YU47044B - PROCEDURE FOR OBTAINING HIGH-MOLECULAR HYDROXYPROPYL-METHYLCELLULOSE PROLONGED TABLETS - Google Patents
PROCEDURE FOR OBTAINING HIGH-MOLECULAR HYDROXYPROPYL-METHYLCELLULOSE PROLONGED TABLETSInfo
- Publication number
- YU47044B YU47044B YU40687A YU40687A YU47044B YU 47044 B YU47044 B YU 47044B YU 40687 A YU40687 A YU 40687A YU 40687 A YU40687 A YU 40687A YU 47044 B YU47044 B YU 47044B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- weight
- methylcellulose
- tablets
- prolonged
- procedure
- Prior art date
Links
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 title abstract 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 title abstract 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 title abstract 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 title abstract 2
- 230000002035 prolonged effect Effects 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- -1 hydroxypropoxyl Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
POSTUPAK ZA DOBIJANJE TABLETA SA PRODUŽENIM DELOVANJEM NA BAZI HIDROKSIPROPIL-METILCELULOZE VELIKE MOLEKULARNE MASE, koje sadrže terapeutski aktivnu lekovitu komponentu i nosač, naznačen time, što se presuje i oblikuje smeša terapeutski aktivne lekovite omponente i nosača koji se sastoji od hidroksipropilmetil-celuloze, sa sadržajem metoksila od 28 do 309 mas.%, hidroksipropoksila od 7,5 do 12 mas.% i prosečnom molskom masom od najmanje 50.000, u količini od oko 20 do oko 40 mas.% tablete, u datom slučaju 10 mas% glicerol ditripalmitostearata i od oko 10 do oko 20 mas% mikrokristalne celuloze i drugih uobičajenih farmaceutski prihvatljivih pomoćnih materija.- Prijava sadrži još 1 zavisan zahtev.PROCESS FOR PREPARING LONG-MOLECULAR HYDROXYPROPYL-METHYLCELLULOSE PROBLEMS WITH EXTENDED ACTION, comprising a therapeutically active drug component containing methoxyl from 28 to 309% by weight, hydroxypropoxyl from 7.5 to 12% by weight and an average molecular weight of at least 50,000, in an amount of from about 20 to about 40% by weight of the tablet, optionally 10% by weight of glycerol ditripalmitostearate and from about 10 to about 20% by weight of microcrystalline cellulose and other customary pharmaceutically acceptable excipients.- The application contains 1 further dependent claim.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI8710406A SI8710406B (en) | 1987-03-11 | 1987-03-11 | Sustained release tablets on the basis of high molecular weight hydroxypropylmethylcellulose and a process for their manufacture |
| YU40687A YU47044B (en) | 1987-03-11 | 1987-03-11 | PROCEDURE FOR OBTAINING HIGH-MOLECULAR HYDROXYPROPYL-METHYLCELLULOSE PROLONGED TABLETS |
| EP19880103715 EP0284849B1 (en) | 1987-03-11 | 1988-03-09 | Sustained release tablets on the basis of high molecular weight hydroxypropylmethylcellulose and a process for their manufacture |
| DE19883882765 DE3882765T2 (en) | 1987-03-11 | 1988-03-09 | Delayed release tablets based on high molecular weight hydroxypropylmethyl cellulose and process for their preparation. |
| JP63056487A JPH0757726B2 (en) | 1987-03-11 | 1988-03-11 | Sustained release tablets based on high molecular weight hydroxypropyl methylcellulose |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU40687A YU47044B (en) | 1987-03-11 | 1987-03-11 | PROCEDURE FOR OBTAINING HIGH-MOLECULAR HYDROXYPROPYL-METHYLCELLULOSE PROLONGED TABLETS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU40687A YU40687A (en) | 1991-02-28 |
