[go: up one dir, main page]

WO2018178334A3 - Purification des phycobiliproteines - Google Patents

Purification des phycobiliproteines Download PDF

Info

Publication number
WO2018178334A3
WO2018178334A3 PCT/EP2018/058294 EP2018058294W WO2018178334A3 WO 2018178334 A3 WO2018178334 A3 WO 2018178334A3 EP 2018058294 W EP2018058294 W EP 2018058294W WO 2018178334 A3 WO2018178334 A3 WO 2018178334A3
Authority
WO
WIPO (PCT)
Prior art keywords
phycobiliproteins
purification
resistant
resulting
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2018/058294
Other languages
English (en)
Other versions
WO2018178334A2 (fr
Inventor
Olivier CAGNAC
Axel ATHANE
Julien DEMOL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fermentalg SA
Original Assignee
Fermentalg SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN201880022959.1A priority Critical patent/CN110461866B/zh
Priority to KR1020197029453A priority patent/KR20190141135A/ko
Priority to AU2018246351A priority patent/AU2018246351B2/en
Priority to MX2019011554A priority patent/MX2019011554A/es
Priority to CA3057780A priority patent/CA3057780A1/fr
Priority to EP18714772.3A priority patent/EP3601318A2/fr
Priority to KR1020257006244A priority patent/KR20250052382A/ko
Priority to JP2019552498A priority patent/JP7313283B2/ja
Priority to RU2019132193A priority patent/RU2781831C2/ru
Priority to IL269540A priority patent/IL269540B2/en
Priority to CN202410576648.7A priority patent/CN118440167A/zh
Priority to US16/497,510 priority patent/US12139516B2/en
Application filed by Fermentalg SA filed Critical Fermentalg SA
Priority to BR112019020420A priority patent/BR112019020420A2/pt
Publication of WO2018178334A2 publication Critical patent/WO2018178334A2/fr
Publication of WO2018178334A3 publication Critical patent/WO2018178334A3/fr
Anticipated expiration legal-status Critical
Priority to JP2023024615A priority patent/JP7685000B2/ja
Priority to AU2024201833A priority patent/AU2024201833A1/en
Priority to US18/910,453 priority patent/US20250122249A1/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/405Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from algae
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40Colouring or decolouring of foods
    • A23L5/42Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/46Addition of dyes or pigments, e.g. in combination with optical brighteners using dyes or pigments of microbial or algal origin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/145Extraction; Separation; Purification by extraction or solubilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12Unicellular algae; Culture media therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne un nouveau procédé de purification des phycobiliprotéines, en particulier résistantes aux pH acides, les phycobiliprotéines obtenues et leurs utilisations.
PCT/EP2018/058294 2017-03-30 2018-03-30 Purification des phycobiliproteines Ceased WO2018178334A2 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
CN202410576648.7A CN118440167A (zh) 2017-03-30 2018-03-30 藻胆蛋白的纯化
AU2018246351A AU2018246351B2 (en) 2017-03-30 2018-03-30 Purification of phycobiliproteins
MX2019011554A MX2019011554A (es) 2017-03-30 2018-03-30 Purificacion de ficobiliproteinas.
CA3057780A CA3057780A1 (fr) 2017-03-30 2018-03-30 Purification des phycobiliproteines
EP18714772.3A EP3601318A2 (fr) 2017-03-30 2018-03-30 Purification des phycobiliproteines
KR1020257006244A KR20250052382A (ko) 2017-03-30 2018-03-30 피코빌리프로테인의 정제
JP2019552498A JP7313283B2 (ja) 2017-03-30 2018-03-30 フィコビリタンパク質の精製
RU2019132193A RU2781831C2 (ru) 2017-03-30 2018-03-30 Очистка фикобилипротеинов
IL269540A IL269540B2 (en) 2017-03-30 2018-03-30 Purification of phycobiliproteins
CN201880022959.1A CN110461866B (zh) 2017-03-30 2018-03-30 藻胆蛋白的纯化
KR1020197029453A KR20190141135A (ko) 2017-03-30 2018-03-30 피코빌리프로테인의 정제
US16/497,510 US12139516B2 (en) 2017-03-30 2018-03-30 Purification of phycobiliproteins
BR112019020420A BR112019020420A2 (pt) 2017-03-30 2018-03-30 purificação de ficobiliproteínas
JP2023024615A JP7685000B2 (ja) 2017-03-30 2023-02-20 フィコビリタンパク質の精製
AU2024201833A AU2024201833A1 (en) 2017-03-30 2024-03-20 Purification of Phycobiliproteins
US18/910,453 US20250122249A1 (en) 2017-03-30 2024-10-09 Purification of phycobiliproteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1752674 2017-03-30
FR1752674A FR3064635B1 (fr) 2017-03-30 2017-03-30 Purification des phycobiliproteines

