WO2014178197A1 - Hollow elongated body - Google Patents

Abstract

A hollow elongated body (1) that is inserted inside the body and comprises, on one end section (1ap) of the hollow elongated body (1), an expansion section (1ep) that expands in the radial direction of the hollow elongated body (1). The hollow elongated body (1) is characterized by comprising, on the expansion section (1ep), a blood clot severing member (2) that severs blood clots.

Description

Hollow long body

The present invention relates to a hollow long body, and more particularly, to a hollow long body capable of removing a relatively large thrombus.

In order to remove a thrombus in a blood vessel, a technique of sucking a thrombus using a catheter composed of a long body having a hollow portion (hollow long body) is known. For example, in Patent Document 1, a flexible elongated body having a distal end and a proximal end, including a catheter tube having a hollow portion therein, and a thrombus cutting member is provided inside the catheter tube near the distal end. A thrombus aspiration catheter is disclosed.

JP 2007-289394 A

However, for example, a thrombosis in venous blood is larger in size than a thrombus in arterial blood. Therefore, when trying to remove a thrombus using a hollow long body for an artery (catheter tube), the thrombus is hollow. There was a problem of clogging the long body.

Therefore, an object of the present invention is to provide a hollow elongated body (for example, a catheter tube) that can remove a relatively large thrombi.

The gist of the present invention is as follows.
The hollow long body of the present invention is a hollow long body that is inserted into the body, and includes an extended portion that extends in a radial direction of the hollow long body at one end of the hollow long body, The expansion portion includes a thrombus cutting member for cutting the thrombus. According to the hollow long body of the present invention, when removing a thrombus from a blood vessel (for example, a vein) through which blood containing a relatively large size of thrombus flows, the thrombus can be prevented from clogging the hollow long body. it can.

Moreover, in the hollow long body of the present invention, it is preferable that the thrombus cutting member has a larger diameter than the inner diameter of the hollow long body main body in a state where the expanded portion is expanded. According to the said structure, the effect of the hollow elongate body of this invention of preventing that the clot of a comparatively large size is blocked in a hollow elongate body can be heightened.

Furthermore, in the hollow long body of the present invention, it is preferable that the diameter of the thrombus cutting member increases as the expanded portion expands. According to the above configuration, the thrombus can be cut in both the expanded state and the unexpanded state of the expanded portion.

Furthermore, in the hollow long body of the present invention, it is preferable that the thrombus cutting member is formed in a state where the expansion portion is expanded. According to the above configuration, the thrombus cutting member can be prepared only when the operation for removing the thrombus is performed.

Furthermore, the hollow long body of the present invention preferably includes an expansion body that expands in the radial direction of the hollow long body, and the outer diameter of the expansion body is preferably larger than the inner diameter of the expansion portion. According to the above configuration, the thrombus in the blood vessel can be efficiently drawn into the expanded portion by the expansion body, thereby preventing the clot having a relatively large size from clogging the hollow long body. The effect of the long body can be further enhanced. Moreover, according to the said structure, possibility that the hollow elongate body of this invention will be damaged can be reduced.

Furthermore, the hollow long body of the present invention preferably includes an expansion body that expands in the radial direction of the hollow long body, and the outer diameter of the expansion body is preferably smaller than the inner diameter of the expansion portion. According to the above configuration, the thrombus in the blood vessel can be efficiently drawn into the expanded portion by the expansion body, thereby preventing the clot having a relatively large size from clogging the hollow long body. The effect of the long body can be further enhanced.

Furthermore, in the hollow long body of the present invention, the expansion body is configured in a spatula shape that opens radially outward from the contracted state, and is in sliding contact with the outer peripheral portion thereof in sliding contact with the inner peripheral surface of the enlarged diameter portion. An edge is preferably provided. According to the above configuration, the thrombus in the vicinity of the inner peripheral surface of the expansion portion can be efficiently cut, thereby preventing the clot having a relatively large size from being clogged by the hollow long body. The body effect can be further enhanced.

Furthermore, it is preferable that the hollow long body of the present invention is provided inside the extension part so as to be rotatable relative to the extension part. According to the said structure, it can cut | disconnect further finely by the thrombus cutting member which rotates the thrombus taken in to the expansion part.

Furthermore, it is preferable that the hollow long body of the present invention has a spring-like portion that is elastically deformable in the axial direction at the tip portion of the extension portion. According to the above configuration, the thrombus cutting member is housed inside the spring-like part until the spring-like part hits the thrombus to prevent damage to the inner wall of the blood vessel. The thrombus cutting member is exposed by contracting in the direction, and the thrombus cutting member can be rotated to finely cut the thrombus outside the expanded portion.

According to the hollow long body of the present invention, it is possible to provide a hollow long body capable of removing a relatively large thrombi.

(A) is the schematic of the catheter containing the hollow elongate body which concerns on 1st embodiment of this invention, (b) is the hollow elongate body which concerns on 1st embodiment of this invention shown to (a). The cross section of the hollow long body in a state in which the expansion part included in is not expanded (hereinafter also referred to as “non-expanded state”) along the extending direction of the hollow long body is represented by one end of the hollow long body. (C) is a state in which the extended portion of the hollow elongated body according to the first embodiment of the present invention shown in (a) is expanded (hereinafter also referred to as “expanded state”). It is a figure which expands and shows the cross section by the surface which follows the extending direction of a hollow long body of the hollow long body in FIG. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of expansion part 1epA which concerns on 1st embodiment in a non-expanded state, (b) is 1st implementation in an expanded state. It is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the expansion part 1epA which concerns on a form. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of the expansion part 1epB which concerns on 2nd embodiment in a non-expanded state, (b) is 2nd implementation in an expanded state. It is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the expansion part 1epB which concerns on a form. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of the expansion part 1epC which concerns on 3rd embodiment in a non-expanded state, (b) is 3rd implementation in an expanded state. It is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of the expansion part 1epC which concerns on a form. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of 2 A of thrombus cutting members which concern on 1st embodiment in the non-expanded state of an expansion part, (b) is an expansion part. It is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of 2 A of thrombus cutting members which concern on 1st embodiment in the expanded state. (A), (b) is a figure which shows the modification of the shape in the figure projected on the extending direction of the hollow elongate body of the thrombus cutting member which concerns on 1st embodiment shown in FIG. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of the thrombus cutting member 2B which concerns on 2nd embodiment in the non-expanded state of an expansion part, (b) is an expansion part. It is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of the thrombus cutting member 2B which concerns on 2nd embodiment in the expanded state. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of the modification 2B 'of the thrombus cutting member 2B which concerns on 2nd embodiment shown in FIG. 7 in the non-expanded state of an expansion part. (B) is a cross section of the modification 2B ′ of the thrombus cutting member 2B according to the second embodiment shown in FIG. 7 in the expanded state of the expanded portion, along the surface along the extending direction of the hollow elongated body. FIG. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of 2 C of thrombus cutting members which concern on 3rd embodiment in the non-expanded state of an expansion part, (b) is an expansion part. It is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of 2 C of thrombus cutting members which concern on 3rd embodiment in the expanded state. (A) is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of 2nd thrombus cutting member 2D which concerns on 4th embodiment in the non-expanded state of an expansion part, (b) is an expansion part. It is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of thrombus cutting member 2D which concerns on 4th embodiment in 4th expanded state. (A) is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of the thrombus cutting member 2E which concerns on 5th embodiment in the non-expanded state of an expansion part, (b) is an expansion part. It is a figure which shows the cross section by the surface in alignment with the extending direction of a hollow elongate body of the thrombus cutting member 2E which concerns on 5th embodiment in the expanded state. (A) shows the cross section by the surface along the extending direction of a hollow long body of the hollow long body which concerns on 2nd embodiment of this invention in the non-expanded state of an expansion part, One end part of a hollow long body (B) is a cross-sectional view of the hollow long body according to the second embodiment of the present invention in the expanded state of the expanded portion, taken along the surface along the extending direction of the hollow long body. It is a figure which expands and shows about the one end part of a hollow elongate body. (A) shows the cross section by the surface along the extending direction of a hollow long body of the hollow long body which concerns on 3rd embodiment of this invention in the non-expanded state of an expansion part, One end part of a hollow long body (B) is a cross-sectional view of the hollow long body according to the third embodiment of the present invention in a expanded state of the expanded portion, along a surface along the extending direction of the hollow long body. It is a figure which expands and shows about the one end part of a hollow elongate body. (A), (b) is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55A which concerns on 1st embodiment in a contracted state, (c), (d) is It is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55A which concerns on 1st embodiment in an expanded state. (A), (b) is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55B which concerns on 2nd embodiment in a contracted state, (c), (d) It is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55B which concerns on 2nd embodiment in an expanded state. (A) is a figure which shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55C which concerns on 3rd embodiment in a contracted state, (b) is 3rd embodiment in an expanded state. It is a figure which shows the cross section by the surface along the extension direction of a hollow elongate body of the balloon 55C which concerns. In the expanded state of the expanded portion, the cross section of the hollow long body according to the fourth embodiment of the present invention along the surface along the extending direction of the hollow long body is enlarged for one end and the other end of the hollow long body. It is a figure shown. (A), (b) is a figure which shows the modification of the structure which provides a thrombus cutting member relatively freely with respect to an expansion part in 4th embodiment shown in FIG. 17, respectively. (A) is the extension direction of the hollow long body of the hollow long body according to the fifth embodiment of the present invention in a state before the spring-like portion provided at the tip of the expansion portion abuts the object. FIG. 2B is an enlarged view of one end and the other end of the hollow long body, and (b) shows a spring-like portion provided at the distal end of the extension portion in contact with the object. The figure which expands and shows the cross section by the surface along the extending direction of a hollow long body of the hollow long body which concerns on 5th embodiment of this invention in a state about the one end part and other end part of a hollow long body It is. The figure which expands and shows the cross section by the surface in alignment with the extending direction of a hollow long body of the hollow long body which concerns on 6th embodiment of this invention in the expansion state of an expansion part about the one end part of a hollow long body. It is. (A)-(d) is a cross-sectional view which shows the modification of the sliding contact edge shown in FIG. 20, respectively. In the expanded state of the expanded portion, the cross section of the modification of the hollow elongated body according to the sixth embodiment of the present invention along the surface along the extending direction of the hollow elongated body is enlarged for one end of the hollow elongated body. FIG. (A)-(c) is a cross-sectional view which shows the modification of the expansion body shown in FIG. 22, respectively.

