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ZA200810460B - Modified beta-lactamase and method for its preparation - Google Patents

Modified beta-lactamase and method for its preparation

Info

Publication number
ZA200810460B
ZA200810460B ZA200810460A ZA200810460A ZA200810460B ZA 200810460 B ZA200810460 B ZA 200810460B ZA 200810460 A ZA200810460 A ZA 200810460A ZA 200810460 A ZA200810460 A ZA 200810460A ZA 200810460 B ZA200810460 B ZA 200810460B
Authority
ZA
South Africa
Prior art keywords
lactamase
preparation
modified beta
beta
modified
Prior art date
Application number
ZA200810460A
Other languages
English (en)
Inventor
Susanna Kaeaeriaeinen
Nina Wickstrand
Pertti Koski
Original Assignee
Ipsat Therapies Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsat Therapies Oy filed Critical Ipsat Therapies Oy
Publication of ZA200810460B publication Critical patent/ZA200810460B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA200810460A 2006-06-21 2008-12-10 Modified beta-lactamase and method for its preparation ZA200810460B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20065431A FI119190B (fi) 2006-06-21 2006-06-21 Modifioitu beta-laktamaasi ja menetelmä sen valmistamiseksi

Publications (1)

Publication Number Publication Date
ZA200810460B true ZA200810460B (en) 2009-12-30

Family

ID=36651526

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200810460A ZA200810460B (en) 2006-06-21 2008-12-10 Modified beta-lactamase and method for its preparation

Country Status (15)

Country Link
US (1) US7989192B2 (xx)
EP (1) EP2038411B1 (xx)
JP (1) JP5306191B2 (xx)
KR (1) KR101609243B1 (xx)
CN (1) CN101484577A (xx)
AU (1) AU2007262916B2 (xx)
BR (1) BRPI0713726B1 (xx)
CA (1) CA2659691C (xx)
ES (1) ES2452321T3 (xx)
FI (1) FI119190B (xx)
NO (1) NO342006B1 (xx)
NZ (1) NZ573696A (xx)
RU (1) RU2009101795A (xx)
WO (1) WO2007147945A1 (xx)
ZA (1) ZA200810460B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20105572A0 (fi) 2010-05-24 2010-05-24 Prevab R Lcc Muokattu beeta-laktamaasi ja siihen liittyvät menetelmät ja käytöt
AU2011268310A1 (en) * 2010-06-16 2013-01-10 Abbvie Inc. Comparison of protein samples
TW201239355A (en) 2011-03-23 2012-10-01 Abbott Lab Methods and systems for the analysis of protein samples
EP3156496B1 (fr) * 2011-04-21 2019-04-10 Biomérieux Inc. Procede de detection d'au moins un mecanisme de resistance aux cephalosporines par spectrometrie de masse
CN106163546B (zh) 2014-04-17 2021-02-19 合成生物制品有限公司 具有改进的治疗性质的β-内酰胺酶
EP3186379B1 (en) 2014-08-28 2020-04-08 Synthetic Biologics, Inc. E. coli-based production of beta-lactamase
EP3204495B1 (en) 2014-10-08 2020-04-22 Synthetic Biologics, Inc. Beta-lactamase formulations and uses thereof
FR3027307B1 (fr) 2014-10-16 2016-11-04 Azurrx Sas Molecule proteique hybride apte a inhiber au moins un antibiotique et composition pharmaceutique la comportant
EP3236993B1 (en) 2014-12-23 2023-09-13 Theriva Biologics, Inc. Methods and compositions for inhibiting or preventing adverse effects of oral antibiotics
JP6810697B2 (ja) 2015-02-23 2021-01-13 シンセティック・バイオロジクス・インコーポレイテッド 腸内マイクロバイオームの保護のために抗生物質と共に使用するカルバペネマーゼ
WO2016144856A1 (en) 2015-03-06 2016-09-15 Synthetic Biologics, Inc. Safe and effective beta-lactamase dosing for microbiome protection
US10988749B2 (en) 2016-02-23 2021-04-27 Da Volterra Beta-lactamase variants
KR20180110032A (ko) * 2016-02-23 2018-10-08 다 볼떼라 베타-락타마제 변이체
KR20210040395A (ko) 2018-08-05 2021-04-13 다 볼떼라 이식편 대 숙주 질환의 치료를 위한 조성물
US20210299170A1 (en) 2018-08-05 2021-09-30 Da Volterra Method for improving anticancer agent efficacy
US20220154156A1 (en) * 2019-03-11 2022-05-19 Regents Of The University Of Minnesota Proteins and methods for disrupting bacterial communication
CN115104030B (zh) * 2019-12-30 2025-11-21 希真医疗财团 碳青霉烯类抗生素耐药病原菌株的直接检测方法
EP4148136A1 (en) 2021-09-08 2023-03-15 Da Volterra An engineered yeast cell for the delivery of antibiotic-inactivating enzymes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI920206A0 (fi) 1992-01-17 1992-01-17 Pekka Untamo Heino Medicinsk anvaendning, medicinskt foerfarande och preparat.
FI112666B (fi) * 2001-11-06 2003-12-31 Ipsat Therapies Oy Itiöimätön Bacillus subtilis, sen valmistus ja käyttö
FR2843302B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs

Also Published As

Publication number Publication date
EP2038411A1 (en) 2009-03-25
FI20065431A0 (fi) 2006-06-21
BRPI0713726A2 (pt) 2012-10-30
ES2452321T3 (es) 2014-03-31
FI119190B (fi) 2008-08-29
JP2009540814A (ja) 2009-11-26
KR101609243B1 (ko) 2016-04-05
WO2007147945A1 (en) 2007-12-27
NO342006B1 (no) 2018-03-12
NO20090297L (no) 2009-01-19
KR20090046787A (ko) 2009-05-11
US7989192B2 (en) 2011-08-02
WO2007147945A8 (en) 2009-07-30
NZ573696A (en) 2011-09-30
US20090181004A1 (en) 2009-07-16
CA2659691C (en) 2015-05-19
EP2038411A4 (en) 2010-04-07
RU2009101795A (ru) 2010-07-27
CA2659691A1 (en) 2007-12-27
AU2007262916B2 (en) 2013-12-05
AU2007262916A1 (en) 2007-12-27
FI20065431L (fi) 2007-12-22
CN101484577A (zh) 2009-07-15
EP2038411B1 (en) 2014-02-26
BRPI0713726B1 (pt) 2023-01-10
JP5306191B2 (ja) 2013-10-02

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