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US16/497,510 A-371-Of-International US12139516B2 (en) 2017-03-30 2018-03-30 Purification of phycobiliproteins
US18/910,453 Continuation US20250122249A1 (en) 2017-03-30 2024-10-09 Purification of phycobiliproteins

Publications (2)

Publication Number Publication Date
WO2018178334A2 WO2018178334A2 (fr) 2018-10-04
WO2018178334A3 true WO2018178334A3 (fr) 2018-11-22

Family

ID=59579683

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2018/058294 Ceased WO2018178334A2 (fr) 2017-03-30 2018-03-30 Purification des phycobiliproteines

Country Status (12)

Country Link
US (2) US12139516B2 (fr)
EP (1) EP3601318A2 (fr)
JP (2) JP7313283B2 (fr)
KR (2) KR20190141135A (fr)
CN (2) CN118440167A (fr)
AU (2) AU2018246351B2 (fr)
BR (1) BR112019020420A2 (fr)
CA (1) CA3057780A1 (fr)
FR (1) FR3064635B1 (fr)
IL (1) IL269540B2 (fr)
MX (1) MX2019011554A (fr)
WO (1) WO2018178334A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3064635B1 (fr) * 2017-03-30 2021-07-23 Fermentalg Purification des phycobiliproteines
FR3081880B1 (fr) 2018-05-31 2024-12-20 Fermentalg Procede de culture d'algues rouges unicellulaires (aru) sur un melange de substrats
FR3091640B1 (fr) * 2019-01-11 2021-06-11 Fermentalg Procédé de purification de phycocyanines
FR3091703B1 (fr) 2019-01-11 2021-02-12 Fermentalg Procédé d’extraction de phycocyanines
FR3092586A1 (fr) * 2019-02-08 2020-08-14 Fermentalg Procédé optimisé d’exploitation industrielle d’algues rouges unicellulaires
BE1027115B1 (fr) * 2019-03-12 2020-10-12 B Blue Nutraceuticals S A Composition liquide comprenant de la phycocyanine
JP7580801B2 (ja) * 2019-03-29 2024-11-12 国立研究開発法人科学技術振興機構 薬物送達組成物
EP3939437A1 (fr) * 2020-07-17 2022-01-19 GNT Group B.V. Composition comprenant un extrait de spiruline
KR20240083173A (ko) * 2021-08-24 2024-06-11 더 윌리엄슨 그룹 엘엘씨 산성 조성물에서 피코시아닌의 개선된 안정화
WO2023085922A1 (fr) 2021-11-15 2023-05-19 Ful Foods B.V. Procédé de production d'une composition, composition d'extrait hydrosoluble et composition d'extrait non hydrosoluble, chaque composition étant une composition à base de micro-organismes contenant des phycobiliprotéines
WO2023112407A1 (fr) * 2021-12-13 2023-06-22 Dic株式会社 Cyanidioschyzon merolae pouvant proliférer de façon hétérotrophe dans l'obscurité, et son utilisation
FR3130842B1 (fr) 2021-12-22 2025-06-27 CarbonWorks Procede de captation des phytotoxines dans un reacteur biologique
FR3147934A1 (fr) 2023-04-19 2024-10-25 Fermentalg Procede de degradation du glycogene present dans une biomasse de galdieria

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005065697A1 (fr) * 2003-12-12 2005-07-21 Florence Minard Procede de photo-stabilisation de phycobiliproteines dans un extrait aqueux, compositions contenant des phycobiliproteines stabilisees et utilisation de phycobiliproteines stabilisees
WO2016099261A1 (fr) * 2014-12-16 2016-06-23 Rijksuniversiteit Groningen Photopigments bleus naturels, procédés pour leur production et leurs utilisations en tant que colorant
WO2017050918A1 (fr) * 2015-09-25 2017-03-30 Fermentalg Composition acide comprenant une phycocyanine

