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WO2014148700A1 - Appareil laser pour induire des effets photo-mécaniques et son procédé d'utilisation - Google Patents

Appareil laser pour induire des effets photo-mécaniques et son procédé d'utilisation Download PDF

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Publication number
WO2014148700A1
WO2014148700A1 PCT/KR2013/007345 KR2013007345W WO2014148700A1 WO 2014148700 A1 WO2014148700 A1 WO 2014148700A1 KR 2013007345 W KR2013007345 W KR 2013007345W WO 2014148700 A1 WO2014148700 A1 WO 2014148700A1
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Prior art keywords
photo
laser beam
pulse
per unit
mechanical
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English (en)
Korean (ko)
Inventor
정순철
전재훈
박종락
김형식
정구인
민병찬
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University Industry Cooperation Corporation of Konkuk University
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University Industry Cooperation Corporation of Konkuk University
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
    • H01S3/10038—Amplitude control
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0616—Skin treatment other than tanning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
    • A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity

Definitions

  • the present invention relates to a laser device for generating a photo-mechanical effect, and more particularly, to adjust the energy per unit pulse of the pulsed laser beam to the object to which the laser beam is irradiated
  • a laser device capable of causing mechanical effects A laser device capable of causing mechanical effects.
  • a laser device refers to a device that emits light using light amplification by stimulated emission of radiation.
  • Such a laser device may emit 'artificial light having a uniform direction, phase, and wavelength', which is different from natural light, and is used in many industrial fields based on these characteristics. Specifically, 1) optical communication using optical properties, 2) medical monitoring such as disease monitoring, low level laser therapy, photodynamic therapy, and 3) nanotechnology to separate chemical bonds. 4) It is used in various industrial fields covering precision machine tools such as diamond processing.
  • This invention makes it a subject to provide a laser apparatus which can produce a photo-mechanical effect.
  • Laser device for solving the above problems, outputs a pulsed laser beam (Pulsed laser beam), by adjusting the energy of the pulsed laser beam photo-mechanical effect (Photo-mechanical effect) It is characterized by causing).
  • Pulsed laser beam Pulsed laser beam
  • Photo-mechanical effect Photo-mechanical effect
  • the laser device is characterized by adjusting the energy per unit pulse of the pulsed laser beam to produce a photo-mechanical effect.
  • the laser device is characterized in that the energy per unit pulse is adjusted to a value of 0.005 mJ or more.
  • the laser device is characterized in that the energy per unit pulse is adjusted in the range of 0.005 mJ to 9.5 mJ.
  • the laser device according to an embodiment of the present invention is characterized in that the laser device is utilized for the purpose of presenting a mechanical stimulus to the human body.
  • the laser device is characterized in that the energy per unit pulse is adjusted by adjusting the power (Power) or pulse width of the laser output light.
  • the laser device is characterized in that the pulse width is adjusted in the range of ms (millisecond) or less.
  • the laser device for generating a pulsed laser beam; And a control unit for controlling energy per unit pulse of the pulsed laser beam generated by the laser output unit.
  • the laser device the control unit, the control mode for increasing the photo-mechanical force; And a control mode that reduces the photo-mechanical force.
  • the control unit while adjusting the energy per unit pulse within the range of 0.005 mJ to 9.5 mJ, in the control mode to increase the photo-mechanical force per unit pulse
  • the energy per unit pulse is reduced in a control mode that increases energy and decreases photo-mechanical forces.
  • the haptic device for solving the above problems, while outputting a pulsed laser beam (Pulsed laser beam), by adjusting the energy of the pulsed laser beam photo-mechanical effect (Photo- mechanical effect), and the mechanical touch can be presented using the photo-mechanical effect.
  • Pulsed laser beam Pulsed laser beam
  • Photo- mechanical effect Photo- mechanical effect
  • the haptic device is characterized by adjusting the energy per unit pulse of the pulsed laser beam to produce a photo-mechanical effect.
  • a method for inducing a photo-mechanical effect for solving the above problems, (a) the laser device to adjust the energy of the pulsed laser beam; (b) the pulse laser beam generated by the laser device reaches an object; And (c) generating a photo-mechanical effect by the pulsed laser beam reaching the object.
