WO2024098093A1

WO2024098093A1 - Skincare treatment composition for the relief of the symptoms of acne and rosacea

Info

Publication number: WO2024098093A1
Application number: PCT/AU2023/051102
Authority: WO
Inventors: Elissa O'KEEFE
Original assignee: More Happy Days Pty Ltd
Current assignee: More Happy Days Pty Ltd
Priority date: 2022-11-08
Filing date: 2023-11-01
Publication date: 2024-05-16
Anticipated expiration: 2025-05-08

Abstract

A composition for the treatment of acne and rosacea that comprises Caprylic/Capric Triglyceride, Glycerin, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Cetearyl Alcohol, Prunus Amygdalus (Sweet Almond) Dulcis Oil, Olea Europaea (Olive) Fruit Oil, Salicylic Acid, Glyceryl Stearate, Zea Mays (Com) Oil, Stearic Acid, Decyl Glucoside, Polysorbate 60, Malic Acid, Phenoxyethanol, Xanthan Gum, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Retinyl Palmitate, Simmondsia Chinensis (Jojoba) Seed Oil, Oenothera Biennis (Evening Primrose) Oil, Rosa Canina Fruit Oil, Hydroxyacetophenone, Lecithin, Ethylhexylglycerin, Citrus Paradisi (Grapefruit) Fruit Extract, Daucus Carota Sativa (Carrot) Root Extract, Chamomilla Recutita (Matricaria) Flower Extract, Althaea Officinalis (Marshmallow) Root Extract, Alfalfa Grass, Allantoin, Potassium Sorbate, Aloe Barbadensis Leaf Juice, Pullulan, Sclerotium Gum, Camellia Sinensis (Green Tea) Leaf Extract, Pyms Malus (Apple) Fruit Extract, Disodium EDTA, Beta Glucan, Lactic Acid, Propylene Glycol, Sodium Hydroxide, Alcohol, Honey Extract, Portulaca Oleracea Extract, Ascophyllum Nodosum Powder, Sodium Benzoate and water.

Description

Skincare treatment composition for the relief of the symptoms of acne and rosacea

Field of the invention

This invention is directed towards a novel chemical composition and is particularly directed to a chemical composition comprising natural products including tea tree oil which can be used as a treatment for acne and rosacea.

Background

It is estimated that acne vulgaris (acne) affects 645 million people worldwide while rosacea affects approximately 415 million. Common skin issues such as acne and rosacea are known to have similar impacts on the quality of life of patients as other chronic health issues such as back pain and diabetes.

Both diseases represent a significant economic and health burden regardless of where people with these conditions live. These skin conditions can affect work, school, mental health, and relationships. Acne fulminans can be life threatening and there are well established links between chronic skin conditions and anxiety, depression and at the most extreme, suicide.

It has been found that the improvement of acne and rosacea following successful treatment significantly improves quality of life indicators.

Prior art

The usual approach to acne and rosacea is the prescription of oral antibiotics. Acne is also widely controlled with topical benzoyl peroxide preparations.

Antibiotics provide suppression of the Cutibacterium acnes organism implicated in mild, moderate and severe acne and is prescribed for its anti-inflammatory actions for rosacea. It is not exactly known why antibiotics exert an anti-inflammatory response in the treatment of rosacea.

Antibiotic treatments are contributing to microbial resistance with evidence for this for both acne and rosacea. Microbial resistance has been described by the Australian Commission on Safety and Quality in Health Care as an ongoing public health and safety threat. Benzoyl peroxide is generally used for acne in a variety of strengths in multiple topical preparations for its antibacterial effects.

Benzoyl peroxide may impair the skin barrier and is also contraindicated for use in conjunction with common topical retinoid medications. Benzoyl peroxide is also well known for bleaching hair, clothes and bedlinen.

It is also known to use tea tree oil in treatment of acne. However, none of the prior art compositions containing tea tree oil are fully effective in treatment of acne and rosacea.

Notwithstanding that prior art compositions have an array of therapeutic uses, one disadvantage with those compositions is that they are not particularly effective against acne and rosacea.

