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WO2019070282A1 - Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation - Google Patents

Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation Download PDF

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Publication number
WO2019070282A1
WO2019070282A1 PCT/US2017/055339 US2017055339W WO2019070282A1 WO 2019070282 A1 WO2019070282 A1 WO 2019070282A1 US 2017055339 W US2017055339 W US 2017055339W WO 2019070282 A1 WO2019070282 A1 WO 2019070282A1
Authority
WO
WIPO (PCT)
Prior art keywords
iol
injector
lumen
cartridge
sleeve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2017/055339
Other languages
English (en)
Other versions
WO2019070282A8 (fr
Inventor
Wen-Chu Tseng
Ming-Yen Shen
William Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AST Products Inc
Original Assignee
AST Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AST Products Inc filed Critical AST Products Inc
Priority to EP17927931.0A priority Critical patent/EP3691570A4/fr
Priority to JP2020519804A priority patent/JP7121798B2/ja
Priority to PCT/US2017/055339 priority patent/WO2019070282A1/fr
Priority to CN201780095064.6A priority patent/CN111212613B/zh
Publication of WO2019070282A1 publication Critical patent/WO2019070282A1/fr
Anticipated expiration legal-status Critical
Publication of WO2019070282A8 publication Critical patent/WO2019070282A8/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/1678—Instruments for inserting intraocular lenses into the eye with a separate cartridge or other lens setting part for storage of a lens, e.g. preloadable for shipping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/1667—Instruments for inserting intraocular lenses into the eye with rotatable plungers