  • the method of inducing a photo-mechanical effect in the step (a), the laser device, characterized in that to adjust the energy per unit pulse of the pulsed laser beam to cause a photo-mechanical action It is done.
  • the present invention can produce a photo-mechanical effect using a pulsed laser beam. Specifically, the present invention may produce an opto-mechanical effect by adjusting the energy per unit pulse of the pulsed laser beam.
  • the present invention can cause a photomechanical effect on the skin of the human body, in particular by using a pulsed laser beam.
  • the present invention may cause a photo-mechanical effect on the human body by using a pulse laser beam in which the energy per unit pulse is adjusted to a value of 0.005 mJ or more. Therefore, the present invention can be utilized as a device for presenting a mechanical touch.
  • the present invention can produce a photo-mechanical effect without damaging the human skin.
  • the present invention can adjust the energy per unit pulse in the range of 0.0005 mJ to 9.5 mJ, thereby causing a photo-mechanical effect without damaging the human skin.
  • the present invention can increase or decrease the photo-mechanical forces to implement.
  • the present invention provides a photo-mechanical mechanism by increasing or decreasing the energy per unit pulse under the condition that the pulse width of the pulse laser beam is less than millisecond (ms, millisecond) and the energy per unit pulse is 0.005 mJ to 9.5 mJ. You can increase or decrease the force.
  • the present invention can be applied to a haptic device. Specifically, since the present invention can present somethesis to the skin of the human body based on the photo-mechanical effect, it may be applied to the field of haptics. In particular, the present invention can present the somatosensory using photo-mechanical stimulation, not photo-chemical or photo-thermal stimulation of the laser, such as non-contact, etc. It is possible to present somatosensory in a safe state while maintaining the laser's natural characteristics.
  • the present invention when used in the field of haptics, can quantitatively control mechanical stimuli unlike conventional haptic devices.
  • the conventional haptic devices are difficult to quantitatively control the mechanical stimulus because the mechanical stimulus is presented by using a vibration element, air pressure, pin arrangement, etc.
  • the present invention is to control the energy per unit pulse of the laser Mechanical stimulation can be controlled quantitatively.
  • the present invention when used in the field of haptics, unlike conventional haptic devices, the temporal reliability of the mechanical stimulus (reliability of whether the target time point and the actual stimulation time coincidence) or spatial reliability (the target site and the actual stimulation site of Reliability of coincidence) can be secured.
  • the conventional haptic devices have presented a mechanical stimulus using a vibration element, air pressure, pin arrangement, etc., but it is difficult to secure temporal reliability or spatial reliability of the mechanical stimulus.
  • Temporal reliability can be secured using the characteristics of the laser beam, and spatial reliability can also be secured through the fine movement of the laser beam.
  • FIG. 1 is a conceptual diagram showing a photo-mechanical effect that a laser device can produce.
  • FIG. 2 is a block diagram showing the configuration of a laser device according to an embodiment of the present invention.
  • 3 is a conceptual diagram showing parameters of a pulsed laser beam.
  • FIG. 4 is a block diagram showing the configuration of an experimental system for verifying the photo-mechanical effect of the laser device according to an embodiment of the present invention.
  • FIG. 5 is a graph showing an output signal of a piezo sensor.
  • FIG. 6 is a block diagram illustrating a process of processing an output signal of a piezo sensor.
  • 7 and 8 are graphs showing the relationship between 'energy per unit pulse of the laser device' and 'output signal of the piezo sensor' for Experimental Example 1.
  • 9 and 10 are graphs showing a relationship between 'energy per unit pulse of the laser device' and 'output signal of the piezo sensor' for Experimental Example 2.
  • Example 11 is a conceptual diagram showing another experiment (Experimental Example 3) for verifying the photo-mechanical effect of the laser device according to the embodiment of the present invention.
  • optical filter unit 150 lens unit
  • each functional unit represented below is only an example for implementing the present invention. Accordingly, other implementations may be used in other implementations of the invention without departing from the spirit and scope of the invention.
  • each functional unit may be implemented in purely hardware or software configurations, but may be implemented in a combination of various hardware and software configurations that perform the same function.
  • the 'photo-mechanical effect' used below means mechanical stimuli that can be induced by the laser beam.