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS626691A (ja) * 1985-07-02 1987-01-13 Dainippon Ink & Chem Inc 藍藻からのフイコシアニン色素a、その製造方法及びその用途
JP3256318B2 (ja) 1993-03-19 2002-02-12 学校法人桐蔭学園 藍藻含有色素の分離法
JP4048420B2 (ja) * 2002-06-26 2008-02-20 大日本インキ化学工業株式会社 フィコシアニン色素液の精製方法
RU2320195C1 (ru) 2006-05-31 2008-03-27 Владимир Кимович Мазо Способ получения белкового препарата из цианобактерий
CN101343310B (zh) * 2008-07-16 2012-01-25 广东海洋大学 一次柱层析制备高纯度藻胆蛋白的方法
CN102329381B (zh) * 2011-09-13 2013-08-21 暨南大学 同时分离高纯度的藻蓝蛋白和别藻蓝蛋白的方法与应用
CN102731645A (zh) 2012-07-17 2012-10-17 福州大学 从藻类中分离制备食用级藻蓝蛋白的方法
MX2016008084A (es) * 2013-12-18 2016-10-12 Basf Se Ficocianina estabilizada para el color azul.
FR3044679B1 (fr) 2015-12-04 2022-06-10 Fermentalg Procede de culture d'algues, particulierement d'algues rouges unicellulaires (arus), avec du lactose
JP6681065B2 (ja) * 2016-01-14 2020-04-15 学校法人明治大学 食品、食品の加熱処理方法、フィコシアニン含有物の製造方法、及び食品の製造方法
CN106190853B (zh) 2016-04-18 2019-11-26 嘉兴泽元生物制品有限责任公司 一种高产藻蓝蛋白的红藻培养方法
FR3064635B1 (fr) * 2017-03-30 2021-07-23 Fermentalg Purification des phycobiliproteines

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005065697A1 (fr) * 2003-12-12 2005-07-21 Florence Minard Procede de photo-stabilisation de phycobiliproteines dans un extrait aqueux, compositions contenant des phycobiliproteines stabilisees et utilisation de phycobiliproteines stabilisees
WO2016099261A1 (fr) * 2014-12-16 2016-06-23 Rijksuniversiteit Groningen Photopigments bleus naturels, procédés pour leur production et leurs utilisations en tant que colorant
WO2017050918A1 (fr) * 2015-09-25 2017-03-30 Fermentalg Composition acide comprenant une phycocyanine

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
D. Y. RAHMAN ET AL: "Thermostable phycocyanin from the red microalga Cyanidioschyzon merolae, a new natural blue food colorant", JOURNAL OF APPLIED PHYCOLOGY., vol. 29, no. 3, 21 November 2016 (2016-11-21), NL, pages 1233 - 1239, XP055324295, ISSN: 0921-8971, DOI: 10.1007/s10811-016-1007-0 *
EISELE L E ET AL: "Studies on C-phycocyanin from Cyanidium caldarium, a eukaryote at the extremes of habitat", BIOCHIMICA ET BIOPHYSICA ACTA. BIOENERGET, AMSTERDAM, NL, vol. 1456, no. 2-3, 10 January 2000 (2000-01-10), pages 99 - 107, XP004338930, ISSN: 0005-2728, DOI: 10.1016/S0005-2728(99)00110-3 *
O H KAO ET AL: "Physical-chemical properties of C-phycocyanin isolated from an acido-thermophilic eukaryote, Cyanidium caldarium", BIOCHEMICAL JOURNAL, vol. 147, no. 1, 1 April 1975 (1975-04-01), GB, pages 63 - 70, XP055324293, ISSN: 0264-6021, DOI: 10.1042/bj1470063 *
SCHÖNKNECHT, G. ET AL.,: "Gene Transfer fraom Bacteria and Archea Facilitated Evolution of an Extremophilic Eukaryote", SCIENCE, vol. 339, no. 6124, 7 March 2013 (2013-03-07), US, pages 1207 - 1209, XP055503810, ISSN: 0036-8075, DOI: 10.1126/science.1231689 *
SHI-GAN YAN ET AL: "Single-step chromatography for simultaneous purification of C-phycocyanin and allophycocyanin with high purity and recovery from()", JOURNAL OF APPLIED PHYCOLOGY, KLUWER ACADEMIC PUBLISHERS, DO, vol. 23, no. 1, 27 April 2010 (2010-04-27), pages 1 - 6, XP019881942, ISSN: 1573-5176, DOI: 10.1007/S10811-010-9525-7 *