Definitions

  • the invention relates generally to ophthalmic surgical devices and methods, and more particularly to a device and method for inserting an intraocular lens (IOL) into an eye of a patient.
  • IOL intraocular lens
  • Intraocular lens (IOL) injectors are devices designed to insert an IOL into the eye of a patient.
  • Such lenses are surgical implants designed to augment or replace the natural lens of the eye, and are used to treat certain diseases of the eye. For example, the impairment of vision caused by cataracts is often treated by the surgical removal and replacement of the eye's lens.
  • a small 1-4 mm incision is formed in the patient's eye. The surgeon then uses a tool, inserted into the eye through the incision, to emulsify (break up) and remove the eye's natural lens. Once removed an artificial intraocular lens is inserted in the eye.
  • lenses In order to insert the lens without enlarging the incision, lenses are employed which may be compressed or folded, and inserted through an incision, often using an injector device. Once the IOL is in the eye, it is designed to recover to its unfolded shape with a predetermined orientation within the eye. In this process, placement of the IOL is critical, especially for toric lenses used for treatment of astigmatism which require precise positioning and orientation at a predetermined location in the eye. Improper placement requires the surgeon to manually manipulate the IOL positioning which can cause damage to the eye, as well as damage to the IOL.
  • IOLs are typically transported and stored in a relaxed state to avoid damage to the lenses.
  • conventional injector devices require the physician to load the IOL into the injector thereby requiring the physician to exercise a great deal of skill in loading the IOL in the proper orientation while avoiding damage to the IOL.
  • Conventional injector devices provide the physician with no ability to control orientation of a lens during loading and/or during delivery of a lens to the eye. As such, there exists a need for an improved IOL injector which is easier to use while ensuring proper deliver of an IOL to the eye.
  • the present invention addresses the deficiencies of conventional injectors by providing an IOL injector which is optionally preloaded with an IOL in the unfolded state, wherein the injector is configured to automatically fold and properly aligns the IOL during delivery of the IOL without relying on the skill of the physician.
  • the invention provides an IOL injector.
  • the injector includes an injector body elongated along a longitudinal axis having a lumen disposed therein.
  • a lens cartridge is in operable connection with the injector body and includes a lumen configured to receive an IOL and a positioning mechanism for folding and aligning the IOL in the lens cartridge lumen.
  • An injector tip is in operable connection with the lens cartridge, the injector tip having a lumen which terminates in a distal opening.
  • a plunger having an elongated shaft is slidably disposed in the lumen of the injector body.
  • the plunger is configured to contact the folded IOL which is loaded in the lens cartridge lumen and push the IOL along the longitudinal axis through the injector tip lumen and out of the distal opening when the plunger is depressed into a deployed position.
  • the injector further includes a sleeve in operable connection with the lens cartridge.
  • the lens cartridge is configured to mechanically fold the IOL which is preloaded in the lens cartridge and align the IOL within the lens cartridge lumen via the positioning mechanism upon moving the sleeve over the lens cartridge from a distal first position where the sleeve is over the injector tip, to a proximal second position where the sleeve is over the lens cartridge.
  • the positioning mechanism includes a first and second cartridge portion which are mechanically moved toward one another perpendicular to the longitudinal axis of the device thereby folding the IOL when the sleeve is moved over the lens cartridge from the distal first position over the injector tip.
  • the invention provides a method of implanting an IOL using the injector device of the present invention.
  • the method includes providing an IOL injector having an IOL preloaded in the lens cartridge, transitioning the sleeve from the distal first position over the injector tip, to the proximal second position over the lens cartridge thereby folding and aligning the IOL in the lens cartridge lumen, and depressing the plunger to transition it from the undeployed position to the deployed position to push the folded IOL along the longitudinal axis of the device and eject the IOL from the distal opening of the injector tip lumen into the eye of a patient.
  • the invention provides a kit for practicing the method of the invention.
  • the kit includes an IOL injector of the invention and an IOL optionally preloaded in the injector.
  • the injector is preloaded with the IOL such that the sleeve is in the distal first position and the IOL is in an unfolded state in the lens cartridge lumen.
  • Figure 1 is a perspective view of an IOL injector in one embodiment of the invention, wherein the sleeve 60 is in a first position covering the injector tip 40;
  • Figure 2 is a front view of the IOL injector depicted in Figure 1 in one embodiment of the invention.
  • Figure 3 is a back view of the IOL injector depicted in Figure 1 in one embodiment of the invention.
  • Figure 4 is a left side view of the IOL injector depicted in Figure 1 in one embodiment of the invention.
  • Figure 5 is a right side view of the IOL injector depicted in Figure 1 in one embodiment of the invention.
  • Figure 6 is a top view of the IOL injector depicted in Figure 1 in one embodiment of the invention.
  • Figure 7 is a bottom view of the IOL injector depicted in Figure 1 in one embodiment of the invention.
  • Figure 8 is a perspective view of an IOL injector in one embodiment of the invention, wherein the sleeve 60 is in a second position covering the lens cartridge 30;
  • Figure 9 is a front view of the IOL injector depicted in Figure 8 in one embodiment of the invention.
  • Figure 10 is a back view of the IOL injector depicted in Figure 8 in one embodiment of the invention.
  • Figure 11 is a left side view of the IOL injector depicted in Figure 8 in one embodiment of the invention.
  • Figure 12 is a right side view of the IOL injector depicted in Figure 8 in one embodiment of the invention.
  • Figure 13 is a top view of the IOL injector depicted in Figure 8 in one embodiment of the invention;
  • Figure 14 is a bottom view of the IOL injector depicted in Figure 8 in one embodiment of the invention.
  • Figure 15 is an exploded view of an IOL injector in one embodiment of the invention.
  • Figure 16 is an expanded perspective view of the first cartridge portion 34 depicted in Figure 15 in one embodiment of the invention.
  • Figure 17 is an expanded perspective view of the second cartridge portion 36 depicted in Figure 15 in one embodiment of the invention.
