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WO2017125798A1 - Dispositif de surveillance de santé et système associé - Google Patents

Dispositif de surveillance de santé et système associé Download PDF

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Publication number
WO2017125798A1
WO2017125798A1 PCT/IB2016/054405 IB2016054405W WO2017125798A1 WO 2017125798 A1 WO2017125798 A1 WO 2017125798A1 IB 2016054405 W IB2016054405 W IB 2016054405W WO 2017125798 A1 WO2017125798 A1 WO 2017125798A1
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WO
WIPO (PCT)
Prior art keywords
monitoring device
health monitoring
user
health
sensor
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Ceased
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PCT/IB2016/054405
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English (en)
Inventor
Jagannathan GOPALAKRISHNAN
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Individual
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Individual
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Publication of WO2017125798A1 publication Critical patent/WO2017125798A1/fr
Anticipated expiration legal-status Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
    • A61B5/02125—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave propagation time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02416—Measuring pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/0245—Measuring pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/332—Portable devices specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6823—Trunk, e.g., chest, back, abdomen, hip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6831—Straps, bands or harnesses

Definitions

  • the present disclosure relates to the field of medical devices. More particularly, the present disclosure relates to a health monitoring device and system relating thereto.
  • Heart Rate Pulse rate is measurement of the heart rate, or the number of times the heart beats per minute. Since the heart pushes blood through arteries, the arteries expand and contract with the flow of the blood.
  • Sp02 It stands for Peripheral capillary oxygen saturation, and is an estimation of oxygen saturation level, which refers to concentration of oxygen in blood.
  • Hemoglobin It is a major substance in red blood cells, and its level indicates the blood's ability to carry oxygen throughout the body. Hemoglobin can be used to help physician's diagnosis and monitor Anaemia (a low hemoglobin level) and Polycythemia Vera (a highhemoglobin level). Hemoglobin levels are also used to determine if a person need blood transfusion.
  • Respiration Rate It is the number of times a person takes to breath per minute. It is usually measured when a person is at rest and simply involves counting the number of breaths for one minute by counting how many times the chest rises.
  • Body Temperature It is a measure of body's ability to generate and get rid of heat. Our body temperature can be measured in many locations of our body. The aim is to instantly detect if a child or an adult is having fever and ensure precautionary measures.
  • Pedometer It provides the counts of each step thata person takes by detecting motion of the person, which is established by incorporating dedicated accelerometer MEMS transducers, signal conditioning, and data conversion.
  • Blood glucose blood sugar
  • Blood sugar is an essential measure of health, wherein blood sugar concentration or blood glucose level is the amount of glucose present in the blood of a human being.
  • Glucose is a sugar that the body uses as a source of energy. Unless a person has diabetes, one's body regulates the amount of glucose in the blood, whereas people with diabetes may need special diets and medications to control blood glucose. The challenge however is to manage Glucose levels at optimum level since high glucose or low glucose levels are symptoms of bad health. Glucose levels fluctuate at different points of time.
  • a Chinese patent CN204765600 discloses a wristwatch based health monitoring system that includes a health data acquisition module, data processing module, GPS satellite positioning module and wireless communication module, data acquisition module, GPS satellite positioning module incorporated in a wristwatch to read health data and transfer the health data to a wireless monitoring devices.
  • Another Chinese patent CN201270540 relates to health monitoring of watch mobile phone that can ready blood pressure and pulse data.
  • the watch mobile phone is provided with switch buttons and USB expansion slots to read and transfer the blood pressure and pulse data.
  • a US patent US20030231551 relates to a health indicating wristwatch that includes a module housing having a wristband and is capable of being worn on a wrist, a liquid crystal display portion disposed on a top surface of the module housing for exhibiting a digital readout, a microcontroller enclosed in the module, a solar cell charging circuit and rechargeable battery enclosed in the module connected to solar cells mounted on the module housing and exposed to light for energizing the microcontroller, a chronometer enclosed in the module, sensing means enclosed in and on the module for measuring the wearer's body functions of body temperature, pulse and blood pressure and a push-in program activating knob located on a side of the module for selecting a function for display on the liquid crystal display.
  • the numbers expressing quantities of ingredients, properties such as concentration, reaction conditions, and so forth, used to describe and claim certain embodiments of the invention are to be understood as being modified in some instances by the term "about". Accordingly, in some embodiments, the numerical parameters set forth in the written description and attached claims are approximations that can vary depending upon the desired properties sought to be obtained by a particular embodiment. In some embodiments, the numerical parameters should be construed in light of the number of reported significant digits and by applying ordinary rounding techniques. Notwithstanding that the numerical ranges and parameters setting forth the broad scope of some embodiments of the invention are approximations, the numerical values set forth in the specific examples are reported as precisely as practicable.
  • a general object of the present disclosure is to provide a non-invasive and continuous healthmonitoring device.
