ZA200903129B - Improvements in an relating to drive mechanisms suitable for use in drug delivery devices - Google Patents

Improvements in an relating to drive mechanisms suitable for use in drug delivery devices

Info

Publication number: ZA200903129B
Authority: ZA; South Africa
Prior art keywords: relating; drug delivery; delivery devices; drive mechanisms; mechanisms suitable
Prior art date: 2006-11-17

Application number

ZA200903129A

Other languages

English (en)

Inventor

Malcom Boyd

Richard Letham

David Plumptre

Robert Veasey

James May

Matthew Ghazaros Jones

Samuel Llewhelin Ghazaros

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-11-17

Filing date

2009-05-06

Publication date

2010-03-31

2009-05-06 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2010-03-31 Publication of ZA200903129B publication Critical patent/ZA200903129B/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3104—Caps for syringes without needle
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49826—Assembling or joining

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Life Sciences & Earth Sciences (AREA)
Vascular Medicine (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Transmission Devices (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Catching Or Destruction (AREA)

ZA200903129A 2006-11-17 2009-05-06 Improvements in an relating to drive mechanisms suitable for use in drug delivery devices ZA200903129B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP20060023951 EP1923083A1 (en)	2006-11-17	2006-11-17	Drive mechanisms for use in drug delivery devices

Publications (1)

Publication Number	Publication Date
ZA200903129B true ZA200903129B (en)	2010-03-31

Family

ID=37845160

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ZA200903077A ZA200903077B (en)	2006-11-17	2009-05-05	Improvements in and relating to drive mechanisms suitable for use in drug delivery devices
ZA200903129A ZA200903129B (en)	2006-11-17	2009-05-06	Improvements in an relating to drive mechanisms suitable for use in drug delivery devices

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ZA200903077A ZA200903077B (en)	2006-11-17	2009-05-05	Improvements in and relating to drive mechanisms suitable for use in drug delivery devices

Country Status (39)

Country	Link
US (4)	US7993301B2 (xx)
EP (4)	EP1923083A1 (xx)
JP (2)	JP5286275B2 (xx)
KR (2)	KR101422056B1 (xx)
CN (2)	CN101622023B (xx)
AR (2)	AR063830A1 (xx)
AU (2)	AU2007321449B2 (xx)
BR (2)	BRPI0719070A2 (xx)
CA (2)	CA2669379C (xx)
CL (2)	CL2007003300A1 (xx)
CO (2)	CO6210736A2 (xx)
CR (2)	CR10769A (xx)
CY (1)	CY1113800T1 (xx)
DK (2)	DK2091599T3 (xx)
EC (2)	ECSP099333A (xx)
EG (1)	EG25189A (xx)
ES (1)	ES2401354T3 (xx)
GT (2)	GT200900131A (xx)
HN (2)	HN2009001000A (xx)
IL (2)	IL198747A (xx)
MA (2)	MA30884B1 (xx)
ME (1)	ME00589A (xx)
MX (2)	MX2009005093A (xx)
MY (2)	MY149575A (xx)
NI (2)	NI200900087A (xx)
NO (2)	NO20092324L (xx)
NZ (2)	NZ576964A (xx)
PE (2)	PE20081204A1 (xx)
PL (1)	PL2091599T3 (xx)
PT (1)	PT2091599E (xx)
RU (2)	RU2452521C2 (xx)
SI (1)	SI2091599T1 (xx)
SV (2)	SV2009003263A (xx)
TN (2)	TN2009000188A1 (xx)
TW (2)	TW200833387A (xx)
UA (2)	UA96167C2 (xx)
UY (2)	UY30721A1 (xx)
WO (2)	WO2008058668A1 (xx)
ZA (2)	ZA200903077B (xx)

