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WO2018124463A2 - Système de gestion et de mesure de dosage de type à montage universel pour dispositif d'injection de type stylo - Google Patents

Système de gestion et de mesure de dosage de type à montage universel pour dispositif d'injection de type stylo Download PDF

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Publication number
WO2018124463A2
WO2018124463A2 PCT/KR2017/012828 KR2017012828W WO2018124463A2 WO 2018124463 A2 WO2018124463 A2 WO 2018124463A2 KR 2017012828 W KR2017012828 W KR 2017012828W WO 2018124463 A2 WO2018124463 A2 WO 2018124463A2
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WO
WIPO (PCT)
Prior art keywords
pen
dose
measurement
injection device
slide rod
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Ceased
Application number
PCT/KR2017/012828
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English (en)
Korean (ko)
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WO2018124463A3 (fr
Inventor
최규동
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Individual
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Individual
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Publication of WO2018124463A2 publication Critical patent/WO2018124463A2/fr
Publication of WO2018124463A3 publication Critical patent/WO2018124463A3/fr
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Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms

Definitions

  • the present invention relates to a universally mounted dose measurement and management system of a pen-type injection device, comprising: a housing of the pen-type injection device (1) in an injection amount measurement and management system mounted on the pen-type injection device (1) to measure the dose of a drug;
  • the main body 110 detachably coupled to the clip-on mounting portion 120 through the (10); And, installed on the main body 110, to the rotation of the dose knob 12 of the pen-type injection device (1)
  • the main control unit 150 to manage and display a; It relates to a universally mounted dose measurement and management system 100 of a pen-type injection device, characterized in that comprising a
  • insulin which is a drug for treating diabetic metabolic disease
  • the meal-type insulin is usually injected into the human body three times a day on an empty stomach before meals to prevent a rapid rise in blood sugar levels of the diabetic metabolic disease after eating, and the basic insulin gradually decreases the action of insulin in the body for 24 hours. It is insulin that is maintained.
  • diabetes is a disease that occurs when the body does not make enough insulin or does not use insulin properly to convert blood sugar, ie, glucose into energy.
  • blood sugar ie, glucose into energy.
  • it should be injected at a predetermined time, so it is more important to inject insulin at a fixed time than to inject a dose.
  • the infusion device includes a cartridge mounting portion in which a cartridge filled with insulin is mounted, and a pusher for pushing the cartridge to eject insulin through a discharge portion and injecting the same into a patient.
  • Such a portable injection device is commonly referred to as an "insulin pen” and has advantages such as easy and convenient injection while going out compared to an insulin syringe, and injecting an accurate amount of use with a simple dial operation.
  • an insulin pen As a prior patent document relating to such an insulin pen, a number of patent documents have been published, including "a pen-type drug injection device equipped with a dose setting and resetting mechanism (Korean Patent Publication No. 10-2016-0049538)".
  • the insulin pump is a medical device that acts as a pancreas, attached to the patient's outside of the body to properly supply insulin to maintain normal blood sugar, and in the meantime, to restore the pancreatic function.
  • Insulin pumps inject insulin subcutaneously for 24 hours in a more sophisticated manner than insulin pens.
  • Such insulin pumps have been disclosed in a number of patent documents, including "automatically controlled insulin pumps with sensors (Korean Patent No. 10-0723808).”
  • Such an insulin pump has a problem that it is difficult to be widely used because the device is relatively complicated and expensive.
  • the present invention solves the problems of the existing invention, it is possible to install both in a disposable or reusable pen-type injection device having a variety of specifications, sizes, shapes, etc., as well as to accurately measure the dosage of the drug and
  • An object of the present invention is to provide a universally mounted dose measurement and management system for a pen-type injection device capable of systematically managing a dose history such as a dose time.
  • the operating range can be set by measuring the zero point reference point and the maximum position, and the general-purpose mounted dose of the pen-type injection device that enables more accurate dosage measurement
  • the task is to provide a measurement and management system.