  • 'mechanical force' or 'mechanical tactile' that can be induced by the laser beam may be included in the 'photo-mechanical effect'.
  • the laser device according to the present invention can cause a photo-mechanical effect through a laser beam. Specifically, by adjusting the parameters of the laser beam that was used only for causing the photo-chemical effect or the photo-thermal effect, the photo-mechanical effect can be induced. Therefore, the laser device according to the present invention can be utilized in various industrial fields requiring mechanical stimulus, and in particular, as a problem (eg, damage to skin tissue) that a photo-chemical effect or a photo-thermal effect can cause. It can also be used as a source of mechanical sensation in somesthesis presentation areas (eg, tactile presentation devices, haptic devices, etc.), where barriers to entry exist.
  • somesthesis presentation areas eg, tactile presentation devices, haptic devices, etc.
  • the laser device generates a laser beam using a pulsed laser rather than a continuous laser (CW laser, continuous wave laser) to generate a photo-mechanical effect, and the generated pulse laser Adjust the energy of the beam.
  • a pulsed laser rather than a continuous laser (CW laser, continuous wave laser) to generate a photo-mechanical effect
  • the generated pulse laser Adjust the energy of the beam.
  • the laser stimulus is provided continuously, a photo-chemical effect or a photo-thermal effect may occur, and thus, a pulsed laser is used to obtain a photo-mechanical effect with these effects minimized.
  • the laser device adjusts the energy per unit pulse of the pulse laser, and generates the photo-mechanical effect of the laser beam through the adjustment operation of this parameter.
  • the photo-mechanical effects that occur based on this phenomenon are undesirable because they can cause skin damage.
  • the energy per unit pulse is adjusted to a small value appropriately, the photo-mechanical effect may be caused by the laser-induced elastic effect rather than the plasma phenomenon and the shock wave phenomenon. Does not cause skin damage. Therefore, it is desirable to limit the energy per unit pulse to a range where skin damage does not occur and to induce an elastic effect (Laser-induced Elastic Effect) by laser absorption.
  • the laser device adjusts the energy per unit pulse in a pulse width condition of ms (millisecond) or less, and generates the photo-mechanical effect of the laser beam based on this adjustment operation.
  • adjusting the energy per unit pulse by the laser device may mean that the laser device changes the energy per unit pulse, but the laser device may change the unit pulse to a specific value (constant value). It may also mean maintaining sugar energy.
  • the operation of 'adjusting' the energy per unit pulse includes not only the operation of changing the energy per unit pulse, but also an operation of maintaining the energy per unit pulse at a specific value (constant value) or a specific range of values. Can be.
  • the present invention 1) an embodiment of changing the energy value per unit pulse to various values (dynamically adjusted between a plurality of values) and 2) an embodiment for maintaining the energy per unit pulse at a constant value every operation ( Can be adjusted to a constant value).
  • the laser device 100 may cause a photo-mechanical effect. Specifically, it may cause a mechanical effect on an object other than the human body as shown in the upper side of FIG. 1, or may cause a mechanical touch to the human body as shown in the lower side of FIG. 1.
  • the laser device 100 for generating a pulse laser beam, the intensity of the optical signal constituting the pulse laser beam (Power, J / The optical filter unit 130 for adjusting the s), the lens unit 150 for adjusting the diameter of the pulse laser beam, the control unit 170 for controlling the operation of the laser output unit, the optical filter unit, the lens unit It may include.
  • the laser apparatus 100 may further include an input unit for receiving information from a user, an output unit for outputting information related to its operation, a communication unit for transmitting and receiving information with external devices, and the like. These components may also be controlled by the controller 170.
  • the laser output unit 110 may output a pulsed laser beam and may include a laser driver, a cooling device, and the like.
  • the laser driver is configured to include a laser medium, an optical pumping unit, an optical resonator, and the like, and generates an optical signal constituting the pulsed laser beam.
  • the cooling device is configured to remove heat that may be generated in the process of generating an optical signal by the laser driver, and serves to protect the laser driver device.
  • the laser output unit 110 may be formed in various forms capable of generating a pulsed laser beam.
