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WO2014072820A3 - Dispositifs et procédés chrono-ampérométriques de quantification électrochimique de substances à analyser - Google Patents

Dispositifs et procédés chrono-ampérométriques de quantification électrochimique de substances à analyser Download PDF

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Publication number
WO2014072820A3
WO2014072820A3 PCT/IB2013/002926 IB2013002926W WO2014072820A3 WO 2014072820 A3 WO2014072820 A3 WO 2014072820A3 IB 2013002926 W IB2013002926 W IB 2013002926W WO 2014072820 A3 WO2014072820 A3 WO 2014072820A3
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WO
WIPO (PCT)
Prior art keywords
concentration
methods
devices disclosed
relate
diffusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2013/002926
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English (en)
Other versions
WO2014072820A2 (fr
Inventor
Thomas William Beck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2014072820A2 publication Critical patent/WO2014072820A2/fr
Publication of WO2014072820A3 publication Critical patent/WO2014072820A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/49—Systems involving the determination of the current at a single specific value, or small range of values, of applied voltage for producing selective measurement of one or more particular ionic species

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Electrochemistry (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne des procédés et dispositifs relatifs à l'utilisation d'une électrode en bande, afin de créer un courant à deux composantes dans un capteur électrochimique, à utiliser de préférence avec un glucomètre. Les dimensions de l'électrode en bande sont inférieures à celles de la solution déposée sur elle, un composant du courant résultera donc d'une diffusion planaire et l'autre d'une diffusion de bordure. En analysant les courants tracés, le coefficient de diffusion et la concentration de la substance cible à analyser peuvent être déterminés simultanément, ce qui offre une précision accrue dans le domaine de la mesure de concentration. Les procédés et dispositifs de l'invention concernent également l'utilisation de plusieurs électrodes en bande de différentes largeurs, afin d'augmenter la vitesse de mesure, sans affecter la précision. Les procédés et dispositifs de l'invention concernent en outre l'utilisation de tensions pulsées alternatives, afin de mesurer la concentration d'une substance à analyser, en tirant parti du temps de récupération plus court pour le profil de concentration. Les impulsions alternatives ont également tendance à perturber le profil de concentration dans une seule couche de diffusion fine, ce qui permet d'interroger différentes couches de l'échantillon.
PCT/IB2013/002926 2012-11-08 2013-11-08 Dispositifs et procédés chrono-ampérométriques de quantification électrochimique de substances à analyser Ceased WO2014072820A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261724265P 2012-11-08 2012-11-08
US61/724,265 2012-11-08

Publications (2)

Publication Number Publication Date
WO2014072820A2 WO2014072820A2 (fr) 2014-05-15
WO2014072820A3 true WO2014072820A3 (fr) 2014-07-17

Family

ID=50685266

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/002926 Ceased WO2014072820A2 (fr) 2012-11-08 2013-11-08 Dispositifs et procédés chrono-ampérométriques de quantification électrochimique de substances à analyser

Country Status (1)

Country Link
WO (1) WO2014072820A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI799926B (zh) * 2021-07-28 2023-04-21 五鼎生物技術股份有限公司 電化學檢測系統、測量儀及電化學檢測方法
CN116678928A (zh) * 2022-02-23 2023-09-01 浙江纳智汇生物科技有限公司 一种基于酶抑制法的电化学检测设备、检测系统及检测方法
US20230375495A1 (en) * 2022-05-20 2023-11-23 Lifescan Ip Holdings, Llc Biosensor and related method of manufacture

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110354A (en) * 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
US20070235346A1 (en) * 2006-04-11 2007-10-11 Popovich Natasha D System and methods for providing corrected analyte concentration measurements
WO2010015812A1 (fr) * 2008-08-04 2010-02-11 F. Hoffmann La Roche Ag Amélioration de réponse électrochimique
US20100219084A1 (en) * 2006-10-05 2010-09-02 Stephen Patrick Blythe Method for determining hematocrit corrected analyte concentrations
US20120234700A1 (en) * 2007-07-26 2012-09-20 Nipro Diagnostic, Inc. System and methods for determination of analyte concentration using time resolved amperometry

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110354A (en) * 1996-11-01 2000-08-29 University Of Washington Microband electrode arrays
US20070235346A1 (en) * 2006-04-11 2007-10-11 Popovich Natasha D System and methods for providing corrected analyte concentration measurements
US20100219084A1 (en) * 2006-10-05 2010-09-02 Stephen Patrick Blythe Method for determining hematocrit corrected analyte concentrations
US20120234700A1 (en) * 2007-07-26 2012-09-20 Nipro Diagnostic, Inc. System and methods for determination of analyte concentration using time resolved amperometry
WO2010015812A1 (fr) * 2008-08-04 2010-02-11 F. Hoffmann La Roche Ag Amélioration de réponse électrochimique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JUNG, YONGJU ET AL.: "Simultaneous Determination of Diffusion Coefficient and Concentration by Chronoamperometry at a Microdisk Electrode.", BULLETIN- KOREAN CHEMICAL SOCIETY, vol. 15, 1994, pages 209 - 213 *

Also Published As

Publication number Publication date
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