  • the pen-type injection device capable of more accurately measuring the dosage and systematically managing the effective injection history It is an object of the present invention to provide a universally mounted input measurement and management system.
  • the universally mounted dose measurement and management system of the pen-type injection device of the present invention is a pen-type injection device in the dose measurement and management system mounted on the pen-type injection device 1 to measure the dose of a drug.
  • the main body 110 is detachably coupled to the housing 10 of the (1) through the clip-on mounting portion 120; And, installed in the main body 110, the dose knob of the pen-type injection device ( A measurement slide rod 130 that moves together with the forward or backward of the dose knob 12 in association with the forward or backward of the rotation of 12); and a measurement slide for sensing the position of the measurement slide rod 130.
  • the main control unit 150 to manage and display the injection history information; Characterized in that comprises a.
  • the measuring slide rod 130 is provided in the main body 110, the elastic providing means 131 for providing an elastic force in the main body direction with respect to the measuring slide rod 130; and the measuring slide rod It is formed on the upper end of the 130, in close contact with the upper end of the dose knob 12 by the elasticity providing means 131, in conjunction with the forward or backward of the dose knob 12 A dose knob contact 132 for causing the measurement slide rod 130 to move forward or backward; Characterized in that further comprises.
  • the dose knob contact portion 132 further includes an injection button passage portion 132a through which the injection button 11 can pass, and the measurement slide rod 130 includes the injection button.
  • (11) is configured to further include an injection detection sensor 133 that can sense the state pressed in the input process, the main control unit 150, the injection button 11 through the injection detection sensor 133
  • the drug dosage is calculated by changing the position of the measurement slide rod 130 measured by the measurement slide rod position detection sensor 140 while being detected as being pressed.
  • the clip-on mounting portion 120 a housing mounting space portion 121 through which the housing 10 can be inserted; and a fixing band 125 that can be fixed to each other while surrounding the housing 10; Characterized in that further comprises.
  • the dose knob contact portion 132 characterized in that it further comprises a mounting arm (132c, 132d) that can be opened to each other through the hinge portion (132b) according to the outer diameter of the injection button (11) do.
  • main control unit 150 input and output interface 160 for receiving a user's operation input and display the operation status; and connected to the main control unit 170, the user terminal through the communication network (N)
  • a wireless communication unit 170 connected to any one or more of the medical care server server 300 and the caregiver terminal 400 to transmit the injection history information; Characterized in that further comprises.
  • the user terminal 200 is characterized in that it further comprises a camera 210, the user terminal 200, of the pen-type scanning device 1 photographed through the camera 210
  • the ampoule information regarding the type and dose of the drug injected according to the housing or the captured image of the insulin container 14 is extracted and transmitted to the main controller 150 through the wireless communication unit 170.
  • an advantage is that it is possible to provide a universally mounted dose measuring and management system of a pen-type injection device capable of systematically managing the feeding history.
  • the operating range can be set by measuring the zero point reference point and the maximum position, and the general-purpose mounted dose of the pen-type injection device that enables more accurate dosage measurement.
  • the pen-type injection device capable of more accurately measuring the dosage and systematically managing the effective injection history
  • the pen-type injection device capable of more accurately measuring the dosage and systematically managing the effective injection history
  • FIG. 1 is a view showing the configuration of a pen-type injection device according to an embodiment of the existing invention.
  • FIG 3 is an external view of a universally mounted dose measuring and management system of a pen-type injection device according to an embodiment of the present invention.
  • FIG. 4 is a block diagram of a universally mounted dose measuring and management system of a pen-type injection device according to an embodiment of the present invention.
  • FIG. 5 is a schematic diagram showing a linear process of a universally mounted dose measurement and management system of a pen-type injection device according to an embodiment of the present invention.
  • FIG. 6 is a schematic diagram illustrating a case where a universally mounted dose measuring and management system of a pen-type injection device according to an embodiment of the present invention is mounted on pen-type injection devices of various sizes.
  • FIG. 7 A diagram showing the mounting state of the dose knob contact portion of the universally mounted dose measurement and management system of the pen-type injection device according to an embodiment of the present invention.