  • the laser output unit 110 may be a ruby laser, neodymium: yag laser (Nd: YAG laser), neodymium: glass laser (Nd: glass laser), laser diode (Ga, Al, As), excimer ( Excimer) can be formed in the form of a laser, a dye laser, and the like, in addition to this kind can be configured in various forms.
  • the laser output unit 110 may adjust various parameters of the pulsed laser beam, and in particular, may control energy per unit pulse of the pulsed laser beam in order to generate a photo-mechanical effect.
  • the adjustment of the energy per unit pulse is achieved through the operation of adjusting the intensity (Power, J / s) of the optical signal constituting the pulse laser beam, or adjusting the pulse width of the pulse laser beam. Can be achieved through operation.
  • the pulse width may be adjusted in a range of ms (millisecond) or less.
  • the photo-chemical effect or the photo-thermal effect may be induced as mentioned above. Because there is a possibility.
  • parameters such as optical signal power (Power, J / s), pulse width, pulse repetition rate, and the like of the pulse laser beam may be checked.
  • the laser output unit 110, the energy per unit pulse is preferably adjusted to a value of 0.005 mJ or more. As will be seen later, under these conditions it can cause a photo-mechanical effect on the skin tissue of the human body, and even non-human body can cause a photo-mechanical effect depending on the material.
  • the laser output unit 110 preferably adjusts the energy per unit pulse to a value of 9.5 mJ or less.
  • the degree of the photo-mechanical effect can be large enough to damage the skin tissue of the human body. Therefore, in order to ensure safety in the case of applying a photo-mechanical effect to the human body, it is preferable to adjust the energy per unit pulse to a value of 9.5 mJ or less.
  • the present invention can also be configured in the form of limiting the output of the laser output unit 110 to 9.5 mJ or less.
  • the present invention in the form of controlling the operation of the optical pumping unit to limit the output itself of the laser output unit 110 to 9.5 mJ or less, or 2) additionally a laser blocking film that can block the laser beam.
  • the present invention can be configured in such a manner that the laser blocking film is operated when the energy per unit pulse of the pulse laser exceeds 9.5 mJ.
  • the laser output unit 110 may increase or decrease energy per unit pulse in a range of 0.005 mJ to 9.5 mJ.
  • the intensity of the opto-mechanical forces generated may also increase or decrease.
  • the optical filter unit 130 is a configuration for adjusting the intensity (Power, J / s) of the optical signal constituting the pulse laser beam, the laser output unit 110 outputs through this intensity control The energy can be adjusted secondly per unit pulse of the beam.
  • the optical filter unit 130 may include an attenuator device for attenuating the intensity of the optical signal, and may reduce the intensity (Power, J / s) of the optical signal using such an apparatus. Therefore, the optical filter unit 130 may perform an operation of reducing energy per unit pulse by attenuating the intensity of the optical signal in the same pulse width.
  • the optical filter unit 130 if the laser output unit itself has the ability to adjust the energy per unit pulse may be selectively mounted on the laser device 100, the energy per unit pulse It can play a secondary role in fine tuning. However, when the laser output unit itself does not have the ability to adjust the energy per unit pulse, it is essentially mounted on the laser device 100, thereby playing a leading role in controlling the energy per unit pulse.
  • the lens unit 150 is a configuration for adjusting the diameter (diameter) of the pulse laser beam.
  • the lens unit 150 includes a light focusing unit (for example, a convex lens unit, etc.) for focusing the pulsed laser beam and a light diffusing unit (eg, concave lens unit, etc.) for diffusing the pulsed laser beam.
  • the diameter of the pulsed laser beam may be increased or decreased through selective operation of the light converging unit and the light diffusing unit.
  • the input unit is a component for receiving information necessary for the operation of the laser apparatus 100.
  • the input unit may receive basic information for adjusting various parameters of the pulsed laser beam, and may transfer the received information to the controller 170.
  • the input unit may include a plurality of input keys for receiving a number or a character and setting various functions, and may also include various function keys necessary for the operation of the laser apparatus 100.
  • the input unit may be formed as various types of input devices such as a pad and a touch screen, and may be formed in various devices in addition to the input device.
  • the output unit is configured to display an operation state and an operation result of the laser apparatus 100 or provide predetermined information to a user.
  • the output unit may display information input by the user and information provided to the user, including various menus, and may include various types of liquid crystal displays, organic light emitting diodes, and audio output devices. It may be formed in the form of output devices.
