ZA201001066B - Novel forms of CDDO methyl ester - Google Patents

Novel forms of CDDO methyl ester

Info

Publication number: ZA201001066B
Authority: ZA; South Africa
Prior art keywords: methyl ester; novel forms; cddo methyl; cddo; novel
Prior art date: 2007-08-15

Application number

ZA201001066A

Other languages

English (en)

Inventor

John Walling

Stephan D Parent

David T Jonaitis

Robert M Kral

Original Assignee

Reata Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-15

Filing date

2010-02-12

Publication date

2010-10-27

2010-02-12 Application filed by Reata Pharmaceuticals Inc filed Critical Reata Pharmaceuticals Inc

2010-10-27 Publication of ZA201001066B publication Critical patent/ZA201001066B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Steroid Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Glass Compositions (AREA)

ZA201001066A 2007-08-15 2010-02-12 Novel forms of CDDO methyl ester ZA201001066B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US95593907P	2007-08-15	2007-08-15

Publications (1)

Publication Number	Publication Date
ZA201001066B true ZA201001066B (en)	2010-10-27

Family

ID=40351005

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA201001066A ZA201001066B (en)	2007-08-15	2010-02-12	Novel forms of CDDO methyl ester

Country Status (28)

Country	Link
US (3)	US8088824B2 (fr)
EP (2)	EP2450057B1 (fr)
JP (4)	JP5005812B2 (fr)
KR (2)	KR101481764B1 (fr)
CN (2)	CN101820758B (fr)
AR (2)	AR073155A1 (fr)
AT (1)	ATE549035T1 (fr)
AU (1)	AU2008287388B2 (fr)
BR (1)	BRPI0815540A8 (fr)
CA (2)	CA2871864C (fr)
CL (1)	CL2008002417A1 (fr)
CY (2)	CY1112864T1 (fr)
DK (2)	DK2187741T3 (fr)
EA (2)	EA018704B1 (fr)
ES (2)	ES2382571T3 (fr)
HR (2)	HRP20120350T1 (fr)
HU (1)	HUE031866T2 (fr)
IL (2)	IL203824A (fr)
LT (1)	LT2450057T (fr)
MX (1)	MX2010001628A (fr)
NZ (1)	NZ583269A (fr)
PL (2)	PL2187741T3 (fr)
PT (2)	PT2450057T (fr)
SG (2)	SG177905A1 (fr)
SI (2)	SI2187741T1 (fr)
TW (2)	TWI486357B (fr)
WO (1)	WO2009023232A1 (fr)
ZA (1)	ZA201001066B (fr)