  • a dose knob contact portion of a universally mounted dose measurement and management system of a pen-type injection device according to one embodiment of the present invention is shown in the case where the injection button of various sizes is mounted.
  • FIG. 9 is a flow chart showing the operation of the universally mounted dose measuring and management system of the pen-type injection device according to one embodiment of the present invention.
  • Needle 16 Internal Needle Cap
  • 132b hinge portion 132c
  • 132d mounting arm
  • the pen-type injection device 1 may have a variety of specifications, sizes, shapes, etc. as described above, and may be classified as disposable or reusable. In terms of scanning, they have something in common.
  • FIG. 1 is an exploded view of, for example, a Sanofi Solostar (R), an exploded view of a pen-type injection device 1 that can represent an insulin injection pen.
  • R Sanofi Solostar
  • the pen-shaped injection device 1 of FIG. 1 is a pre-filled, disposable injection pen with a housing 10 and equipped with an insulin container 14 to which the needle 15 can be fixed.
  • the needle is protected by an inner needle cap 16 and an outer needle cap 17, and consequently can be covered by the cap 18.
  • the dose of insulin discharged from the pen-shaped injection device 1 can be selected by turning the dose knob 12, which dose is, for example, a dose display in the form of a multiple of so-called international units (IU) or Shown via display 13, where 1 IU is the biological equivalent of about 45.5 micrograms of pure crystalline insulin (1/22 mg).
  • An example of a selected dose displayed in the dose indication window or display 13 may be, for example, 30 IU as shown in FIG. 1.
  • the selected dose may be displayed differently, for example by an electronic display. It will be appreciated that the dosage display relates to the portion of the injection device in which the selected dosage can be visually seen through or over it.
  • Turning dose knob 12 generates a mechanical click sound to give the user acoustic feedback.
  • the numbers shown in the dose indication window or display 13 are printed on the sleeve, which is housed in the housing 10 and mechanically interacts with the piston in the insulin container 14.
  • the process of setting the dose by turning the dose knob 12 can both increase or decrease the dose, in which case the sleeve rises or falls with the rotation of the dose knob 12.
  • the scanning liquid is not discharged in a state where the scanning button 11 is not pressed.
  • the needle 15 is inserted into the skin portion of the patient, and then the injection button 11 is pressed, the injection button 11 is pushed in a predetermined distance and then advanced together with the sleeve, and the insulin dose displayed on the display 13 is finally injected. It is discharged from (1). After the injection button 11 is pressed, if the needle 15 of the injection device 1 remains inside the skin portion for a certain time, a large amount of dose is actually injected into the patient's body. Mechanical click sounds also occur when the insulin dose is dispensed, but this is different from the sound produced when using the dosage knob 12.
  • the injection device 1 can be used for several injection procedures until the insulin container 14 is empty or until the expiration date of the injection device 1 (eg 28 days after first use).
  • the universally mounted dose measurement and management system of the pen-type injection device according to an embodiment of the present invention as shown in Figure 3 and 4, the main body 110, the clip-on mounting portion 120, the measurement slide rod 130, measurement The slide rod position detection sensor 140 and the main control unit 150 is characterized in that it is configured.
  • the main body 110 is configured to be detachably coupled to the housing 10 of the pen-type injection device 1 through the clip-on mounting unit 120.
  • the clip-on mounting part 120 is provided with a housing mounting space 121 through which the housing 10 can be retracted.
  • the clip-on mounting part 120 may be made of a material having elasticity so that the clip-on mounting part 120 may be mounted on the housing 10 having various diameters.
  • the clip-on mounting portion 120 is mounted in close contact with the housing 10 of various diameters, to prevent the main body 110 to move relative to the housing 10 during operation, Figure 3 and As shown in Fig. 6, the elastic member 122 is preferably attached to the inner side.
  • the clip-on mounting portion 120 is more firmly mounted to prevent the main body 110 from moving relative to the housing 10 during operation, as shown in Figure 3 and 6
  • it further comprises a fixing band 125 that can be fixed to each other while wrapping (10).
