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WO2016038560A9 - Process for the preparation of enzalutamide - Google Patents

Process for the preparation of enzalutamide Download PDF

Info

Publication number
WO2016038560A9
WO2016038560A9 PCT/IB2015/056928 IB2015056928W WO2016038560A9 WO 2016038560 A9 WO2016038560 A9 WO 2016038560A9 IB 2015056928 W IB2015056928 W IB 2015056928W WO 2016038560 A9 WO2016038560 A9 WO 2016038560A9
Authority
WO
WIPO (PCT)
Prior art keywords
enzalutamide
preparation
implementations
employed
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2015/056928
Other languages
French (fr)
Other versions
WO2016038560A1 (en
Inventor
Ghanshyam WAGH
Murali BODUPALLI
Sampat YEWALE
Shinde DHANANJAY
Mahesh Kumar GADAKAR
Vinayak Gore
Ramesh Dandala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mylan Laboratories Ltd
Original Assignee
Mylan Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mylan Laboratories Ltd filed Critical Mylan Laboratories Ltd
Publication of WO2016038560A1 publication Critical patent/WO2016038560A1/en
Publication of WO2016038560A9 publication Critical patent/WO2016038560A9/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the preparation of enzalutamide. The disclosed process may be effectively implemented on an industrial scale. In some implementations, the following reaction step is employed in the production of enzalutamide.
PCT/IB2015/056928 2014-09-12 2015-09-10 Process for the preparation of enzalutamide Ceased WO2016038560A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN4469CH2014 2014-09-12
IN4469/CHE/2014 2014-09-12

Publications (2)

Publication Number Publication Date
WO2016038560A1 WO2016038560A1 (en) 2016-03-17
WO2016038560A9 true WO2016038560A9 (en) 2016-05-12

Family

ID=54293280

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2015/056928 Ceased WO2016038560A1 (en) 2014-09-12 2015-09-10 Process for the preparation of enzalutamide

Country Status (1)

Country Link
WO (1) WO2016038560A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016051423A2 (en) 2014-10-01 2016-04-07 Laurus Labs Private Limited An improved process for the preparation of enzalutamide
CN109651256A (en) * 2018-11-20 2019-04-19 上海健康医学院 A kind of preparation method of the miscellaneous Shandong amine of the grace of formula (VIII)
US20220242829A1 (en) 2019-06-27 2022-08-04 Synthon B.V. Process for preparation of enzalutamide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds

Also Published As

Publication number Publication date
WO2016038560A1 (en) 2016-03-17

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