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WO2008064132A2 (fr)	2006-11-17	2008-05-29	Trustees Of Dartmouth College	Triterpénoïdes synthétiques et bis-énones tricycliques pour une utilisation dans la stimulation de croissance osseuse et cartilagineuse
US8921340B2 (en)	2006-11-17	2014-12-30	Trustees Of Dartmouth College	Methods for using synthetic triterpenoids in the treatment of bone or cartilage diseases or conditions
CA2670099A1 (fr)	2006-11-17	2008-05-29	Trustees Of Dartmouth College	Synthese et activites biologiques de nouveaux composes tricycliques-bis-enones (tbe)
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JP5529851B2 (ja)	2008-04-18	2014-06-25	リアタファーマシューティカルズインコーポレイテッド	抗酸化炎症モジュレーター：ｃ−１７においてアミノ改変およびその他の改変を加えたオレアノール酸誘導体
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US8981144B2 (en)	2012-05-08	2015-03-17	Trustees Of Dartmouth College	Method for synthesizing 2-cyano-3,12-dioxoolean-1, 9(11)-dien-28-oic acid methyl ester and derivatives thereof
US8921419B2 (en)	2012-05-08	2014-12-30	Trustees Of Dartmouth College	Triterpenoids and compositions containing the same
US9556222B2 (en)	2012-06-15	2017-01-31	Reata Pharmaceuticals, Inc.	A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof
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UY39092A (es)	2013-04-24	2021-03-26	Abbvie Inc	Derivados de 2,2-difluoropropanamida y metil bardoxolona, formas polimórficas y métodos de uso
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US10189791B2 (en)	2014-08-26	2019-01-29	Trustees Of Dartmouth College	Pyridyl analogs of 1-(2-cyano-3,12-dioxooleana-1,9(11)dien-28-oyl) imidazole
US9896475B2 (en)	2014-08-26	2018-02-20	Trustees Of Dartmouth College	Pyridyl analogs of 1-(2-cyano-3,12-dioxooleana-1,9(11)dien-28-oyl) imidazole
EP3192875B1 (fr)	2014-09-10	2019-12-18	Daiichi Sankyo Company, Limited	Composition pharmaceutique à libération prolongée destinée au traitement et à la prévention de maladies ophtalmiques
WO2016089648A1 (fr)	2014-12-01	2016-06-09	Vtv Therapeutics Llc	Inhibiteurs de bach1 en combinaison avec des activateurs de nrf2 et compositions pharmaceutiques les contenant
US11591302B2 (en)	2014-12-19	2023-02-28	Geistlich Pharm A Ag	Processes for preparing oxathiazin-like compounds
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CN107428698B (zh)	2015-02-12	2021-10-26	里亚塔医药公司	作为抗氧化炎症调节剂的咪唑基三环烯酮
PL3317281T3 (pl) *	2015-07-02	2020-11-02	Acerta Pharma B.V.	Postacie stałe i formulacje (s)-4-(8-amino-3-(1-(but-2-ynoilo)pirolidyn-2-ylo)imidazo[1,5-a]-pirazyn-1-ylo)-n-(pirydyn-2-ylo)benzamidu
NZ741082A (en)	2015-09-23	2023-06-30	Reata Pharmaceuticals Inc	C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses
NZ753546A (en) *	2016-11-08	2022-10-28	Reata Pharmaceuticals Holdings Llc	Methods of treating alport syndrome using bardoxolone methyl or analogs thereof
TWI831738B (zh)	2016-12-16	2024-02-11	美商瑞塔醫藥有限責任公司	用於抑制ＲＯＲγ及其他用途的嘧啶三環烯酮衍生物
EP3652193A1 (fr)	2017-07-13	2020-05-20	Pliva Hrvatska D.O.O.	Nouvelles formes polymorphes cristallines du bardoxolone méthyle
JP7244536B2 (ja)	2018-04-06	2023-03-22	キャプシュゲル・ベルジウム・エヌ・ヴィ	メタクリル酸メチル－メタクリル酸コポリマーからなる低アスペクト比の粒子のための噴霧乾燥方法
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2008
- 2008-08-13 US US12/191,176 patent/US8088824B2/en active Active
- 2008-08-14 WO PCT/US2008/009703 patent/WO2009023232A1/fr not_active Ceased
- 2008-08-14 SI SI200830650T patent/SI2187741T1/sl unknown
- 2008-08-14 EP EP12153605.6A patent/EP2450057B1/fr active Active
- 2008-08-14 EP EP08795303A patent/EP2187741B1/fr active Active
- 2008-08-14 CA CA2871864A patent/CA2871864C/fr active Active
- 2008-08-14 HU HUE12153605A patent/HUE031866T2/en unknown
- 2008-08-14 NZ NZ583269A patent/NZ583269A/en unknown
- 2008-08-14 MX MX2010001628A patent/MX2010001628A/es active IP Right Grant
- 2008-08-14 PL PL08795303T patent/PL2187741T3/pl unknown
- 2008-08-14 DK DK08795303.0T patent/DK2187741T3/da active
- 2008-08-14 HR HRP20120350AT patent/HRP20120350T1/hr unknown
- 2008-08-14 AU AU2008287388A patent/AU2008287388B2/en active Active
- 2008-08-14 KR KR1020107005094A patent/KR101481764B1/ko active Active
- 2008-08-14 DK DK12153605.6T patent/DK2450057T3/en active
- 2008-08-14 SG SG2011094158A patent/SG177905A1/en unknown
- 2008-08-14 PT PT121536056T patent/PT2450057T/pt unknown
- 2008-08-14 KR KR1020147002848A patent/KR101544766B1/ko active Active
- 2008-08-14 EA EA201070149A patent/EA018704B1/ru unknown
- 2008-08-14 ES ES08795303T patent/ES2382571T3/es active Active
- 2008-08-14 AT AT08795303T patent/ATE549035T1/de active
- 2008-08-14 TW TW102134576A patent/TWI486357B/zh active
- 2008-08-14 JP JP2010521031A patent/JP5005812B2/ja active Active
- 2008-08-14 PL PL12153605T patent/PL2450057T3/pl unknown
- 2008-08-14 CN CN2008801112346A patent/CN101820758B/zh active Active
- 2008-08-14 CL CL2008002417A patent/CL2008002417A1/es unknown
- 2008-08-14 CN CN201310016448.8A patent/CN103254267B/zh active Active
- 2008-08-14 PT PT08795303T patent/PT2187741E/pt unknown
- 2008-08-14 SG SG10201504650VA patent/SG10201504650VA/en unknown
- 2008-08-14 CA CA2696330A patent/CA2696330C/fr active Active
- 2008-08-14 TW TW097130947A patent/TWI419899B/zh active
- 2008-08-14 AR ARP080103557A patent/AR073155A1/es unknown
- 2008-08-14 BR BRPI0815540A patent/BRPI0815540A8/pt not_active Application Discontinuation
- 2008-08-14 SI SI200831728A patent/SI2450057T1/sl unknown
- 2008-08-14 EA EA201370109A patent/EA023550B1/ru unknown
- 2008-08-14 ES ES12153605.6T patent/ES2602978T3/es active Active
- 2008-08-14 LT LTEP12153605.6T patent/LT2450057T/lt unknown
2010
- 2010-02-09 IL IL203824A patent/IL203824A/en active IP Right Grant
- 2010-02-12 ZA ZA201001066A patent/ZA201001066B/xx unknown
2011
- 2011-11-29 US US13/306,043 patent/US8309601B2/en active Active
2012
- 2012-05-23 JP JP2012117773A patent/JP2012188438A/ja active Pending
- 2012-06-13 CY CY20121100542T patent/CY1112864T1/el unknown
- 2012-06-29 US US13/537,583 patent/US8633243B2/en active Active
2015
- 2015-05-07 JP JP2015094538A patent/JP2015164939A/ja active Pending
2016
- 2016-11-15 HR HRP20161503TT patent/HRP20161503T1/hr unknown
- 2016-11-23 CY CY20161101205T patent/CY1118329T1/el unknown
2017
- 2017-03-27 IL IL251419A patent/IL251419A0/en unknown
- 2017-08-10 JP JP2017154939A patent/JP2018009001A/ja active Pending
2020
- 2020-03-25 AR ARP200100825A patent/AR119704A2/es unknown