  • the fixing band 125 has a loop and a hook (loop & hook, trade name "Velcro (Velcro)). It is possible to implement using "is more widely known.”
  • the fixing band 125 may be implemented such that the portions overlapping and fixing with each other have magnetic properties having different polarities from each other.
  • the measuring slide rod 130 is installed in the main body 110 as shown in FIG. 3, and rotates the dose knob 12 of the pen-type injection device 1 as indicated by the black arrow in FIG. 5. It is configured to move with the forward or backward of the dose knob 12 in conjunction with the forward or backward according to.
  • the measurement slide rod 130 As shown in FIG. 4, the inside of the main body 110 is preferably provided, and further includes an elastic providing means 131 for providing an elastic force in the main body direction with respect to the measurement slide rod 130.
  • the measurement slide rod 130 of the measurement slide rod 130 in order to be able to operate more efficiently in conjunction with the forward or backward of the dose knob 12. It is formed in the upper end portion, the elastic providing means 131 is in close contact with the upper end of the dose knob 12, in contact with the forward or backward of the dose knob 12, the measurement slide rod ( It is preferably configured to further include a dose knob contact 132 that allows 130 to move forward or backward.
  • the dose knob contact portion 132 is preferably configured to further include an injection button passage portion 132a through which the injection button 11 can pass.
  • the sleeve is raised or lowered according to the rotation of the dose knob 12, but the injection liquid is not discharged in the state that the injection button 11 is not pressed (thus, In the process of setting the dosage, the dosage can be reset as much as possible), the needle 15 is inserted into the skin part of the patient, and then the injection button 11 is pressed, and the injection button 11 is pressed in a predetermined distance. It is then advanced with the sleeve and the insulin dose displayed on the display 13 is finally discharged from the injection device 1.
  • the measurement slide rod 130 is the injection button 11 as shown in FIGS. 3 and 4 so that only the actually administered drug dose can be accurately measured.
  • the dose knob contact portion 132 is hinged according to the outer diameter of the injection button 11, as shown in Figure 8 so that it can be universally corresponding to the injection button 11 of various sizes and standards It is preferable to further include a mounting arm (132c, 132d) that can be opened to each other through (132b).
  • the measurement slide rod position detection sensor 140 As shown in FIG. 4, the measurement slide rod position detection sensor 140 is installed inside the main body 110, and measures the position of the measurement slide rod 130.
  • the measurement slide rod position sensor 140 may be implemented through a wide variety of embodiments, such as mechanical, electrical or optical sensors. As described above, since the technology for implementing the measurement slide rod position detection sensor 140 for detecting and measuring the position of the measurement slide rod 130 is a level of technology widely known and practiced in the field of measurement technology, a detailed description thereof will be omitted. do.
  • the main controller 150 may administer the drug set in the dose knob 12 through the position variation of the measurement slide rod 130 measured by the measurement slide rod position sensor 140. It is configured to calculate the amount to manage and display the injection history information. That is, the drug dosage is directly proportional to the positional variation of the measurement slide rod 130 during the administration. Therefore, by measuring the positional change of the measurement slide rod 130 from the start of administration to the end of administration, it is possible to calculate the drug dosage based on this.
  • the main control unit 150 stores and manages the infusion history information including each drug dose and infusion time so that the history management can be performed in the case of a diabetic agent in which systematic and cumulative administration history is important. It is desirable to.
  • the main controller 150 may further be connected to an input / output interface 160 that receives a user's operation input and displays an operation state.
  • the input / output interface 160 may be implemented in various embodiments.
  • the input / output interface 160 may include a display 161 indicating an operation state, as shown in FIG. It may be configured to include an operation switch 162 for receiving a user's operation input, such as setting the dosage.
  • the display 161 and the operation switch 162 may be integrally implemented through a touch screen display.
  • the input / output interface 160 as shown in Figure 4, preferably further comprises a sound output means 163 for outputting a warning sound or a notification sound.