Hereinafter, embodiments of the hollow elongated body of the present invention will be described in detail with reference to the drawings.
FIG. 1A shows an outline of a catheter including a hollow long body according to the first embodiment of the present invention.
The hollow long body 1 according to the first embodiment of the present invention is a tubular long body having one end 1a and the other end 1b, and has a hollow portion 1t that opens at one end 1a and the other end 1b. The hollow long body 1 needs to be provided with an extended portion 1ep that extends in the radial direction of the hollow long body 1 at one end 1ap thereof.
In addition, the one end part 1ap of the hollow elongate body 1 refers to the part containing the one end 1a.

FIG. 1 (b) shows a hollow in a state where the extended portion provided in the hollow elongated body according to the first embodiment of the present invention shown in FIG. 1 (a) is not expanded (hereinafter also referred to as “non-expanded state”). The cross section by the surface along the extending direction of a hollow elongate body of a long body is expanded and shown about the one end part of a hollow elongate body, FIG.1 (c) shows this invention shown to Fig.1 (a). The cross section by the surface along the extending direction of a hollow long body of the hollow long body in the state (henceforth "expanded state") which the expansion part with which the hollow long body concerning a first embodiment is expanded, It expands and shows about the one end part of a hollow elongate body.
Here, as shown in FIG. 1C, the hollow long body 1 according to the first embodiment of the present invention needs to include the thrombus cutting member 2 for cutting the thrombus in the expanded portion 1ep. To do.

The hollow long body 1mp refers to a portion of the hollow long body 1 other than the extended portion 1ep.
Furthermore, cutting the thrombus refers to subdividing one thrombus into two or more thrombus portions that are physically separated.

Hereinafter, with respect to members other than the hollow long body 1, the one end and the other end thereof are determined based on the positional relationship between the one end 1a and the other end 1b of the hollow long body 1.

The hollow elongated body 1 according to the first embodiment of the present invention can be used to remove a thrombus contained in blood. Specifically, the thrombus is removed by inserting one end 1ap into a blood vessel (artery, vein) and sucking the other end 1bp. At this time, the hollow elongated body 1 may be a catheter tube inserted into a blood vessel or an introducer (sheath) that accommodates the catheter.

Thrombus in venous blood is larger in size than thrombus in arterial blood. Furthermore, thrombi in venous blood are gummy, and it is difficult to crush (subdivide) the thrombus by suction alone. Therefore, when trying to remove a thrombus using a hollow long body for an artery (catheter), there is a problem that the thrombus clogs the hollow long body.
According to the hollow long body 1 according to the first embodiment of the present invention, since the extended portion 1ep is provided at the one end 1ap, a larger-sized thrombus can be taken into the hollow portion 1t of the hollow long body 1. . Here, the blood flow of the veins is gentle compared to the arteries, and the veins can take a longer time to block the blood flow than the arteries. It is permissible to use a hollow elongate body with an extension.
And according to the hollow elongate body 1 which concerns on 1st embodiment of this invention, since the thrombus cutting member 2 is provided, the thrombus can be cut | disconnected (subdivided). Therefore, when removing a thrombus from a blood vessel (for example, a vein) through which blood containing a relatively large size of thrombus flows, it is possible to prevent the thrombus from being clogged in the hollow long body.

Conventionally, when removing a thrombus in a vein, the vein is first incised, then a deflated balloon is inserted into the vein, then the balloon is expanded, and the expanded balloon is inserted into the vein. Thus, the thrombus in the vein was removed by moving in the direction toward the incision site. Compared with this, since the method using the hollow elongated body according to the first embodiment of the present invention does not require an operation such as incision of a vein, the method is less invasive than the conventional method. can do.

Here, in the hollow long body 1 according to the first embodiment of the present invention, as shown in FIG. 1 (c), in the state in which the expanded portion 1ep is expanded, the inner diameter rm of the hollow long body main body 1mp is It is preferable to have a large diameter X in comparison.
According to this configuration, it is possible to cut a relatively large thrombus taken into the expanded portion 1ep of the hollow long body. Therefore, it is possible to enhance the effect of the hollow long body of the present invention, which prevents clogging of a relatively large sized thrombus into the hollow long body.
The inner diameter rm of the hollow long body 1mp refers to the inner diameter of the hollow portion 1t of the hollow long body 1, and the diameter X of the thrombus cutting member 2 refers to the hollow long body 1 of the thrombus cutting member 2. The maximum width in a cross section by a plane perpendicular to the extending direction.

In the hollow long body 1 shown in FIG. 1, the cross-sectional shape of the hollow portion 1t by a plane perpendicular to the extending direction of the hollow long body 1 is a circle, and the extended portion 1ep extends in the radial direction of the cross-sectional circle. However, the hollow elongated body of the present invention is not limited to this, and the cross-sectional shape may be another shape (for example, an ellipse, a rectangle, etc.), and the expanded portion 1ep has a cross-sectional area of the hollow portion 1t. May be expanded to increase

The hollow elongated body 1 shown in FIG. 1 (c) includes a thrombus cutting member 2 in both the expanded state and the unexpanded state of the expanded portion 1ep. The thrombus cutting member 2 only needs to be provided in the expanded state of the expansion portion 1ep, and the thrombus cutting member 2 may not be included in the non-expanded state of the expansion portion 1ep.

In the hollow long body 1 shown in FIG. 1, the extended portion 1 ep is provided at one end 1 ap of the hollow long body 1 over a predetermined length in the extending direction of the hollow long body 1. Here, when one end of the extended portion 1ep is 1 epa and the other end of the extended portion 1ep is 1 epb, the inner diameter re of the expanded portion 1ep is the maximum value at one end 1epa, and the one end 1epa to the other end 1epa It is the maximum value over a predetermined length up to a point A in between, and gradually decreases from the point A to the other end 1epb, and becomes the inner diameter rm of the hollow long body 1mp at the other end 1epb.
According to this configuration, when removing a thrombus from a blood vessel (for example, a vein) through which blood containing a relatively large size of thrombus flows, the effect of taking the thrombus into the hollow portion 1t of the hollow long body 1 can be enhanced. it can.

In the hollow long body 1 shown in FIG. 1, the cross-sectional shape of the extension 1ep in the extending direction of the hollow long body 1 is as described above. However, in the hollow long body of the present invention, the extension 1ep The cross-sectional shape with respect to the extending direction of the hollow long body 1 is not limited to this. For example, the inner diameter re of the expanded portion 1ep gradually decreases from one end 1epa to the other end 1epb of the expanded portion 1ep. It is good also as a shape.

(Expansion part)
Hereinafter, it describes about embodiment of the expansion part 1ep with which the hollow elongate body 1 which concerns on 1st embodiment of this invention is provided.
FIG. 2 (a) shows a cross section of the extended portion 1epA according to the first embodiment in the non-expanded state by a surface along the extending direction of the hollow elongated body, and FIG. 2 (b) shows the first in the expanded state. The cross section by the surface in alignment with the extension direction of a hollow elongate body of expansion part 1epA which concerns on embodiment is shown.
The expanded portion 1epA according to the first embodiment shown in FIG. 2 is an alloy hollow cylindrical body formed by weaving shape memory alloy wires 11 so as to intersect with each other so as to form a plurality of rhombus spaces. 12 and a flexible structure 13 covering the hollow hollow cylinder 12 made of an alloy. This cylindrical structure has the property of returning to its original shape when a force is applied in the extending direction and the radial direction of the alloy hollow cylindrical body 12 unless it is forcibly pressurized by an external force.

As shown in FIGS. 2 (a) and 2 (b), the hollow long body 1 including the expansion portion 1 epA according to the first embodiment further includes an outer cylinder member 14 that accommodates the expansion portion 1 epA of the hollow long body 1. It is preferable to provide.
And when the hollow elongate body 1 is used as a member (for example, catheter) which inserts into a blood vessel, the following effects are produced. That is, according to the expansion portion 1epA, the expansion portion 1epA located at one end 1ap (the distal end portion of the catheter) of the hollow elongated body 1 is replaced with one end 14a (the distal end of the introducer) of the outer cylinder member 14. The extension 1epA can be expanded simply by taking it out from the outside in the extending direction of the hollow elongated body 1. Therefore, according to this configuration, the expansion portion 1epA can be expanded in the radial direction of the hollow long body 1 without requiring a special operation (voluntarily).

Examples of the shape memory alloy used for the extension 1epA according to the first embodiment include Ti—Ni alloys such as Ti—Ni and Ti—Ni—Cu, Cu—Al—Mn, Cu—Al—Ni, and the like. Examples include Cu-based alloys, Fe-based alloys such as Fe-Mn-Si, Au-Cd, Ag-Cd-based alloys, and ferromagnetic shape memory alloys such as Ni-Mn-Ga and Fe-Pd. From the viewpoint of kink resistance, a Ti—Ni alloy is preferable.
Examples of the flexible material 13 used in the extended portion 1epA according to the first embodiment include polyolefins such as polyethylene and polypropylene; polystyrenes; polyamides; polyimides; polyether ether ketones; polyurethanes, polyethylene terephthalates, polybutylene terephthalates, and the like. Polyester; Fluorine resin such as polytetrafluoroethylene; Various thermoplastic elastomers such as polyolefin, polystyrene, polyamide, polyurethane, polyester, fluororubber, chlorinated polyethylene; two or more of these Combinations (polymer alloys, polymer blends, etc.) can be mentioned.

FIG. 3A shows a cross section of the extended portion 1epB according to the second embodiment in the non-expanded state by a surface along the extending direction of the hollow elongated body, and FIG. 3B shows the second in the expanded state. The cross section by the surface in alignment with the extension direction of a hollow elongate body of the expansion part 1epB which concerns on embodiment is shown. 3 (a) and 3 (b), the same reference numerals are given to the same elements as those of the expansion unit 1epA according to the first embodiment of the present invention shown in FIG. 2, and the description thereof is omitted.
The hollow elongate body 1 including the expanded portion 1epB according to the second embodiment shown in FIG. 3 further includes an outer surface member 16 that extends continuously from the one end portion 1ap. The outer surface member 16 is located on the radially outer side of the hollow long body 1, extends along the extending direction of the hollow long body 1, and forms a tubular portion 17 with the hollow long body 1. The hollow long body 1 is changed from a contracted state to an expanded state by injecting a medium (for example, air, water, etc.) into the tubular portion 17 and expands in the radial direction of the hollow long body 1. 1epB is a structure designed so that one end part 1ap of the hollow long body 1 is formed.