  • Another object of the present disclosure is to provide a health monitoring device that can be wearable,and enables continuous health monitoring.
  • Another object of the present disclosure is to provide ahealth monitoring device with health risk alert and medication advising system.
  • Another object of the present disclosure is to provide a health monitoring device that enables provision of health risk alerts to be issued along with presentation of accurate medication advise based on analysis done by the device.
  • Yet another object of the present disclosure is to provide a health monitoring device that can enable a user to send emergency alerts messages on one or more registered numbers.
  • aspects of the present disclosure relate to a multifunctional health monitoring device for monitoring and tracking various health parameters of a human body for analysing health conditions.
  • the health monitoring device performs continuous and non-invasive measuring and monitoring ofvarious health parameters, including but not limited to, human body temperature, blood glucose level, heart beat or pulse monitoring, and blood pressure (for both diastolic and systolic).
  • the health monitoring device has been configured to analyse all vital health parameters to assist and advice a user associated with the device regarding his/her overall health condition or status.
  • the proposed health monitoring device can include one or more health monitoring sensors configured to monitor one or more health parameters of a user; a microprocessor configured to receive signals from the one or more sensors, analyse the received signals, and determine an abnormal health condition; and a communication module configured to transfer any or a combination of the signals and the determined abnormal health condition.
  • the one or more health monitoring sensors can include, but are not limited to, a temperature sensor, a near infrared (NIR) and photodiode of 1550nm based blood glucose analysis sensor, an integrated sensor using NIR, LED for detecting Pulse oximetry based Heart Rate, Oxygen Saturation ie. SP02%, an electrocardiogram (ECG), and a photo-pelthysmo graph (PPG) sensors, and any combination thereof.
  • NIR near infrared
  • ECG electrocardiogram
  • PPG photo-pelthysmo graph
  • the one or more health parameters can include, but are not limited to, human body temperature, blood glucose level, heartbeat, pulse and blood pressure.
  • the proposed device can further include a display for displaying reading associated with the one or more health parameters; a tracking unit configured to provide location information of the user; and a panic button configured to enable the user to report an emergency condition.
  • thehealth monitoring device can be a wearable device that can include one or more infrared LED and photodiode sensor(s), microcontrollers, LCD display unit, a panic button, a microcontroller unit (MCU)that has a built-in GSM, Bluetooth, and Microcontroller, a SIM card or chip holder, and a power supplying unit (can be a rechargeable Lithium ion battery).
  • the health monitoring device can include a temperature sensor, a photodiode based blood glucose analysis sensor, a blood pressure sensor, and a pulse oximetry sensor.
  • the temperature sensor can be configured to sense, read, measure and monitor body temperature
  • photodiode based glucose analysis sensor can be configured to sense blood glucose level in blood of human body by conducting diagnosisbased on infrared LED and photodiode sensors.
  • Blood pressure sensor can be configured to sense, read, measure and monitor blood pressure at appropriate time based on ECG signals, bothdiastolic blood pressure and systolic blood pressure sensor, whereas pulse oximetry sensor can be configured to sense regular pulse of human body.
  • heart beat indicating sensor can be configured to sense the heart beat rate of the human at various situations by reading the rhythm of pulses.
  • the proposed device can further include a pedometer sensor that can have an in-built accelerometer which can count the number of steps a person has walked, speed of walking, and calories burnt, analysis of which can help in ensuring health fitness, and make health plans based on the readings.
  • a pedometer sensor that can have an in-built accelerometer which can count the number of steps a person has walked, speed of walking, and calories burnt, analysis of which can help in ensuring health fitness, and make health plans based on the readings.
  • health monitoring device of the present invention can further include an electrocardiogram sensor (ECG) and a photoplethysmo sensor(PPG).
  • ECG electrocardiogram sensor
  • PPG photoplethysmo sensor
  • blood pressure can be estimated based on pulse wave transit time (PWTT) by attaching the proposed device on a user's chest.
  • PWTT pulse wave transit time
  • disclosed noninvasive methods can be classified into two categories of intermittent and continuous measurement, wherein intermittent measurement can be based on cuff method thatuses auscultation and/or oscillometry, and whereas method for continuous blood pressure measurement includes Volume-clamp based, tonometry-based, and Pulse Transit Time (PTT) based methods.
  • PTT Pulse Transit Time
  • PTT or pulse wave velocity can be configured as an indirect parameter to measure blood pressure (BP) continuously and non- invasively.
  • PWV can be calculated using a ratio between height and PTT, modelling the relation between BP and PWV with a correction constant that yields accurate results for estimating systolic BP.
  • health monitoring device of the present disclosure can include atracking modulethat can be a GPS based device to locate current location of user.
  • the health monitoring device can include an alarm button that, on being pressed, can send an alarm signal to one or more preconfigured contacts.
  • location of the user can be tagged with the alarm signal.
