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WO2026008758A1 - Pointe de pipetage, agencement de pointe, système de manipulation de liquide et procédé d'éclairage d'un échantillon biologique - Google Patents

Pointe de pipetage, agencement de pointe, système de manipulation de liquide et procédé d'éclairage d'un échantillon biologique

Info

Publication number
WO2026008758A1
WO2026008758A1 PCT/EP2025/068933 EP2025068933W WO2026008758A1 WO 2026008758 A1 WO2026008758 A1 WO 2026008758A1 EP 2025068933 W EP2025068933 W EP 2025068933W WO 2026008758 A1 WO2026008758 A1 WO 2026008758A1
Authority
WO
WIPO (PCT)
Prior art keywords
tip
pipetting tip
pipetting
light
illumination light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2025/068933
Other languages
English (en)
Inventor
Jan ROHRER
Lucie JANDET
Jonas Goldowsky
Elise AEBY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Hoffmann La Roche Inc
Original Assignee
F Hoffmann La Roche AG
Hoffmann La Roche Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG, Hoffmann La Roche Inc filed Critical F Hoffmann La Roche AG
Publication of WO2026008758A1 publication Critical patent/WO2026008758A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0654Lenses; Optical fibres
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • B01L2300/168Specific optical properties, e.g. reflective coatings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Une pointe de pipetage (5) selon l'invention comprend au moins une paroi latérale (7), une extrémité distale (8) et une extrémité proximale (10), la pointe de pipetage (5) étant conçue pour servir de guide de lumière, une lumière d'éclairage (9) émise à partir d'une source de lumière (6) étant couplée dans la pointe de pipetage (5) et étant transmise à l'intérieur de ladite paroi latérale (7), de préférence par réflexion interne, et la lumière d'éclairage (9) s'échappant de la pointe de pipetage (5) au niveau de l'extrémité distale (8). En outre, l'invention concerne un agencement de pointe (2), un système de manipulation de liquide (1) et un procédé d'éclairage d'un échantillon biologique (16).
PCT/EP2025/068933 2024-07-05 2025-07-03 Pointe de pipetage, agencement de pointe, système de manipulation de liquide et procédé d'éclairage d'un échantillon biologique Pending WO2026008758A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP24186697.9 2024-07-05
EP24186697 2024-07-05

Publications (1)

Publication Number Publication Date
WO2026008758A1 true WO2026008758A1 (fr) 2026-01-08

Family

ID=91853476

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2025/068933 Pending WO2026008758A1 (fr) 2024-07-05 2025-07-03 Pointe de pipetage, agencement de pointe, système de manipulation de liquide et procédé d'éclairage d'un échantillon biologique

Country Status (1)

Country Link
WO (1) WO2026008758A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130171673A1 (en) * 2010-06-30 2013-07-04 Csem Centre Suisse D'electronique Et De Micro- Technique Sa Recherche Et Develo Pipette tip, pipette system and method for performing analysis with the pipette tip and system
US20160124009A1 (en) * 2011-09-25 2016-05-05 Theranos, Inc. Systems and methods for fluid and component handling
WO2016156051A1 (fr) 2015-03-27 2016-10-06 Brian Page Pipette comprenant une source de lumière et un détecteur
EP3567359A1 (fr) * 2018-05-08 2019-11-13 Sartorius Biohit Liquid Handling Oy Système de manipulation de liquides et procédé permettant d'analyser l'état d'une pointe

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130171673A1 (en) * 2010-06-30 2013-07-04 Csem Centre Suisse D'electronique Et De Micro- Technique Sa Recherche Et Develo Pipette tip, pipette system and method for performing analysis with the pipette tip and system
US20160124009A1 (en) * 2011-09-25 2016-05-05 Theranos, Inc. Systems and methods for fluid and component handling
WO2016156051A1 (fr) 2015-03-27 2016-10-06 Brian Page Pipette comprenant une source de lumière et un détecteur
EP3567359A1 (fr) * 2018-05-08 2019-11-13 Sartorius Biohit Liquid Handling Oy Système de manipulation de liquides et procédé permettant d'analyser l'état d'une pointe

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