According to this configuration, by injecting the medium into the tubular portion 17, the extended portion 1 epB can be formed at the one end portion 1 ap of the hollow long body 1.

FIG. 4A shows a cross section of the extended portion 1epC according to the third embodiment in the non-expanded state by a surface along the extending direction of the hollow elongated body, and FIG. 4B shows the third portion in the expanded state. The cross section by the surface in alignment with the extension direction of a hollow elongate body of the expansion part 1epC which concerns on embodiment is shown.
The expanded portion 1epC according to the third embodiment shown in FIG. 4 includes a fiber hollow cylinder 19 formed by weaving the fiber member 18, and a flexible material 20 that covers the fiber hollow cylinder 19. It is a cylindrical structure including. This cylindrical structure does not have the property of returning to its original shape when a force is applied in the extending direction and the radial direction of the cylindrical body.

It is preferable that the hollow long body 1 provided with the expansion part 1epC according to the third embodiment includes a balloon 21 accommodated in the hollow part 1t of the hollow long body 1.
And when the hollow elongate body 1 is used as a catheter or an introducer (sheath), there exist the following effects. That is, according to this expansion part 1epC, the deflated balloon 21 is positioned from the other end 1b of the hollow long body 1 to one end 1ap of the hollow long body 1 (distal end of the catheter or introducer). The expansion part 1epC can be expanded by plastic deformation by inserting the balloon 21 up to the position of the expansion part 1epC and inflating the balloon 21 at the position. Therefore, according to this structure, it becomes possible to expand the expansion part 1epC to the radial direction of the hollow elongate body 1 to a desired diameter.

Examples of the fiber member 18 used in the extension portion 1epC according to the third embodiment include monofilament yarn, multifilament yarn, twisted yarn, braided string, and the like.
The flexible material 20 used for the expansion part 1epC according to the third embodiment can be the same as the flexible material 13 used for the expansion part 1epA according to the first embodiment.
As the balloon 21 used for the expansion part 1epC according to the third embodiment, a normal one in the medical field can be used.

Note that the extended portion provided in the hollow long body of the present invention is not limited to the extended portions 1epA to 1epC according to the first to third embodiments shown in FIGS. As long as the one end portion has an effect of expanding in the radial direction, the expansion portion can have any other form.

(Thrombus cutting member)
Hereinafter, embodiments of the thrombus cutting member 2 included in the hollow long body 1 according to the first embodiment of the present invention will be described.
FIG. 5 (a) shows a cross section of the thrombus cutting member 2A according to the first embodiment in the non-expanded state of the expanded portion, along the surface along the extending direction of the hollow elongated body, and FIG. The cross section by the surface in alignment with the extension direction of a hollow elongate body of 2 A of thrombus cutting members which concern on 1st embodiment in the expansion state of a part is shown.
The thrombus cutting member 2A according to the first embodiment shown in FIG. 5 is a thread-like member 31 stretched around the hollow portion 1t of the hollow long body 1. In FIG. 5, on the inner peripheral surface of the extended portion 1ep of the hollow long body 1, points P1 to P8 are defined, the first thread 31a having one end fixed to the point P1 and the other end fixed to the point P5, A second thread 31b with one end fixed at point P2 and the other end fixed at point P6, a third thread 31c with one end fixed at point P3 and the other end fixed at point P7, one end fixed at point P4, etc. A thread-like member 31 including a fourth thread 31d having an end fixed at a point P8 is provided. Here, the points P1 to P8 are on a plane perpendicular to the extending direction of the hollow long body 1, and are arranged in this order on the inner peripheral surface of the hollow long body 1 at equal intervals.

The first thread 31a to the fourth thread 31d are in a relaxed state as shown in FIG. 5A when the expanded portion 1ep is not expanded, and as shown in FIG. 5B when the expanded portion 1ep is expanded. It will be in a state of tension. In the expanded state of the expanded portion 1ep, the thread-like member 31 composed of the first thread 31a to the fourth yarn 31d has a disk shape with the inner diameter re of the expanded portion 1ep as the diameter, and the inner diameter rm of the hollow long body 1mp. The thrombus cutting member 2 has a larger diameter X compared to the above.
The first yarn 31a to the fourth yarn 31d are projected in the extending direction of the hollow long body 1 as shown in FIG. 5B in the expanded state of the expanded portion 1ep (hereinafter referred to as “projected view”). In the cross-sectional center O of the hollow long body 1.

According to this configuration, the venous blood taken from the one end 1 a of the hollow long body 1 passes through the thread-like member 31, and the thrombus in the venous blood is cut by receiving strong force from the thread-like member 31. .

In addition, the filamentous member 31 with which the hollow elongate body 1 which concerns on 1st embodiment of this invention is provided is not limited to the said structure, As long as it has the effect | action which cut | disconnects a thrombus, it can be set as what kind of structure. For example, each of the yarns forming the thread-like member 31 (in FIG. 5, the first to fourth yarns 31a to 31d) is not limited to four, and may be any number. Further, the positions at which one end and the other end of each yarn are fixed are not limited to being on one plane perpendicular to the extending direction of the hollow long body 1, and are separated with respect to the extending direction of the hollow long body 1. It may be.

As each thread | yarn which comprises the thread-like member 31, a metal wire, a synthetic fiber, a natural fiber etc. are mentioned, Especially a metal wire (especially piano wire) and a synthetic fiber are preferable from a viewpoint of sterilization and a process.
Examples of the material of each thread forming the thread-like member 31 include carbon steel.

In addition, although the thrombus cutting member 2A (thread-like member 31) according to the first embodiment shown in FIG. 5 has a radial shape centered on the point O in the projection view, the thrombus according to the embodiment of the present invention. The cutting member can have any shape without being limited thereto. For example, in the projection view, it may have a spider web shape (see FIG. 6A) or a star shape (see FIG. 6B).

FIG. 7 (a) shows a cross section of the thrombus cutting member 2B according to the second embodiment in the non-expanded state of the expanded portion by a surface along the extending direction of the hollow elongated body, and FIG. The cross section by the surface in alignment with the extending direction of a hollow elongate body of the thrombus cutting member 2B which concerns on 2nd embodiment in the expanded state of a part is shown. In FIGS. 7A and 7B, the same elements as those of the thrombus cutting member 2A according to the first embodiment of the present invention shown in FIG.
The thrombus cutting member 2B according to the second embodiment shown in FIG. 7 is a foldable member 35 stretched around the hollow portion 1t of the hollow long body 1.
The foldable member 35 is a structure including eight side portions 36 each having a first side 36 a to an eighth side 36 h and a hinge portion 37 that connects the side portions 36. In FIG. 7, points Q1 to Q8 are defined on the inner peripheral surface of the extended portion 1ep of the hollow long body 1, and one ends of the eight side portions 36 are fixed to the points Q1 to Q8, respectively. All of the other ends of the book side portions 36 are fixed to one hinge portion 37. The hinge part 37 is located at the center of the cross section by a plane perpendicular to the extending direction of the hollow long body 1.

As shown in FIG. 7A, the first side 36a to the eighth side 36h are folded around the axis of the hollow elongate body 1 in the non-expanded state of the extended portion 1ep, so that the extended portion 1ep In the expanded state, as shown in FIG. 7B, the stretched state is obtained.
In the expanded state of the extended portion 1ep, the foldable member 35 including the first side to the eighth side 36a to 36h and the hinge portion 37 has a disk shape whose diameter is the inner diameter re of the extended portion 1ep, and is hollow. The thrombus cutting member 2 has a diameter X larger than the inner diameter rm of the long body 1mp.

According to this configuration, the venous blood taken from the one end 1 a of the hollow elongated body 1 passes through the folding member 35, and the thrombus in the venous blood is cut by receiving a strong force from the folding member 35. Is done.

The folding member 35 provided in the hollow long body 1 according to the first embodiment of the present invention is not limited to the above configuration, and can have any configuration as long as it has an action of cutting a thrombus. For example, similarly to the thrombus cutting member 2A according to the first embodiment shown in FIG. 5, the number of side portions 36 (in FIG. 7, the first side to the eighth side 36a to 36h) forming the foldable member 35, The position where the side portion 36 is fixed is not limited to the above.

The material of each side portion 36 constituting the foldable member 35 is not particularly limited, and examples thereof include metals and hard resin materials.

In the thrombus cutting member 2B (foldable member 35) according to the second embodiment of the present invention shown in FIG. 7, the thrombus cutting member 2B has a radial shape centered on the point O in the projection view. However, the thrombus cutting member according to the embodiment of the present invention is not limited to this, and can have any shape as long as it does not hinder folding. For example, similarly to the thrombus cutting member 2A according to the first embodiment, the projection may have a spider web shape (see FIG. 6A) or a star shape (see FIG. 6B). It is good.

FIG. 8A shows a cross section of a surface along the extending direction of the hollow elongated body of the modified example 2B ′ of the thrombus cutting member 2B according to the second embodiment shown in FIG. FIG. 8 (b) shows a cross section of the modification 2B ′ of the thrombus cutting member 2B according to the second embodiment shown in FIG. 7 in the expanded state, along the surface along the extending direction of the hollow elongated body. Indicates. 8A and 8B, the same reference numerals are given to the same elements as those of the thrombus cutting member 2B according to the first embodiment of the present invention shown in FIG. 7, and the description thereof is omitted.
A foldable member 35 ′ shown in FIG. 8 includes a ring-shaped member 38 instead of the hinge portion 37 in the foldable member 2B shown in FIG.

In the foldable member 35 ′, another member (for example, a long body having a balloon coupled to the tip) is inserted into the ring-shaped member 38 in both the unexpanded state and the expanded state of the expansion portion 1ep. Can do.

As shown in FIGS. 5 to 8, it is preferable that the diameter X of the thrombus cutting member 2 according to the embodiment of the present invention increases as the expanded portion 1ep is expanded. In other words, the thrombus cutting member 2 is preferably expandable in the radial direction.
According to the above configuration, the thrombus can be cut in both the expanded state and the unexpanded state of the expanded portion 1ep.

