YU2000A - Farmaceutski preparat koji sadrži atorvastatin i antihipertenzivni agens - Google Patents
Farmaceutski preparat koji sadrži atorvastatin i antihipertenzivni agensInfo
- Publication number
- YU2000A YU2000A YU2000A YU2000A YU2000A YU 2000 A YU2000 A YU 2000A YU 2000 A YU2000 A YU 2000A YU 2000 A YU2000 A YU 2000A YU 2000 A YU2000 A YU 2000A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- atorvastatin
- combinations
- combination therapy
- antihypertensive agent
- hyperlipidemia
- Prior art date
Links
- XUKUURHRXDUEBC-KAYWLYCHSA-N Atorvastatin Chemical compound C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-KAYWLYCHSA-N 0.000 title abstract 3
- XUKUURHRXDUEBC-UHFFFAOYSA-N Atorvastatin Natural products C=1C=CC=CC=1C1=C(C=2C=CC(F)=CC=2)N(CCC(O)CC(O)CC(O)=O)C(C(C)C)=C1C(=O)NC1=CC=CC=C1 XUKUURHRXDUEBC-UHFFFAOYSA-N 0.000 title abstract 3
- 229940030600 antihypertensive agent Drugs 0.000 title abstract 3
- 239000002220 antihypertensive agent Substances 0.000 title abstract 3
- 229960005370 atorvastatin Drugs 0.000 title abstract 3
- 238000002648 combination therapy Methods 0.000 title 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 2
- 230000000747 cardiac effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000024891 symptom Diseases 0.000 abstract 2
- 239000011885 synergistic combination Substances 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Pyrrole Compounds (AREA)
Abstract
Ovaj pronalazak se odnosi na farmaceutske kombinacije atorvastatina ili njegove farmaceutski prihvatljive soli i antihipertenzivnih agenasa. Ovaj pronalazak se, takodje, odnosi na aditive i sinergističke kombinacije atorvastatina ili njegove farmaceutski prihvatljive soli.[This invention relates to pharmaceutical combinations of atorvastatin or a pharmaceutically acceptable salt thereof and antihypertensive agents, kits containing such combinations and methods of using such combinations to treat subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and to treat subjects presenting with symptoms of cardiac risk, including humans. This invention also relates to additive and synergistic combinations of atorvastatin or a pharmaceutically acceptable salt thereof and antihypertensive agents whereby those synergistic combinations are useful in treating subjects suffering from angina pectoris, atherosclerosis, combined hypertension and hyperlipidemia and those subjects presenting with symptoms of cardiac risk, including humans.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5727697P | 1997-08-29 | 1997-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU2000A true YU2000A (sh) | 2002-12-10 |
Family
ID=22009602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU2000A YU2000A (sh) | 1997-08-29 | 1998-08-11 | Farmaceutski preparat koji sadrži atorvastatin i antihipertenzivni agens |
Country Status (41)
| Country | Link |
|---|---|
| US (2) | US20020099046A1 (sh) |
| EP (1) | EP1009400B1 (sh) |
| JP (2) | JP2001514223A (sh) |
| KR (3) | KR20010022477A (sh) |
| CN (3) | CN1473567A (sh) |
| AP (1) | AP1191A (sh) |
| AR (1) | AR016399A1 (sh) |
| AT (1) | ATE285767T1 (sh) |
| AU (1) | AU740424B2 (sh) |
| BG (1) | BG64724B1 (sh) |
| BR (1) | BR9811556A (sh) |
| CA (1) | CA2296723A1 (sh) |
| CO (1) | CO4970724A1 (sh) |
| DE (1) | DE69828413T2 (sh) |
| DZ (1) | DZ2595A1 (sh) |
| EA (1) | EA200000012A1 (sh) |
| EG (1) | EG24678A (sh) |
| ES (1) | ES2234134T3 (sh) |
| GT (1) | GT199800126A (sh) |
| HR (1) | HRP980474A2 (sh) |
| HU (1) | HUP0004318A3 (sh) |
| ID (1) | ID24118A (sh) |
| IL (2) | IL133962A0 (sh) |
| IS (1) | IS5341A (sh) |
| MA (1) | MA26536A1 (sh) |
| MY (1) | MY121008A (sh) |
| NO (1) | NO323987B1 (sh) |
| NZ (2) | NZ502280A (sh) |
| OA (1) | OA11291A (sh) |
| PA (1) | PA8457901A1 (sh) |
| PE (1) | PE107099A1 (sh) |
| PL (1) | PL339091A1 (sh) |
| PT (1) | PT1009400E (sh) |
| SA (1) | SA98190603B1 (sh) |
| SK (1) | SK1432000A3 (sh) |
| TN (1) | TNSN98155A1 (sh) |
| TR (1) | TR200000563T2 (sh) |
| UY (1) | UY25155A1 (sh) |
| WO (1) | WO1999011260A1 (sh) |
| YU (1) | YU2000A (sh) |
| ZA (1) | ZA987839B (sh) |
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| IL148127A0 (en) | 1999-08-30 | 2002-09-12 | Aventis Pharma Gmbh | Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events |
| AUPQ266199A0 (en) | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
