ZA813093B - Cyclopropane derivatives,pharmaceutical formulations containing these and processes for their preparation - Google Patents
Cyclopropane derivatives,pharmaceutical formulations containing these and processes for their preparationInfo
- Publication number
- ZA813093B ZA813093B ZA00813093A ZA813093A ZA813093B ZA 813093 B ZA813093 B ZA 813093B ZA 00813093 A ZA00813093 A ZA 00813093A ZA 813093 A ZA813093 A ZA 813093A ZA 813093 B ZA813093 B ZA 813093B
- Authority
- ZA
- South Africa
- Prior art keywords
- processes
- preparation
- pharmaceutical formulations
- formulations containing
- cyclopropane derivatives
- Prior art date
Links
- 125000001559 cyclopropyl group Chemical class [H]C1([H])C([H])([H])C1([H])* 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- -1 methylenedioxy Chemical group 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803017812 DE3017812A1 (de) | 1980-05-09 | 1980-05-09 | Cyclopropanderivate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA813093B true ZA813093B (en) | 1982-05-26 |
Family
ID=6102013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00813093A ZA813093B (en) | 1980-05-09 | 1981-05-08 | Cyclopropane derivatives,pharmaceutical formulations containing these and processes for their preparation |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4500541A (xx) |
| EP (1) | EP0039771B1 (xx) |
| JP (1) | JPS574950A (xx) |
| AT (1) | ATE5068T1 (xx) |
| AU (1) | AU540658B2 (xx) |
| CA (1) | CA1178597A (xx) |
| DE (2) | DE3017812A1 (xx) |
| ES (1) | ES8301887A1 (xx) |
| HU (1) | HU186768B (xx) |
| IL (1) | IL62815A (xx) |
| ZA (1) | ZA813093B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6030038U (ja) * | 1983-08-08 | 1985-02-28 | アルプス電気株式会社 | 入力装置 |
| US4609758A (en) * | 1985-05-09 | 1986-09-02 | American Home Products Corporation | Phenoxyethylamine derivatives |
| US4956388A (en) * | 1986-12-22 | 1990-09-11 | Eli Lilly And Company | 3-aryloxy-3-substituted propanamines |
| ZA885824B (en) * | 1987-08-14 | 1989-04-26 | Merrell Dow Pharma | Novel antidepressants |
| DK630987D0 (da) * | 1987-12-01 | 1987-12-01 | Ferrosan As | Aryloxyphenylpropylaminer, deres fremstilling og anvendelse |
| US5238959A (en) * | 1988-04-08 | 1993-08-24 | Eli Lilly And Company | 3-phenyloxy-3-phenyl propanamines |
| US5166437A (en) * | 1989-03-03 | 1992-11-24 | Orion-Yhtyma Oy | Process for the preparation of fluoxetine |
| US6291409B1 (en) * | 1998-07-02 | 2001-09-18 | Cargill, Inc. | Process for modifying unsaturated triacylglycerol oils; Resulting products and uses thereof |
| US6051539A (en) * | 1998-07-02 | 2000-04-18 | Cargill, Inc. | Process for modifying unsaturated triacylglycerol oils resulting products and uses thereof |
| US6992037B2 (en) * | 2001-09-17 | 2006-01-31 | Engelhard Corporation | Precious metal catalyst for debenzylation |
| US7659225B2 (en) * | 2001-09-17 | 2010-02-09 | Basf Catalysts Llc | Precious metal catalyst for debenzylation |
| WO2006021564A1 (en) * | 2004-08-26 | 2006-03-02 | Neurosearch A/S | Novel substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors |
| EP1786778A1 (en) * | 2004-08-26 | 2007-05-23 | Neurosearch A/S | Novel substituted heteroaryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT196386B (de) * | 1954-04-08 | 1958-03-10 | Pharmazeutische Fabrik Montavit Gmbh | Verfahren zur Herstellung von am Stickstoff symmetrisch oder unsymmetrisch disubstituierten Aminoalkyläthern aromatisch-aliphatischer Alkohole und deren Salzen |
| GB951461A (en) * | 1959-11-17 | 1964-03-04 | Smith Kline French Lab | Improvements in or relating to substituted 2-phenoxy-cyclopropylamines |
| US3253040A (en) * | 1962-12-10 | 1966-05-24 | Union Carbide Corp | Process for the production of primary 3-hydrocarbyloxypropylamines |
| CH490335A (de) * | 1963-11-05 | 1970-05-15 | Whitefin Holding Sa | Verfahren zur Herstellung von neuen Phenylzyklopropanverbindungen |
| US3928426A (en) * | 1972-01-28 | 1975-12-23 | Robins Co Inc A H | 1-Cyclopropyl-1-phenyl-omega-amino-1-lower alkanoyloxyalkanes |
| US4314081A (en) * | 1974-01-10 | 1982-02-02 | Eli Lilly And Company | Arloxyphenylpropylamines |
| US4207343A (en) * | 1978-06-22 | 1980-06-10 | Eli Lilly And Company | 1-Phenyl-3-(substituted phenoxy)propylamines |
-
1980
- 1980-05-09 DE DE19803017812 patent/DE3017812A1/de not_active Withdrawn
-
1981
- 1981-03-30 DE DE8181102377T patent/DE3161219D1/de not_active Expired
- 1981-03-30 EP EP81102377A patent/EP0039771B1/de not_active Expired
- 1981-03-30 AT AT81102377T patent/ATE5068T1/de not_active IP Right Cessation
- 1981-04-08 AU AU69184/81A patent/AU540658B2/en not_active Ceased
- 1981-05-06 IL IL62815A patent/IL62815A/xx unknown
- 1981-05-07 CA CA000377048A patent/CA1178597A/en not_active Expired
- 1981-05-08 ES ES502029A patent/ES8301887A1/es not_active Expired
- 1981-05-08 JP JP6839481A patent/JPS574950A/ja active Pending
- 1981-05-08 ZA ZA00813093A patent/ZA813093B/xx unknown
- 1981-05-08 HU HU811235A patent/HU186768B/hu unknown
-
1983
- 1983-06-17 US US06/505,558 patent/US4500541A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES502029A0 (es) | 1983-01-01 |
| ATE5068T1 (de) | 1983-11-15 |
| IL62815A0 (en) | 1981-07-31 |
| DE3161219D1 (en) | 1983-11-24 |
| AU540658B2 (en) | 1984-11-29 |
| EP0039771A1 (de) | 1981-11-18 |
| IL62815A (en) | 1984-08-31 |
| ES8301887A1 (es) | 1983-01-01 |
| US4500541A (en) | 1985-02-19 |
| JPS574950A (en) | 1982-01-11 |
| EP0039771B1 (de) | 1983-10-19 |
| AU6918481A (en) | 1981-11-12 |
| HU186768B (en) | 1985-09-30 |
| CA1178597A (en) | 1984-11-27 |
| DE3017812A1 (de) | 1981-11-12 |
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