FIG. 9 (a) shows a cross section of the thrombus cutting member 2C according to the third embodiment in the non-expanded state of the expanded portion, along a surface along the extending direction of the hollow elongated body, and FIG. The cross section by the surface in alignment with the extension direction of a hollow elongate body of 2 C of thrombus cutting members which concern on 3rd embodiment in the expanded state of a part is shown.
A thrombus cutting member 2 </ b> C according to the third embodiment shown in FIG. 9 is an openable / closable member 40 fixed on the inner peripheral surface of the hollow portion 1 t of the hollow long body 1. The openable / closable member 40 includes a blade 41 composed of a first blade to a fourth blade 41a to 41d. The blade 41 has a blade portion 42 having an action of cutting a thrombus, and the blade portion 42 is connected to the hollow elongated body 1. It consists of the connection part 43 fixed on the internal peripheral surface of the expansion part 1ep.
In FIG. 9, points R1 to R4 are defined on the inner peripheral surface of the extended portion 1ep of the hollow long body 1, and a first connection portion 43a fixed to the point R1 and one end thereof are connected to the first connection portion 43a. A first blade 41a composed of a first blade 41a, a second connection portion 43b fixed to the point R2, and a second blade portion 42b having one end coupled to the second connection portion 43b. The third connection part 43c fixed to the blade 41b, the point R3, and the third connection part 43c composed of the third blade part 42c having one end coupled to the third connection part 43c, and the fourth connection part fixed to the point R4. An openable / closable member 40 including a fourth blade 41d including 43d and a fourth blade portion 42d having one end coupled to the fourth connection portion 43d is provided. Here, the points R1 to R4 are on a plane perpendicular to the extending direction of the hollow long body 1, and are arranged in this order on the inner peripheral surface of the hollow long body 1 at equal intervals.

As shown in FIG. 9A, the first blade to the fourth blades 41a to 41d have a direction from one end to the other end of the blade portion 42 in the non-expanded state of the expanded portion 1ep. As shown in FIG. 9 (b), the blade portion 42 is positioned along the extending direction of the hollow elongated body 1 so as to be in the direction from the one end 1a to the other end 1b. The direction from one end to the other end of the hollow long body 1 is positioned so as to be the direction from the radially outer side to the inner side of the hollow portion 1t of the hollow long body 1.

The openable / closable member 40 including the blade 41 including the first blade to the fourth blade 41a to 41d does not function to cut the thrombus in the non-expanded state of the expansion portion 1ep, but is hollow in the expansion state of the expansion portion 1ep. The thrombus cutting member 2 has a diameter X larger than the inner diameter rm of the long body 1mp.

According to this configuration, the venous blood taken from the one end 1 a of the hollow elongated body 1 passes through the openable member 40, and the thrombus in the venous blood is severed by receiving strong force from the openable member 40. Is done.

It should be noted that the openable member 40 included in the hollow long body 1 according to the first embodiment of the present invention is not limited to the above configuration, and may have any configuration as long as it has an action of cutting a thrombus. For example, the number of each blade 41 (the first blade to the fourth blade 41a to 41d in FIG. 9) forming the openable member 40 and the position where each blade 41 is fixed are not limited to the above.

FIG. 10 (a) shows a cross section of the thrombus cutting member 2D according to the fourth embodiment in the non-expanded state of the expanded portion, along the surface along the extending direction of the hollow elongated body, and FIG. The cross section by the surface in alignment with the extending direction of a hollow elongate body of thrombus cutting member 2D which concerns on 4th embodiment in the expanded state of a part is shown.
A thrombus cutting member 2D according to the fourth embodiment shown in FIG. 10 is an upright member 45 fixed on the inner peripheral surface of the hollow portion 1t of the hollow long body 1. The stand-up member 45 includes a projection 46 composed of a first projection 46a to a fourth projection 46d. Each projection 46 has a projection main body portion 47 having an action of cutting a thrombus, and the projection main body portion 47 is formed into a hollow long shape. It consists of the coupling | bond part 48 fixed on the internal peripheral surface of the expansion part 1ep of the body 1. FIG. And in the non-expanded state of the extended portion 1ep, the protrusion main body portion 47 of each protrusion 46 is fixed by the restraining portion 49 so that the protrusion main body portion 47 is along the inner peripheral surface of the hollow portion 1t of the hollow long body 1. Has been.
In FIG. 10, points S1 to S4 are defined on the inner peripheral surface of the extended portion of the hollow elongated body, and the first coupling portion 48a fixed to the point S1 and one end coupled to the first coupling portion 48a. A first protrusion main body 47a, a first protrusion 46a consisting of a second protrusion 48a fixed to the point S2, and a second protrusion main body 47b having one end connected to the second protrusion 48b. A third coupling portion 48c fixed to the projection 46b, the point S3, and a third projection main portion 47c having one end coupled to the third coupling portion 48c, and a fourth coupling fixed to the point S4. An upright member 45 including a fourth protrusion 46d including a portion 48d and a fourth protrusion main body portion 47d having one end connected to the fourth connecting portion 48d is provided. Here, the points S1 to S4 are on a plane perpendicular to the extending direction of the hollow long body 1, and are arranged in this order on the inner peripheral surface of the hollow long body 1 at equal intervals.
Also, in FIG. 10, a first constraint in which points T1 to T8 are defined on the inner peripheral surface of the extended portion 1ep of the hollow long body 1, one end is fixed to the point T1, and the other end is fixed to the point T2. Part 49a, second constraining part 49b with one end fixed at point T3 and the other end fixed at point T4, third constraining part 49c with one end fixed at point T5 and the other end fixed at point T6, one end pointed A fourth restraining portion 49d is provided which is fixed to T7 and the other end is fixed to point T8. Here, the points T1 to T8 are on a plane perpendicular to the extending direction of the hollow elongated body 1 located on the other end 1b side of the hollow elongated body 1 with respect to the points S1 to S4.

In the non-expanded state of the extended portion 1ep, the first protrusion 46a to the fourth protrusion 46d are formed in a hollow elongated body in the direction from one end to the other end of the protrusion main body portion 47 as shown by a dotted line in FIG. Since the other end portion is restrained by the restraining portion 49 as shown by a solid line in FIG. The other end of the portion 47 is fixed so as to be positioned near the inner peripheral surface of the hollow elongated body 1. In the expanded state of the extended portion 1ep, as shown in FIG. 10 (b), the distance between one end and the other end of the restricting portion 49 (for example, between the point T1 and the point T2 in the case of the first hind foot portion 49a). Distance) increases, the restraining portion 49 breaks, and the other end of the projection main body portion 47 stands up from the position near the inner peripheral surface of the hollow long body 1 toward the radially inner side of the hollow long body 1. To do.

The stand-up member 45 including the protrusion 46 including the first protrusion 46a to the fourth protrusion 46d does not function to cut the thrombus in the non-expanded state of the expansion part 1ep, but is hollow in the expansion state of the expansion part 1ep. The thrombus cutting member 2 has a diameter X larger than the inner diameter rm of the long body 1mp.

According to this configuration, the venous blood taken from the one end 1 a of the hollow elongated body 1 passes through the standing member 45, and the thrombus in the venous blood receives a strong force from the standing member 45. Is cut off.

The material of the restraining portion 49 that forms the standing member 45 is not particularly limited, and examples thereof include metals and hard resin materials.

In addition, the standing member 45 with which the hollow elongate body 1 which concerns on 1st embodiment of this invention is provided is not limited to the said structure, As long as it has the effect | action which cut | disconnects a thrombus, it can be set as what kind of structure. . For example, like the thrombus cutting member 2A according to the first embodiment shown in FIG. 5, the number of protrusions 46 (in FIG. 10, the first protrusion to the fourth protrusions 46a to 46d) forming the upright member 45, The position where the protrusion 46 is fixed is not limited to the above.

FIG. 11 (a) shows a cross section of the thrombus cutting member 2E according to the fifth embodiment in a non-expanded state of the expanded portion, along a surface along the extending direction of the hollow elongated body, and FIG. The cross section by the surface in alignment with the extending direction of a hollow elongate body of the thrombus cutting member 2E which concerns on 5th embodiment in the expanded state of a part is shown.
The thrombus cutting member 2E according to the fifth embodiment shown in FIG. 11 is an umbrella-shaped member 50 that opens from the radially inner side to the radially outer side of the hollow elongated body 1 in the hollow portion 1t of the hollow elongated body 1. is there. The umbrella-shaped member 50 is connected to one shaft portion 51 extending in the extending direction of the hollow long body 1 and one end of the shaft portion 51, and can be expanded and contracted in a direction perpendicular to the extending direction of the hollow long body 1. Four arm portions 52 (first arm portion to fourth arm portions 52a to 52d) and the end portions that are coupled to the arm portions 52 and extend in the extending direction of the hollow elongated body 1 and are expandable in the radial direction. Part 53.

In the umbrella-shaped member 50, the arm portion 52 is moved to the hollow long body by giving displacement to the shaft portion 51 from the other end 1 b side to the one end 1 a side in the expanded state of the expansion portion 1 ep. 1 can be extended outward in the radial direction, and the end portion 53 can be expanded outward in the radial direction of the hollow elongated body 1 as the arm portion 52 extends.

Although the umbrella-shaped member 50 including the four arm portions 52 that can be expanded and contracted in the direction perpendicular to the extending direction of the hollow long body 1 does not exhibit the action of cutting the thrombus in the non-expanded state of the expanded portion 1ep, In the expanded state of the expanded portion 1ep, the thrombus cutting member 2 has a larger diameter X than the inner diameter rm of the hollow long body main body 1mp.

According to this configuration, the venous blood taken from one end 1a of the hollow elongated body 1 passes through the umbrella-shaped member 50, and the thrombus in the venous blood is removed from the umbrella-shaped member 50 (particularly, the arm portion 52). It is cut by receiving power.

In addition, the umbrella-shaped member 50 with which the hollow elongate body 1 which concerns on 1st embodiment of this invention is provided is not limited to the said structure, As long as it has the effect | action which cut | disconnects a thrombus, it can be set as what kind of structure. For example, the number of arm portions 52 (first arm portion to fourth arm portions 52a to 52d in FIG. 11) constituting the umbrella-shaped member 50 and the position where each arm portion 52 is fixed are not limited to the above.

As shown in FIGS. 9 to 11, the thrombus cutting member 2 is preferably formed in a state where the expanded portion 1ep is expanded.
According to the said structure, the clot cutting member 2 can be prepared only when performing operation which removes a thrombus.

In addition, in the umbrella-shaped member 50, the axial part 51 can also be provided so that attachment or detachment is possible. For example, the shaft portion 51 can be connected to the arm portion 52 using a screw or the like that can be attached and detached by rotating the shaft portion 51 around the axis.