  • the communication unit is configured to allow the laser device 100 to transmit and receive information with external electronic devices.
  • the communication unit may be configured in the form of various wired communication devices or wireless communication devices that satisfy the IEEE standard, and may be implemented in various types of communication devices in addition to the IEEE standard.
  • the laser device 100 may be configured to be controlled by an external electronic device through the communication unit, and may also be configured to operate in conjunction with various electronic devices such as a display device and a mobile terminal. .
  • the laser device 100 including the control unit 170, the laser output unit 110, the optical filter unit 130, the lens unit 150, the input unit, the output unit, the communication unit. To control them.
  • the controller 170 may include at least one arithmetic means and a storage means, wherein the arithmetic means may be a general purpose CPU (CPU), but may be implemented as a programmable device element suitable for a specific purpose. CPLD, FPGA) or application specific semiconductor processing unit (ASIC) or microcontroller chip.
  • the storage means may be a volatile memory device, a nonvolatile memory or a nonvolatile electromagnetic storage device, or a memory inside the computing means.
  • the controller 170 may collectively control the energy per unit pulse of the pulsed laser beam by controlling the operations of the laser output unit 110 and the optical filter unit 130. Specifically, by controlling the operation of the laser output unit 110 and the optical filter unit 130, it is possible to adjust the pulse width (Pulse width) and the intensity (Power, J / s) of the optical signal, The adjustment operation can control the energy per unit pulse.
  • controller 170 may control the operation of the lens unit 150 to adjust additional parameters of the pulsed laser beam.
  • the diameter of the pulsed laser beam may be additionally adjusted through the operation of the lens unit 150.
  • the controller 170 may operate in a control mode for increasing the photo-mechanical force or in a control mode for reducing the photo-mechanical force.
  • the control unit 170 performs a control operation for sequentially increasing the energy per unit pulse, and the pulse laser beam is induced through this operation.
  • the energy per unit pulse is preferably adjusted within the range of 0.005 mJ to 9.5 mJ.
  • the control unit 170 when operating in the control mode for reducing the photo-mechanical force, performs a control operation to sequentially reduce the energy per pulse, through the operation of the pulse laser beam Can reduce the photo-mechanical force.
  • the energy per unit pulse is preferably adjusted within the range of 0.005 to 9.5 mJ.
  • the laser device 100 may generate a photo-mechanical effect by using a pulsed laser beam, and thus may be utilized in various industrial fields requiring mechanical stimulation.
  • the laser device 100 may cause a photo-mechanical effect on skin tissue of the human body, the laser device 100 may be applied to various haptic devices requiring mechanical touch.
  • FIG. 4 is a diagram illustrating a configuration of an experimental system for confirming the photo-mechanical effect of the laser device 100.
  • Such an experimental system may include a configuration of a laser device 100, a collagen film, a piezo sensor, a three-axis position fine adjustment device, a computer, and the like.
  • the laser device 100 is a laser device 100 according to the present invention as described above.
  • a wavelength of 532 nm, a pulse width of 5 ns, a pulse repetition rate of 10 Hz, and a beam diameter of 0.48 mm was used as an embodiment of the laser device 100.
  • the collagen film is a type I collagen film (Neskin®-F, Medira, thickness of 300 ⁇ m to 500 ⁇ m) used for clinical treatment epidermal healing & substitue, modeling human skin tissue. Configuration. Since more than 90% of the living tissue is composed of type I collagen, the collagen film can be used to indirectly experiment with the effects that will occur in living skin tissue.
  • the skin thickness (epidermis) of the human body differs according to individual, sex, and race
  • five collagen films were first conducted, and secondly, collagen films were used. The experiment was conducted. This is because the skin thickness of the human body may vary in the range of 5 to 10 collagen films according to individual, sex, and race. Referring to Table 1, the weight and thickness of five collagen films and ten collagen films can be confirmed.
  • the collagen film was used in the form attached to the piezo sensor.
  • the piezo sensor is an element expressing a mechanical stimulus applied from the outside as an electrical output signal. Therefore, in this experiment, the piezoelectric sensor was used to observe the mechanical change caused in the collagen film.