  • Other location based services can be enabled using the tracking module in order to provide safety and security on pressingof the alarm button (which can generate a buzzer sound)for triggeringa message to registered users (as saved in the device and can also integrated with a communicating device), including but not limited to, doctors, relatives, friends, ambulance service, police.
  • the proposed device can be in the form of a wearable device that can be used as a safety device for women and children control room, etc in situation of emergency or in case of any mis-happening.
  • the proposed health monitoring device can include aSIM card holder in which a SIM card can be inserted to facilitate the health monitoring device to operate as mobile device enabled to communicate with other communicable devices at far end.
  • the health monitoring device can have Bluetooth connectivityto connect with various mobile applications or computing devices wirelessly based on authentication means to transfer data whenever needed.
  • the proposed health monitoring device can include microcontrollersthat can be programmed to receive data from various health monitoring sensors for sensing and monitoring readings of blood pressure, temperature, blood glucose level, heart beat etc and analyse them based on some algorithms. The measured values with respect to all vital health factors/parameters can be finally calculated, analysed and can be shown to the user in a user understandable format via the LCD display present on the health monitoring device.
  • the health monitoring device can be configured to provide easy and smooth integration of health monitoring device with other devices in situation of emergency to generate alertsfor generating dynamic reports and medical history of user's health condition for purpose of medical assistance or treatment to be provided.
  • the device can connect and transfer universally by any mode of communication wired or wireless, and to all systems of medical or non-medical field.
  • the health monitoring device has been configured to identify alcohol drinking habits of a driver or any person driving any motor vehicle beyond the permissible limits.
  • FIG. 1 illustrates an exemplary system overview by showing functional modules of the proposed health monitoring device in accordance with embodiments of the present disclosure.
  • FIG. 2 illustrates an implementation overview for process of blood pressure estimation in accordance with embodiments of the present disclosure.
  • FIGs. 3A to 31 illustrate exemplary circuit diagrams of a main card of a health monitoring device that includes various sensors for sensing and measuring different vital health parameters in accordance with embodiments of the present disclosure.
  • FIG. 4A illustrates an exemplary circuit diagrams of ECG unit for blood pressure monitoring in accordance with embodiments of the present disclosure.
  • FIG. 4B illustrates an exemplary circuit of 3V3 voltage regulator that can be used in accordance with an embodiment of the present disclosure.
  • FIG. 4C illustrates an exemplary circuit of Bluetooth connectivity unit that can be used in health monitoring device in accordance with an embodiment of the present disclosure.
  • aspects of the present disclosure relate to a multifunctional health monitoring device for monitoring and tracking various health parameters of a human body for analysing health conditions.
  • the health monitoring device performs continuous and non-invasive measuring and monitoring of various health parameters, including but not limited to, human body temperature, blood glucose level, heart beat or pulse monitoring, and blood pressure (for both diastolic and systolic).
  • the health monitoring device has been configured to analyse all vital health parameters to assist and advice a user associated with the device regarding his/her overall health condition or status.
  • the proposed health monitoring device can include one or more health monitoring sensors configured to monitor one or more health parameters of a user; a microprocessor configured to receive signals from the one or more sensors, analyse the received signals, and determine an abnormal health condition; and a communication module configured to transfer any or a combination of the signals and the determined abnormal health condition.
  • the one or more health monitoring sensors can include, but are not limited to, temperature sensor, a photodiode based blood glucose analysis sensor, a blood pressure sensor, a pulse oximetry sensor, an electrocardiogram (ECG), and a photoplethysmo sensor (PPG), and any combination thereof.
  • the one or more health parameters can include, but are not limited to, human body temperature, blood glucose level, heartbeat, and pulse and blood pressure.
  • the proposed device can further include a display for displaying reading associated with the one or more health parameters; a tracking unit configured to provide location information of the user; and a panic button configured to enable the user to report an emergency condition.
  • the panic button can further help connect patients with with doctors who can attend to emergencies based on the trigger issued by the button. Based on such communication of health information to doctors in real-time, the doctors can prescribe right medicine since the readings results are structured into meaningful analysis.
  • patients can also get instant health tips based on the readings from experts, which can help in a better living.
  • the health monitoring device can be a wearable device that can include one or more infrared LED and photodiode sensor(s), microcontrollers, LCD display unit, a panic button, a tracking device, a SIM card or chip holder, Bluetooth, and a power supplying unit (can be a rechargeable Lithium ion battery).
  • a wearable device can include one or more infrared LED and photodiode sensor(s), microcontrollers, LCD display unit, a panic button, a tracking device, a SIM card or chip holder, Bluetooth, and a power supplying unit (can be a rechargeable Lithium ion battery).
  • the health monitoring device can include a temperature sensor, a photodiode and NIR based blood glucose analysis sensor, a blood pressure sensor, and a pulse oximetry sensor.