  • Figure 18 is an expanded top perspective view of the injector body 20 and lens cartridge 30 depicted in Figure 15 in one embodiment of the invention
  • Figure 19 is an expanded bottom perspective view of the injector body 20 and lens cartridge 30 depicted in Figure 15 in one embodiment of the invention.
  • Figure 20 is an expanded perspective view of the sleeve 60 depicted in Figure 15 in one embodiment of the invention.
  • Figure 21 is a front view of the injector tip 40 depicted in Figure 15 in one embodiment of the invention.
  • Figure 22 is an expanded top view of the IOL injector depicted in Figure 1 in one embodiment of the invention illustrating the distal region of the IOL injector.
  • the present invention provides a device and method for inserting an IOL into an eye of a patient.
  • the IOL injector is configured to automatically load an IOL into the injector by folding and aligning the IOL into a lens cartridge of the injector without manual manipulation of the IOL by the physician during the procedure.
  • the injector is configured to properly orient and align the IOL within the injector and maintain proper alignment throughout delivery of the IOL to the eye of a patient and thereby ensuring that the IOL is properly positioned and oriented at a predetermined location in the eye.
  • one such IOL injector 10 includes an injector body 20, a lens cartridge 30 in operable connection with the injector body, an injector tip 40 in operable connection with the lens cartridge, a plunger 50, and sleeve 60 in operable connection with the lens cartridge.
  • Figure 15 is an exploded view showing the operable association of the components of the IOL injector.
  • the plunger 50, the injector body 20, the lens cartridge 30, the injector tip 40 and sleeve 60 are arranged along a longitudinal axis of the IOL injector with the plunger being disposed on the proximal end of the injector and the injector tip 40 being disposed on the distal end of the injector.
  • a lumen traverses the entire length of the device such that an IOL loaded into the lens cartridge lumen 32 can be pushed by the distal tip 56 of the elongated shaft 52 of the plunger 50 along the longitudinal axis through the injector tip lumen 42, and out of the distal opening 44 into a patient's eye, when the plunger 50 is advanced distally from an undeployed position to a deployed position.
  • the injector is configured to mechanically fold and align the IOL within the lens cartridge such that the proper orientation is achieved upon loading of the IOL into the lens cartridge lumen as well as delivery to the eye. Folding and aligning of the IOL in the lens cartridge lumen is achieved via a positioning mechanism disposed in the lens cartridge 30 which is in operable connection to the sleeve 60.
  • Transitioning the sleeve 60 from a first position in which the sleeve 60 covers the injector tip 40 as shown in Figures 1 to 7, to a second position in which the sleeve 60 covers the lens cartridge 30 as shown in Figures 8 to 14, causes the positioning mechanism to fold the IOL from a first unfolded state to a second folded state and align the IOL within the lens cartridge lumen 32.
  • the IOL may be delivered to a patient's eye by advancing the plunger 50 distally from an undeployed position to a deployed position.
  • the positioning mechanism may include one or more components that operably associate to fold the IOL and interact with the sleeve 60.
  • Figure 15 illustrates an embodiment of the injector which includes a positioning mechanism having a first cartridge portion 34 and a second cartridge portion 36.
  • the first cartridge portion 34 and the second cartridge portion 36 are illustrated in Figures 16 and 17, respectively.
  • the first cartridge portion 34 has a surface adapted to contact an internal surface of the sleeve and urge the first cartridge portion toward the second cartridge portion 36 when the sleeve 60 is moved from the first position to the second position.
  • surface 38 is configured to contact the internal surface of sleeve 60 as it moves from the first position to the second position.
  • the surface 38 has a distal tapered region 39 which facilitates contact with the internal surface of the sleeve 60 as it is moved over the lens cartridge 30.
  • the injector is configured to position one or more of the haptics on the optic region of the IOL in the correct orientation for delivery.
  • a properly aligned IOL has a leading haptic pushed toward the optic and a trailing haptic contacting the distal tip 56 of the plunger 50.
  • a properly oriented IOL has the haptics "tagged" to the optical area.
  • the distal tip 56 includes a polymeric material such as silicone, or other resiliently deformable polymer.
  • one or more raised ridge surfaces may be disposed on the internal surface of the sleeve.
  • Figure 20 depicts an embodiment in which the internal surface of the sleeve includes multiple ridges 65 for interacting with corresponding grooves disposed on the lens cartridge 30.
  • Figure 19 illustrates an embodiment of a lens cartridge 30 having grooves 70 for receiving ridges disposed on the internal surface of the sleeve.
  • the IOL injector is provided in a kit along with an IOL which is optionally preloaded in the lens cartridge of the injector.
  • providing the injector in a preloaded state allows that injector to be sterilized with the IOL simultaneously at the factory during packaging.
  • the lens injector is provided with the IOL preloaded in the lens cartridge whereby the lens is in an unfolded state, the sleeve is in the first position covering the injector tip, and the plunger is in the undeployed state.
  • the physician simply needs to unpack the injector, transition the sleeve from the first position to the second position to fold and align the IOL in the lens cartridge, and deliver the IOL to the patient's eye by transitioning the plunger from the undeployed position to the deployed position.
  • the IOL injector may be configured for single use such that the injector is discarded after delivery of the IOL to the eye.
  • the invention provides a method of implanting an IOL into the eye of a patient.
  • the method includes providing an IOL injector of the invention having an IOL preloaded in the lens cartridge, transitioning the sleeve from the distal first position over the injector tip to the proximal second position over the lens cartridge thereby folding and aligning the IOL in the lens cartridge lumen, and depressing the plunger to transition it from the undeployed position to the deployed position to push the folded IOL along the longitudinal axis of the device and eject the IOL from the distal opening of the injector tip lumen into the eye of a patient.
  • the injector can be configured such that the sleeve can be locked in the second position.
  • the injector may include a locking mechanism which prevents movement of the sleeve from transitioning from the second position to the first position. This can be accomplished in a number of ways as will be appreciated by one in the art.
