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WO2019059872A3 - Ivermectin topical formulation - Google Patents

Ivermectin topical formulation Download PDF

Info

Publication number
WO2019059872A3
WO2019059872A3 PCT/TR2018/050519 TR2018050519W WO2019059872A3 WO 2019059872 A3 WO2019059872 A3 WO 2019059872A3 TR 2018050519 W TR2018050519 W TR 2018050519W WO 2019059872 A3 WO2019059872 A3 WO 2019059872A3
Authority
WO
WIPO (PCT)
Prior art keywords
topical formulation
ivermectin
ivermectin topical
rosacea
formulated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/TR2018/050519
Other languages
French (fr)
Other versions
WO2019059872A2 (en
Inventor
Mehmet Koray GÜRBÜZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Assos Ilac Kimya Gida Ueruenleri Ueretim Ve Tic AS
Original Assignee
Assos Ilac Kimya Gida Ueruenleri Ueretim Ve Tic AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Assos Ilac Kimya Gida Ueruenleri Ueretim Ve Tic AS filed Critical Assos Ilac Kimya Gida Ueruenleri Ueretim Ve Tic AS
Publication of WO2019059872A2 publication Critical patent/WO2019059872A2/en
Publication of WO2019059872A3 publication Critical patent/WO2019059872A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to ivermectin topical formulation for use in the treatment of rosacea. Ivermectin is formulated to be active in the oil phase to improve hydrolytic stability.
PCT/TR2018/050519 2017-09-22 2018-09-22 Ivermectin topical formulation Ceased WO2019059872A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2017/14097 2017-09-22
TR2017/14097A TR201714097A2 (en) 2017-09-22 2017-09-22 IVERMEKTIN TOPIC FORMULATION

Publications (2)

Publication Number Publication Date
WO2019059872A2 WO2019059872A2 (en) 2019-03-28
WO2019059872A3 true WO2019059872A3 (en) 2019-06-20

Family

ID=65811450

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2018/050519 Ceased WO2019059872A2 (en) 2017-09-22 2018-09-22 Ivermectin topical formulation

Country Status (2)

Country Link
TR (1) TR201714097A2 (en)
WO (1) WO2019059872A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150306027A1 (en) * 2003-04-24 2015-10-29 Galderma S.A. Topical application of ivermectin for the treatment of dermatological conditions/afflictions
US20160303152A1 (en) * 2015-04-15 2016-10-20 Gavis Pharmaceuticals Topical Composition of Ivermectin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150306027A1 (en) * 2003-04-24 2015-10-29 Galderma S.A. Topical application of ivermectin for the treatment of dermatological conditions/afflictions
US20160303152A1 (en) * 2015-04-15 2016-10-20 Gavis Pharmaceuticals Topical Composition of Ivermectin

Also Published As

Publication number Publication date
TR201714097A2 (en) 2018-10-22
WO2019059872A2 (en) 2019-03-28

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