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WO2018111997A3 - Système et procédé d'amélioration de l'apprentissage par modulation neuronale - Google Patents

Système et procédé d'amélioration de l'apprentissage par modulation neuronale Download PDF

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Publication number
WO2018111997A3
WO2018111997A3 PCT/US2017/066012 US2017066012W WO2018111997A3 WO 2018111997 A3 WO2018111997 A3 WO 2018111997A3 US 2017066012 W US2017066012 W US 2017066012W WO 2018111997 A3 WO2018111997 A3 WO 2018111997A3
Authority
WO
WIPO (PCT)
Prior art keywords
neural
learning
activity
subject
enhancing learning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2017/066012
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English (en)
Other versions
WO2018111997A2 (fr
Inventor
Eleanor V. Goodall
Roderick A. Hyde
Eric C. Leuthardt
Stephen L. Malaska
Elizabeth A. Sweeney
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elwha LLC
Original Assignee
Elwha LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/381,360 external-priority patent/US10596382B2/en
Priority claimed from US15/381,252 external-priority patent/US10695570B2/en
Priority claimed from US15/381,447 external-priority patent/US10736564B2/en
Application filed by Elwha LLC filed Critical Elwha LLC
Priority to JP2019531376A priority Critical patent/JP2020507796A/ja
Priority to CN201780086621.8A priority patent/CN110325237A/zh
Priority to EP17881096.6A priority patent/EP3554606A4/fr
Priority to KR1020197020719A priority patent/KR20190099006A/ko
Publication of WO2018111997A2 publication Critical patent/WO2018111997A2/fr
Publication of WO2018111997A3 publication Critical patent/WO2018111997A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/16Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/163Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state by tracking eye movement, gaze, or pupil change
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/375Electroencephalography [EEG] using biofeedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M21/02Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis for inducing sleep or relaxation, e.g. by direct nerve stimulation, hypnosis, analgesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0456Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0492Patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36036Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of the outer, middle or inner ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055Simultaneously evaluating both cardiovascular condition and temperature
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/16Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/168Evaluating attention deficit, hyperactivity
    • AHUMAN NECESSITIES
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6814Head
    • A61B5/6815Ear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0022Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the tactile sense, e.g. vibrations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0027Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus by the hearing sense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0055Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with electric or electro-magnetic fields
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A61M2021/0005Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus
    • A61M2021/0072Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis by the use of a particular sense, or stimulus with application of electrical currents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/08Other bio-electrical signals
    • A61M2230/10Electroencephalographic signals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Psychology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Psychiatry (AREA)
  • Social Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Developmental Disabilities (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurology (AREA)
  • Acoustics & Sound (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Educational Technology (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Rehabilitation Tools (AREA)

Abstract

L'invention concerne des systèmes et des procédés associés pour améliorer l'apprentissage par un sujet. Dans un aspect, l'apprentissage d'une activité, d'un motif sonore ou d'une tâche motrice est amélioré par l'utilisation d'une stimulation neuronale. Dans un aspect, une invite amenant le sujet à effectuer l'activité est fournie, par exemple par l'intermédiaire d'un dispositif audio, vidéo ou d'un autre dispositif de sortie, en combinaison avec des stimuli neuronaux. Dans un aspect, des stimuli neuronaux sont administrés par voie percutanée à un nerf crânien. L'administration d'invites, d'exemples et de stimuli neuronaux est commandée par des circuits de commande électriques. Selon un aspect, le système est mis en œuvre en connexion avec un dispositif informatique personnel tel qu'un téléphone intelligent ou une tablette.
PCT/US2017/066012 2016-12-16 2017-12-13 Système et procédé d'amélioration de l'apprentissage par modulation neuronale Ceased WO2018111997A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2019531376A JP2020507796A (ja) 2016-12-16 2017-12-13 神経系変調を用いた学習を強化するためのシステムおよび方法
CN201780086621.8A CN110325237A (zh) 2016-12-16 2017-12-13 用神经调制增强学习的系统和方法
EP17881096.6A EP3554606A4 (fr) 2016-12-16 2017-12-13 Système et procédé d'amélioration de l'apprentissage par modulation neuronale
KR1020197020719A KR20190099006A (ko) 2016-12-16 2017-12-13 신경 조절을 이용한 학습을 강화시키는 시스템 및 방법

