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ZA200205566B - Cyclic quaternary ammonium compounds. - Google Patents

Cyclic quaternary ammonium compounds.

Info

Publication number
ZA200205566B
ZA200205566B ZA200205566A ZA200205566A ZA200205566B ZA 200205566 B ZA200205566 B ZA 200205566B ZA 200205566 A ZA200205566 A ZA 200205566A ZA 200205566 A ZA200205566 A ZA 200205566A ZA 200205566 B ZA200205566 B ZA 200205566B
Authority
ZA
South Africa
Prior art keywords
quaternary ammonium
ammonium compounds
cyclic quaternary
cyclic
compounds
Prior art date
Application number
ZA200205566A
Other languages
English (en)
Inventor
Lewis Liu Leung Choi
Clive P Page
Gregory N Beatch
Original Assignee
Ucb Farchim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Farchim Sa filed Critical Ucb Farchim Sa
Publication of ZA200205566B publication Critical patent/ZA200205566B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA200205566A 1999-12-15 2002-07-11 Cyclic quaternary ammonium compounds. ZA200205566B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA2292351 1999-12-15

Publications (1)

Publication Number Publication Date
ZA200205566B true ZA200205566B (en) 2003-11-17

Family

ID=4164887

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200205566A ZA200205566B (en) 1999-12-15 2002-07-11 Cyclic quaternary ammonium compounds.

Country Status (19)

Country Link
US (1) US20030166629A1 (et)
EP (1) EP1278731A1 (et)
JP (1) JP2003516966A (et)
KR (1) KR20020074170A (et)
CN (1) CN1425005A (et)
AU (1) AU2334501A (et)
BG (1) BG106816A (et)
BR (1) BR0016431A (et)
CZ (1) CZ20022095A3 (et)
EE (1) EE200200314A (et)
HU (1) HUP0301686A2 (et)
IL (1) IL150179A0 (et)
IS (1) IS6417A (et)
MX (1) MXPA02006051A (et)
NO (1) NO20022870L (et)
PL (1) PL356032A1 (et)
WO (1) WO2001044192A1 (et)
YU (1) YU44102A (et)
ZA (1) ZA200205566B (et)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007322033B2 (en) 2006-11-20 2013-07-11 President And Fellows Of Harvard College Methods, compositions, and kits for treating pain and pruritis
CA2717042A1 (en) * 2008-03-11 2009-09-17 The General Hospital Corporation Methods, compositions, and kits for treating pain and pruritis
JP6205133B2 (ja) * 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
US10130632B2 (en) 2012-11-27 2018-11-20 Beth Israel Deaconess Medical Center, Inc. Methods for treating renal disease
WO2015120069A1 (en) 2014-02-04 2015-08-13 Beth Israel Deaconess Medical Center, Inc. Methods and kits for the diagnosis and treatment of pancreatic cancer
AU2016301282B2 (en) * 2015-08-03 2022-03-17 Children's Medical Center Corporation Charged ion channel blockers and methods for use
MA55307A (fr) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueurs de canaux ioniques chargés et procédés d'utilisation
KR102887727B1 (ko) 2019-03-11 2025-11-18 녹시온 테라퓨틱스 인코포레이티드 에스테르 치환된 이온 채널 차단제 및 사용 방법
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
JP7692834B2 (ja) 2019-03-11 2025-06-16 ノシオン セラピューティクス,インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
AU2020380118A1 (en) 2019-11-06 2022-05-19 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP4118070A4 (en) 2020-03-11 2024-04-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI58632C (fi) * 1978-02-07 1981-03-10 Orion Yhtymae Oy Foerfarande foer framstaellning av anilider med antitussiv verkan

Also Published As

Publication number Publication date
IL150179A0 (en) 2002-12-01
KR20020074170A (ko) 2002-09-28
AU2334501A (en) 2001-06-25
PL356032A1 (en) 2004-06-14
WO2001044192A1 (en) 2001-06-21
BR0016431A (pt) 2002-10-01
CZ20022095A3 (cs) 2003-02-12
EE200200314A (et) 2003-08-15
NO20022870L (no) 2002-08-14
MXPA02006051A (es) 2004-08-23
US20030166629A1 (en) 2003-09-04
EP1278731A1 (en) 2003-01-29
BG106816A (en) 2003-04-30
IS6417A (is) 2002-06-12
CN1425005A (zh) 2003-06-18
JP2003516966A (ja) 2003-05-20
NO20022870D0 (no) 2002-06-14
HUP0301686A2 (hu) 2003-08-28
YU44102A (sh) 2005-09-19

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