  • the three-axis position fine adjustment device is a device for finely controlling the position of the piezo sensor.
  • the computer is a device for receiving a signal output from the piezo sensor, analyzing the received signal, and displaying the analyzed result.
  • the pulsed laser beam was irradiated at a frequency of 10 Hz. Specifically, the pulsed laser beam was irradiated immediately before 0.05 [s], immediately before 0.15 [s], immediately before 0.25 [s], and immediately before 0.35 [s].
  • FIG. 5 is a graph showing the results of this experiment.
  • the output signal of the piezo sensor is generated at a frequency of 10 Hz corresponding to the pulse repetition rate of the irradiated laser beam.
  • the time when the output signal is generated by the piezo sensor coincides with the time when the pulse laser beam is irradiated (just before 0.05 [s], just before 0.15 [s], just before 0.25 [s], 0.35 [s], etc.). Can be.
  • the pulsed laser beam caused the photo-mechanical effect.
  • the magnitude of the output signal of the piezo sensor it is also possible to calculate the magnitude of the induced photo-mechanical force.
  • the experiment was conducted with a pulse width of 5 ns that satisfies the range of ms (millisecond) or less. Therefore, the energy per unit pulse by changing the intensity (Power, J / s) of the optical signal constituting the pulse laser beam Changed.
  • the signal output from the piezo sensor was analyzed through a process such as i) pre-processing filtering, ii) low frequency component removal, iii) maximum value detection as shown in FIG. That is, the output signal of the piezo sensor was analyzed through a process of preliminarily filtering to remove noise, secondly removing low frequency components, and detecting a maximum value of the signal. In addition, the results were expressed using the average value of the detected maximum values.
  • FIG. 7 is a graph illustrating a change in an output signal of a piezo sensor according to a change in energy per unit pulse.
  • the horizontal axis is analyzed by setting the energy per unit pulse
  • the vertical axis is analyzed by setting the output signal of the piezo sensor divided by the unit thickness (sensor output signal per unit thickness).
  • FIG. 8 is an enlarged graph of a portion of the graph of FIG. 7. Specifically, FIG. 7 is an enlarged graph of an area surrounded by a dotted line.
  • the skin thickness of ordinary people is in the range of 5 to 10 collagen film. Therefore, applying a pulsed laser beam having an energy per unit pulse of at least 0.005 mJ or more to the human body can cause a photo-mechanical effect regardless of the difference in individual skin thickness.
  • the upper limit for increasing the energy per unit pulse is set to about 9.5 mJ. This is because the collagen film is damaged in the experiment in which the energy per unit pulse is set to 9.5 mJ or more. Therefore, in order to ensure safety when irradiated to the human skin, the energy per unit pulse is preferably limited to the range of 9.5 mJ or less.
  • the output signal of the piezo sensor may also be increased or decreased together. That is, it can be seen that the photo-mechanical force increases as the energy per unit pulse increases in the corresponding range, and the photo-mechanical force decreases as the energy per unit pulse decreases.
  • control operation of increasing or decreasing the photo-mechanical force can be performed through the operation of increasing or decreasing the energy per unit pulse.
  • the pulsed laser was irradiated to the collagen film comprised of 10 sheets using the said laser apparatus 100, and the output signal of the piezo sensor was observed.
  • the experiment was performed while sequentially changing the energy per unit pulse of the pulsed laser beam irradiated by the laser device 100.
  • the signal output from the piezo sensor was analyzed through the process of i) pre-processing filtering, ii) low frequency component removal, iii) maximum value detection.
  • FIG. 9 is a graph illustrating a change in an output signal of a piezo sensor according to a change in energy per unit pulse.
  • the horizontal axis was analyzed by setting energy per unit pulse as in Experimental Example 1, and the vertical axis was analyzed by setting the output signal of the piezo sensor divided by the unit thickness (sensor output signal per unit thickness).
  • FIG. 10 is an enlarged graph of a portion of the graph of FIG. 9.
  • the threshold energy for inducing the photo-mechanical effect on the 5 to 10 collagen films is in the range of 0.00316 mJ to 0.00398 mJ (even if the parameters of the laser are changed). You can check it. In addition, confirming the same conclusion as Experimental Example 1, 'If the pulse laser beam having an energy per unit pulse of at least 0.005 mJ or more applied to the human body, it can cause a photo-mechanical effect irrespective of the difference in individual skin thickness'. Can be.
