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WO2019162720A1 - Dispositif pour le traitement de l'obésité - Google Patents

Dispositif pour le traitement de l'obésité Download PDF

Info

Publication number
WO2019162720A1
WO2019162720A1 PCT/IB2018/051071 IB2018051071W WO2019162720A1 WO 2019162720 A1 WO2019162720 A1 WO 2019162720A1 IB 2018051071 W IB2018051071 W IB 2018051071W WO 2019162720 A1 WO2019162720 A1 WO 2019162720A1
Authority
WO
WIPO (PCT)
Prior art keywords
volume
stomach cavity
stomach
actuator
encapsulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2018/051071
Other languages
English (en)
Spanish (es)
Inventor
Samuel ESCOBAR GONZÁLEZ
Simón VILLA ARANGO
Javier Enrique CAMACHO COGOLLO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad EIA
Original Assignee
Universidad EIA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad EIA filed Critical Universidad EIA
Priority to PCT/IB2018/051071 priority Critical patent/WO2019162720A1/fr
Publication of WO2019162720A1 publication Critical patent/WO2019162720A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents

Definitions

  • the present invention is encompassed in the gastroenterological field of medicine, and more specifically in the systems used for weight loss.
  • Invasive devices currently used in weight loss treatments such as the balloon or gastric band, reduce the effective volume of the stomach cavity, thus creating a feeling of fullness or fullness to patients with a smaller amount of food, leading to These people eat less food and therefore a loss of weight is induced in these.
  • the devices currently used are admitted to patients either orally in the case of the gastric balloon, or by minimally invasive surgery when talking about the gastric band. Patients who undergo this treatment have a high probability of suffering constant episodes of vomiting, dyspepsia and / or reflux, among others, when eating food, due to the effect created by the elements mentioned above. In other words, the reduction in gastric volume available through these devices makes gastric filling easier, causing the aforementioned adverse effects and food rejection.
  • gastric balls or bands currently implemented that allow to change their internal volume implicitly require that this be changed in an invasive manner, as for example in the one disclosed in the patent document US20090149879-A1.
  • the volume and pressure they exert or exert on them is not fed back at any time to users or health care staff.
  • the present invention solves this problem, by presenting an electromechanical device that allows the modification of the volume available in the stomach cavity remotely without the need to intervene the patient for it.
  • the present invention consists of a device for the treatment of obesity.
  • the device is implanted inside the stomach cavity and can vary in a controlled way the volume it occupies inside the stomach, without the need for external intervention.
  • the device may have actuators or measuring elements, which can be used to perform different tasks within the patient's stomach.
  • Through a wireless communication the device of the present invention can communicate with an external device that allows the system to be checked, controlled or recalibrated without the need for invasive interventions to patients.
  • the device is designed to be displaced inside the stomach using magnetic fields generated from outside the patient. Additionally, a wireless charging system is implemented to replenish the battery or batteries that power the device.
  • the device for the treatment of obesity through its implantation in the stomach cavity of a patient, comprises the following elements:
  • a volume sensor that obtains information through optical, resistive, piezoelectric, piezoresistive or ultrasonic transducers, among others, configured to measure the volume of the expanded element.
  • the actuator configured to regulate said volume by controlling the volume of the expanded element.
  • the actuator is composed of an electromechanical element that allows the volume to be modified.
  • a control unit configured to receive said commands and proceed, depending on the information contained in said command and the information from the volume sensor, to control the volume of the expanded element by means of the actuator.
  • a source of energy storage for example one or more batteries, to power the electronic components of the device.
  • a wireless charging system that allows wireless charging of the energy storage source from outside the stomach cavity in a non-invasive manner.
  • the device may comprise a ferromagnetic element to allow the device to move from the outside of the stomach cavity in a non-invasive manner, for example by means of a magnet.
  • the device comprises light emitting means, implemented for example by one or more LEDs, to illuminate the stomach cavity, and one or several cameras housed in the encapsulation and configured to capture images of the stomach cavity.
  • the device can transmit these images abroad wirelessly, for review by a specialist.
  • the transmission of the images can be done either through a wireless module installed in the cameras themselves or using the device's wireless media.
  • the encapsulation may comprise a plurality of openings to house electronic or electromechanical elements of the device.
  • the device can comprise one or more sensors (acidity sensor, pressure sensor, etc.) housed in the openings for the measurement of one or several variables of interest inside the stomach cavity, such as the degree of heartburn
  • the device may comprise a medication dispenser configured to deposit drugs in a controlled manner inside the stomach cavity through one of the openings of the encapsulation.
  • the control unit may be configured to gradually increase the volume of the expanded element according to an established weight loss program.
  • the control unit may be configured, once the weight loss program is over, to gradually decrease the volume of the expanded element.
  • the main objective of the present invention is to provide a device that allows control over the available volume of the stomach cavity, an action performed remotely by wireless and non-invasive commands, allowing the patient a less aggressive treatment over the duration of this.
  • Another optional objective of the present invention is to make measurements, through different sensors housed in the device, of different variables (eg acidity, pressure, temperature, presence of substances of interest such as glucose or the concentration of a medicine, among others) within the stomach cavity to provide information of special interest to specialists about some of the events that occur inside the stomach and know the patient's condition.
  • variables eg acidity, pressure, temperature, presence of substances of interest such as glucose or the concentration of a medicine, among others