Also Published As

Publication number Publication date
US20250122249A1 (en) 2025-04-17
FR3064635B1 (fr) 2021-07-23
CN110461866B (zh) 2025-03-11
US12139516B2 (en) 2024-11-12
JP2023062127A (ja) 2023-05-02
CA3057780A1 (fr) 2018-10-04
BR112019020420A2 (pt) 2020-06-09
MX2019011554A (es) 2019-11-28
US20200115423A1 (en) 2020-04-16
RU2019132193A3 (fr) 2021-11-26
CN110461866A (zh) 2019-11-15
WO2018178334A2 (fr) 2018-10-04
IL269540B2 (en) 2025-01-01
FR3064635A1 (fr) 2018-10-05
AU2018246351B2 (en) 2023-12-21
AU2018246351A1 (en) 2019-10-10
EP3601318A2 (fr) 2020-02-05
JP7685000B2 (ja) 2025-05-28
RU2019132193A (ru) 2021-04-30
CN118440167A (zh) 2024-08-06
JP2020512334A (ja) 2020-04-23
IL269540B1 (en) 2024-09-01
JP7313283B2 (ja) 2023-07-24
AU2024201833A1 (en) 2024-05-30
KR20250052382A (ko) 2025-04-18
KR20190141135A (ko) 2019-12-23
IL269540A (en) 2019-11-28

Similar Documents

Publication Publication Date Title
WO2018178334A3 (fr) Purification des phycobiliproteines
WO2017218707A3 (fr) Anticorps inhibiteurs de points de contrôle bispécifiques
WO2016161123A8 (fr) Aérogels et leurs procédés de production
WO2017077085A3 (fr) Anticorps immunomodulateurs
EP3750907A3 (fr) Compositions à base de raav et procédés pour traiter la sclérose latérale amyotrophique
GB201910389D0 (en) Novel compounds, methods for their manufacture, and uses thereof
WO2018109170A3 (fr) Anticorps il-11ra
WO2016061389A3 (fr) Anticorps anti-alpha-synucléine et leurs méthodes d'utilisation
WO2016179257A3 (fr) Anticorps anti-cd71, anticorps anti-cd71 activables, et leurs méthodes d'utilisation
WO2016149710A8 (fr) Anticorps neutralisant le vih-1 et leurs utilisations
WO2016086175A8 (fr) Anticorps anti-cd32a déficients en effecteur
WO2018101663A3 (fr) Composition pour l'élimination de tissu biologique et procédé d'élimination de tissu biologique l'utilisant
SG11202103781TA (en) Products, uses & methods
EP3235804A4 (fr) Procédé de purification de 1,5-pentanediamine et 1,5-pentanediamine
ZA201906079B (en) Novel ester compounds, method for the production thereof and use thereof
WO2016033437A3 (fr) Polyéthers, polyamines, polythioéthers, et leurs procédés de fabrication
EP3325608A4 (fr) Procédés et micro-organismes de production de 1,3-butanediol
GB2577981B (en) Methods, products & Uses relating thereto
WO2016166296A3 (fr) Anticorps humanisés anti-axl
WO2015191945A3 (fr) Formes solides de sofosbuvir
ZA201905065B (en) Novel ester compounds, method for the production thereof and use thereof
WO2016140859A3 (fr) Variants de protoxine ii et méthodes d'utilisation
WO2016108927A3 (fr) Compositions inhibitrices de nitrification et procédés de préparation de celles-ci
WO2020127145A3 (fr) Matériaux de dispositifs électroniques
GB201813648D0 (en) Methods, products & uses relating thereto

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 18714772

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: 3057780

Country of ref document: CA

Ref document number: 2019552498

Country of ref document: JP

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 20197029453

Country of ref document: KR

Kind code of ref document: A

REG Reference to national code

Ref country code: BR

Ref legal event code: B01A

Ref document number: 112019020420

Country of ref document: BR

ENP Entry into the national phase

Ref document number: 2018246351

Country of ref document: AU

Date of ref document: 20180330

Kind code of ref document: A

ENP Entry into the national phase

Ref document number: 2018714772

Country of ref document: EP

Effective date: 20191030

ENP Entry into the national phase

Ref document number: 112019020420

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20190928

WWC Wipo information: continuation of processing after refusal or withdrawal

Ref document number: 1020197029453

Country of ref document: KR

WWG Wipo information: grant in national office

Ref document number: 201880022959.1

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 1020257006244

Country of ref document: KR