  • the locking mechanism may include a snap lock wherein the sleeve includes one or more locking structures which snap into corresponding recesses disposed on the lens cartridge.
  • the lumen extending along the longitudinal axis of the injector need not have a constant diameter. In embodiments, the lumen has a different diameter in different regions of the injector.
  • the lens cartridge lumen may have a different diameter than the injector tip lumen.
  • the diameter of the lens cartridge lumen is greater than the diameter of the injector tip lumen.
  • the injector tip lumen tapers from a larger diameter at the proximal end of the injector tip to a smaller diameter at the distal end of the injector tip where the distal opening is located.
  • the cross-sectional area of the injector tip lumen decreases from a larger diameter at the proximal end of the injector tip to a smaller diameter at the distal end of the injector tip where the distal opening is located. Additionally, the cross-sectional shape of the injector tip lumen may be different at the distal end of the injector tip lumen as compared to the proximal end of the injector tip lumen.
  • Figure 21 is a front view of an injector tip 40 showing an embodiment in which the distal opening 44 has an elongated circular cross-sectional shape.
  • the cross-sectional shape of the distal opening can be any shape necessary to maintain proper folding and orientation of the IOL for delivery to the eye. This may depend in part on the type and shape of the IOL being delivered.
  • the cross-sectional shape of the distal opening can be square, round, ellipse, rectangle, triangle or curvilinear triangle.
  • the IOL injector may be constructed using a variety of different materials.
  • different components of the injector may be constructed from different materials to impart different structural characteristics in different regions of the device.
  • various regions of the delivery lumen may include a polymer or lubricious coating.
  • Some embodiments of the present invention may provide IOL injectors with components constructed partially or entirely of polyurethane polymers; styrene related copolymers, such as but not limited to, polyolefin, polyamide, PEBAX, acrylic butyldiene styrene (ABS), styrene butyldiene styrene (SBS), and/or high impact polystyrene (HIPS); polyester polymers; and polymeric blends or copolymers thereof.
  • styrene related copolymers such as but not limited to, polyolefin, polyamide, PEBAX, acrylic butyldiene styrene (ABS), styrene butyldiene styrene (SBS), and/or high impact polystyrene (HIPS); polyester polymers; and polymeric blends or copolymers thereof.
  • ABS acrylic butyldiene styrene
  • SBS styrene
  • the delivery lumen In order to ensure that the IOL is able to traverse the delivery lumen without causing damage to the lumen and/or the IOL, the delivery lumen should be able to withstand the application of the forces it will encounter during insertion. Accordingly, the delivery lumen may be formed from materials of sufficient toughness to withstand those forces without cracking or rupturing. In addition, in order to reduce the risk of damage to the IOL, and also reduce the insertion forces needed to perform the insertion, the delivery lumen may be formed of sufficiently lubricious material, be compounded with lubricating additives, be coated with a lubricating material, or otherwise minimize the forces tending to bind the IOL to the interior wall of the lumen. These considerations are especially true for the distal end of the injector tip since the tapering of the delivery lumen increases normal forces experienced by the delivery lumen as the IOL is moved distally.
  • a coating made of a hydrophilic polymeric material may be applied to the delivery lumen or lens cartridge to provide additional lubricity.
  • a coating may include one or more hydrophilic polymeric materials, such as but not limited to, hydrophilic polyurethane, polyvinylpyrrolidone, polyacrylic acid, polyacrylamides, polyhydroxyethyl methacrylate, and/or hyaluronan, or the like. It is noted, however, that the lubricants used in the delivery lumen need not be applied uniformly along the lumen.
  • some embodiments may utilize material formed using a co-molding process.
  • two or more materials e.g. polymers
  • materials may be extruded and/or injected to form a single piece, and may allow for the use of materials having different physical properties.
  • materials may be used having both sufficient toughness and other desirable properties.
  • a polyurethane may be used having sufficient toughness, while another polyurethane may be used having desirable lubrication properties.
  • the injector is constructed using polymer compositions having engrafted hydrophilic and lubricious groups as described in U.S. Patent Application No. 2013/0129953 to Lee which is incorporated herein by reference.
  • Such compositions utilize polypropylene, polycarbonate, polyamide, cellulose acetate, and acrylic polymer or copolymer which are suitable base polymers for engrafting.
  • IOLs intraocular lenses
  • the 30 hydrophobic foldable single-piece intraocular lenses were consisted of IOLs of 10 low, 10 medium and 10 high diopters. All lenses were delivered through the injector of the present invention according to the loading and delivery procedure in the instructions for use.
  • the IOLs were evaluated for the optical properties, sagitta, and overall surface and bulk homogeneity before and after being surgically manipulated using the injector of the present invention, as well as lens opening time after folding.
  • the injector of the present invention was also evaluated for its cartridge and tip performance, such as overall cartridge and tip surface and bulk homogeneity.
  • IOL optical properties and overall surface and bulk homogeneity inspection were conducted in accordance with ISO 11979-2, Ophthalmic implants - Intraocular lenses - Part 2: Optical properties and test methods and ISO 11979-3, Ophthalmic implants - Intraocular lenses - Part 3 : Mechanical properties and test methods.
  • IOLs intraocular lenses
  • the 30 hydrophilic foldable single-piece intraocular lenses were consisted of IOLs of 10 low, 10 medium and 10 high diopters. All lenses were delivered through the injector of the present invention according to the loading and delivery procedure in the instructions for use.
  • the IOLs were evaluated for the optical properties, sagitta, and overall surface and bulk homogeneity before and after being surgically manipulated using the injector of the present invention, as well as lens opening time after folding.
  • the injector of the present invention was also evaluated for its cartridge and tip performance, such as overall cartridge and tip surface and bulk homogeneity.
  • IOL optical properties and overall surface and bulk homogeneity inspection were conducted in accordance with ISO 11979-2, Ophthalmic implants - Intraocular lenses - Part 2: Optical properties and test methods and ISO 11979-3, Ophthalmic implants - Intraocular lenses - Part 3 : Mechanical properties and test methods.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