It is an object of the present invention to overcome or ameliorate some of the disadvantages of the prior art. Accordingly, the present invention provides a useful alternative product and a novel method for the making the product and treatment of acne and rosacea.

Summary of the invention

The present invention provides a novel chemical composition containing a unique blend of botanical ingredients with proven results in the relief of acne symptoms and relieving the skin redness associated with rosacea.

The key components of the present invention are the active botanical ingredients including Melaleuca altemifolia (tea tree) oil for its antimicrobial and anti-inflammatory actions. It also contains other botanicals for the reduction of inflammation including Aloe barbadensis (aloe vera), Althaea officinalis (marshmallow), and Chamomilla matricaria (chamomile), Portulaca oleracea (purslane).

The novel composition of the present invention is packaged in an airless pump to maintain the stability of the active ingredients. The pump also delivers a measured dosage of 0.25mL of the product.

Detailed description of the invention

According to a first aspect of the invention, there is provided a composition for the treatment of acne which comprises Caprylic/Capric Triglyceride, Glycerin, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Cetearyl Alcohol, Prunus Amygdalus (Sweet Almond) Dulcis Oil, Olea Europaea (Olive) Fruit Oil, Salicylic Acid, Glyceryl Stearate, Zea Mays (Corn) Oil, Stearic Acid, Decyl Glucoside, Polysorbate 60, Malic Acid, Phenoxyethanol, Xanthan Gum, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Retinyl Palmitate, Simmondsia Chinensis (Jojoba) Seed Oil, Oenothera Biennis (Evening Primrose) Oil, Rosa Canina Fruit Oil, Hydroxyacetophenone, Lecithin, Ethylhexylglycerin, Citrus Paradisi (Grapefruit) Fruit Extract, Daucus Carota Sativa (Carrot) Root Extract, Chamomilla Recutita (Matricaria) Flower Extract, Althaea Officinalis (Marshmallow) Root Extract, Alfalfa Grass, Allantoin, Potassium Sorbate, Aloe Barbadensis Leaf Juice, Pullulan, Sclerotium Gum, Camellia Sinensis (Green Tea) Leaf Extract, Pyrus Malus (Apple) Fruit Extract, Disodium EDTA, Beta Glucan, Lactic Acid, Propylene Glycol, Sodium Hydroxide, Alcohol, Honey Extract, Portulaca Oleracea Extract, Ascophyllum Nodosum Powder, Sodium Benzoate and water.

In a preferred embodiment of the invention, by way of an example only, the novel composition based on w/w percentage is shown in the Table 1. It should be noted that the novel composition contains eight separate phases A, B, C, D, E, F, G and H as shown in the Table 1.

TABLE 1

In a further preferred embodiment, the present invention provides a process of making the novel composition comprising the following steps.

• Transfer phase A into a batch vessel, begin mixing on a moderate speed and heat to a temperature range of 70-75 Celsius.

• Add phase B into the batch vessel, mix until a uniform gel is formed.

• Add phase C into the batch vessel, mix until dissolved.

• Premix phase E, heat to 70-75 degrees Celsius and mix until all waxes and crystalline ingredients have dissolved.

• Transfer Phase E into the batch vessel, mix until uniform.

• Homogenise batch on high speed for a time appropriate to the batch size and flow rate of the homogeniser to achieve a uniform particle size.

• Cool batch to 50 degrees Celsius with continuous homogenisation.

• Add phase F into batch vessel, homogenise until uniform.

• Cool batch to 20-30 Degrees Celsius with continuous homogenisation.

• Cease homogenisation and add phase G into the batch vessel and mix until uniform.

Surprisingly, the novel composition of the present invention has demonstrated activity against acne and rosacea conditions, without requiring excessively large quantities of each ingredient. Therefore, while not wishing to be bound by any theory, there appears to be a surprisingly an unexpected advantage in having the combination of ingredients and the combination of ingredients in a particular concentration.