  • the temperature sensor can be configured to sense, read, measure and monitor body temperature
  • NIR and photodiode based glucose analysis sensor can be configured to sense blood glucose level in blood of human body by conducting diagnosis based on infrared LED and photodiode sensors.
  • the proposed health monitoring device can be configured for continuous and non-invasive health monitoring based at least in part on blood glucose monitoring, wherein Glucose levels, in the instant invention, can be detected based on NEAR INFRARED (NIR) using IRLED and Photodiodes at higher Peak Wavelength.
  • NEAR INFRARED NEAR INFRARED
  • the proposed mechanism of detecting glucose levels can include amplification of lights using the INA122 instrumentation amplifier(s) and OPA358, which is a high speed Operational Amplifier, along with necessary resisters and capacitors.
  • 1550NM Infrared Light Emitting Diode can then be allowed to emit light, penetrating the Skin and blood, post which 1550NM INGAAS PHOTODIODE detects the light and converts into Voltage readings and captured by the Microcontroller. Post the capturing of the readings, using Regression Statistical Analysis, ADC readings can be converted into Glucose, measured in Milligrams per Deca Litre, wherein the Microcontroller controls the reading of the IRLED light at set intervals, and calculates the Glucose level.
  • IRLED Infrared Light Emitting Diode
  • data can be stored in a repository/database/memory, and can be accessed by one or more computing devices that are locally or remotely connected.
  • the time capture of Breakfast, Lunch, Dinner, Insulin and Tablets can help in identifying the impact of the events on the Glucose level, and can also help the doctor(s) to prescribe adequate dosage to bring the glucose level in control.
  • Hypoglycaemia which is a low Glucose level, can be detected, wherein one or more appropriate alerts can also be set for the user(s) and/or for doctor(s), for instance for emergency help.
  • health improvement tips based on Glucose readings can also be presented to one or more stakeholders.
  • Blood pressure sensor can be configured to sense, read, measure and monitor blood pressure at appropriate time based on algorithm of ECG signals, both diastolic blood pressure and systolic blood pressure sensor, whereas pulse oximetry sensor can be configured to sense regular pulse of human body.
  • heart beat indicating sensor can be configured to sense the heart beat rate of the human at various situations by reading the rhythm of pulses.
  • health monitoring device of the present invention can further include electrocardiogram (ECG) and photoplethysmo sensor (PPG).
  • ECG electrocardiogram
  • PPG photoplethysmo sensor
  • blood pressure can be estimated based on pulse wave transit time (PWTT) by attaching the proposed device on a user's chest.
  • disclosed non-invasive methods can be classified into two categories of intermittent and continuous measurement, wherein intermittent measurement, based on cuff method, can use auscultation and/or oscillometry, whereas method for continuous blood pressure measurement includes Volume - clamp based, tonometry-based, and Pulse Transit Time (PTT) based methods.
  • PTT or pulse wave velocity can be configured as an indirect parameter to measure blood pressure (BP) continuously and non- invasively.
  • PWV can be calculated using a ratio between height and PTT, modelling the relation between BP and PWV with a correction constant that yields accurate results for estimating systolic BP.
  • health monitoring device of the present disclosure can include a tracking module that can be a GPS based device to locate current location of user.
  • the health monitoring device can include an alarm button that, on being pressed, can send an alarm signal to one or more preconfigured contacts.
  • location of the user can be tagged with the alarm signal.
  • Other location based services can be enabled using the tracking module in order to provide safety and security on pressing of the alarm button (which can generate a buzzer sound) for triggering a message to registered users (as saved in the device and can also integrated with a communicating device), including but not limited to, doctors, relatives, friends, ambulance service, police.
  • the proposed device can be in the form of a wearable device that can be used as a safety device for women and children control room, etc in situation of emergency or in case of any mis-happening.
  • the proposed health monitoring device can include a SIM card holder in which a SIM card can be inserted to facilitate the health monitoring device to operate as mobile device enabled to communicate with other communicable devices at far end.
  • the health monitoring device can have Bluetooth connectivity to connect with various mobile applications or computing devices wirelessly based on authentication means to transfer data whenever needed.
  • the proposed health monitoring device can include microcontrollers that can be programmed to receive data from various health monitoring sensors for sensing and monitoring readings of blood pressure, temperature, blood glucose level, heart beat etc and analyse them based on some algorithms. The measured values with respect to all vital health factors/parameters can be finally calculated, analysed and can be shown to the user in a user understandable format via the LCD display present on the health monitoring device.
  • the health monitoring device can be configured to provide easy and smooth integration of health monitoring device with other devices in situation of emergency to generate alerts for generating dynamic reports and medical history of user's health condition for purpose of medical assistance or treatment to be provided.
  • the device can connect and transfer universally by any mode of communication wired or wireless, and to all systems of medical or non-medical field.
  • the health monitoring device has been configured to identify alcohol drinking habits of a driver or any person driving any motor vehicle beyond the permissible limits.