La présente invention concerne un dispositif et une méthode pour insérer une LIO dans l'œil d'un patient. L'injecteur de LIO est configuré pour charger automatiquement une LIO dans l'injecteur par pliage et alignement de la LIO dans une cartouche de lentille de l'injecteur sans manipulation manuelle de la LIO par le médecin pendant la procédure. L'injecteur est configuré pour orienter et aligner correctement la LIO à l'intérieur de l'injecteur et maintenir un alignement correct pendant l'administration de la LIO à l'œil d'un patient et garantir ainsi que la LIO est correctement positionnée et orientée à un emplacement prédéterminé dans l'œil.
PCT/US2017/055339 2017-10-05 2017-10-05 Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation Ceased WO2019070282A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP17927931.0A EP3691570A4 (fr) 2017-10-05 2017-10-05 Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation
JP2020519804A JP7121798B2 (ja) 2017-10-05 2017-10-05 眼内レンズ（ｉｏｌ）インジェクター及びその使用方法
PCT/US2017/055339 WO2019070282A1 (fr) 2017-10-05 2017-10-05 Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation
CN201780095064.6A CN111212613B (zh) 2017-10-05 2017-10-05 人工晶状体(iol)注射器及其使用方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2017/055339 WO2019070282A1 (fr) 2017-10-05 2017-10-05 Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation

