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WO2014097272A3 - Process for the preparation of (s,s)-6-benzloctahydro-1 h-pyrrolo[3,4-b]pyridine,an intermediate of azabicyclopyridine derivatives - Google Patents

Process for the preparation of (s,s)-6-benzloctahydro-1 h-pyrrolo[3,4-b]pyridine,an intermediate of azabicyclopyridine derivatives Download PDF

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Publication number
WO2014097272A3
WO2014097272A3 PCT/IB2013/061274 IB2013061274W WO2014097272A3 WO 2014097272 A3 WO2014097272 A3 WO 2014097272A3 IB 2013061274 W IB2013061274 W IB 2013061274W WO 2014097272 A3 WO2014097272 A3 WO 2014097272A3
Authority
WO
WIPO (PCT)
Prior art keywords
pyridine
pyrrolo
derivatives
benzloctahydro
azabicyclopyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2013/061274
Other languages
French (fr)
Other versions
WO2014097272A2 (en
Inventor
Jigar BHAVSAR
Akhilendra SINGH
Bhuwan Bhaskar
Anil Kumar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MANKIND RESEARCH CENTRE
Original Assignee
MANKIND RESEARCH CENTRE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MANKIND RESEARCH CENTRE filed Critical MANKIND RESEARCH CENTRE
Priority to CN201380066472.0A priority Critical patent/CN105143219A/en
Publication of WO2014097272A2 publication Critical patent/WO2014097272A2/en
Anticipated expiration legal-status Critical
Publication of WO2014097272A3 publication Critical patent/WO2014097272A3/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a cost effective process for the production of (S,S)-6- benzyloctahydro-1H-pyrrolo[3,4-b]pyridine of Formula (I), an important intermediate for the manufacture of azabicyclo pyridine derivatives.
PCT/IB2013/061274 2012-12-21 2013-12-23 Method for production of (s,s)-6-benzyloctahydro-1h-pyrrolo[3,4-b]pyridine, an intermediate of azabicyclo pyridine derivatives Ceased WO2014097272A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201380066472.0A CN105143219A (en) 2012-12-21 2013-12-23 Process for the preparation of (S,S)-6-benzloctahydro-1 h-pyrrolo[3,4-b]pyridine,an intermediate of azabicyclopyridine derivatives

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN3980/DEL/2012 2012-12-21
IN3980DE2012 2012-12-21
IN684/DEL/2013 2013-03-09
IN684DE2013 2013-03-09

Publications (2)

Publication Number Publication Date
WO2014097272A2 WO2014097272A2 (en) 2014-06-26
WO2014097272A3 true WO2014097272A3 (en) 2015-07-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/061274 Ceased WO2014097272A2 (en) 2012-12-21 2013-12-23 Method for production of (s,s)-6-benzyloctahydro-1h-pyrrolo[3,4-b]pyridine, an intermediate of azabicyclo pyridine derivatives

Country Status (2)

Country Link
CN (1) CN105143219A (en)
WO (1) WO2014097272A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105153155B (en) * 2015-09-18 2017-01-18 华东师范大学 Preparation method for 6-benzyl-5,7-dioxo-1,2,3,4-tetrahydro-pyrrolo-[3,4-b] pyridine
CN105777750A (en) * 2016-04-13 2016-07-20 江西中德诚信科技有限公司 Synthesis method for moxifloxacin side chain
CN108623583B (en) * 2018-05-04 2021-01-15 新乡学院 Preparation method of iridium-catalyzed moxifloxacin side chain intermediate
CN114907347A (en) * 2022-07-12 2022-08-16 山东国邦药业有限公司 Preparation method of (4aS,7aS) -6-benzyl octahydro-1H-pyrrolo [3,4-b ] pyridine
CN116217570A (en) * 2023-03-10 2023-06-06 常州大学 Preparation method and application of 6-benzyl-1,2,3,4-tetrahydro-6H-pyrrolo[3,4-B]pyridine-5,7-dione

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101591336A (en) * 2009-06-25 2009-12-02 浙江燎原药业有限公司 8-benzyl-2, the method for reducing of 8-diazabicyclo [4,3,0] nonane and chiral isomer thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3906365A1 (en) 1988-07-15 1990-01-18 Bayer Ag 7- (1-PYRROLIDINYL) -3-CHINOLONE AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES, METHOD AND SUBSTITUTED (OXA) DIAZABICYCLOOCTANES AND NONANESE AS INTERMEDIATE PRODUCTS, AND ANTIBACTERIAL AGENTS AND FOOD ADDITIVES CONTAINING THEM
CA1340553C (en) 1989-07-13 1999-05-18 Uwe Petersen Diazabicyclo compounds
DE19927412A1 (en) * 1999-06-16 2000-12-21 Bayer Ag Process for the enantiomeric enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane
JP2001039979A (en) 1999-07-28 2001-02-13 Koei Chem Co Ltd PRODUCTION OF OCTAHYDROPYRROLO[3,4-b]PYRIDINE
CA2400208A1 (en) 2000-02-17 2001-08-23 Welch Foods, Inc. Calcium-fortified, grape-based products and methods for making them
DE10226923A1 (en) * 2002-06-17 2003-12-24 Bayer Ag Process for the enantiomer enrichment of cis-8-benzyl-7,9-dioxo-2,8-diazabicyclo [4.3.0] nonane
CN101429199B (en) 2008-09-08 2010-12-15 华东师范大学 Process for producing racemic cis-8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4.3.0] nonyl hydride
CN101857199B (en) 2010-05-20 2012-02-08 复旦大学 Method for preparing Al(BH4)3-6NH3 hydrogen storage material
JP2012067033A (en) 2010-09-22 2012-04-05 Kuraray Co Ltd Method for producing aminomethylpyridine derivative
WO2012131629A1 (en) 2011-03-31 2012-10-04 Piramal Healthcare Limited A process for preparation of intermediate of moxifloxacin

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101591336A (en) * 2009-06-25 2009-12-02 浙江燎原药业有限公司 8-benzyl-2, the method for reducing of 8-diazabicyclo [4,3,0] nonane and chiral isomer thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; TU, XIONGFEI: "Reduction method of 8-benzyl-2,8-diazabicyclo[4,3,0]nonane and its chiral isomer", XP002725476, retrieved from STN Database accession no. 2009:1525999 *

Also Published As

Publication number Publication date
CN105143219A (en) 2015-12-09
WO2014097272A2 (en) 2014-06-26

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