While, the individual components of the present invention may have been used in the treatment of acne and rosacea, the blend of oils and other components of the present invention in the set constituent concentration provide a synergistic result not obtained by applying any one component of the novel composition described in the present invention. The composition provided in the present invention is far superior to any of the compositions disclosed in the prior art. The novel composition of the present invention provides a reliable treatment for acne and rosacea relieving symptoms. The composition of the present invention can be used for the treatment of both acne and rosacea. In a further preferred embodiment, the present invention is a component of two separate treatment systems for acne and rosacea. The novel composition of the present invention can be used as a lotion, gel, serum, cream, balm or in any other suitable form.

The treatment system for acne includes the present invention, a detoxifying cleanser, a repair and rebalancing lotion, and a restoring moisturiser.

The treatment system for rosacea includes the present invention, a soothing cleanser, a balancing serum, and a nurture and repairing lotion.

The novel method for treating acne comprises the steps of cleansing the affected area using a detox cleanser, applying 0.25 ml the novel exfoliant composition of the present invention, applying a repairing and rebalancing mask and finally applying a restoring moisturiser.

The novel method for treating rosacea comprises the steps of cleansing the affected area using a soothing cleanser, applying a balancing treatment serum, applying 0.25 ml of the novel exfoliant composition of the present invention, and finally applying a nurturing and repairing moisturiser.

It should be noted that while the invention has described what are believed to be the preferred embodiments of the invention, those skilled in the art will recognise that other and further modifications may be made thereto without departing from the spirit of the invention, and it is intended to claim all such changes and modifications as fall within the scope of the invention. Although the invention has been described with reference to specific examples, it will be appreciated by those skilled in the art that the invention may be embodied in many other forms.

Claims

The claims defining the invention are as follows:

1. A composition for the treatment of acne and rosacea that comprises Caprylic/Capric Triglyceride, Glycerin, Melaleuca Altemifolia (Tea Tree) Leaf Oil, Cetearyl Alcohol, Prunus Amygdalus (Sweet Almond) Dulcis Oil, Olea Europaea (Olive) Fruit Oil, Salicylic Acid, Glyceryl Stearate, Zea Mays (Corn) Oil, Stearic Acid, Decyl Glucoside, Polysorbate 60, Malic Acid, Phenoxyethanol, Xanthan Gum, Helianthus Annuus (Sunflower) Seed Oil, Tocopherol, Retinyl Palmitate, Simmondsia Chinensis (Jojoba) Seed Oil, Oenothera Biennis (Evening Primrose) Oil, Rosa Canina Fruit Oil, Hydroxyacetophenone, Lecithin, Ethylhexylglycerin, Citrus Paradisi (Grapefruit) Fruit Extract, Daucus Carota Sativa (Carrot) Root Extract, Chamomilla Recutita (Matricaria) Flower Extract, Althaea Officinalis (Marshmallow) Root Extract, Alfalfa Grass, Allantoin, Potassium Sorbate, Aloe Barbadensis Leaf Juice, Pullulan, Sclerotium Gum, Camellia Sinensis (Green Tea) Leaf Extract, Pyrus Malus (Apple) Fruit Extract, Disodium EDTA, Beta Glucan, Lactic Acid, Propylene Glycol, Sodium Hydroxide, Alcohol, Honey Extract, Portulaca Oleracea Extract, Ascophyllum Nodosum Powder, Sodium Benzoate and water.