  • the upper limit for increasing energy per unit pulse was set to 9.5 mJ. This is because, as mentioned in Experimental Example 1, a phenomenon in which the collagen film was damaged was observed in an experiment in which the energy per unit pulse was set to 9.5 mJ or more. Therefore, in order to ensure safety when irradiated to the human skin, the energy per unit pulse is preferably limited to the range of 9.5 mJ or less.
  • the output signal of the piezo sensor may also be increased or decreased together. That is, it can be seen that the photo-mechanical force increases as the energy per unit pulse increases in the corresponding range, and the photo-mechanical force decreases as the energy per unit pulse decreases.
  • the photo-mechanical touch is induced experimentally by the 'pulse laser beam' generated by the laser device 100.
  • a pulse laser beam having a wavelength of 532 nm, a pulse width of 5 ns, an energy per unit pulse of 1.9 mJ, and a beam diameter of 0.48 mm was used.
  • Mechanical stimulation was applied using a rod having the same diameter as the beam.
  • the observation of the EEG using the EEG device was made in the C3 region and the C4 region, which are the body sensory cortex regions of the whole region of the brain.
  • the shape of the EEG response graph when the 'pulse laser beam' is applied is also in the same frequency region of the EEG as in the case where the 'rod stimulation (pure mechanical stimulation)' is applied except for the region in which the response is delayed. It was confirmed that the average size of the EEG increases.
  • the method for inducing a photo-mechanical effect may include the step (a) of the laser device 100 adjusting the energy of the pulsed laser beam.
  • the laser device 100 preferably adjusts the energy per unit pulse of the pulsed laser beam to cause photo-mechanical action.
  • the pulse laser beam generated by the laser device 100 may include a step (step b) of reaching the object.
  • the pulsed laser beam reaching the object may include a step of generating a photo-mechanical effect (step c).
  • the method for inducing the photo-mechanical effect according to the present invention may include substantially the same features as the laser device 100 according to the present invention, although the categories are different.
  • the features described above with respect to the laser device 100 may be naturally inferred and applied to the method for inducing a photo-mechanical effect.

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  • Engineering & Computer Science (AREA)
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  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Biomedical Technology (AREA)
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  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

La présente invention concerne un appareil laser permettant d'induire des effets photo-mécaniques. Plus particulièrement, la présente invention concerne un appareil laser qui peut induire des effets photo-mécaniques en émettant un faisceau laser pulsé tout en ajustant l'énergie pulsée de ce dernier.
PCT/KR2013/007345 2013-03-22 2013-08-14 Appareil laser pour induire des effets photo-mécaniques et son procédé d'utilisation Ceased WO2014148700A1 (fr)

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KR10-2013-0030726 2013-03-22
KR1020130030726A KR101340358B1 (ko) 2013-03-22 2013-03-22 광-기계적 효과를 일으키는 레이저 장치 및 이를 이용한 방법

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KR101648854B1 (ko) * 2015-01-13 2016-08-17 건국대학교 글로컬산학협력단 펄스 레이저를 이용한 체성감각 유도장치
KR101867077B1 (ko) * 2015-01-13 2018-06-15 건국대학교 글로컬산학협력단 펄스 레이저를 이용한 체감유도형 시계
KR101684482B1 (ko) * 2015-11-13 2017-01-11 건국대학교 글로컬산학협력단 2파장 레이저를 활용한 체성감각 유도장치
US10459522B2 (en) 2016-06-15 2019-10-29 Konkuk University Glocal Industry-Academic Collaboration Foundation System and method for inducing somatic sense using air plasma and interface device using them
KR101833834B1 (ko) * 2016-06-15 2018-03-02 건국대학교 글로컬산학협력단 에어 플라즈마를 활용한 체성감각 유도 시스템 및 그 방법
KR101914742B1 (ko) * 2017-04-28 2018-11-02 주식회사 루트로닉 피부 치료용 레이저 장치
US11231783B2 (en) 2019-08-12 2022-01-25 Electronics And Telecommunications Research Institute Apparatus for generating vibrotactile sensation

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