-28	Substituted tieno(3,2-b)pyran-5,7-diones
GB9001119D0 (en)	1990-03-21	Antiviral tetrahydroimidazo(1,4)-benzodiazepin-2-selones
GB8904108D0 (en)	1989-04-05	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
GB8920354D0 (en)	1989-10-25	Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
EP0544743A4 (en)	1994-05-18	Lymphokine 154
CS594886A1 (en)	1987-09-17	Sposob vyroby derivatov 2,1,3 benzotiadiazin 4 on 2,2 dioxidu
ZA871249B (en)	1987-08-12	Cycloalkano(1,2-b)-indole-sulphonamides
SG118594G (en)	1994-11-25	Antiviral tetrahydroimidazo [1,4] benzodiazepin-2-thiones
GB8904962D0 (en)	1989-04-12	Antiviral uses
GB8922397D0 (en)	1989-11-22	Antiviral pentofuranosides
CS634386A1 (en)	1987-07-16	X 2 (2 benzotiazolyl) 1,3 indandiony
IE900472L (en)	1990-08-11	2,3,23-trihydroxy-urs-12-ene
IE902043L (en)	1990-12-08	2,5-diaryltetrahydrofurans
IE900875L (en)	1990-09-13	1,4-dihydro-4-oxo-naphthyridine-3-carboxylate
CS553587A1 (en)	1988-06-15	1 2 alkyltio 6 benzotiazolylaminometyl 5 3,4 di chlorfenyl 1,2,3,4 tetrazoly
IE890468L (en)	1989-08-16	2', 3' - dideoxy-2',2'-difluoronucleosides
CS161787A1 (en)	1988-07-15	N oxidy 2,2,5 trimetyl 3 alkyloxazolidinov