ZA200806496B - Drug delivery systems comprising weakly basic drugs and organic acids - Google Patents
Drug delivery systems comprising weakly basic drugs and organic acidsInfo
- Publication number
- ZA200806496B ZA200806496B ZA200806496A ZA200806496A ZA200806496B ZA 200806496 B ZA200806496 B ZA 200806496B ZA 200806496 A ZA200806496 A ZA 200806496A ZA 200806496 A ZA200806496 A ZA 200806496A ZA 200806496 B ZA200806496 B ZA 200806496B
- Authority
- ZA
- South Africa
- Prior art keywords
- drug delivery
- organic acids
- delivery systems
- weakly basic
- basic drugs
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 238000012377 drug delivery Methods 0.000 title 1
- 150000007524 organic acids Chemical class 0.000 title 1
- 235000005985 organic acids Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76276606P | 2006-01-27 | 2006-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200806496B true ZA200806496B (en) | 2009-12-30 |
Family
ID=38326503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200806496A ZA200806496B (en) | 2006-01-27 | 2007-01-29 | Drug delivery systems comprising weakly basic drugs and organic acids |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20070196491A1 (xx) |
| EP (2) | EP2387994A1 (xx) |
| JP (2) | JP5787301B2 (xx) |
| KR (2) | KR20140088230A (xx) |
| CN (1) | CN101410093A (xx) |
| AU (1) | AU2007211101B2 (xx) |
| BR (1) | BRPI0707325A2 (xx) |
| CA (1) | CA2640382C (xx) |
| ES (1) | ES2533563T5 (xx) |
| IL (1) | IL193019A0 (xx) |
| NZ (1) | NZ569984A (xx) |
| RU (2) | RU2428176C2 (xx) |
| WO (1) | WO2007090091A2 (xx) |
| ZA (1) | ZA200806496B (xx) |
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| AR036741A1 (es) * | 2001-10-05 | 2004-09-29 | Combinatorx Inc | Combinaciones para el tratamiento de los trastornos inmunoinflamatorios |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| EP1912650B8 (en) | 2005-08-03 | 2017-10-18 | Sprout Pharmaceuticals, Inc. | Use of flibanserin in the treatment of obesity |
| EP1945214A1 (en) | 2005-10-29 | 2008-07-23 | Boehringer Ingelheim International GmbH | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| CA2652773A1 (en) * | 2006-05-22 | 2007-12-06 | Combinatorx, Incorporated | Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels |
| DE602007004615D1 (de) | 2006-06-30 | 2010-03-18 | Boehringer Ingelheim Pharma | Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| BRPI0716439B8 (pt) | 2006-08-14 | 2021-05-25 | Boehringer Ingelheim Int | sistemas de liberação farmacêutico compreendendo flibanserina, processo para preparação e uso dos mesmos |
| JP5220746B2 (ja) * | 2006-08-25 | 2013-06-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 制御放出システム及びその製造方法 |
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| CN102036654B (zh) * | 2008-07-24 | 2014-05-14 | 湖南洞庭药业股份有限公司 | 稳定的非典型抗精神病制剂 |
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| CN109864971B (zh) * | 2019-04-08 | 2021-12-17 | 西安远大德天药业股份有限公司 | 一种拉莫三嗪固体分散体的颗粒剂及其制备方法 |
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-
2007
- 2007-01-29 JP JP2008552613A patent/JP5787301B2/ja not_active Expired - Fee Related
- 2007-01-29 CN CNA2007800114068A patent/CN101410093A/zh active Pending
- 2007-01-29 EP EP11001815A patent/EP2387994A1/en not_active Withdrawn
- 2007-01-29 WO PCT/US2007/061237 patent/WO2007090091A2/en not_active Ceased
- 2007-01-29 ZA ZA200806496A patent/ZA200806496B/xx unknown
- 2007-01-29 NZ NZ569984A patent/NZ569984A/en not_active IP Right Cessation
- 2007-01-29 KR KR1020147016956A patent/KR20140088230A/ko not_active Ceased
- 2007-01-29 EP EP07717476.1A patent/EP1976492B8/en not_active Not-in-force
- 2007-01-29 CA CA2640382A patent/CA2640382C/en not_active Expired - Fee Related
- 2007-01-29 ES ES07717476.1T patent/ES2533563T5/es active Active
- 2007-01-29 KR KR20087021035A patent/KR101489401B1/ko not_active Expired - Fee Related
- 2007-01-29 RU RU2008134900/15A patent/RU2428176C2/ru not_active IP Right Cessation
- 2007-01-29 BR BRPI0707325-9A patent/BRPI0707325A2/pt not_active IP Right Cessation
- 2007-01-29 AU AU2007211101A patent/AU2007211101B2/en not_active Ceased
- 2007-01-29 US US11/668,408 patent/US20070196491A1/en not_active Abandoned
-
2008
- 2008-07-24 IL IL193019A patent/IL193019A0/en not_active IP Right Cessation
-
2011
- 2011-05-13 RU RU2011119504/15A patent/RU2011119504A/ru not_active Application Discontinuation
-
2013
- 2013-05-29 JP JP2013113203A patent/JP2013189455A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| RU2008134900A (ru) | 2010-03-10 |
| ES2533563T3 (es) | 2015-04-13 |
| EP1976492B2 (en) | 2018-05-16 |
| RU2011119504A (ru) | 2012-11-20 |
| US20070196491A1 (en) | 2007-08-23 |
| EP1976492B1 (en) | 2015-01-21 |
| KR20080104132A (ko) | 2008-12-01 |
| CA2640382C (en) | 2015-12-29 |
| ES2533563T5 (es) | 2018-07-24 |
| JP5787301B2 (ja) | 2015-09-30 |
| RU2428176C2 (ru) | 2011-09-10 |
| JP2009524698A (ja) | 2009-07-02 |
| CN101410093A (zh) | 2009-04-15 |
| CA2640382A1 (en) | 2007-08-09 |
| EP1976492B8 (en) | 2018-07-04 |
| NZ569984A (en) | 2011-06-30 |
| WO2007090091A3 (en) | 2007-11-22 |
| AU2007211101A1 (en) | 2007-08-09 |
| JP2013189455A (ja) | 2013-09-26 |
| IL193019A0 (en) | 2009-08-03 |
| KR20140088230A (ko) | 2014-07-09 |
| BRPI0707325A2 (pt) | 2011-05-03 |
| WO2007090091A2 (en) | 2007-08-09 |
| EP1976492A2 (en) | 2008-10-08 |
| EP2387994A1 (en) | 2011-11-23 |
| AU2007211101B2 (en) | 2013-05-02 |
| KR101489401B1 (ko) | 2015-02-03 |
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