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EP2196233A1 (en)	2008-12-12	2010-06-16	Sanofi-Aventis Deutschland GmbH	Resettable drive mechanism for a medication delivery device and medication delivery device
EP2198904A1 (en) *	2008-12-19	2010-06-23	Sanofi-Aventis Deutschland GmbH	Interlock mechanism for a drug delivery device and drug delivery device
EP2201971A1 (en) *	2008-12-23	2010-06-30	Sanofi-Aventis Deutschland GmbH	Drug delivery device
EP2201974A1 (en)	2008-12-23	2010-06-30	Sanofi-Aventis Deutschland GmbH	Medication delivery device
JP5687214B2 (ja)	2009-03-05	2015-03-18	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	薬物送達デバイス
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BRPI1012730A2 (pt)	2009-03-31	2016-05-03	Sanofi Aventis Deutschland	dispositivo de distribuição de fármaco
JP5787875B2 (ja)	2009-03-31	2015-09-30	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	機構を有する医療デバイス及び医療デバイス内における低摩擦合成材料の使用
JP5703287B2 (ja)	2009-03-31	2015-04-15	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	接着剤を使用する薬物送達デバイス本体の製造方法及び薬物送達デバイス本体
US9555194B2 (en)	2009-03-31	2017-01-31	Sanofi-Aventis Deutschalnd Gmbh	Drug delivery device
US9474861B2 (en)	2009-03-31	2016-10-25	Sanofi-Aventis Deutschland Gmbh	Drug delivery device body
WO2010112376A1 (en) *	2009-03-31	2010-10-07	Sanofi-Aventis Deutschland Gmbh	Improvements in and relating to medicament delivery devices
EP2414011B1 (en)	2009-04-01	2016-04-27	SHL Group AB	Medicament delivery device
CA2760759A1 (en)	2009-05-20	2010-11-25	Sanofi-Aventis Deutschland Gmbh	Drug delivery device and use of a rotatable roll in a drug delivery device
EP2292286A1 (en) *	2009-09-07	2011-03-09	Sanofi-Aventis Deutschland GmbH	Drive mechanism for a medication delivery device and medication delivery device
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TW201127434A (en)	2009-09-30	2011-08-16	Sanofi Aventis Deutschland	Drug delivery device
TW201121602A (en)	2009-09-30	2011-07-01	Sanofi Aventis Deutschland	Drive assembly, piston rod, drug delivery device, and use of a spring
JP5768051B2 (ja)	2009-09-30	2015-08-26	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	薬物送達デバイス及び薬物送達デバイスのための駆動部材
DK2482889T3 (en) *	2009-09-30	2016-05-17	Sanofi Aventis Deutschland	ACCOMMODATION drug delivery device
TW201127435A (en) *	2009-09-30	2011-08-16	Sanofi Aventis Deutschland	Drive mechanism for a drug delivery device
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2009
- 2009-05-05 ZA ZA200903077A patent/ZA200903077B/xx unknown
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- 2009-05-06 ZA ZA200903129A patent/ZA200903129B/xx unknown
- 2009-05-12 MA MA31865A patent/MA30884B1/fr unknown
- 2009-05-12 MA MA31866A patent/MA30885B1/fr unknown
- 2009-05-13 CO CO09048548A patent/CO6210736A2/es active IP Right Grant
- 2009-05-13 CO CO09048547A patent/CO6210737A2/es active IP Right Grant
- 2009-05-14 NI NI200900087A patent/NI200900087A/es unknown
- 2009-05-14 IL IL198747A patent/IL198747A/en not_active IP Right Cessation
- 2009-05-14 IL IL198750A patent/IL198750A/en not_active IP Right Cessation
- 2009-05-14 EG EG2009050713A patent/EG25189A/xx active
- 2009-05-15 TN TNP2009000188A patent/TN2009000188A1/fr unknown
- 2009-05-15 HN HN2009001000A patent/HN2009001000A/es unknown
- 2009-05-15 US US12/466,596 patent/US7993301B2/en active Active
- 2009-05-15 EC ECSP099333 patent/ECSP099333A/es unknown
- 2009-05-15 GT GT200900131A patent/GT200900131A/es unknown
- 2009-05-15 TN TNP2009000192A patent/TN2009000192A1/fr unknown
- 2009-05-15 US US12/466,586 patent/US8167849B2/en active Active
- 2009-05-15 SV SV2009003263A patent/SV2009003263A/es unknown
- 2009-05-15 HN HN2009000998A patent/HN2009000998A/es unknown
- 2009-05-15 SV SV2009003264A patent/SV2009003264A/es unknown
- 2009-05-15 GT GT200900132A patent/GT200900132A/es unknown
- 2009-05-15 EC ECSP099334 patent/ECSP099334A/es unknown
- 2009-05-28 NI NI200900105A patent/NI200900105A/es unknown
- 2009-06-16 NO NO20092324A patent/NO20092324L/no not_active Application Discontinuation
- 2009-06-16 NO NO20092322A patent/NO20092322L/no not_active Application Discontinuation
2011
- 2011-06-30 US US13/173,445 patent/US8771239B2/en active Active
2012
- 2012-01-10 US US13/347,399 patent/US9078976B2/en active Active
2013
- 2013-03-13 CY CY20131100219T patent/CY1113800T1/el unknown