In the hollow long body 1 according to the first embodiment of the present invention, the expanded portions 1epA to 1epC according to the embodiment of the present invention shown in FIGS. 2 to 4 and the embodiment of the present invention shown in FIGS. Such thrombus cutting members 2A to 2E can be used in appropriate combination.

FIG. 12 shows a hollow long body according to the second embodiment of the present invention.
FIG. 12 (a) shows a cross section of the hollow long body according to the second embodiment of the present invention in a non-expanded state of the hollow long body according to the surface along the extending direction of the hollow long body. FIG. 12B is an enlarged view of one end portion, and FIG. 12B is a cross section of the hollow long body according to the second embodiment of the present invention in the expanded state, along a surface along the extending direction of the hollow long body. Is shown enlarged for one end of the hollow elongated body. 12 (a) and 12 (b), the same elements as those of the hollow long body 1 according to the first embodiment of the present invention shown in FIG.
The hollow elongated body 1 ′ according to the second embodiment of the present invention has a plurality (three in FIG. 12) of thrombus cutting members 2 (2x, 2y, 2z), and the thrombus cutting member 2 is hollow. The long body 1 is overlaid in the extending direction.
According to this configuration, the thrombus cut (subdivided) by the thrombus cutting member 2x can be further cut by the thrombus cutting member 2y. Therefore, when removing the thrombus in venous blood, the effect of the hollow long body of the present invention that prevents the thrombus from clogging the hollow long body can be enhanced.

In the hollow elongated body 1 ′ shown in FIG. 12, the thrombus cutting member 2y is provided between the point A of the expansion portion 1ep and the other end 1epb, and the thrombus cutting member 2z is not the expansion portion 1ep. It is provided in the hollow long body main body 1mp. According to this configuration, the thrombus can be cut in stages.

In the hollow elongated body 1 ′ according to the second embodiment of the present invention, the size of the particles that can be passed by the thrombus cutting member 2y on the other end 1b side is allowed to pass by the thrombus cutting member 2x on the one end 1a side. Can be small compared to the size of the particles. That is, the thrombus cutting member 2y on the other end 1b side has finer eyes than the thrombus cutting member 2x on the one end 1a side.
According to this configuration, the thrombus can be cut (subdivided) stepwise, so that when the thrombus in venous blood is removed, the thrombus is prevented from clogging the hollow long body. The effect of the long body can be further enhanced.

FIG. 13 shows a hollow long body according to the third embodiment of the present invention.
FIG. 13A shows a cross-section of the hollow long body 1 ″ according to the third embodiment of the present invention in a non-expanded state by a surface along the extending direction of the hollow long body. FIG. 13B is an enlarged view of one end portion of the scale, and FIG. 13B shows the extension of the hollow long body of the hollow long body 1 ″ according to the third embodiment of the present invention in the expanded state. The cross section by the surface along a direction is expanded and shown about the one end part of a hollow elongate body. In FIG. 13, the hatched portion indicates only the presence of the expanded portion 1ep and the thrombus cutting member 2, and the details thereof are omitted. In FIGS. 13A and 13B, elements similar to those of the hollow long body 1 according to the first embodiment of the present invention shown in FIG.
The hollow long body 1 '' according to the third embodiment of the present invention is a balloon as an expansion body that expands in the radial direction of the hollow long body 1 outside the one end 1a in the extending direction of the hollow long body 1. 55 is further provided. The balloon 55 can be, for example, a balloon used for a Fogarty catheter for removing an arterial embolus.
According to this configuration, the deflated balloon 55 is inflated on the outer side in the extending direction of the hollow elongated body 1 than the one end 1a of the hollow elongated body 1, and the inflated balloon 55 is expanded from the one end 1a side to the other end 1b. By moving toward the side, the venous blood located on the outer side in the extending direction of the hollow long body 1 than the one end 1 a of the hollow long body 1 can be taken into the hollow portion 1 t of the hollow long body 1. Here, the taken venous blood passes through the thrombus cutting member 2, and the thrombus in the venous blood is cut (subdivided) by the thrombus cutting member 2. Therefore, if the balloon 55 is provided, thrombi in venous blood can be efficiently removed.

14 (a) and 14 (b) show a cross section of the balloon 55A as the expansion body according to the first embodiment in the contracted state along the surface along the extending direction of the hollow long body, and FIG. 14 (c), In (d), the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55A which concerns on 1st embodiment in an expanded state is shown.
The balloon 55A according to the first embodiment shown in FIG. 14 is fixed to the end of one rail 56 passing through the hollow portion 1t of the hollow long body 1 ''. Here, the hollow elongate body 1 '' shown in FIG. 14 uses the expansion portion 1epA according to the first embodiment shown in FIG. 2, and the modified example 2B ′ of the thrombus cutting member according to the second embodiment shown in FIG. (Foldable member 35 ') is used.
The method of using the balloon 55A is as follows. That is, by displacing the rail 56 in the extending direction of the hollow elongated body 1 ″, the balloon 55A is allowed to pass through the ring-shaped member 38 of the thrombus cutting member 2B ′ (FIG. 14A), and the balloon 55A is moved to the other. The balloon 55A is displaced from the end 1b side toward the one end 1a side so that the balloon 55A is positioned on the outer side in the extending direction of the hollow elongated body 1 with respect to the one end 1a of the hollow elongated body 1 (FIG. 14B). At that position, the balloon 55A is inflated, the balloon 55A is displaced from the one end 1a side toward the other end 1b side (FIG. 14C), and the balloon 55A is pressed against the one end 1a of the hollow elongated body 1 (see FIG. 14 (d)).
According to this structure, the effect that the thrombus in venous blood can be removed efficiently can be acquired.

Here, as shown in FIG. 14, one end 1 a of the hollow long body 1 ″ preferably has a tapered shape that extends from the radially inner side to the outer side of the hollow long body.
According to this configuration, when the balloon 55A is pressed against the one end 1a, the balloon 55 can easily bite into the expanded portion 1ep. Therefore, the effect that the thrombi in venous blood can be efficiently removed can be enhanced.

15 (a) and 15 (b) show a cross section of the balloon 55B as the expansion body according to the second embodiment in the contracted state along a surface along the extending direction of the hollow long body, and FIG. (D) shows the cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55B which concerns on 2nd embodiment in an expanded state.
The balloon 55B according to the second embodiment is fixed to the ends of four rails 56 (56a to 56d, only 56a and 56c are shown in FIG. 15) passing through the hollow portion 1t of the hollow long body 1 ''. It is a thing. Here, the hollow elongate body 1 '' shown in FIG. 15 uses the expanded portion 1epA according to the first embodiment shown in FIG. 2, and the thrombus cutting member 2C (opening / closing member) according to the third embodiment shown in FIG. 40).
The method of using the balloon 55B is the same as that of the balloon 55A shown in FIG.

Here, in the hollow long body 1 '' according to the third embodiment of the present invention, as shown in FIGS. 14 and 15, the outer diameter Rb of the balloon 55 (55A, 55B) in the inflated state is expanded. It is preferable that it is larger than the inner diameter re of the expanded portion 1ep in the above state.
According to this configuration, when the inflated balloon 55 is moved from the one end 1a side toward the other end 1b side, the balloon 55 enters the hollow portion 1t in the expansion portion 1ep of the hollow long body 1 ''. The contact with the thrombus cutting member 2 can be prevented. Therefore, possibility that the hollow elongate body of this invention will be damaged can be reduced.

FIG. 16 (a) shows a cross section of the balloon 55C as the expansion body according to the third embodiment in the contracted state by a surface along the extending direction of the hollow elongated body, and FIG. 16 (b) shows in the expanded state. The cross section by the surface in alignment with the extension direction of a hollow elongate body of the balloon 55C which concerns on 3rd embodiment is shown.
The balloon 55C according to the third embodiment has a stopper 60 that protrudes in the radial direction of the balloon 55C on the outer surface of the balloon 55C.
According to this configuration, the outer diameter (not shown) of the balloon 55C main body not including the stopper in the inflated state is smaller than the inner diameter re of the expanded portion 1ep in the expanded state, but the outer diameter of the balloon 55C in the expanded state. The diameter Rb is larger than the inner diameter re of the expanded portion 1ep in the expanded state. Therefore, it is possible to obtain an effect of reducing the possibility that the hollow long body of the present invention is damaged.

FIG. 17 shows a hollow long body according to the fourth embodiment of the present invention.
FIG. 17 shows a cross-section of the hollow long body 1 ′ ″ according to the fourth embodiment of the present invention in the expanded state by a surface along the extending direction of the hollow long body. One end and the other end are shown enlarged. In FIG. 17, elements similar to those of the hollow long body 1 according to the first embodiment of the present invention shown in FIG.
In the hollow elongated body 1 ′ ″ according to the fourth embodiment of the present invention, the thrombus cutting member 2 is provided on the inner side of the expanded portion 1ep so as to be rotatable relative to the expanded portion 1ep. In the case shown in the figure, the thrombus cutting member 2 is formed in a form having a radial net portion intersecting at the center of the cross section of the hollow elongated body 1 ′ ″, and its outer peripheral edge portion is fixed to the inner peripheral surface of the expansion portion 1ep. Thus, the thrombus cutting member 2 can rotate about the center of the mesh portion as an axis. A distal end of an operation shaft 70 for rotation operation made of a flexible wire material capable of transmitting rotational power, such as a metal wire, is fixed to the axis of the thrombus cutting member 2. The operation shaft 70 is disposed through the hollow portion 1t, and its end portion projects outward from the other end 1b of the hollow long body 1 ′ ″.
According to this configuration, the thrombus cutting member 2 can be rotated inside the expansion portion 1ep by rotating the end portion of the operation shaft 70 manually or using a rotary drive device or the like. And the thrombus in the venous blood taken into the inside of the expansion part 1ep from the one end 1a of the hollow long body 1 ′ ″ can be further finely cut by the rotating thrombus cutting member 2.

In the hollow long body 1 ′ ″ according to the fourth embodiment of the present invention, the expansion portions 1epA to 1epC shown in FIGS. 2 to 4 are appropriately used as the expansion portion 1ep on which the thrombus cutting member 2 is provided so as to be relatively rotatable. be able to.

