ZA200806358B - Triazole Derivatives - Google Patents

Triazole Derivatives

Info

Publication number: ZA200806358B
Authority: ZA; South Africa
Prior art keywords: triazole derivatives; triazole; derivatives
Prior art date: 2005-12-23

Application number

ZA200806358A

Other languages

English (en)

Inventor

Bertram Cezanne

Christiane Amendt

Hartmut Greiner

Ulrich Graedler

Guenter Hoelzemann

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-23

Filing date

2008-07-22

Publication date

2009-12-30

2008-07-22 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2009-12-30 Publication of ZA200806358B publication Critical patent/ZA200806358B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Virology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Communicable Diseases (AREA)
Hospice & Palliative Care (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Psychiatry (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

ZA200806358A 2005-12-23 2008-07-22 Triazole Derivatives ZA200806358B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE102005061840A DE102005061840A1 (de)	2005-12-23	2005-12-23	Triazolderivate

Publications (1)

Publication Number	Publication Date
ZA200806358B true ZA200806358B (en)	2009-12-30

Family

ID=37973842

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200806358A ZA200806358B (en)	2005-12-23	2008-07-22	Triazole Derivatives

Country Status (15)

Country	Link
US (1)	US8093240B2 (xx)
EP (2)	EP1966211B1 (xx)
JP (1)	JP5236490B2 (xx)
KR (1)	KR20080090458A (xx)
CN (1)	CN101346383B (xx)
AR (1)	AR056860A1 (xx)
AU (1)	AU2006334899B2 (xx)
BR (1)	BRPI0620241A2 (xx)
CA (1)	CA2634553C (xx)
DE (1)	DE102005061840A1 (xx)
EA (1)	EA015254B1 (xx)
ES (1)	ES2400728T3 (xx)
IL (1)	IL192286A (xx)
WO (1)	WO2007079820A1 (xx)
ZA (1)	ZA200806358B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE102006051796A1 (de)	2006-11-03	2008-05-08	Merck Patent Gmbh	Triaza-benzo[e]azulenderivate
JP2011529456A (ja) *	2008-07-29	2011-12-08	メルクパテントゲゼルシャフトミットベシュレンクテルハフツング	イミダゾチアジアゾール誘導体
TW201103939A (en)	2009-03-31	2011-02-01	Arqule Inc	Substituted tetrahydropyrazolo-pyrido-azepine compounds
US8541407B2 (en)	2010-03-31	2013-09-24	Arqule, Inc.	Substituted benzo-pyrido-triazolo-diazepine compounds
US9249161B2 (en)	2010-12-02	2016-02-02	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
AR084070A1 (es)	2010-12-02	2013-04-17	Constellation Pharmaceuticals Inc	Inhibidores del bromodominio y usos de los mismos
US9422292B2 (en) *	2011-05-04	2016-08-23	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
WO2012174487A2 (en)	2011-06-17	2012-12-20	Constellation Pharmaceuticals, Inc.	Bromodomain inhibitors and uses thereof
US9624244B2 (en)	2012-06-06	2017-04-18	Constellation Pharmaceuticals, Inc.	Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (zh)	2012-06-06	2017-10-21	星宿藥物公司	溴域抑制劑及其用途
CA2952830C (en)	2014-06-20	2022-11-01	Constellation Pharmaceuticals, Inc.	Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide
CN106349241B (zh) *	2015-07-15	2020-04-21	上海翰森生物医药科技有限公司	具有hsp90抑制活性的三唑衍生物及其制备方法和应用
EP3458585A4 (en) *	2016-05-20	2019-10-30	President and Fellows of Harvard College	GENE THERAPY PROCEDURES FOR AGE-RELATED ILLNESSES AND SUFFERING
RU2711543C1 (ru) *	2019-02-20	2020-01-17	Общество С Ограниченной Ответственностью "Научно-Производственное Объединение "Фарматрон"	Способ лечения экспериментальных химических ожогов и катаракты, смоделированных на кроликах породы Шиншилла
CN110172068A (zh) *	2019-06-05	2019-08-27	河南龙湖生物技术有限公司	具有抗肿瘤活性的苯并噻唑类化合物及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE38931B1 (en)	1973-03-09	1978-07-05	Lipha	Triazolobenzodiazepines
DE2318673A1 (de) *	1973-04-13	1974-11-07	Boehringer Sohn Ingelheim	Neue substituierte triazolo-1,5benzodiazepine
US5747469A (en)	1991-03-06	1998-05-05	Board Of Regents, The University Of Texas System	Methods and compositions comprising DNA damaging agents and p53
FI925833A0 (fi) *	1991-04-23	1992-12-22	Toray Industries	Tricykliskt triazolderivat, dess framstaellning och dess anvaendning
GB9904387D0 (en)	1999-02-25	1999-04-21	Pharmacia & Upjohn Spa	Antitumour synergistic composition
EP1187633A4 (en)	1999-04-08	2005-05-11	Arch Dev Corp	USE OF ANTI-VEGF ANTIBODIES TO ENHANCE RADIATION IN ANTICANCER THERAPY
DK1397364T3 (da)	2001-05-24	2007-11-26	Lilly Co Eli	Hidtil ukendte pyrrolderivater som farmaceutiske midler
DE10131430A1 (de)	2001-06-29	2003-01-16	Bosch Gmbh Robert	Verfahren zum Verschweißen
GB0127430D0 (en) *	2001-11-15	2002-01-09	Smithkline Beecham Corp	Compounds
UA80296C2 (en)	2002-09-06	2007-09-10	Biogen Inc	Imidazolopyridines and methods of making and using the same
AU2003260810A1 (en)	2002-09-18	2004-04-08	Pfizer Products Inc.	Triazole derivatives as transforming growth factor (tgf) inhibitors
AU2003290734A1 (en) *	2002-11-27	2004-06-23	Eli Lilly And Company	Novel compounds as pharmaceutical agents