  • the device can incorporate the additional functionality of controlled dispensing of medications when the patient requires it, either when programmed temporarily or when any of the measured variables leave a set range.
  • the device can also be used to implement a method of weight loss associated with a feedback system, through a programmed control that gradually increases the volume it occupies inside the stomach until reaching a desired value, then adapting to the patient's response until At the end of the treatment, its impact begins to decrease (by reducing the volume) also in a controlled manner and without external supervision.
  • Figure 1 shows a front view of the device.
  • Figure 2 shows a bottom plan view of the device.
  • Figure 3 shows a right side view of the device.
  • Figure 4 shows a left side view of the device.
  • the present invention relates to a device for the treatment of obesity, which is implanted within the stomach cavity.
  • Figure 1 shows a front elevation view of the device 1 for treatment of obesity, which comprises an expandable element 2, which changes volume within the stomach by the action of an actuator 7 comprising an electromechanical element that allows the volume to be modified according to be programmed to perform its therapeutic action.
  • an actuator 7 comprising an electromechanical element that allows the volume to be modified according to be programmed to perform its therapeutic action.
  • this expandable element 2 increases or decreases the stomach's ability to house food and therefore contributes to weight loss.
  • the device 1 also comprises an encapsulation 3 where the electronic and electromechanical components of the device are housed.
  • the encapsulation It has openings (4a, 4b, 4c) that can be used to locate the different types of electronic, mechanical or electromechanical elements.
  • the end of the expanded element 2 is fixed to the encapsulation 3, so that the upper base of the encapsulation 3 and the peripheral wall of the expanded element 2 generate a volume 12, controllable by the device itself.
  • the expanded element 2 is manufactured in a preferred embodiment by a flexible and soft material, for example silicone, which allows the control of said volume 12 by changing the pressure of a fluid, for example air, inside.
  • the expanding element 2 may be made of a rigid material, whereby the change in volume does not depend on the pressure inside it, but on the displacement of its peripheral walls by means of the action of the actuator 7.
  • a wireless charger or wireless charging system 5 an element that allows wireless charging of an energy storage source (eg one or several rechargeable batteries) located inside the device (not shown in the figure).
  • an energy storage source eg one or several rechargeable batteries located inside the device (not shown in the figure).
  • the actuator 7 is implemented by pneumatic volume control means for injecting or dislodging a fluid, for example air, in volume 12, and the sensors 6 include a pressure sensor for measuring the pressure of the fluid housed in the inside of volume 12.
  • Figure 2 represents a bottom view of the device 1 where you can see additional access ports or openings (8a, 8b) and a ferromagnetic element 9 (eg a magnet) used for the movement or relocation of the device 1 from the outside of non-invasive way.
  • a ferromagnetic element 9 eg a magnet
  • Figures 3 and 4 illustrate, respectively, a right and left side view of the device 1, where a port or cavity can be seen on both sides of the encapsulation 3 of the device for locating in each of them a camera (10a, 10b) responsible for transmitting images of the inside of the stomach in case a timely review of the stomach cavity is needed.
  • Light emitting elements or means (1 1 a, 1 1 b) are placed around the chamber that allow the stomach cavity to be illuminated when examinations are to be performed.
  • a single camera is used, instead of two, to increase autonomy and reduce size, complexity and cost.
  • ferromagnetic element 9 located at the base of the device 1, in other possible embodiments more ferromagnetic elements can be incorporated in the contour of the package 3, for example on its sides, to allow more degrees of freedom and greater control of the rotation of the device 1, performed externally by means of one or more magnets. In this way, you can have greater control of the orientation of the device 1 and the rotation of the cameras (10a, 10b).
  • the device 1 After implantation in the stomach, the device 1 can change the volume it occupies remotely without having to intervene the patient.
  • the device 1 communicates wirelessly, using a wireless communications module (for example, using Bluetooth low energy), with a device external to the patient with which an exchange of data between the two parties can be made.
  • the control unit housed or supported in the package 3 can receive remote commands for the control of the volume of the expandable element 2.
  • the control unit proceeds to regulate the volume 12 of the expandable element 2 , depending on the information contained in said command and the information coming from the sensors 6 by means of the actuator 7.
  • the control unit is constantly reading variables of interest within the stomach captured by the different sensors of device 1, which can be stored in an internal memory of the control unit or sent to the external unit for further analysis.
  • the control unit can be implemented, for example, by a microcontroller.
  • the actuator 7 of the device 1 comprises an electromechanical element that, by controlling the volume of the expandable element 2, allows it to change its shape to occupy more or less space within the stomach cavity.
  • the wireless charging system 5 allows to receive the necessary energy, transferred from an external system, to recharge an internal energy storage source (e.g. one) of the device.
  • the device 1 has on the periphery of its package 3 different access ports or openings (4a, 4b, 4c, 8a, 8b) where additional electronic or electromechanical elements, such as actuators or sensors, among others, can be located.
  • the ferromagnetic element 9 implemented for example by means of a magnet, allows the relocation or movement of device 1 into the stomach cavity. Said relocation is achieved by using an external electromagnetic field, which moves the device 1 in the desired direction.
  • the actuator 7 is an electromechanical element responsible for making the change in the volume occupied by the expandable element 2, thereby modifying the volume available in the stomach cavity.
  • the volume change can be done in different ways, such as pneumatically or hydraulically. Due to the location of the device 1 within the organism, all the materials used that may come into contact with the patient are biocompatible and implantable grade.

