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ZA855814B - New p-phenylenediamine-peptides and reagents containing these for the determination of proteases of the blood coagulation systems - Google Patents

New p-phenylenediamine-peptides and reagents containing these for the determination of proteases of the blood coagulation systems

Info

Publication number
ZA855814B
ZA855814B ZA855814A ZA855814A ZA855814B ZA 855814 B ZA855814 B ZA 855814B ZA 855814 A ZA855814 A ZA 855814A ZA 855814 A ZA855814 A ZA 855814A ZA 855814 B ZA855814 B ZA 855814B
Authority
ZA
South Africa
Prior art keywords
phenylenediamine
proteases
peptides
determination
new
Prior art date
Application number
ZA855814A
Inventor
Knut Bartl
Udo Becker
Herbert Von Der Eltz
Helmut Lill
Hans-Georg Batz
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA855814B publication Critical patent/ZA855814B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675Beta-endorphins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10Anilides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/755Factors VIII, e.g. factor VIII C [AHF], factor VIII Ag [VWF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
ZA855814A 1984-08-02 1985-08-01 New p-phenylenediamine-peptides and reagents containing these for the determination of proteases of the blood coagulation systems ZA855814B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843428543 DE3428543A1 (en) 1984-08-02 1984-08-02 NEW P-PHENYLENE DIAMINE PEPTIDES AND REAGENTS CONTAINING THESE FOR DETERMINING PROTEASES OF THE BLOOD CLOTHING SYSTEM

Publications (1)

Publication Number Publication Date
ZA855814B true ZA855814B (en) 1986-04-30

Family

ID=6242223

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855814A ZA855814B (en) 1984-08-02 1985-08-01 New p-phenylenediamine-peptides and reagents containing these for the determination of proteases of the blood coagulation systems

Country Status (6)

Country Link
EP (1) EP0190299A1 (en)
JP (1) JPS61501635A (en)
AU (1) AU564556B2 (en)
DE (1) DE3428543A1 (en)
WO (1) WO1986001209A2 (en)
ZA (1) ZA855814B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4717658A (en) * 1985-12-03 1988-01-05 Miles Inc. Gram negative bacteria screening method with horseshoe crab amebocyte lysate (LAL)
FI860043A7 (en) * 1986-01-06 1987-07-07 Orion Yhtymae Oy Peptide substrates and a method for the quantitative determination of endotoxin.
SE8601327D0 (en) * 1986-03-21 1986-03-21 Kabivitrum Ab NEW PEPTIDE DERIVATIVES
SE461494B (en) * 1986-03-21 1990-02-19 Thorsman & Co Ab MACHINE CONTAINS AN ELECTRIC CLUTCH BOX
FR2644697B1 (en) * 1989-03-24 1992-05-15 Poudres & Explosifs Ste Nale ANESTHETIC COMPOUNDS WITH CONTROLLED DURATION OF ACTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US6207399B1 (en) 1995-01-10 2001-03-27 Hendrik Coenraad Hemker Methods of determining endogenous thrombin potential (ETP) and thrombin substrates for use in said methods
IL144839A0 (en) * 1999-02-23 2002-06-30 Pentapharm Ag Oligopeptide derivatives for the electrochemical measurement of protease activity
JP4878031B2 (en) 2004-10-12 2012-02-15 エフ.ホフマン−ラ ロシュ アーゲー Solid phase peptide synthesis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2497798A1 (en) * 1981-01-09 1982-07-16 Pharmindustrie NOVEL PEPTIDES CARRYING A FLUOROPHORE, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION TO FLUORIMETRIC DETERMINATION OF ENDOTOXINS
JPS57176940A (en) * 1981-04-25 1982-10-30 Wako Pure Chem Ind Ltd Novel color-developing peptide derivative
JPS58172354A (en) * 1982-04-05 1983-10-11 Dai Ichi Pure Chem Co Ltd Peptide derivative
GB2118190B (en) * 1982-04-13 1985-05-01 Erba Farmitalia Peptides with sauvagine-like activity
DE3244030A1 (en) * 1982-11-27 1984-05-30 Behringwerke Ag, 3550 Marburg CHROMOGENIC COMPOUNDS, METHOD FOR THEIR PRODUCTION AND THEIR USE
JPH08142597A (en) * 1994-11-21 1996-06-04 Dainippon Printing Co Ltd Transfer foil and decorative glass using the same

Also Published As

Publication number Publication date
AU564556B2 (en) 1987-08-13
DE3428543A1 (en) 1986-02-13
WO1986001209A3 (en) 1986-03-27
JPS61501635A (en) 1986-08-07
EP0190299A1 (en) 1986-08-13
AU4723885A (en) 1986-03-07
WO1986001209A2 (en) 1986-02-27

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