YU28404A - Flashmelt oral dosage formulation - Google Patents
Flashmelt oral dosage formulationInfo
- Publication number
- YU28404A YU28404A YU28404A YUP28404A YU28404A YU 28404 A YU28404 A YU 28404A YU 28404 A YU28404 A YU 28404A YU P28404 A YUP28404 A YU P28404A YU 28404 A YU28404 A YU 28404A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- granules
- sodium
- oral dosage
- dosage forms
- prepared
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000008187 granular material Substances 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229920002785 Croscarmellose sodium Polymers 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 229920000881 Modified starch Polymers 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 229960001681 croscarmellose sodium Drugs 0.000 abstract 1
- 229960000913 crospovidone Drugs 0.000 abstract 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 abstract 1
- 235000013809 polyvinylpolypyrrolidone Nutrition 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 229940083542 sodium Drugs 0.000 abstract 1
- 235000015424 sodium Nutrition 0.000 abstract 1
- 229920003109 sodium starch glycolate Polymers 0.000 abstract 1
- 229940079832 sodium starch glycolate Drugs 0.000 abstract 1
- 239000008109 sodium starch glycolate Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Seasonings (AREA)
Abstract
There is provided granules for the production of improved flash-melt pharmaceutical oral dosage forms. In addition to one or more medicaments, the granules are composed of an excipient combination consisting of a superdisintegrant (of two or more agents selected from the group consisting of crospovidone, croscarmellose sodium, sodium, sodium starch glycolate, low-substituted hydroxypropyl cellulose or pregelatinized starch), a dispersing agent, a distributing agent, and a binder and may also include other conventional ingredients such as sweetening and flavoring agents. The subject granules are advantageous in that they are stable and can be prepared without the aid of solvents and without the need for special environments or handling. Dosage forms, especially tablets, prepared thereform on conventional equipment disintegrate in the mouth in under about twenty five seconds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| YU28404 | 2001-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU28404A true YU28404A (en) | 2006-08-17 |
Family
ID=47750095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU28404A YU28404A (en) | 2001-10-09 | 2001-10-09 | Flashmelt oral dosage formulation |
Country Status (1)
| Country | Link |
|---|---|
| YU (1) | YU28404A (en) |
-
2001
- 2001-10-09 YU YU28404A patent/YU28404A/en unknown
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