Moreover, in the hollow long body 1 ′ ″ according to the fourth embodiment of the present invention, the thrombus cutting member 2 provided in the expanded portion 1ep so as to be relatively rotatable with respect to the expanded portion 1ep is of the above-described form. The present invention can be used in various forms.

For example, the thrombus cutting member 2 provided inside the expansion portion 1ep so as to be rotatable relative to the expansion portion 1ep is similar to the thrombus cutting member 2E, that is, the umbrella-shaped member 50 according to the fifth embodiment shown in FIG. It can also have. In this case, the end portion 53 is configured to be relatively rotatable with respect to the expansion portion 1ep, so that the umbrella-shaped member 50 (thrombus cutting member 2E) is expanded inside the expansion portion 1ep in the expansion state of the expansion portion 1ep. It can be set as the structure relatively rotatable with respect to. In this case, the shaft portion 51 is configured to function as an operation shaft for rotating operation.

Further, the configuration in which the thrombus cutting member 2 is provided on the inside of the expansion portion 1ep so as to be relatively rotatable with respect to the expansion portion 1ep can be configured as shown in FIGS. 18 (a) and 18 (b).
FIGS. 18A and 18B show modifications of the configuration in which the thrombus cutting member 2 is provided to be relatively rotatable with respect to the expanded portion 1ep in the fourth embodiment shown in FIG. In FIG. 18, the same elements as those of the hollow elongated body 1 ′ ″ according to the fourth embodiment of the present invention shown in FIG.

In the modification shown in FIG. 18 (a), the hollow long body 1 ′ ″ is expanded outside the one end 1a in the extending direction of the hollow long body 1 in the radial direction of the hollow long body 1. A balloon 55 as a body is further provided. The thrombus cutting member 2 is provided on the surface of the balloon 55 facing the expansion portion 1ep. In the case shown in the figure, the thrombus cutting member 2 is constituted by a plate-like cutter blade 71 having a sharp tip, and is fixed to the balloon 55 at the root portion thereof. As the balloon 55, for example, the balloon 55A according to the first embodiment shown in FIGS. 14 to 16, the balloon 55B according to the second embodiment, or the balloon 55C according to the third embodiment can be used. Further, the rail 56 is configured to function as an operation shaft for rotating operation.
According to this configuration, the inflated balloon 55 removes the venous blood thrombus on the outer side in the extending direction of the hollow long body 1 ″ ″ from the one end 1a of the hollow long body 1 ′ ″. The cutter blade 71 (thrombus cutting member 2) can be rotated inside the expansion portion 1ep together with the balloon 55 by being able to be taken in and rotating the end portion of the rail 56 manually or using a rotary drive device or the like. Thus, the thrombus taken into the expanded portion 1ep can be further finely cut by the cutter blade 71 that rotates. At this time, since the balloon 55 is pressed against the one end 1a of the hollow long body 1 ′ ″ and the expanded portion 1ep is closed, the thrombus taken into the expanded portion 1ep is sealed in the expanded portion 1ep. Can be cut in a state. Therefore, the thrombus finely cut by the rotating cutter blade 71 can be prevented from scattering to the distal side.

In the modification shown in FIG. 18 (a), the thrombus cutting member 2 is provided on the surface of the balloon 55 facing the expansion portion 1ep (proximal side). However, in the modification shown in FIG. As described above, the thrombus cutting member 2 may be provided on the rail 56 to which the balloon 55 is fixed. Also in this case, the thrombus cutting member 2 can be configured as a plate-like cutter blade 71 having a sharp tip and fixed to the rail 56 at the root portion. The cutter blade 71 is preferably fixed to the rail 56 so that the balloon 55 is positioned inside the extended portion 1ep when the balloon 55 is pressed against the one end 1a of the hollow long body 1 "". Also with this configuration, the same effect as that shown in FIG. 18A can be obtained by rotating the cutter blade 71 (thrombus cutting member 2) together with the rail 56 inside the extended portion 1ep.

In the modification shown in FIGS. 18A and 18B, the thrombus cutting member 2 is configured as a plate-like cutter blade 71 having a sharp tip, but rotates with the balloon 55 or the rail 56 to cut the thrombus. If possible, it can be of other shapes.

FIG. 19 shows a hollow long body according to the fifth embodiment of the present invention.
FIG. 19A shows a hollow long body 1 ″ ″ according to the fifth embodiment of the present invention in a state before the spring-like portion provided at the tip of the extension portion abuts against the object. The cross section by the surface along the extending direction of a long body is expanded and shown about the one end part and other end part of a hollow elongate body, and the spring-like part provided in the front-end | tip of an expansion part is shown in FIG.19 (b). A cross-section of the hollow long body 1 '''' according to the fifth embodiment of the present invention in a state of being in contact with the object along a surface along the extending direction of the hollow long body is shown as one end of the hollow long body. The enlarged portion and the other end portion are shown. 19, the same code | symbol is attached | subjected to the element similar to the hollow elongate body 1 which concerns on 1st embodiment of this invention shown in FIG. 1, and the description is abbreviate | omitted.
The hollow long body 1 '''' according to the fifth embodiment of the present invention has a spring-like portion 72 at the tip portion of the expansion portion 1ep. For example, the spring-like portion 72 may have a configuration formed by interweaving metal wires 73 so as to form a plurality of rhombus spaces. The spring-like portion 72 can be expanded in the radial direction together with the extended portion 1ep, and the tip thereof is elastically deformed in the axial direction by being pushed toward the extended portion 1ep side (proximal side). The direction length can be reduced.

In addition, the spring-like part provided at the tip of the extension part 1ep is not limited to the above-described configuration. For example, a coil-like form can be used as long as it can be expanded together with the extension part 1ep in the radial direction and elastically deformed in the axial direction. Various forms can be adopted.

In the hollow elongate body 1 '''' according to the fifth embodiment of the present invention, the thrombus cutting member 2 is positioned relative to the expanded portion 1ep and the spring-shaped portion 72 inside the spring-shaped portion 72 of the expanded portion 1ep. It is provided rotatably. In the illustrated case, the thrombus cutting member 2 is configured as a plate-like cutter blade 74. The cutter blade 74 has an elongated plate shape extending in the axial direction and has a shape bent at the intermediate portion in the longitudinal direction. The cutter shaft 74 is rotated along the operation shaft 70 at both ends in the longitudinal direction. 70 is fixed to the outer peripheral surface. In the case shown in the figure, the pair of thrombus cutting members 2 are provided at symmetrical positions with the operation shaft 70 interposed therebetween, but a configuration in which only one thrombus cutting member 2 is provided or two or more thrombus cutting members 2 are provided. It can also be configured. The operation shaft 70 can be the same as that shown in FIG. 17 and is made of a wire material that can transmit rotational power, such as a metal wire, and has a hollow end portion 1 ′ ″. It protrudes outside from the other end 1b of '.
According to this configuration, until the hollow elongated body 1 ″ ″ is inserted into the blood vessel and the spring-like portion 72 provided at the distal end portion of the expansion portion 1ep hits the object, that is, the thrombus, FIG. As shown, the cutter blade 74 is housed inside the spring-like portion 72 of the extension 1ep, and damage to the inner wall of the blood vessel due to the cutter blade 74 touching is prevented.
On the other hand, as shown in FIG. 19 (b), when the hollow elongated body 1 '''' is further inserted into the blood vessel and the spring-like portion 72 provided at the distal end portion of the expanded portion 1ep hits the object, that is, the thrombus, As shown in FIG. 19B, the spring-like portion 72 contracts in the axial direction, and the cutter blade 74 is exposed to the outside of the spring-like portion 72 and comes into contact with the thrombus. In this state, the distal end portion of the operation shaft 70 is rotated manually or using a rotary drive device or the like, so that the thrombus outside the expanded portion 1ep is finely cut by the rotating cutter blade 74, and the expanded portion 1ep has a hollow length. It can be taken into the scale 1 ''''.

Also in the hollow long body 1 '' '' '' according to the fifth embodiment of the present invention, the configuration shown in FIGS. 2 to 4 can be appropriately used as the configuration for expanding the expansion portion 1ep.

FIG. 20 shows a hollow long body according to the sixth embodiment of the present invention.
In FIG. 20, the cross section by the surface in alignment with the extension direction of a hollow long body of the hollow long body which concerns on 6th embodiment of this invention in the expansion state of an expansion part is expanded about the one end part of a hollow long body FIGS. 21A to 21D are cross-sectional views of modifications of the sliding contact edge shown in FIG. 20 and 21, elements similar to those of the hollow elongated body according to the above-described embodiment are denoted by the same reference numerals, and description thereof is omitted.
The hollow long body 1 ′ ″ ″ according to the sixth embodiment of the present invention has a spatula member 82 as an expansion body. The spatula member 82 is fixed to the tip of the rail 56, opened from the contracted state folded along the rail 56 toward the radially outer side, and is a circular shape perpendicular to the axial direction of the rail portion 56. It is configured to be deformable into a spatula-like expanded diameter state. The outer diameter dimension, that is, the outer diameter Rs, of the spatula member 82 in the diameter-expanded state is made smaller than the inner diameter re of the expanded portion 1ep, and the outer peripheral portion of the spatula member 82 is slidable in contact with the inner peripheral surface of the expanded diameter portion 1ep. A contact edge 83 is formed.
On the other hand, in the hollow elongated body 1 ′ ″ ″ according to the sixth embodiment of the present invention, the expanded portion 1ep can be configured to have the stent portion 80 at the distal end portion. This stent part 80 can be made into the structure formed by cross | intersecting and interweaving the metal wires 81 so that a some rhombus space may be formed, for example. The stent portion 80 can be expanded in the radial direction together with the expanded portion 1ep.
In the hollow elongate body 1 ′ ″ ″ according to the sixth embodiment of the present invention having such a configuration, the spatula member 82 in the contracted state is more extended than the one end 1a of the hollow elongate body 1. By moving the spatula member 82 that is opened in a circular spatula shape on the outer side in the present direction and opened and expanded in diameter from the one end 1a side (distal side) toward the other end 1b side (proximal side), The thrombus located on the outer side in the extending direction of the hollow long body 1 than the one end 1 a of the hollow long body 1 can be taken into the hollow portion 1 t of the hollow long body 1. Further, by expanding the stent portion 80 in the blood vessel, the thrombus adhering to the inner wall of the blood vessel is pushed out from the rhombus space of the stent portion 80 toward the inside of the expanded portion 1ep, but the spatula member 82 is hollow in the stent portion 80. A spatula member that reaches the inside of the stent portion 80 from the outside in the extending direction from one end 1a of the long body 1 and moves inside the stent portion 80 to push the thrombus pushed out from the rhombus space toward the inside of the expanded portion 1ep. It can cut | disconnect with the sliding contact edge 83 of 82, and can take in in the hollow elongate body 1. FIG. The thrombus thus taken up is cut (subdivided) by the thrombus cutting member 2.
Therefore, by providing the spatula member 82, the thrombus can be removed more efficiently.

