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WO2018131010A3 - Dynamic chamber for in vitro permeability assays - Google Patents

Dynamic chamber for in vitro permeability assays Download PDF

Info

Publication number
WO2018131010A3
WO2018131010A3 PCT/IB2018/052688 IB2018052688W WO2018131010A3 WO 2018131010 A3 WO2018131010 A3 WO 2018131010A3 IB 2018052688 W IB2018052688 W IB 2018052688W WO 2018131010 A3 WO2018131010 A3 WO 2018131010A3
Authority
WO
WIPO (PCT)
Prior art keywords
dynamic chamber
vitro permeability
permeability assays
assays
refers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2018/052688
Other languages
French (fr)
Other versions
WO2018131010A2 (en
Inventor
Antonio ARIAS
Audino MONTENEGRO
Sebastian VELARDE
Christian GÓMEZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Absorption Systems
Original Assignee
Absorption Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Absorption Systems filed Critical Absorption Systems
Publication of WO2018131010A2 publication Critical patent/WO2018131010A2/en
Publication of WO2018131010A3 publication Critical patent/WO2018131010A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0609—Holders integrated in container to position an object
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/006—Dissolution of tablets or the like
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/08—Investigating permeability, pore-volume, or surface area of porous materials
    • G01N2015/0813—Measuring intrusion, e.g. of mercury

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention refers to a permeability dynamic chamber with a cylindrical shape having a rounded bend at its bottom together with a filter coupled by means of magnet fixing and protrusions at the sides thereof. Furthermore, the invention also refers to a gastrointestinal simulating device for in vitro permeability assays comprising a dynamic chamber being coupled thereto, in a set of four, to the cover of a standard dissolution vessel.
PCT/IB2018/052688 2018-04-13 2018-04-18 Dynamic chamber for in vitro permeability assays Ceased WO2018131010A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PA9210301 2018-04-13
PA92103 2018-04-13

Publications (2)

Publication Number Publication Date
WO2018131010A2 WO2018131010A2 (en) 2018-07-19
WO2018131010A3 true WO2018131010A3 (en) 2018-10-25

Family

ID=62840282

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2018/052688 Ceased WO2018131010A2 (en) 2018-04-13 2018-04-18 Dynamic chamber for in vitro permeability assays

Country Status (1)

Country Link
WO (1) WO2018131010A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020176800A1 (en) * 2001-05-09 2002-11-28 Henry Richard A. Curved miniature liquid chromatography column
US20090165578A1 (en) * 2007-12-06 2009-07-02 Pain Therapeutics, Inc. Dissolution test equipment and methods for testing
US8434378B2 (en) * 2010-04-12 2013-05-07 Distek, Inc. Dissolution-testing vessel cover
US20140287487A1 (en) * 2013-03-19 2014-09-25 Rarecyte, Inc. Device, systems and methods for analyzing a target analyte
US20150136140A1 (en) * 2009-11-19 2015-05-21 Resmed Motor Technologies Inc Blower

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020176800A1 (en) * 2001-05-09 2002-11-28 Henry Richard A. Curved miniature liquid chromatography column
US20090165578A1 (en) * 2007-12-06 2009-07-02 Pain Therapeutics, Inc. Dissolution test equipment and methods for testing
US20150136140A1 (en) * 2009-11-19 2015-05-21 Resmed Motor Technologies Inc Blower
US8434378B2 (en) * 2010-04-12 2013-05-07 Distek, Inc. Dissolution-testing vessel cover
US20140287487A1 (en) * 2013-03-19 2014-09-25 Rarecyte, Inc. Device, systems and methods for analyzing a target analyte

Also Published As

Publication number Publication date
WO2018131010A2 (en) 2018-07-19

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