| YU47044B true YU47044B (en) | 1994-12-28 |
Family
ID=25549781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU40687A YU47044B (en) | 1987-03-11 | 1987-03-11 | PROCEDURE FOR OBTAINING HIGH-MOLECULAR HYDROXYPROPYL-METHYLCELLULOSE PROLONGED TABLETS |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0284849B1 (en) |
| JP (1) | JPH0757726B2 (en) |
| DE (1) | DE3882765T2 (en) |
| SI (1) | SI8710406B (en) |
| YU (1) | YU47044B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948437A (en) * | 1996-05-23 | 1999-09-07 | Zeneca Limited | Pharmaceutical compositions using thiazepine |
| ID20270A (en) * | 1997-05-18 | 1998-11-19 | Adel Abdel Wadood Gomaa Prof D | NEW TOPIC PREPARATES FOR TREATMENT OF THE PENIS-FUNCTION |
| US5895663A (en) * | 1997-07-31 | 1999-04-20 | L. Perrigo Company | Pseudoephedrine hydrochloride extended-release tablets |
| US5851555A (en) * | 1997-08-15 | 1998-12-22 | Fuisz Technologies Ltd. | Controlled release dosage forms containing water soluble drugs |
| US7771746B2 (en) | 1999-12-03 | 2010-08-10 | Polichem Sa | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
| HK1048254B (en) * | 1999-12-03 | 2005-06-03 | Polichem S.A. | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
| WO2003103634A1 (en) * | 2002-06-07 | 2003-12-18 | Ranbaxy Laboratories Limited | Sustained release oral dosage forms of gabapentin |
| EP1537880A4 (en) * | 2002-09-11 | 2009-07-01 | Takeda Pharmaceutical | PREPARATION FOR PROLONGED RELEASE |
| US20040109889A1 (en) | 2002-12-04 | 2004-06-10 | Bunick Frank J. | Surface treatment composition for soft substrates |
| AU2005265031A1 (en) * | 2004-06-17 | 2006-01-26 | Forest Laboratories, Inc. | Modified release formulation of memantine |
| EP2070520A1 (en) * | 2007-12-11 | 2009-06-17 | LEK Pharmaceuticals D.D. | Pharmaceutical composition comprising at least one active agent and a binder, which swells in an acidic media |
| US8912192B2 (en) | 2010-02-12 | 2014-12-16 | Taisho Pharmaceutical Co., Ltd | Extended release preparation |
| CN108721238A (en) * | 2017-04-17 | 2018-11-02 | 上海葆隆生物科技有限公司 | A lithium carbonate sustained-release tablet |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
| WO1985004100A1 (en) * | 1984-03-21 | 1985-09-26 | American Home Products Corporation | Sustained release pharmaceutical capsules |
| HU195729B (en) * | 1985-02-05 | 1988-07-28 | Sandoz Ag | Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides |
| GB2181053B (en) * | 1985-10-01 | 1990-05-23 | Sandoz Ltd | Pharmaceutical formulations with controlled release of the active substance |
| US4734285A (en) * | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
-
1987
- 1987-03-11 YU YU40687A patent/YU47044B/en unknown
- 1987-03-11 SI SI8710406A patent/SI8710406B/en not_active IP Right Cessation
-
1988
- 1988-03-09 DE DE19883882765 patent/DE3882765T2/en not_active Expired - Fee Related
- 1988-03-09 EP EP19880103715 patent/EP0284849B1/en not_active Expired - Lifetime
- 1988-03-11 JP JP63056487A patent/JPH0757726B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| YU40687A (en) | 1991-02-28 |
| JPH0757726B2 (en) | 1995-06-21 |
| EP0284849B1 (en) | 1993-08-04 |
| EP0284849A1 (en) | 1988-10-05 |
| JPS63290818A (en) | 1988-11-28 |
| DE3882765D1 (en) | 1993-09-09 |
| DE3882765T2 (en) | 1994-03-10 |
| SI8710406A (en) | 1996-08-31 |
| SI8710406B (en) | 1998-08-31 |
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