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

La présente invention concerne un dispositif pour le traitement de l'obésité par implantation dans la cavité stomacale, qui comprend un boîtier (3); un élément expansible (2) qui définit un volume (12) fermé, un capteur de pression (6), un actionneur (7) pour commander le volume (12) dans l'élément expansible (2), un module de communciation sans fil, une unité de commande qui reçoit sans fil des instructions à distance pour réaliser la commande du volume de l'élément expansible (2) au moyen de l'actionneur (7), une batterie et un système de charge sans fil (5) de la batterie. Le dispositif (1) peut contenir des caméras (10a, 10b) et des émetteurs de lumière (11a, 11b) pour capturer et transmettre sans fil des images de l'intérieur de la cavité stomacale. Le dispositif fournit au patient un traitement non invasif par la commande à distance du volume utile de la cavité stomacale.
PCT/IB2018/051071 2018-02-21 2018-02-21 Dispositif pour le traitement de l'obésité Ceased WO2019162720A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IB2018/051071 WO2019162720A1 (fr) 2018-02-21 2018-02-21 Dispositif pour le traitement de l'obésité

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2018/051071 WO2019162720A1 (fr) 2018-02-21 2018-02-21 Dispositif pour le traitement de l'obésité

Publications (1)

Publication Number Publication Date
WO2019162720A1 true WO2019162720A1 (fr) 2019-08-29

Family

ID=67687005

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2018/051071 Ceased WO2019162720A1 (fr) 2018-02-21 2018-02-21 Dispositif pour le traitement de l'obésité

Country Status (1)

Country Link
WO (1) WO2019162720A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080243071A1 (en) * 2007-03-30 2008-10-02 Quijano Rodolfo C Intragastric balloon system and therapeutic processes and products
WO2010045477A2 (fr) * 2008-10-16 2010-04-22 Obalon Therapeutics, Inc. Dispositif occupant un volume intra-gastrique et son procédé de fabrication
WO2011063307A1 (fr) * 2009-11-20 2011-05-26 Innovelle, Llc Instrument ou accessoire bariatrique équipé de capteurs
US20130226104A1 (en) * 2012-02-24 2013-08-29 Elwha LLC, a limited liability company of the State of Delaware Devices, systems, and methods to control stomach volume

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080243071A1 (en) * 2007-03-30 2008-10-02 Quijano Rodolfo C Intragastric balloon system and therapeutic processes and products
WO2010045477A2 (fr) * 2008-10-16 2010-04-22 Obalon Therapeutics, Inc. Dispositif occupant un volume intra-gastrique et son procédé de fabrication
WO2011063307A1 (fr) * 2009-11-20 2011-05-26 Innovelle, Llc Instrument ou accessoire bariatrique équipé de capteurs
US20130226104A1 (en) * 2012-02-24 2013-08-29 Elwha LLC, a limited liability company of the State of Delaware Devices, systems, and methods to control stomach volume

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