Publications (2)

Publication Number Publication Date
WO2019070282A1 true WO2019070282A1 (fr) 2019-04-11
WO2019070282A8 WO2019070282A8 (fr) 2020-04-23

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PCT/US2017/055339 Ceased WO2019070282A1 (fr) 2017-10-05 2017-10-05 Injecteur de lentille intraoculaire (lio) et sa méthode d'utilisation

Country Status (4)

Country Link
EP (1) EP3691570A4 (fr)
JP (1) JP7121798B2 (fr)
CN (1) CN111212613B (fr)
WO (1) WO2019070282A1 (fr)

Cited By (1)

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WO2024180106A1 (fr) * 2023-03-01 2024-09-06 Carl Zeiss Meditec Ag Ensemble d'emballage ayant un injecteur pour introduire une lentille intraoculaire dans le sac capsulaire d'un œil

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JP2025172489A (ja) * 2024-05-13 2025-11-26 ホヤ メディカル シンガポール ピーティーイー エルティーディー 眼内レンズ挿入器

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US20050049606A1 (en) * 2003-08-28 2005-03-03 Edward Vaquero Preloaded IOL injector
US20090131953A1 (en) * 2005-01-21 2009-05-21 Nicolas Quintin Flexible Intraocular Implant Injector
US20090312767A1 (en) 2008-06-11 2009-12-17 Pollock David P Intraocular Lens Injector and Method
US20100106160A1 (en) * 2008-10-24 2010-04-29 George Tsai Intraocular lens injection systems and methods
US20100256651A1 (en) * 2009-04-07 2010-10-07 Dharmendra Jani Intraocular Lens Injector with Hydrophilic Coating
US20130129953A1 (en) 2010-10-06 2013-05-23 Ast Products, Inc. Functionalized hydrophilic and lubricious polymeric matrix and methods of using same
WO2015075488A1 (fr) 2013-11-20 2015-05-28 Medicontur Orvostechnikai Kft. Injecteur préchargé comprenant un élément rotatif pour le stockage et l'injection de lentilles intra-oculaires hydrophobes
US20160074156A1 (en) * 2013-05-21 2016-03-17 Carl Zeiss Meditec Ag Cassette for receiving an intraocular lens, injector device having said cassette and method for folding an intraocular lens in a cassette

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GB2470416A (en) * 2009-05-22 2010-11-24 Rayner Intraocular Lenses Ltd Intraocular Lens Cartridge
US8696682B2 (en) * 2010-04-02 2014-04-15 Abbott Medical Optics Inc. Intraocular lens insertion devices
US9999499B2 (en) * 2012-09-04 2018-06-19 Carl Zeiss Meditec Production, LLC Preloaded intraocular lens (IOL) system and method
US9155615B2 (en) * 2012-11-09 2015-10-13 Bausch & Lomb Incorporated Hingeless cartridge for use with an intraocular lens injector providing haptic control
US9636216B2 (en) * 2013-04-19 2017-05-02 Staar Surgical Company Injector cartridge with improved lubricity

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494484A (en) * 1992-09-30 1996-02-27 Staar Surgical Company Deformable intraocular lens injecting device
US20050049606A1 (en) * 2003-08-28 2005-03-03 Edward Vaquero Preloaded IOL injector
US20090131953A1 (en) * 2005-01-21 2009-05-21 Nicolas Quintin Flexible Intraocular Implant Injector
US20090312767A1 (en) 2008-06-11 2009-12-17 Pollock David P Intraocular Lens Injector and Method
US20100106160A1 (en) * 2008-10-24 2010-04-29 George Tsai Intraocular lens injection systems and methods
US20100256651A1 (en) * 2009-04-07 2010-10-07 Dharmendra Jani Intraocular Lens Injector with Hydrophilic Coating
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EP3691570A1 (fr) 2020-08-12
JP7121798B2 (ja) 2022-08-18
CN111212613B (zh) 2023-01-20
JP2021502133A (ja) 2021-01-28
CN111212613A (zh) 2020-05-29
WO2019070282A8 (fr) 2020-04-23
EP3691570A4 (fr) 2021-05-05

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