  • health monitoring device of the present disclosure can be a wearable device that can be designed to be worn on any external part of the human body for ease of use and convenience.
  • the proposed health monitoring device can interchangeably be referred to as a device hereinafter.
  • the present disclosure relates to a health monitoring device configured to monitor and report vital health parameters of a user
  • the device can include a photoplethysmo sensor (PPG) configured to sense a plurality of PPG signals of the user; an electrocardiogram (ECG) sensor configured to measure a plurality of ECG signals of the user; wherein one or more of the plurality of PPG signals and the plurality of ECG signals are processed, through a microcontroller, to compute pulse wave transit time (PWTT), based on which blood pressure (BP) of the user is determined; an a communication module configured to communicate the determined blood pressure of the user to a first computing device.
  • PPG photoplethysmo sensor
  • ECG electrocardiogram
  • PWTT pulse wave transit time
  • BP blood pressure
  • BP blood pressure
  • the peaks of the one or more of the plurality of PPG signals and the plurality of ECG signals can be used to determine the blood pressure of the user.
  • the plurality of ECG signals of the user can be measured by means of a belt worn over by the user on his/her chest, and wherein the measured plurality of ECG signals are transmitted in real-time to the health monitoring device.
  • the measured plurality of ECG signals can be transmitted in real-time to the health monitoring device by means of a Bluetooth connection.
  • the health monitoring device can be a wearable device such as any or a combination of a watch or wrist band.
  • the proposed device can further include any or a combination of a temperature sensor, a photodiode based blood glucose analysis sensor, a blood pressure sensor, and a pulse oximetry sensor.
  • the first computing device can be any or a combination of a server, cloud, a second health monitoring device, a mobile/smart phone, a laptop, a desktop PC, a tablet PC, and a PDA.
  • the blood pressure can be measured intermittently or continuously, wherein the intermittent measurement can be based on Cuff method using auscultation and oscillometry, and wherein the continuous measurement can be based on any or a combination of volume-clamp based, tonometry based measurement based, and Pulse Wave Transit Time (PWTT) based method.
  • the intermittent measurement can be based on Cuff method using auscultation and oscillometry
  • the continuous measurement can be based on any or a combination of volume-clamp based, tonometry based measurement based, and Pulse Wave Transit Time (PWTT) based method.
  • PWTT Pulse Wave Transit Time
  • the Pulse Wave Transit Time (PWTT) based method can incorporate instantaneous heart rate (HR) as a parameter while measuring the blood pressure such that the HR is added to a linear relationship between PWTT and Pulse Wave Velocity (PWV), and wherein the PWV can be calculated using ratio between height and PWTT to enable development of modelling relation between BP and PWV with a correction constant to yield accurate results for estimating systolic BP.
  • the determined BP can be any or a combination of Systolic BP and Diastolic BP.
  • the health monitoring device can include a display for displaying reading associated with the determined blood pressure; a tracking unit configured to provide location information of the user; and a panic button configured to enable the user to report an emergency condition.
  • the health monitoring device can further include a SIM card holder to enable insertion of a SIM to further enable communication with the first computing device.
  • FIG. 1 illustrates an exemplary system overview by showing functional modules of the proposed health monitoring device in accordance with embodiments of the present disclosure.
  • module diagram 100 includes a sensory data receive module 102 configured to receive sensory data/signal, at a microcontroller, from one or more health monitoring sensors that can monitor one or more health parameters of a user; a data analysis module 104 configured to analyse received data/sensory signal, and determine an abnormal health condition based on certain pre-programmed instruction; and a communication module 106 configured to transfer any or combination of the signals and the determined abnormal health condition to a third party/remote/cloud/server device.
  • the one or more health monitoring sensors can be configured to perform continuous and noninvasive measurement of the one or more health parameters.
  • the system can include a power supply module 108 to power different components of the system using battery power or solar power.
  • the one or more health monitoring sensors can be any or combination of temperature sensor, a photodiode based blood glucose analysis sensor, a blood pressure sensor, a pulse oximetry sensor, an electrocardiogram (ECG), and a photoplethysmo sensor (PPG).
  • temperature sensor a photodiode based blood glucose analysis sensor
  • blood pressure sensor a blood pressure sensor
  • pulse oximetry sensor a pulse oximetry sensor
  • ECG electrocardiogram
  • PPG photoplethysmo sensor
  • communication module 106 can include a short range wireless communication module, and long range wireless communication module, wherein short range wireless communication, for example, can include Bluetooth based communication.
  • sensory data receive module 102 can be configured to read sensory data (also referred interchangeably as sensory signal) from an electro cardio graph (ECG) module 110, and a photopelthysmograph (PPG) module 112, wherein the system can include one or more analog-to-digital (A/D) converter modules to convert sensory data of analog format into corresponding digital formalin
  • ECG module 110 can collect ECG signal(s) via a heart rate safety belt worn on chest of a user
  • PPG module 112 can collect PPG signal(s) from one finger of the user.
