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WO2015051572A1 - Classe de dérivés d'amides de phénylpyrazole substitués et procédé de préparation et utilisation associés - Google Patents

Classe de dérivés d'amides de phénylpyrazole substitués et procédé de préparation et utilisation associés Download PDF

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Publication number
WO2015051572A1
WO2015051572A1 PCT/CN2013/087579 CN2013087579W WO2015051572A1 WO 2015051572 A1 WO2015051572 A1 WO 2015051572A1 CN 2013087579 W CN2013087579 W CN 2013087579W WO 2015051572 A1 WO2015051572 A1 WO 2015051572A1
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
substituted
compound
organic solvent
halogenated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2013/087579
Other languages
English (en)
Chinese (zh)
Inventor
李正名
张秀兰
马金龙
周莎
熊丽霞
李永强
王宝雷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nankai University
Original Assignee
Nankai University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nankai University filed Critical Nankai University
Publication of WO2015051572A1 publication Critical patent/WO2015051572A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention porte sur une classe de dérivés d'amides de phénylpyrazole substitués tels que représentés par la formule générale (I) ayant une activité insecticide et sur le procédé de préparation et l'utilisation associés. Selon l'invention, sur la base des composés amides de pyrazole existants, un noyau benzène substitué par un substituant nitro ou d'autres groupes est introduit en position 1 d'un noyau pyrazole, ce qui améliore ainsi la résistance pesticide des composés d'origine, réduit les coûts de production et améliore l'activité insecticide vis-à-vis de certains animaux nuisibles, les dérivés ainsi obtenus sont particulièrement très efficaces vis-à-vis des animaux nuisibles lépidoptères, tels que la chenille légionnaire orientale, Plutella xylostella, etc. ; ce sont donc des insecticides présentant une large perspective d'application.
PCT/CN2013/087579 2013-09-29 2013-11-21 Classe de dérivés d'amides de phénylpyrazole substitués et procédé de préparation et utilisation associés Ceased WO2015051572A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310456588.7A CN103467380B (zh) 2013-09-29 2013-09-29 一类取代苯基吡唑酰胺衍生物及其制备方法和应用
CN201310456588.7 2013-10-08

Publications (1)

Publication Number Publication Date
WO2015051572A1 true WO2015051572A1 (fr) 2015-04-16

Family

ID=49792461

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2013/087579 Ceased WO2015051572A1 (fr) 2013-09-29 2013-11-21 Classe de dérivés d'amides de phénylpyrazole substitués et procédé de préparation et utilisation associés

Country Status (2)

Country Link
CN (1) CN103467380B (fr)
WO (1) WO2015051572A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110041260A (zh) * 2019-05-17 2019-07-23 南开大学 一类多取代吡唑酰胺衍生物及其制备方法和用途
US10743535B2 (en) 2017-08-18 2020-08-18 H&K Solutions Llc Insecticide for flight-capable pests
CN114716408A (zh) * 2022-03-23 2022-07-08 南开大学 一类含芳香酰胺的双酰胺类衍生物及其制备方法和应用

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20221373T1 (hr) 2014-03-07 2023-01-06 Biocryst Pharmaceuticals, Inc. Supstituirani pirazoli kao inhibitori kalikreina u ljudskoj plazmi
CN105712975B (zh) * 2016-01-26 2018-10-12 西安近代化学研究所 一种含有1,2,3-三唑环的吡唑酰胺化合物和应用
CN108530407A (zh) * 2017-03-04 2018-09-14 华南农业大学 螺环酰胺类化合物的制备及其应用
CN109928928A (zh) * 2017-12-15 2019-06-25 南开大学 一类含n-苯基吡唑的双酰胺类衍生物及其制备方法和应用
CN112939866A (zh) * 2019-12-10 2021-06-11 南开大学 一类氟取代的苯基吡唑酰胺衍生物及其制备方法和应用
CN115572282B (zh) * 2021-07-05 2024-07-09 华东理工大学 含芳杂环结构的吡唑酰胺类化合物及其制备方法和应用
CN114621144A (zh) * 2022-03-23 2022-06-14 南开大学 一类氰基取代的苯基吡唑酰胺衍生物及其制备方法和用途
CN115772132B (zh) * 2022-08-05 2024-03-15 山东大学 脒/胍基修饰的真菌cyp51抑制剂衍生物及其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1713819A (zh) * 2001-09-21 2005-12-28 杜邦公司 邻氨基苯甲酰胺杀节肢动物处理
CN1972915A (zh) * 2004-04-13 2007-05-30 杜邦公司 邻氨基苯甲酰胺杀虫剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002319814A1 (en) * 2001-08-13 2003-03-03 E.I. Du Pont De Nemours And Company Substituted 1h-dihydropyrazoles, their preparation and use
CN101659655A (zh) * 2009-09-15 2010-03-03 南开大学 一类吡唑酰胺衍生物及其应用
CN101967139B (zh) * 2010-09-14 2013-06-05 中化蓝天集团有限公司 一种含一氟甲氧基吡唑的邻甲酰氨基苯甲酰胺类化合物、其合成方法及应用
CN102276580B (zh) * 2011-06-02 2013-11-06 南开大学 吡唑甲酰基硫脲衍生物与制备方法和应用

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1713819A (zh) * 2001-09-21 2005-12-28 杜邦公司 邻氨基苯甲酰胺杀节肢动物处理
CN1972915A (zh) * 2004-04-13 2007-05-30 杜邦公司 邻氨基苯甲酰胺杀虫剂

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10743535B2 (en) 2017-08-18 2020-08-18 H&K Solutions Llc Insecticide for flight-capable pests
CN110041260A (zh) * 2019-05-17 2019-07-23 南开大学 一类多取代吡唑酰胺衍生物及其制备方法和用途
CN114716408A (zh) * 2022-03-23 2022-07-08 南开大学 一类含芳香酰胺的双酰胺类衍生物及其制备方法和应用

Also Published As

Publication number Publication date
CN103467380A (zh) 2013-12-25
CN103467380B (zh) 2015-06-24

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