The spatula member 82 shown in FIG. 20 can be configured as shown in FIGS. 21 (a) to 21 (d), for example.
For example, as shown in FIG. 21A, the spatula member 82 is provided with a protrusion 84 having a wedge-shaped cross section that protrudes from the distal side toward the proximal side on the sliding contact edge 83 provided on the outer peripheral portion thereof. Can be configured. In this case, the sliding contact edge 83 having the wedge-shaped protrusion 84 moves from the one end 1a side (distal side) to the other end 1b side (proximal side) along the inner peripheral surface of the stent portion 80, whereby the stent portion The thrombus pushed out from the 80 rhombus space toward the inside of the extended portion 1ep can be easily cut by the sharp blade at the tip of the wedge-shaped projection 84. Thereby, thrombus can be removed more efficiently.
Moreover, as shown in FIG.21 (b), the spatula member 82 can also be set as the structure by which the brush part 85 was provided in the sliding contact edge 83 provided in the outer peripheral part. In this case, when the sliding contact edge 83 having the brush portion 85 moves along the inner peripheral surface of the stent portion 80, the thrombus pushed out from the rhombus space of the stent portion 80 toward the inside of the expanded portion 1ep is slidably contacted. The thrombus remaining in the rhombus space can be scraped off by the brush portion 85 while being cut at the edge 83 and taken into the hollow elongated body 1. Thereby, thrombus can be removed more efficiently.
Furthermore, as shown in FIG. 21 (c), the spatula member 82 may have a conical shape in which the outer peripheral portion is located on the proximal side with respect to the axial center portion (center portion). With this configuration, the sliding contact edge portion 83 has an obtuse angle on the distal side and an acute angle on the proximal side. Therefore, when the spatula member 82 moves from the proximal side to the distal side, the sliding contact edge portion 83 is formed. Straddles the thrombus pushed out from the rhombus space of the stent portion 80 toward the inside of the expansion portion 1ep at the obtuse angle portion, while the spatula member 82 moves from the distal side to the proximal side. The thrombus pushed out from the rhombus space of the stent portion 80 toward the inside of the expansion portion 1ep at the acute angle portion of the sliding contact edge portion 83 can be cut and taken into the hollow elongated body 1. Therefore, by moving the spatula member 82 back and forth inside the stent portion 80, the thrombus pushed out from the rhombus space of the stent portion 80 toward the inside of the expanded portion 1ep can be surely removed.
Furthermore, as shown in FIG. 21 (d), the spatula member 82 may be attached to the rail 56 so as to be tiltable. With this configuration, the spatula member 82 can be inclined at an angle according to the inner diameter of the expansion portion 1ep. Therefore, the spatula member 82 can be adapted to changes in the inner diameter of the expansion portion 1ep and various expansion portions 1ep having different inner diameters. Can be made.

FIG. 22 shows a modification of the hollow elongated body according to the sixth embodiment of the present invention.
FIG. 22 shows a modified example of the hollow elongated body according to the sixth embodiment of the present invention in the expanded state of the expanded portion, a cross section taken along the surface along the extending direction of the hollow elongated body, and one end of the hollow elongated body. FIG. 23A to FIG. 23C show cross-sectional views of modifications of the expansion body shown in FIG. 22 and 23, elements similar to those of the hollow elongated body according to the above-described embodiment are denoted by the same reference numerals, and description thereof is omitted.
In the hollow long body 1 ′ ″ ″ according to this modification, the spatula member 82 as an expansion body is fixed to the tip of the operation shaft 70, and is in a contracted state folded into a shape along the operation shaft 70. Further, it is configured to be deformable into a diameter-expanded state that is opened toward the outside in the radial direction and has a rectangular spatula shape that is arranged along the operation shaft 70 and parallel to the operation shaft 70. The radial dimension of the spatula member 82 in the expanded state in a rectangular shape, that is, the outer diameter Rs, is made smaller than the inner diameter re of the expanded portion 1ep, and its outer peripheral edge can be slidably contacted with the inner peripheral surface of the expanded diameter portion 1ep. A sliding contact edge 83 is formed.
In the hollow long body 1 ′ ″ ″ of this modification, the spatula member 82 is expanded in diameter inside the stent portion 80, and in this state, the end portion of the operation shaft 70 is rotated manually or using a rotary drive device or the like. A spatula member that slides the thrombus pushed out from the rhombus space of the stent portion 80 toward the inside of the expanded portion 1ep in the circumferential direction along the inner peripheral surface of the stent portion 80 by rotating the spatula member 82 by operation. It can cut | disconnect with the sliding contact edge 83 of 82, and can take in in the hollow elongate body 1. FIG. Further, by moving the inside of the stent portion 80 from the distal side to the proximal side while rotating the spatula member 82, the entire space of the inner peripheral surface of the stent portion 80 is directed from the rhombus space toward the inside of the expanded portion 1 ep. The extruded thrombus can be cut and removed.

The spatula member 82 shown in FIG. 22 may be configured as shown in FIGS. 23 (a) to (c), for example.
For example, as shown in FIG. 23 (a), the spatula member 82 is directed to a pair of sliding contact edges 83 provided on the outer peripheral portion thereof toward one side in the circumferential direction around the axis of the operation shaft 70. A protrusion 86 having a wedge-shaped projecting cross section may be provided. In this case, by rotating the spatula member 82, the sliding contact edge 83 having the wedge-shaped protrusion 86 is moved in the circumferential direction along the inner peripheral surface of the stent portion 80, so that the expanded portion 1 ep from the rhombus space of the stent portion 80. The thrombus pushed toward the inside can be easily cut by the sharp blade at the tip of the wedge-shaped projection 86. Thereby, thrombus can be removed more efficiently.
Moreover, as shown in FIG.23 (b), the spatula member 82 can also be set as the structure by which the brush part 87 was provided in the sliding contact edge 83 provided in the outer peripheral part. In this case, by rotating the spatula member 82, the sliding contact edge 83 having the brush portion 87 moves in the circumferential direction along the inner peripheral surface of the stent portion 80, so that the expanded portion 1 ep from the rhombus space of the stent portion 80. The thrombus remaining in the rhombus space is cut out from the rhombus space by the brush portion 87 while the thrombus pushed toward the inside is cut by the sliding contact edge 83 and taken into the hollow elongated body 1. Thereby, thrombus can be removed more efficiently.
Further, as shown in FIG. 23C, the spatula member 82 may be configured such that a plurality of spatula members 82 are radially arranged on the operation shaft 70 around the operation shaft 70. Although the case where three spatula members 82 are arranged on the operation shaft 70 is shown in the drawing, it is also possible to adopt a configuration in which a larger number of spatula members 82 are arranged on the operation shaft 70. In this case, by rotating these spatula members 82, the thrombus pushed out from the rhombus space of the stent portion 80 toward the inside of the expanded portion 1 ep by a large number of sliding contact edges 83 provided on each spatula member 82. Can be cut more reliably.

In the case shown in FIGS. 20 to 23, the outer diameter Rs of the spatula member 82 is smaller than the inner diameter re of the expanded portion 1ep, but the outer diameter Rs is larger than the inner diameter re of the expanded portion 1ep. You can also In this case, the spatula member 82 is opened in a diameter-expanded state on the outer side in the extending direction of the hollow long body 1 than the one end 1a of the hollow long body 1, and the open spatula member 82 is opened from the one end 1a side in the blood vessel. By moving toward the other end 1b side, the thrombus adhering to the inner wall of the blood vessel is cut off at the sliding contact edge 83 on the outer side in the extending direction of the hollow elongated body 1 than the one end 1a of the hollow elongated body 1, Thrombus at the site can be taken into the hollow portion 1t of the hollow long body 1 and these thrombus can be cut (subdivided) through the thrombus cutting member 2. In addition, the spatula member 82 will contact | abut to the said one end 1epa, when it reaches to the one end 1epa of the diameter expansion part 1ep.

In the case shown in FIGS. 20 to 23, the stent portion 80 is provided in the extension portion 1ep. However, for example, as shown in FIGS. 2 to 4, the extension portion 1ep in which the stent portion 80 is not provided. The spatula member 82 of this embodiment can also be applied to the hollow elongated body 1 having the above. Further, as the thrombus cutting member 2, members having various configurations such as those shown in FIGS. 5 to 12 can be used.

Further, in the case shown in FIGS. 20 to 23, the thrombus cutting member 2 is provided inside the expansion portion 1ep separately from the spatula member 82, but the spatula member 82 has a function as a thrombus cutting member. Thereby, it can also be set as the structure by which the thrombus cutting member 2 different from the spatula member 82 is not provided in the inside of the expansion part 1ep.

The outer diameter (not shown) of the hollow elongated body 1mp of the hollow elongated body 1 according to the embodiment of the present invention is preferably 1.0 to 3.0 mm, and is 1.4 to 2.7 mm. More preferably it is.
The inner diameter rm of the hollow long body main body 1mp is preferably 0.5 to 2.7 mm, more preferably 1.1 to 2.4 mm.
The inner diameter re of the expanded portion 1ep is preferably 0.6 to 30 mm, and more preferably 10 to 22 mm. If re is 0.6 mm or more, it can be set to a larger value than the inner diameter rm of the hollow long body main body 1mp, and the expanded portion 1ep can be secured. In addition, if re is 30 mm or less, it can be a small value compared with the maximum diameter of a filter used for capturing a thrombus in a vein (for example, an IVC filter placed in the lower aorta), Can be used in combination with a filter.
Furthermore, the length of the hollow elongated body 1 in the extending direction is preferably 500 to 2000 mm, and more preferably 800 to 1500 mm.

The hollow elongate body 1 from the end 1a of the hollow elongate body 1 (one end 1epa of the expanded portion 1ep) to the thrombus cleaving member 2 of the thrombus cutting member 2 provided in the hollow elongate body 1 is located closest to the end 1a. The distance in the extending direction (indicated by L in FIG. 1) is preferably more than 0 mm and 3 mm or less, and more preferably 0.1 mm to 2.0 mm.