  • the device can be controlled through low power microcontrollers.
  • FIG. 2 illustrates an implementation overview for process of blood pressure estimation in accordance with embodiments of the present disclosure.
  • health monitoring device of the present disclosure can detect peak as shown at block 202 from ECG signals and peak of PPG as shown at block 204 from PPG signal.
  • a heart rate (HR) belt can be worn at chest to collect ECG signals, wherein based on the peaks detected from ECG signal(s) and PPG signal(s), PTT and HR can be calculated as shown at block 206.
  • the device can estimate BP as shown at block 208.
  • the health monitoring device and the heart monitoring safety belt can communicate with each other via Bluetooth. On continuous collection and transmission of ECG and PPG signals, estimation of PTT and BP can be done, wherein PTT can be calculated based on processing of ECG and/or PPG signals collected by the proposed device.
  • health monitoring device of the present invention can include electrocardiogram (ECG) and photopelthysmograph (PPG) sensors.
  • blood pressure can be estimated based on pulse wave transit time (PWTT) by attaching device on chest of a user.
  • PWTT pulse wave transit time
  • Current non-invasive methods can be classified into two categories viz intermittent measurement and continuous measurement, wherein intermittent measurement can be based on cuff method that uses auscultation and oscillometry.
  • Continuous blood pressure measurement methods can include volume-clamp based, tonometry based measurement based, and Pulse Transit Time (PTT) based methods.
  • the PTT or pulse wave velocity (PWV) can be the most useful and convenient indirect methods to measure blood pressure (BP) continuously and non-invasively.
  • HR blood pressure
  • PTT blood pressure
  • PWV blood pressure
  • heart monitoring safety belt can be worn by the patient, and ECG signals can be monitored in addition to the pulse oximetry. Systolic and Diastolic readings can be computed based on ECG and PPG signals. In an exemplary implementation, medications can be more accurate depending on real time data of one or more health monitoring sensors.
  • blood pressure can be monitoredcontinuously and without Cuff and Air Values.
  • photoplethysmo sensor(FFG) Max30102 or Max30100 can be configured to sense the Heart Rate based on Pulse Oximetry of the user to give the Heart Rate based on Wrist reading.
  • Electrocardiogram (ECG) sensor AD 8232 can be configured to measure a plurality of ECG signals based on which the user derives QRS Peak using an algorithm. Analog Signal can be converted into Digital Signal using I2C communication, wherein the readings can be transmitted to the Main terminal using the Bluetooth.
  • one or more of the plurality of PPG signals and the plurality of ECG signals can be processed, through a microcontroller, to compute pulse wave transit time (PWTT), based on which blood pressure (BP) of the user can be determined.
  • PWTT pulse wave transit time
  • BP blood pressure
  • derived readings of the past 10 Systolic and Diastolic results can be included to arrive at the new BPM readings.
  • two PPG signals, one from the Wrist, and the other from the Finger can be compared with the ECG/EKG signal.
  • the proposed device enables Blood Pressure for both Systolic as well as Diastolic to be calculated, and the output be sent to a user interface/device (configured for instance as a software) at set/periodic/configurable intervals using the GSM and Simcard.
  • the proposed health monitoring device can enable Heart Rate Monitoring using Pulse Oximetry that is derived based on readings from MAX30102/MAX30100.
  • the device can be integrated with an IRLED sensor and have an in-built Amplifier, and proximity Sensor that converts into the Heart Rate, measured in Beats per Minute, (BPM).
  • the health monitoring device can further include SP02 for measuring Oxygen Saturation in Blood, which can be calculated as a percentage using the Pulse Oximetry Max30102/Max30100 sensor. The user can be given an alert using the set norms if the SP02 is lower than expected norms.
  • the health monitoring device can further include a Temperature Sensor configured to sense body temperature (measured in degrees Centrigrade or in Fahrenheit). Any deviation in Body temperature beyond 98.6 Deg, will set trigger to the registered members.
  • the device can further include a Pedometer (such as MMA9551), which is an intelligent Motion sensor that identifies distance walked and calories burnt, wherien the device allows calculation of fitness habits and intelligently estimates the needs based on the other Health parameters like Blood Glucose, Blood Pressure etc.
  • the device can further include an Alcohol Sensor (such as TGS 822), which is a Sensor that can detect Alcohol, and is statiscally defined to arrive at the Breath Alcohol Level.
  • an Alcohol Sensor such as TGS 822
  • the legally permissible level can be compared to identify excess Alcohol level.
  • the Alcohol level can also be identified with Blood glucose, Heart Beat, Blood Pressure and other vital parameters.
  • the device can further include a Safety Tracking mechanism such as a panic Button that can be pressedin order to transmit a predefined alert by SMS, Mail to the predefined people, who will be able to track exact location using the Co-ordinates.