2005
- 2005-12-23 DE DE102005061840A patent/DE102005061840A1/de not_active Withdrawn
2006
- 2006-11-24 AU AU2006334899A patent/AU2006334899B2/en not_active Ceased
- 2006-11-24 EA EA200801430A patent/EA015254B1/ru not_active IP Right Cessation
- 2006-11-24 ES ES06818796T patent/ES2400728T3/es active Active
- 2006-11-24 BR BRPI0620241-1A patent/BRPI0620241A2/pt not_active IP Right Cessation
- 2006-11-24 KR KR1020087018192A patent/KR20080090458A/ko not_active Ceased
- 2006-11-24 CN CN2006800487919A patent/CN101346383B/zh not_active Expired - Fee Related
- 2006-11-24 US US12/158,344 patent/US8093240B2/en not_active Expired - Fee Related
- 2006-11-24 CA CA2634553A patent/CA2634553C/en not_active Expired - Fee Related
- 2006-11-24 WO PCT/EP2006/011277 patent/WO2007079820A1/de not_active Ceased
- 2006-11-24 JP JP2008546162A patent/JP5236490B2/ja not_active Expired - Fee Related
- 2006-11-24 EP EP06818796A patent/EP1966211B1/de not_active Not-in-force
- 2006-11-24 EP EP10014370A patent/EP2322527A1/de not_active Withdrawn
- 2006-12-20 AR ARP060105637A patent/AR056860A1/es unknown
2008
- 2008-06-18 IL IL192286A patent/IL192286A/en not_active IP Right Cessation
- 2008-07-22 ZA ZA200806358A patent/ZA200806358B/xx unknown

Also Published As

Publication number	Publication date
AR056860A1 (es)	2007-10-31
BRPI0620241A2 (pt)	2011-11-08
US8093240B2 (en)	2012-01-10
CN101346383B (zh)	2011-11-30
ES2400728T3 (es)	2013-04-11
AU2006334899B2 (en)	2012-06-07
KR20080090458A (ko)	2008-10-08
CA2634553A1 (en)	2007-07-19
JP5236490B2 (ja)	2013-07-17
US20080306042A1 (en)	2008-12-11
EA015254B1 (ru)	2011-06-30
IL192286A (en)	2012-10-31
EA200801430A1 (ru)	2008-12-30
AU2006334899A1 (en)	2007-07-19
DE102005061840A1 (de)	2007-06-28
EP1966211A1 (de)	2008-09-10
JP2009520706A (ja)	2009-05-28
IL192286A0 (en)	2008-12-29
WO2007079820A1 (de)	2007-07-19
CA2634553C (en)	2014-04-08
CN101346383A (zh)	2009-01-14
EP2322527A1 (de)	2011-05-18
EP1966211B1 (de)	2012-12-26
HK1128022A1 (en)	2009-10-16

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EP1942105A4 (en)	2011-06-15	AMINODIHYDROTHIAZINE DERIVATIVE
EP1847531A4 (en)	2009-04-22	PYRAZOLE DERIVATIVE
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EP1871766A4 (en)	2010-07-21	TRIAZONE DERIVATIVES WITH ANTIPILY EFFECT
ZA200804257B (en)	2009-04-29	Azaindole-2-carboxamide derivatives
PL1988083T3 (pl)	2014-08-29	Pochodna triazolowa
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IL192235A0 (en)	2009-02-11	Aryl-isoxazol-4-yl-imidazole derivatives
PL1954674T3 (pl)	2016-09-30	Nowe pochodne N-fenetylokarboksyamidu
IL191138A0 (en)	2008-12-29	Pyrazoloisoquinoline derivatives
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IL186107A0 (en)	2008-01-20	Pyridylmethylsulfone derivative
IL184559A0 (en)	2007-10-31	Imidazole derivatives
ZA200711025B (en)	2008-12-31	N-dihydroxyalkyl-substituted 2-oxoimidazole derivative
EP1951705A4 (en)	2010-12-15	NEW ANTIFUNGAL TRIAZOLE DERIVATIVES