Also Published As

Publication number	Publication date
MA30884B1 (fr)	2009-11-02
CN101610804A (zh)	2009-12-23
AR063830A1 (es)	2009-02-18
CR10770A (es)	2009-07-23
TN2009000188A1 (en)	2010-10-18
JP2010522577A (ja)	2010-07-08
CR10769A (es)	2009-05-25
WO2008058668A1 (en)	2008-05-22
KR20090082489A (ko)	2009-07-30
CY1113800T1 (el)	2016-07-27
US8167849B2 (en)	2012-05-01
IL198750A0 (en)	2010-02-17
CO6210737A2 (es)	2010-10-20
CA2669374A1 (en)	2008-05-22
CN101622023A (zh)	2010-01-06
EP2392372A3 (en)	2012-03-07
CA2669379C (en)	2014-12-30
HK1140436A1 (en)	2010-10-15
TW200833383A (en)	2008-08-16
HK1140154A1 (en)	2010-10-08
ES2401354T3 (es)	2013-04-18
HN2009000998A (es)	2011-10-12
AU2007321447B9 (en)	2013-02-28
CO6210736A2 (es)	2010-10-20
RU2009123008A (ru)	2010-12-27
TN2009000192A1 (en)	2010-10-18
CN101622023B (zh)	2013-04-24
TW200833387A (en)	2008-08-16
KR101422056B1 (ko)	2014-07-23
CA2669374C (en)	2015-03-31
DK2091599T3 (da)	2013-03-25
JP2010509958A (ja)	2010-04-02
EP2091599B1 (en)	2012-12-26
ECSP099334A (es)	2009-06-30
US7993301B2 (en)	2011-08-09
BRPI0719070A2 (pt)	2014-08-12
IL198747A (en)	2012-12-31
MX2009005007A (es)	2009-05-20
US20120172816A1 (en)	2012-07-05
AU2007321449B2 (en)	2013-08-22
ECSP099333A (es)	2009-06-30
GT200900132A (es)	2011-08-08
UA97260C2 (ru)	2012-01-25
NZ577007A (en)	2011-05-27
NO20092324L (no)	2009-08-12
EP2081622B1 (en)	2016-01-06
SV2009003263A (es)	2009-10-27
KR20090080560A (ko)	2009-07-24
US9078976B2 (en)	2015-07-14
GT200900131A (es)	2011-05-25
RU2009122952A (ru)	2010-12-27
NI200900087A (es)	2010-01-29
AR063836A1 (es)	2009-02-25
MX2009005093A (es)	2009-05-27
AU2007321447B2 (en)	2013-02-21
RU2460546C2 (ru)	2012-09-10
BRPI0719069A2 (pt)	2013-12-03
MY148971A (en)	2013-06-28
US20100094207A1 (en)	2010-04-15
CA2669379A1 (en)	2008-05-22
IL198750A (en)	2012-10-31
PE20081204A1 (es)	2008-09-29
CL2007003300A1 (es)	2008-06-27
HN2009001000A (es)	2012-09-21
JP5286275B2 (ja)	2013-09-11
IL198747A0 (en)	2010-02-17
ME00589A (en)	2011-12-20
NO20092322L (no)	2009-08-10
AU2007321449A1 (en)	2008-05-22
PL2091599T3 (pl)	2013-07-31
UA96167C2 (ru)	2011-10-10
US8771239B2 (en)	2014-07-08
AU2007321447A1 (en)	2008-05-22
ZA200903077B (en)	2010-04-28
EP2081622A1 (en)	2009-07-29
TWI487544B (zh)	2015-06-11
KR101422459B1 (ko)	2014-07-23
US20100094206A1 (en)	2010-04-15
PE20081203A1 (es)	2008-09-24
JP5427607B2 (ja)	2014-02-26
EP2392372A2 (en)	2011-12-07
UY30722A1 (es)	2008-07-03
PT2091599E (pt)	2013-03-05
NI200900105A (es)	2010-01-29
MA30885B1 (fr)	2009-11-02
US20120289929A1 (en)	2012-11-15
SI2091599T1 (sl)	2013-04-30
RU2452521C2 (ru)	2012-06-10
EP1923083A1 (en)	2008-05-21
WO2008058666A1 (en)	2008-05-22
CN101610804B (zh)	2012-12-12
MY149575A (en)	2013-09-13
EP2091599A1 (en)	2009-08-26
DK2081622T3 (en)	2016-04-11
NZ576964A (en)	2011-05-27
CL2007003301A1 (es)	2008-06-27
UY30721A1 (es)	2008-07-03
SV2009003264A (es)	2009-10-27
EG25189A (en)	2011-10-17

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