Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
  • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
  • A23L33/17—Amino acids, peptides or proteins
  • A23L33/175—Amino acids
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P3/00—Drugs for disorders of the metabolism
  • A61P3/02—Nutrients, e.g. vitamins, minerals
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P3/00—Drugs for disorders of the metabolism
  • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
  • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Definitions

• the present invention relates to stable oral pharmaceutical composition, in particular to compositions, which comprises taurine as active agent along with pharmaceutically acceptable excipients preferably in oral dosage form, which is useful as an energy provider booster for all age group.
• Taurine is an amino acid that supports neurological development and helps to regulate the level of water and mineral salts in the blood. Taurine is also thought to have antioxidant properties.
• Some marketed taurine products are Red Bull, Bacchus Energy Drink, BSN NO-Xplode, Gaspari Nutrition, SuperPump250, Muscle Tech, Cell-Tech, Hardcore Pro Series, Double-T ,Sports CreaDyl, Muscle Tech , Nitro-Tech, Hardcore Pro Series, AllMax Nutrition Taurine, Cheap Supplements Taurine, Higher Power L-Taurine XS, NOW Taurine, NOW Taurine Double Strength, NOW Taurine Powder, PrimaForce Taurine, SciFit L-Taurine, Supplement Direct Taurine, Twinlab Mega Taurine thereof.
• Food supplement compositions comprise lipoic acid or a derivative thereof and creatine or a derivative thereof.
• the compositions optionally, but preferably, further comprise of dextrose.
• the food supplement compositions are suitable for supplementing the diet of an athlete and particularly for enhancing an athlete's muscle size or strength.
• aft alertness inducing composition contains the active ingredients caffeine and taurine and various inert substances in a dry formulation.
• Caffeine and taurine are delivered in an oral formulation that obviates the need for ingesting significant quantities of liquid or sugar.
• the instant invention is to provide commercially viable and oral formulation.
• the instant invention is to provide safe and effective dosage form with taurine composition because other ingredients which are using as energy drinks or oral formulation, with high amounts of caffeine or sugar can cause several diseases such as too much caffeine can increase heart rate and blood pressure; interrupt sleep, and cause nervousness and irritability. And added sugar may provide unwanted added calories.
• the instant invention is to increased energy is derived from taurine then the absorption may be faster as comparative to caffeine.
• the instant invention is to provide different release drug profile such as Sustained or controlled or retard formulation available in oral formulation (capsule, tablet, powder and in liquid thereof)
• the taurine is present in an amount of 1000 -1200 mg by weight.
• the said stable oral pharmaceutical composition is available in different drug release profiles such as Sustained or controlled or retard formulation with instant high energy booster oral dosage form such as capsule, tablet, powder and in liquid thereof.
• the first 500 mg of Taurine will disintegrate for the immediate revitalisation and remaining 500 mg to 700mg of Taurine will be available after 12 hours.
• the main active ingredient is taurine
• taurine may have several different roles in the human body. It acts as an antioxidant, and helps prevent macular degeneration and other serious eye diseases. It reduces blood pressure and cholesterol level, thus, helps to prevent arteriosclerosis. It improves detoxification function of the liver. It helps to strengthen the heart muscle, thus, stabilizing the function of the heart. It lessens the accumulation of lactic acid which becomes the cause of fatigue.
• taurine improves glucose tolerance wherein Taurine works by increasing the action of insulin, improving glucose tolerance and enhancing antioxidant levels which are important functions to balance the negative effects of high sugar diets.
• taurine decreases risk of muscle damage wherein large amounts of taurine are also found in muscle, where it is believed to play an essential role. Taurine has shown the ability to lower muscle damage from intense exercise, and improve performance. Exercise depletes the muscles of taurine, making supplementation essential for anyone concerned with getting the maximum benefit from their exercise program.
• Taurine is also used to help improve mental performance and is a common ingredient in energy drinks. Taurine is essential for proper development and growth such as Sports person and Growing /School going Children who needs instant energy thereof.
• This type of supplementation may also be beneficial for the treatment in various diseases for example hypertension, congestive heart failure and diabetes,Congestive heart failure (CHF) ,Hepatitis ,Steatorrhea (fatty, frothy stools) in people with cystic fibrosis ,High blood pressure (hypertension) ,High cholesterol ,Seizures (epilepsy) ,Autism ,Attention deficit hyperactivity disorder (ADHD) ,RetinaI degeneration (an eye condition) ,Diabetes ,Alcoholism thereof.
• the main characteristic of the taurine is that it will not break or damage by heating. However, it dissolves easily in water.
• the taurine supplementation can reduce liver and blood cholesterol levels in the treated group.
• taurine acts an as antioxidant. Antioxidants help protect damage to cells from free radicals wherein Taurine functions as a "potent" antioxidant, wherein Free radicals attack cells in body and can cause chronic conditions such as cancer, eye disease, and possibly diabetes. As many high energy drinks contain caffeine, it may be the caffeine or the combination of caffeine, taurine and/or any other ingredients which give the energy boosting qualities.
• the absorption may be faster if it is in a drink than in food
• L-Taurine may play a useful role in supporting a variety of processes, including:

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• Health & Medical Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Medicinal Chemistry (AREA)
• Diabetes (AREA)
• Veterinary Medicine (AREA)
• Public Health (AREA)
• Engineering & Computer Science (AREA)
• General Health & Medical Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• Pharmacology & Pharmacy (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• Organic Chemistry (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Bioinformatics & Cheminformatics (AREA)
• General Chemical & Material Sciences (AREA)
• Nutrition Science (AREA)
• Obesity (AREA)
• Hematology (AREA)
• Endocrinology (AREA)
• Proteomics, Peptides & Aminoacids (AREA)
• Mycology (AREA)
• Emergency Medicine (AREA)
• Food Science & Technology (AREA)
• Polymers & Plastics (AREA)
• Epidemiology (AREA)
• Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

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Citations (7)

• 2012
  • 2012-11-06 WO PCT/IN2012/000727 patent/WO2013118136A1/fr not_active Ceased

Patent Citations (7)

Non-Patent Citations (3)

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