  • the main control unit 150 through the communication network (N) as shown in FIG. It is preferable that the wireless communication unit 170 is connected to any one or more of the medical institution server 300 and the guardian terminal 400 to transmit the injection history information.
  • the user terminal 200 and the guardian terminal 400 may be a personal computer, a portable terminal, or an internet of things based terminal.
  • the user terminal 200 and the guardian terminal 400 are illustrated in a shape similar to a smart phone, but the spirit of the present invention is not limited thereto, and the terminal equipped with the terminal application as described above. May be borrowed without limitation.
  • the user terminal 200 and the guardian terminal 400 may include a computer (eg, desktop, laptop, tablet, etc.), a media computing platform (eg, cable, satellite set-top box, digital video). Recorder), handheld computing device (eg, PDA, email client, etc.), any form of cellular phone, any form of other type of computing or communication platform, but the invention is not so limited.
  • the user terminal 200 may be configured to include a continuous glucose monitoring (CGM) system.
  • CGM continuous glucose monitoring
  • the communication network N serves to connect any one or more of the user terminal 200, the medical institution server 300, and the guardian terminal 400 with the wireless communication unit 170. That is, the communication network (N) is a communication network for providing a connection path so that any one or more of the user terminal 200, medical institution server 300 and the guardian terminal 400 and the wireless communication unit 170 can transmit and receive data. Means.
  • the communication network N may be a wired network such as local area networks (LANs), wide area networks (WANs), metropolitan area networks (MANs), integrated service digital networks (ISDNs), or wireless LANs, CDMA, Bluetooth, satellite communications. Although it may include a wireless network such as, but the scope of the present invention is not limited thereto.
  • the user terminal 200 is preferably configured to further include a camera 210 as shown in FIG.
  • the user terminal 200 the image of the housing of the pen-type injection device 1 or the insulin container 14 taken through the camera 210 (in particular, QR as shown in Figure 2)
  • QR as shown in Figure 2
  • the ampoule information delivered in this way may be included in the infusion history information and managed, as well as useful in the setting operation process or drug dose calculation process to be described later.
  • the universally mounted input measurement and management system of the pen-type injection device is used. It is preferable to perform the entire setup process (S10) first.
  • the setting process S10 is performed by administering the universally mounted dose measuring and management system 100 of the pen-type injection device to the housing of the pen-type injection device 1 as shown in (a) of FIG. 5.
  • the dose knob contact portion 132 is mounted in close contact with the upper side of the dose knob 12
  • the first position of the measurement slide rod 130 is measured through the measurement slide rod position sensor 140 (S11). )do.
  • the dose knob 12 is rotated to set the maximum injection volume, and then the maximum position of the measurement slide rod 130 is measured through the measurement slide rod position sensor 140 in that state (S12). )do.
  • the subsequent administration is performed.
  • the process (S20) it is possible to calculate and measure the correct dose just by measuring the position variation of the measurement slide rod 130 through the measurement slide rod position detection sensor 140.
  • the ampoule information including the dose of the drug stored in the insulin container 14, as shown in FIG. 9 may be received and provided through the ampoule information extraction process (S30) through the user terminal 200. That is, the user terminal 200 uses the camera 210 to capture images of the housing of the pen-type injection device 1 or the insulin container 14 (particularly, a QR code portion as shown in FIG. 2). Take a picture (S31). Thereafter, the image is processed (S32), and the ampoule corresponding to the photographed image among the ampoule information of various manufacturers / types of drugs / insulin container ampoules stored in the database 240 of the user terminal 200. Search for information (S33), extract the corresponding ampoule information (S34) and transfer it to the main control unit 150 through the wireless communication unit 170 using the communication network (N), more conveniently and quickly It is also possible to proceed with the setting process (S10).
  • the user terminal 200 uses the camera 210 to capture images of the housing of the pen-type injection device 1 or the insulin container 14 (particularly, a QR code portion as
  • the position of the measurement slide rod 130 is continuously measured in real time through the measurement slide rod position detection sensor 140 (S21). In this case, as shown in (b) of FIG. 5, the position of the measurement slide rod 130 continues to fluctuate even while setting the dose by adjusting the dose knob 12.