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US15/381,360 2016-12-16
US15/381,447 2016-12-16
US15/381,360 US10596382B2 (en) 2016-12-16 2016-12-16 System and method for enhancing learning relating to a sound pattern
US15/381,252 US10695570B2 (en) 2016-12-16 2016-12-16 Prompting system and method for enhancing learning with neural modulation
US15/381,252 2016-12-16
US15/381,447 US10736564B2 (en) 2016-12-16 2016-12-16 System and method for enhancing learning of a motor task

Publications (2)

Publication Number Publication Date
WO2018111997A2 WO2018111997A2 (fr) 2018-06-21
WO2018111997A3 true WO2018111997A3 (fr) 2018-07-26

Family

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Application Number Title Priority Date Filing Date
PCT/US2017/066012 Ceased WO2018111997A2 (fr) 2016-12-16 2017-12-13 Système et procédé d'amélioration de l'apprentissage par modulation neuronale

Country Status (5)

Country Link
EP (1) EP3554606A4 (fr)
JP (1) JP2020507796A (fr)
KR (1) KR20190099006A (fr)
CN (1) CN110325237A (fr)
WO (1) WO2018111997A2 (fr)

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US20220168585A1 (en) * 2019-03-04 2022-06-02 The Methodist Hospital Dynamically Controlling Self-Directed Magnetic Stimulation
US11241574B2 (en) 2019-09-11 2022-02-08 Bose Corporation Systems and methods for providing and coordinating vagus nerve stimulation with audio therapy
US11235156B2 (en) 2019-09-11 2022-02-01 Bose Corporation Wearable audio device with vagus nerve stimulation
RU195919U1 (ru) * 2019-11-22 2020-02-11 Леонид Евгеньевич Селявко Тренажер-круг для групповых занятий по восстановлению и профилактической тренировке зрительной памяти методом запоминания расцветки изображений
CN111345784B (zh) * 2020-05-09 2020-08-14 中国人民解放军海军特色医学中心 基于单兵智能骨导听觉反馈技术的可穿戴防护装备
WO2021251797A1 (fr) 2020-06-12 2021-12-16 고려대학교 산학협력단 Système de télémédecine utilisant la rétroction neurologique basée sur l'intelligence artificielle et procédé de fonctionnement associé
KR102506777B1 (ko) 2020-06-12 2023-03-08 고려대학교 산학협력단 인공지능 뉴로피드백 시스템 기반 사용자 맞춤형 미주신경 자극 및 펄스 전자기장 인가 장치 및 방법
US11832065B2 (en) 2020-06-23 2023-11-28 Bose Corporation Haptic tinnitus therapeutic system
JPWO2022123706A1 (fr) * 2020-12-09 2022-06-16
WO2022266063A1 (fr) * 2021-06-15 2022-12-22 Washington University Systèmes et procédés de stimulation nerveuse vagale auriculaire transcutanée destinés à améliorer l'apprentissage moteur, la rééducation et les applications bci
TWI773436B (zh) * 2021-07-15 2022-08-01 國立成功大學 耳廓經皮神經刺激器
WO2024071994A1 (fr) * 2022-09-26 2024-04-04 주식회사 뉴라이브 Dispositif électronique de prévention et d'atténuation du mal des transports
KR20250145036A (ko) * 2023-02-03 2025-10-13 워싱톤 유니버시티 강화된 학습을 위한 경피 이개 미주 신경 자극
CN119925779B (zh) * 2025-03-26 2025-10-28 西安交通大学 一种震动刺激治疗系统

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US20080051852A1 (en) * 2006-01-21 2008-02-28 Cerbomed Gmbh Device and method for the transdermal stimulation of a nerve of the human body
WO2009045449A1 (fr) * 2007-10-01 2009-04-09 Tinnitus Otosound Products, Llc Système et méthode de thérapie adaptative de troubles médicaux combinant une détection bioélectrique et un retour d'informations biosensorielles
US20130184781A1 (en) * 2010-07-06 2013-07-18 Emad N. Eskandar Brain Stimulation for Enhancement of Learning, Motivation, and Memory
US20160279435A1 (en) * 2015-03-27 2016-09-29 Elwha LLC, a limited liability company of the State of Delaware Ear stimulation with neural feedback sensing

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KR20190099006A (ko) 2019-08-23
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JP2020507796A (ja) 2020-03-12
CN110325237A (zh) 2019-10-11
WO2018111997A2 (fr) 2018-06-21

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