  • a Safety Tracking mechanism such as a panic Button that can be pressedin order to transmit a predefined alert by SMS, Mail to the predefined people, who will be able to track exact location using the Co-ordinates.
  • the device can further trigger panic to the nearest police Station, Hospitals, Ambulance and other support systems.
  • Health monitoring device can additionally include a built-in buzzer that ensures, as a safety measure, sound signals to be issued in case of any emergency.
  • the device can further include an OLED display so as to present/display all readings at set/defined/pre- configured intervals to the user.
  • data collected/gathered/calculated/measured/obtained by the instant device can be safely transferred and updated to a secured server/cloud or say to a secured Virtual Platform that can be accessed by one or more authorized users/doctors/stakeholders.
  • the access can be allowed in any computing device, including but not limited to, a personal computer, laptop, mobile phone, smart phone, tablet PC, among other like devices.
  • FIGs. 3A to 3E illustrate exemplary circuit diagrams of a main card of a health monitoring device that includes various sensors for sensing and measuring different vital health parameters in accordance with embodiments of the present disclosure.
  • the proposed health monitoring device can include a microcontroller Ul 302 that can be programmed to sense and receive data from different sensors that sense different health parameters, for example blood pressure, temperature, blood glucose level, heart beat etc. and analyse them based on pre-programmed instructions. Values measured with respect to vital health factors/parameters can be received, analysed and presented to user or remote to another remote device.
  • microcontroller Ul 302 can be configured to provide easy and smooth integration of the health monitoring device with other remote devices.
  • the microcontroller Ul can be configured to generate alerts based on present reading and historical data.
  • the microcontroller Ul 302 can be configured to enable universal data communication with any suitable device over short range wireless communication, or long range wireless communication or through wired interface.
  • the microcontroller Ul 302 can be coupled to a crystal oscillator Yl 304, for example XTAL-SMD, for intermittent measurement based on the cuff method that uses oscillometry as non-invasive method for continuous BP measurement.
  • the microcontroller 302,at different pins can receive inputs for panic from a panic signal processing circuit 306, input for switch_l through switch circuit 308, and master clean pin external reset (MCLR) through MCLR circuit 310.
  • MCLR master clean pin external reset
  • the microcontroller 302 can have other pins configured for receiving other sensory data and for providing output to different circuits or modules.
  • the microcontroller can provide a buzzer Sig to activate a buzzer coupled with the health monitoring device.
  • the health monitoring device can have an inseparable assembly U5 for temperature sensor as shown in FIG. 3B that can sense body temperature and provide sensed data to the microcontroller 302.
  • the circuit of health monitoring device can include a temperature sensor, for example TMP112, that can sense body temperature.
  • Circuit of the proposed health monitoring device can include another inseparable assembly U9 of a trans-impedance amplifier 314 (for example OPA358), and U4 amplifier 316 (for example INA122) as shown in FIG. 3C.
  • the health monitoring device can further include one or more infrared LED and photodiode sensor(s), LCD display unit, a panic button, a tracking module, a SIM card, or chip holder, a Bluetooth chip, and a power supply unit.
  • the health monitoring device can include an optical sensor 318 (for example SFH7050) as shown in FIG. 3D, an infrared LED (for example SMC1550) and a photodiode (for example G13176-003P) for blood glucose level analysis.
  • an optical sensor 318 for example SFH7050
  • an infrared LED for example SMC1550
  • a photodiode for example G13176-003P
  • the health monitoring device can also include a pedometer 320(for example MMA9555L) as shown in FIG. 3E for providing counts of each step taken by a person by detecting motion of user.
  • the steps count can be established by incorporating dedicated accelerometer MEMS transducers.
  • the health monitoring device can include a heart rate detector 322 (HR) as shown in FIG. 3F.
  • the heath monitoring device can include an oxygen concentration detector (MAX30102FFD+T )for detecting percentage of oxygen in blood (SP02), which can be further correlated with BP reading.
  • the health monitoring device can use I2C level shifter 324 (for example PCA9306DCTR) as shown in FIG.
  • the health monitoring device can include a communication module 326, for example a M66FAR01A01 chip as shown in FIG. 3H, to enable communication of the health monitoring device with mobile applications or other computing devices wirelessly to transfer data and command whenever needed.
  • the health monitoring device can be configured to send data to any remote device or server using communication module 326.
  • the health monitoring device can use Bluetooth in order to enable communication with various mobile applications.
  • the health monitoring device can also include a GPS chip to enable tracking of user.
  • the health monitoring device can include a SIM card holder 330, for example micro SIM CH03-FB, that can contain a SIM card to facilitate the health monitoring device to be operated as mobile device.
  • SIM card holder 330 for example micro SIM CH03-FB, that can contain a SIM card to facilitate the health monitoring device to be operated as mobile device.
  • FIG. 4A illustrates an exemplary circuit diagrams of ECG unit for blood pressure monitoring in accordance with embodiments of the present disclosure.