2. A composition for treatment of acne and rosacea that comprises eight separate phases A, B, C, D, E , F, G and H wherein the phase A comprises water 58%w/w; phase B comprises Beta Glucan 0.05% w/w and a gelling agent consisting of Xanthan Gum, Lecithin, Sclerotium Gum and Pullulan 1% w/w; phase C comprises Glycerin 5% w/w, Aloe Barbadensis Leaf Juice0.1% w/w, Hydroxyacetophenone 0.5% w/w, Potassium Sorbate 0.1% w/w, Phenoxyethanol Ethylhexylglycerin 1% w/w, Allantoin 0.1% w/w, Disodium EDTA 0.05% w/w, Organic Manuka Honey 0.1% w/w and Malic Acid 1% w/w; phase D comprising Polysorbate 60 1% w/w and Decyl Glucoside 2% w/w; phase E comprising Caprylic/Capric Triglyceride 10% w/w, Glyceryl Stearate 2% w/w, Cetearyl Alcohol 3 %w/w, Stearic Acid i% w/w, Salicylic Acid 2 % w/w, Olea Europaea (Olive) Fruit Oil 2% w/w, Prunus Amygdalus (Sweet Almond) Dulcis Oil 2% w/w, Rosa Canina Fruit Oil 0.5% w/w, Oenothera Biennis (Evening Primrose) Oil 0.5% w/w, Simmondsia Chinensis (Jojoba) Seed Oil 0.5% w/w, Retinyl Palmitate 0.5% w/w, Zea Mays (Corn) Oil 1% w/w, Tocopherol Helianthus Annuus (Sunflower) Seed Oil 1% w/w and Chlorophyl Oil (Alfalfa Grass) 0.1 % w/wg phase F comprising Melaleuca Alternifolia (Tea Tree) Leaf Oil 3% w/w; phase G comprising Pyrus Malus (Apple) Fruit Extract Sodium Benzoate 0.1% w/w, Althaea Officinalis (Marshmallow) Root Extract 0.1% w/w, Chamomilla Recutita (Matricaria) Flower Extract 0.1% w/w, Camellia Sinensis (Green Tea) Leaf Extract Sodium Benzoate 0.1% w/w, Daucus Carota Saliva (Carrot) Root Extract Sodium Benzoate 0.1% w/w, Citrus Paradisi (Grapefruit) Fruit Extract Sodium Benzoate 0.1% w/w, Seaweed liquid extract 0.1% w/w and Glycerine Water Portulaca Oleracea Extract 0.1% w/w; and phase H comprising Lactic Acid water 0.05% w/w and Sodium Hydroxide solution (20% strength) 0.05% w/w.

3. A composition as defined in claim 1 or 2 in the form of a lotion, gel, serum, cream, balm or in any other suitable form for the treatment of acne and rosacea.

4. A method for making a compsoition as defined in claim 2 which comprises the steps of

• Transferring phase A into a batch vessel, mixing on a moderate speed and heat to a temperature range of 70-75 Celsius;

• Adding phase B into the batch vessel, mixing until a unifirm gel is formed;

• Adding phase C into the batch vessel, mixing until dissolved;

• Premixing phase E, heating to 70-75 degrees Celsius and mixing until all waxes and crystalline ingredients have dissolved;

• Tranferring Phase E into the batch vessel, mixing until uniform;

• Homogenising the batch on high speed for a time appropriate to the batch size and flow rate of the homogeniser to achieve a uniform particle size;

• Cooling batch to 50 degrees Celsius with continuous homogenisation;

• Adding phase F into batch vessel and homogenising until uniform;

• Cooling batch to 20-30 Degrees Celsius with continuous homogenisation; and

• Ceasing of homogenisation and adding phase G into the batch vessel and mixing until uniform.

5. The composition as defined in claims 1 or 2 wherin it is packaged in an airless pump to maintain the stability of the active ingredients and delivering a measured dosage of 0.25mL of the product.

6. A kit for treatment of acne comprising a detox cleanser, the composition as defined in claim 1 or 2 packaged in an airless pump to maintain the stability of the active ingredients and delivering a measured dosage of 0.25ml, a repair and rebalancing mask and a restoring moisturiser. A kit for treatment of rosacea comprising a soothing cleanser, a balancing treatment serum, the composition as defined in claim 1 or 2 packaged in an airless pump to maintain the stability of the active ingredients and delivering a measured dosage of 0.25ml and a nurturing and repairing moisturiser. The method for treating acne comprising the steps of cleansing the affected area using a detox cleanser, applying 0.25 ml of the composition as defined in claims 1 or 2, applying a repairing and rebalancing mask and finally applying a restoring moisturiser. The method for treating rosacea comprising the steps of cleansing the affected area using a soothing cleanser, applying a balancing treatment serum, applying 0.25 ml of the composition as defined in claims 1 or 2 and finally applying a nurturing and repairing moisturiser.