The diameter X of the thrombus cutting member 2 is preferably 0.6 to 30 mm, and more preferably 10 to 22 mm.

Examples of materials that can be used for the hollow long body 1mp include flexible polymer materials such as various resins, thermoplastic elastomers, and various rubbers. Various resins include polyolefins such as polyvinyl chloride, polyethylene, polypropylene, ethylene-propylene copolymer, ethylene-vinyl acetate copolymer, polyesters such as polyethylene terephthalate and polybutylene terephthalate, polystyrene, polyurethane, polyamide, polyimide, poly Examples thereof include oxymethylene, polyvinyl alcohol, polytetrafluoroethylene, polyvinylidene fluoride, and other fluororesins. Examples of the thermoplastic elastomer include polyamide elastomer and polyester elastomer. Examples of various rubbers include silicone rubber and latex rubber.

The hollow long body 1 is preferably provided with a radiopaque material (for example, gold, silver, platinum, tungsten, palladium, or an alloy thereof) as a marker at one end 1ap thereof.
According to this configuration, when the hollow long body 1 is inserted into a blood vessel, the position of the one end 1ap of the hollow long body 1 can be confirmed by X-ray irradiation.

The size of the particles that can pass through the thrombus cutting member 2 is preferably 0.6 to 30 mm, and more preferably 2.7 to 22 mm.
Within this range, the thrombus can be sufficiently subdivided, so that it is easy to obtain the effect of the hollow elongated body of the present invention that removes a relatively large thrombus.

Examples of materials that can be used for the thrombus cutting member 2 include elastic bodies such as rubber and thread. According to this configuration, as the expansion portion 1ep expands, the thrombus cutting member 2 can be expanded by the expansion and contraction of the elastic body.

The outer diameter Rb of the balloon 55 is preferably 1 to 31 mm, and more preferably 3 to 23 mm.
When the outer diameter Rb is within the above range, thrombus can be sufficiently captured, and the possibility of damage to the hollow long body due to contact with the hollow long body can be reduced.

The hollow elongated body 1 according to the embodiment of the present invention can be used as a catheter tube to be inserted into a blood vessel or an introducer (sheath) for housing the catheter tube in a medical catheter.

(catheter)
FIG. 1 (a) shows an outline of a catheter according to an embodiment of the present invention in which the hollow long body according to the embodiment of the present invention is used as a catheter tube.
A catheter 100 according to an embodiment of the present invention shown in FIG. 1 includes a hollow long body 1 (catheter tube) according to an embodiment of the present invention and a proximal end of the catheter tube (the other end 1b of the hollow long body 1). A catheter hub 101 provided; a Y-type connector 102 provided at the other end of the catheter hub 101; and a suction device (syringe) 104 connected to a branching portion 102p of the Y-type connector 102 via a connection tube 103. . The catheter 100 also includes a guide wire (not shown) that assists the insertion of the catheter tube into the blood vessel.

Hereinafter, the hollow long body 1 '' according to the third embodiment of the present invention shown in FIG. 1 (a) including the catheter tube made of the hollow long body according to the embodiment of the present invention shown in FIG. 14 will be used. The method of using the catheter according to the embodiment of the present invention will be described with reference to FIGS.
First, using a Seldinger method, a guide wire (not shown) is inserted into a blood vessel (for example, a femoral vein or the like), and then an introducer (sheath) (not shown) is inserted into the blood vessel. Next, a catheter tube composed of the hollow long body 1 '' according to the third embodiment of the present invention is introduced along the guide wire, and the tip of the catheter tube (one end 1a of the hollow long body 1) is connected to one end 1a. Using the marker provided in the above as a reference, it is placed at the site in the blood vessel where the thrombus is removed. In addition, the balloon 55A is introduced along the guide wire, and the deflated balloon 55A is disposed outside the one end 1a of the catheter tube in the extending direction of the catheter tube. Here, the expansion part 1ep of the hollow long body 1 '' is expanded in the radial direction.
Subsequently, the other end side of the Y-type connector 102 is closed by a valve (not shown) provided on the other end side of the Y-type connector 102 connected to the catheter hub 101 of the catheter tube. By sucking the hollow portion 1t using the suction device 104, blood containing a thrombus is sucked. Instead of or together with this suction, the balloon 55A is inflated, and the inflated balloon 55A is displaced from one end 1a side of the catheter tube to the other end 1b side until it contacts the one end 1a of the catheter tube.
At this time, the thrombus in the blood taken into the hollow portion 1t of the catheter is cut (subdivided) by the thrombus cutting member 2 provided in the catheter tube.

The hollow elongated body according to the embodiment of the present invention can be manufactured using a method well known to those skilled in the art.

As described above, the hollow elongated body of the present invention has been illustrated and described with reference to the drawings. However, the hollow elongated body of the present invention is not limited to the above-described example, and the above embodiment is appropriately modified. Can be added.

According to the hollow long body of the present invention, it is possible to provide a hollow long body capable of removing a relatively large thrombi. The hollow long body of the present invention can be suitably used for a catheter tube or an introducer (sheath) of a medical catheter.

1 Hollow long body 1 'according to the first embodiment of the present invention Hollow long body 1' according to the second embodiment of the present invention Hollow long body 1 '''according to the third embodiment of the present invention Hollow long body 1 '''' according to the fourth embodiment of the invention Hollow long body 1 '''''' according to the fifth embodiment of the present invention Hollow long body 1a according to the sixth embodiment of the present invention. One end 1b of the hollow elongated body 1ap The other end 1ap of the hollow elongated body One end 1bp of the hollow elongated body The other end 1ep of the hollow elongated body Expanded portion 1epA of the hollow elongated body Expanded portion 1epB according to the first embodiment Extension part 1epC according to the second embodiment Extension part 1mp according to the third embodiment Hollow long body main body 1epa of the hollow long body One end 1epb of the expansion part of the hollow long body The other end 1t of the expansion part of the hollow long body Hollow Long hollow portion 2 Thrombus cutting member 2A according to the first embodiment Plug cutting member 2B Thrombus cutting member 2B 'according to the second embodiment Modification 2C of the thrombus cutting member according to the second embodiment Thrombus cutting member 2D according to the third embodiment Thrombus cutting member 2E according to the fourth embodiment Fifth Thrombus cutting member 2x Thrombus cutting member 2y Thrombus cutting member 2z Thrombus cutting member 11 Shape memory alloy wire 12 Alloy hollow cylinder 13 Flexible material 14 Outer cylinder member 14a One end 16 of outer cylinder member Outer surface member 17 Tubular portion 18 Fiber member 19 Fiber hollow cylindrical body 20 Flexible material 21 Balloon 31 Threaded members 31a to 31d First thread to fourth thread 35 Foldable member 35 'Foldable members 36a to 36h First side to eighth Side 36 Side 37 Hinge 38 Ring-shaped member 40 Opening and closing member 4 Blades 41a to 41d First blade to fourth blade 42 Blade portions 42a to 42d First blade portion to fourth blade portion 43 Connection portions 43a to 43d First connection portion to fourth connection portion 45 Erecting member 46 Projection 46a to 46d First projection to fourth projection 47 Projection body portion 47a to 47d First projection body portion to fourth projection body portion 48 Coupling portions 48a to 48d First coupling portion to fourth coupling portion 49 Constraint portions 49a to 49d First constraint Part to fourth restraint part 50 Umbrella-shaped member 51 Shaft part 52 Arm parts 52a to 52d First arm part to fourth arm part 53 End part 55 Balloon (expanded body)
55A Balloon (expanded body) according to the first embodiment
55B Balloon (expanded body) according to the second embodiment
55C Balloon (expanded body) according to the third embodiment
56 Rail 60 Stopper 70 Operation shaft 71 Cutter blade 72 Spring-shaped portion 73 Wire 74 Cutter blade 80 Stent portion 81 Wire 82 Spatula member (expanded body)
83 Sliding contact edge 84 Wedge-shaped protrusion 85 Brush part 86 Wedge-shaped protrusion 87 Brush part 100 Catheter 101 according to the embodiment of the present invention Catheter hub 102 Y-type connector 102p Y-type connector branch part 103 Connection tube 104 Suction device rm Hollow length The inner diameter re of the scale body, the inner diameter Rb of the expanded portion in the expanded state, the outer diameter X of the balloon in the expanded state, the diameter A of the thrombus cutting member, the point L between one end and the other end, and from one end of the hollow elongated body to the thrombus cutting member Distances P1 to P8 in the extending direction of the hollow long body Points Q1 to Q8 on the inner peripheral surface of the expanded portion of the hollow long body Points R1 to R4 on the inner peripheral surface of the expanded portion of the hollow long body Points S1 to S4 on the inner peripheral surface of the extended portion of the scale body Points T1 to T8 on the inner peripheral surface of the extended portion of the hollow long body Hollow long body A point on the inner peripheral surface of the extended portion

Claims (9)

A hollow long body inserted into the body,
At one end of the hollow long body, an extended portion that extends in the radial direction of the hollow long body,
A hollow long body comprising a thrombus cutting member for cutting a thrombus in the expansion portion. 2. The hollow long body according to claim 1, wherein the thrombus cutting member has a larger diameter than an inner diameter of the hollow long body body in a state where the expansion portion is expanded. The hollow elongated body according to claim 1 or 2, characterized in that the diameter of the thrombus cutting member increases with the expansion of the expansion portion. The hollow elongated body according to claim 1 or 2, wherein the thrombus cutting member is formed in a state where the expansion portion is expanded. The expansion body that expands in a radial direction of the hollow long body, and the outer diameter of the expansion body is larger than the inner diameter of the expansion portion. The hollow long body described in 1. The expansion body that expands in the radial direction of the hollow long body, and the outer diameter of the expansion body is smaller than the inner diameter of the expansion portion. The hollow long body described in 1. The said expansion body is comprised in the spatula shape opened toward the radial direction outer side from the contracted state, The sliding contact edge which slidably contacts to the internal peripheral surface of the said enlarged diameter part is provided in the outer peripheral part. The hollow long body described in 1. The hollow elongate body according to any one of claims 1 to 7, wherein the thrombus cutting member is provided inside the expansion portion so as to be rotatable relative to the expansion portion. The hollow long body according to any one of claims 1 to 8, wherein a spring-like portion that is elastically deformable in an axial direction is provided at a tip portion of the extension portion.

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