  • circuit of health monitoring device can include an ECG monitoring sensor 402 for reading electrocardiogram (ECG) and photopelthysmo graph (PPG).
  • ECG electrocardiogram
  • PPG photopelthysmo graph
  • blood pressure can be estimated based on pulse wave transit time (PWTT) only by attaching that ECG monitoring sensor on chest of a user.
  • PWTT also referred to as PTT
  • PWV pulse wave velocity
  • BP blood pressure
  • the circuit can be configured to provide ECG signals that can be collected via the heart rate safety belt worn on chest by a user.
  • the circuit can be configured to use PTT or pulse wave velocity (PWV) for convenient and indirect parameter to measure blood pressure (BP) continuously and non-invasively.
  • PTT or pulse wave velocity (PWV) for convenient and indirect parameter to measure blood pressure (BP) continuously and non-invasively.
  • FIG. 4B illustrates an exemplary circuit of 3V3 voltage regulator that can be used in accordance with an embodiment of the present disclosure.
  • the circuit of health monitoring device can include a 3 V3 voltage regulator 404 as shown in FIG. 4B to regulating voltage to different components of the health monitoring device.
  • the health monitoring device can also include a phone jack stereo that can be used to connect an earphone with device for voice assistance.
  • FIG. 4C illustrates an exemplary circuit of Bluetooth connectivity unit that can be used in health monitoring device in accordance with an embodiment of the present disclosure.
  • the device can include a Bluetooth chip 406 that can be used by the health monitoring device to communicate with HR belt and to send data to the server and other devices.
  • Circuit of the health monitoring device can include a battery charge controller (for example,MCP7833) to monitor the charging up and discharging of a battery to indicate the amount of battery life left and if recharging has to be done.
  • the health monitoring device can also include an USB connector (USB_CCN) for charging the battery present in the device.
  • USB_CCN USB connector
  • the health monitoring device can also include an alcohol sensor (TGS822) to identify alcohol drinking habits of a drivers or any person driving any motor vehicle and to warn wearer of the device if a permissible limit of alcohol is crossed.
  • the health monitoring device can further include an OLED display unit (OLED QG-2864KLBEG04) that can display measured values with respect to all vital health factors/parameters in a user understandable format.
  • a buzzer for example BUZZER-HCS0503B
  • the health monitoring device can be configured with the health monitoring device that is played on pressing of an alarm button (can generate buzzer sound). On pressing of the alarm button, buzzer sound is played and an alert message can be sent to registered users (as saved in the device and can also integrated with a communicating device) such as doctors, relatives, friends, ambulance service, police control room etc. in situation of emergency or any miss happening.
  • the health monitoring device can be in form of a wearable device that can be used as a safety device for women and children.
  • the present disclosure provides a non-invasive and continuous healthmonitoring device.
  • the present disclosure provides a health monitoring device that can be a wearable device for enabling continuous health monitoring.
  • the present disclosure provides a health monitoring device with health risk alert and medication advising system.
  • the present disclosure provides a health monitoring device with health risk alert and accurate medication advising based on the analysis done by the device. [00111] The present disclosure provides a health monitoring device that can enable a user to send emergency alerts message on one or more registered numbers.
  • the present disclosure provides a health monitoring device with alarm or panic button for use in emergency situation and triggering an alert message on the registered numbers saved in device memory.

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Abstract

La présente invention concerne un dispositif de surveillance de santé conçu pour surveiller et signaler de façon non effractive les paramètres vitaux de santé d'un utilisateur, le dispositif pouvant comprendre une DEL infrarouge proche (IR) configurée pour émettre de la lumière destinée à pénétrer dans la peau et le sang de l'utilisateur ; une photodiode conçue pour détecter la lumière et convertir cette lumière en une ou plusieurs lectures de tension ; un microcontrôleur configuré pour convertir lesdites lectures de tension en au moins une valeur de niveau de glucose sur la base d'une analyse de régression statistique ; et un module de communication conçu pour communiquer la valeur de niveau de glucose déterminée de l'utilisateur à un premier dispositif informatique.
PCT/IB2016/054405 2016-01-18 2016-07-23 Dispositif de surveillance de santé et système associé Ceased WO2017125798A1 (fr)

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WO2021048642A1 (fr) * 2019-09-10 2021-03-18 Hemant Karamchand Rohera Dispositif thérapeutique médical
LU101577B1 (en) * 2019-12-30 2021-06-30 Luxembourg Inst Science & Tech List Wearable device with sensors for health and safety monitoring
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WO2021048642A1 (fr) * 2019-09-10 2021-03-18 Hemant Karamchand Rohera Dispositif thérapeutique médical
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LU101577B1 (en) * 2019-12-30 2021-06-30 Luxembourg Inst Science & Tech List Wearable device with sensors for health and safety monitoring
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