Also Published As

Publication number	Publication date
US8088824B2 (en)	2012-01-03
AU2008287388A1 (en)	2009-02-19
JP2018009001A (ja)	2018-01-18
EA023550B1 (ru)	2016-06-30
EA018704B1 (ru)	2013-10-30
CN103254267A (zh)	2013-08-21
US20120071684A1 (en)	2012-03-22
PL2450057T3 (pl)	2017-02-28
SI2187741T1 (sl)	2012-07-31
IL251419A0 (en)	2017-05-29
ES2602978T3 (es)	2017-02-23
PT2187741E (pt)	2012-06-21
PT2450057T (pt)	2016-12-15
WO2009023232A1 (fr)	2009-02-19
EA201370109A1 (ru)	2014-01-30
TW201402597A (zh)	2014-01-16
ES2382571T3 (es)	2012-06-11
CY1112864T1 (el)	2016-04-13
CA2871864A1 (fr)	2009-02-19
TW200916476A (en)	2009-04-16
KR101544766B1 (ko)	2015-08-17
HUE031866T2 (en)	2017-08-28
JP5005812B2 (ja)	2012-08-22
SG177905A1 (en)	2012-02-28
BRPI0815540A2 (pt)	2014-09-30
AR073155A1 (es)	2010-10-20
CN101820758A (zh)	2010-09-01
EP2187741A1 (fr)	2010-05-26
JP2012188438A (ja)	2012-10-04
JP2015164939A (ja)	2015-09-17
IL203824A (en)	2017-04-30
KR20140024063A (ko)	2014-02-27
CA2696330C (fr)	2015-03-24
BRPI0815540A8 (pt)	2023-04-11
MX2010001628A (es)	2010-06-02
LT2450057T (lt)	2016-12-27
PL2187741T3 (pl)	2012-08-31
CA2696330A1 (fr)	2009-02-19
DK2187741T3 (da)	2012-04-16
SI2450057T1 (sl)	2017-01-31
CN101820758B (zh)	2013-03-06
DK2450057T3 (en)	2016-12-19
HRP20120350T1 (hr)	2012-05-31
TWI486357B (zh)	2015-06-01
HK1143537A1 (en)	2011-01-07
KR20100056488A (ko)	2010-05-27
CA2871864C (fr)	2016-05-17
AR119704A2 (es)	2022-01-05
CN103254267B (zh)	2016-03-16
US20120330050A1 (en)	2012-12-27
US8633243B2 (en)	2014-01-21
AU2008287388B2 (en)	2014-11-06
CY1118329T1 (el)	2017-06-28
KR101481764B1 (ko)	2015-01-13
US20090048204A1 (en)	2009-02-19
NZ583269A (en)	2012-03-30
EP2450057B1 (fr)	2016-09-28
TWI419899B (zh)	2013-12-21
SG10201504650VA (en)	2015-07-30
EP2187741B1 (fr)	2012-03-14
EA201070149A1 (ru)	2010-08-30
EP2450057A1 (fr)	2012-05-09
HRP20161503T1 (hr)	2017-01-13
ATE549035T1 (de)	2012-03-15
EP2187741A4 (fr)	2010-08-25
CL2008002417A1 (es)	2009-03-27
US8309601B2 (en)	2012-11-13
JP2010536754A (ja)	2010-12-02

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