  • the drug dosage and the dosing time measured in this way is administered by the universally mounted dose measurement and management system 100 itself as the injection history information (S40), or through the communication network (N) the user terminal 200, medical institution server ( It may be delivered to any one or more of the 300 and the guardian terminal 400 may be managed by an external device (S50).

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  • Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne un système de gestion et de mesure de dosage de type à montage universel pour un dispositif d'injection de type stylo. Un système de gestion et de mesure de dosage de type à montage universel (100) pour un dispositif d'injection de type stylo est monté sur un dispositif d'injection de type stylo (1) et mesure un dosage d'un médicament, le système de gestion et de mesure comprenant : un corps principal (110) accouplé amovible à un boîtier (10) du dispositif d'injection de type stylo (1) par l'intermédiaire d'une partie de montage à encliquetage (120) ; une tige coulissante de mesure (130) qui est disposée sur le corps principal (110) et se déplace avec un mouvement vers l'avant ou vers l'arrière d'un bouton de dose (12) du dispositif d'injection de type stylo (1) en raison de la rotation du bouton de dose (12) ; un capteur de positionnement (140) de tige coulissante de mesure pour détecter la position de la tige coulissante de mesure (130) ; et une unité de commande principale pour calculer un dosage de médicament qui est défini dans le bouton de dose (12) par l'intermédiaire de changements de la position de la tige coulissante de mesure (130) qui est mesurée par le capteur de positionnement (140) de tige coulissante de mesure, et gérer et afficher des informations d'historique d'injection.
PCT/KR2017/012828 2016-12-27 2017-11-14 Système de gestion et de mesure de dosage de type à montage universel pour dispositif d'injection de type stylo Ceased WO2018124463A2 (fr)

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KR1020160180099A KR101958067B1 (ko) 2016-12-27 2016-12-27 펜형 주사장치의 범용 장착형 투입량 측정 및 관리 시스템
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US20210338939A1 (en) * 2018-09-12 2021-11-04 Becton, Dickinson And Company Universal connection device for pen injectors
WO2025200904A1 (fr) * 2024-03-29 2025-10-02 上海微创生命科技有限公司 Système d'injection de liquide médicinal et dispositif d'acquisition de dose d'injection associé

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CN114259627B (zh) * 2021-12-30 2023-12-08 杭州德柯医疗科技有限公司 介入式注射装置及介入式注射系统
KR102677092B1 (ko) * 2022-01-12 2024-06-21 주식회사 푸른소나무 약물 주입 시스템
KR102677093B1 (ko) * 2022-01-25 2024-06-21 주식회사 푸른소나무 약물 주입 시스템
WO2026014586A1 (fr) * 2024-07-10 2026-01-15 김병종 Système de mesure et de gestion du volume d'injection d'un dispositif d'injection de type stylo à l'aide d'un moteur pas à pas

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HK1199847A1 (en) * 2012-02-13 2015-07-24 Sanofi-Aventis Deutschland Gmbh A supplementary device for a manually operable injection device
JP6637038B2 (ja) * 2014-10-03 2020-01-29 ノボ・ノルデイスク・エー／エス 磁気用量センサシステムおよびエラー検出を備えたペン型薬剤注射器およびアドオンモジュール

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US20210338939A1 (en) * 2018-09-12 2021-11-04 Becton, Dickinson And Company Universal connection device for pen injectors
US12329946B2 (en) * 2018-09-12 2025-06-17 Becton, Dickinson And Company Universal connection device for pen injectors
CN112773975A (zh) * 2021-01-21 2021-05-11 常州市金坛区人民医院 一种内分泌科用注射定位装置
WO2025200904A1 (fr) * 2024-03-29 2025-10-02 上海微创生命科技有限公司 Système d'injection de liquide médicinal et dispositif d'acquisition de dose d'injection associé

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