| DE19944803A1 (de) * | 1999-09-20 | 2001-03-29 | Bayer Ag | Kombination von Dihydropyridinverbindungen und HMG-CoA-Reduktase-Inhibitoren und ihre Verwendung in Arzneimitteln |
| EP1218017B1 (en) | 1999-09-24 | 2005-11-16 | Vasogen Ireland Limited | Combination of a statin and ex-vivo treated blood for treating atherosclerosis |
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| US5447922A (en) * | 1994-08-24 | 1995-09-05 | Bristol-Myers Squibb Company | α-phosphonosulfinic squalene synthetase inhibitors |
| US5798375A (en) * | 1995-07-03 | 1998-08-25 | Sankyo Company, Limited | Treatment of arteriosclerosis and xanthoma |
| EA000514B1 (ru) * | 1995-11-02 | 1999-10-28 | Варнер-Ламберт Компани | Способ нормализации липопротеидного профиля плазмы крови у млекопитающего и фармацевтическая композиция для его осуществления |
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1998
- 1998-08-07 GT GT199800126A patent/GT199800126A/es unknown
- 1998-08-11 EP EP98935250A patent/EP1009400B1/en not_active Expired - Lifetime
- 1998-08-11 EA EA200000012A patent/EA200000012A1/ru unknown
- 1998-08-11 NZ NZ502280A patent/NZ502280A/xx unknown
- 1998-08-11 DE DE69828413T patent/DE69828413T2/de not_active Expired - Fee Related
- 1998-08-11 KR KR1020007001062A patent/KR20010022477A/ko not_active Ceased
- 1998-08-11 ID IDW20000196A patent/ID24118A/id unknown
- 1998-08-11 BR BR9811556-1A patent/BR9811556A/pt not_active Application Discontinuation
- 1998-08-11 CN CNA031430937A patent/CN1473567A/zh active Pending
- 1998-08-11 IL IL13396298A patent/IL133962A0/xx not_active IP Right Cessation
- 1998-08-11 WO PCT/IB1998/001230 patent/WO1999011260A1/en not_active Ceased
- 1998-08-11 PL PL98339091A patent/PL339091A1/xx unknown
- 1998-08-11 AT AT98935250T patent/ATE285767T1/de not_active IP Right Cessation
- 1998-08-11 AU AU84589/98A patent/AU740424B2/en not_active Ceased
- 1998-08-11 NZ NZ530630A patent/NZ530630A/en unknown
- 1998-08-11 CA CA002296723A patent/CA2296723A1/en not_active Abandoned
- 1998-08-11 CN CN98808463A patent/CN1268053A/zh active Pending
- 1998-08-11 JP JP2000508363A patent/JP2001514223A/ja not_active Withdrawn
- 1998-08-11 SK SK143-2000A patent/SK1432000A3/sk unknown
- 1998-08-11 ES ES98935250T patent/ES2234134T3/es not_active Expired - Lifetime
- 1998-08-11 KR KR10-2004-7019432A patent/KR20040106591A/ko not_active Ceased
- 1998-08-11 CN CNA031430929A patent/CN1473566A/zh active Pending
- 1998-08-11 KR KR10-2003-7000672A patent/KR20030015394A/ko not_active Ceased
- 1998-08-11 PT PT98935250T patent/PT1009400E/pt unknown
- 1998-08-11 YU YU2000A patent/YU2000A/sh unknown
- 1998-08-11 HU HU0004318A patent/HUP0004318A3/hu unknown
- 1998-08-11 TR TR2000/00563T patent/TR200000563T2/xx unknown
- 1998-08-17 PA PA19988457901A patent/PA8457901A1/es unknown
- 1998-08-24 PE PE1998000769A patent/PE107099A1/es not_active Application Discontinuation
- 1998-08-26 TN TNTNSN98155A patent/TNSN98155A1/fr unknown
- 1998-08-26 DZ DZ980205A patent/DZ2595A1/xx active
- 1998-08-26 UY UY25155A patent/UY25155A1/es not_active Application Discontinuation
- 1998-08-26 MA MA25228A patent/MA26536A1/fr unknown
- 1998-08-27 MY MYPI98003941A patent/MY121008A/en unknown
- 1998-08-27 EG EG102598A patent/EG24678A/xx active
- 1998-08-27 CO CO98049139A patent/CO4970724A1/es unknown
- 1998-08-27 AP APAP/P/1998/001332A patent/AP1191A/en active
- 1998-08-27 AR ARP980104287A patent/AR016399A1/es unknown
- 1998-08-28 ZA ZA9807839A patent/ZA987839B/xx unknown
- 1998-08-28 HR HR60/057,276A patent/HRP980474A2/hr not_active Application Discontinuation
- 1998-09-30 SA SA98190603A patent/SA98190603B1/ar unknown
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2000
- 2000-01-09 IL IL133962A patent/IL133962A/en unknown
- 2000-01-13 BG BG104075A patent/BG64724B1/bg unknown
- 2000-01-14 IS IS5341A patent/IS5341A/is unknown
- 2000-02-18 OA OA1200000040A patent/OA11291A/en unknown
- 2000-02-28 NO NO20000996A patent/NO323987B1/no unknown
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2001
- 2001-10-23 US US10/045,329 patent/US20020099046A1/en not_active Abandoned
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2003
- 2003-05-19 US US10/442,285 patent/US20030199492A1/en not_active Abandoned
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2004
- 2004-07-22 JP JP2004214382A patent/JP2005041875A/ja not_active Withdrawn
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