WO2013041005A1 - Detector and analyzer for medical tests - Google Patents

Abstract

A detector and analyzer for medical tests, comprising a main control device (10) and a test device (100), wherein the main control device (10) comprises a power supply device (11), a control device, an output device for test results, and a storage cavity (15), and the test device (100) comprises a carrier platform (102) and a light source emitting and receiving device (103). The test device (100) is placed inside the storage cavity (15) of the main control device. The light source emitting and receiving device (103) moves close to and away from the carrier platform in a direction roughly perpendicular to the moving direction of the carrier platform (102), detects parameters about the change in colour of a detecting element on the carrier platform, and then transfers the parameters to the control device, which parameters are used for the output of examination results after being processed by the control device. The test device can transport the carrier platform to a proper test position for the light source stably and accurately, resulting in accurate examination results.

Description

 Medical detection analyzer

Technical field

The invention relates to a medical detection analyzer, in particular to a medical detection analyzer for detecting biochemical indicators of a sample.

Background technique

With the advancement of science and technology, bedside in vitro diagnostic experiments in the field of laboratory medicine (POCT: Point of Care Testing) came into being and developed rapidly. The "dip-and-read" dry chemical method that appeared in the 1950s refers to the direct addition of a liquid test sample to a dry reagent strip, using the moisture of the sample to be tested as a solvent on the reagent strip. A specific chemical reaction to perform a sample analysis method. The biochemical dry test paper method also plays an important role in rapid on-site detection because of its convenient carrying, simple operation and fast measurement speed. With the introduction of immune response and molecular biotechnology, the field of medical dry test strips has expanded to include blood glucose, pregnancy, hemagglutination, myocardial damage, acid-base balance, infectious diseases, and therapeutic drug concentration monitoring (TMD). ), alcohol content testing, blood coagulation test, analysis of biochemical indicators in blood, screening of infectious diseases, hormone levels during surgery, microchip DNA diagnosis and drug abuse detection. The visual test method is used to judge the test result of the dry chemical test paper, which can only be used as a qualitative judgment or a semi-quantitative judgment. Therefore, in order to make the interpretation of the rapid test strips more accurate, the miniaturized detection instruments matched with them are gradually developed. These instruments are easy to operate and produce fast and accurate results. And the data obtained by these instruments can also be transmitted over long distances to the laboratory computer management system or form an electronic medical record.

US Patent US 4780283 discloses a dry chemical test strip analyzer. The analyzer includes a stationary detection light source and a working platform for loading the hemispherical surface of the test strip. The hemispherical working platform is transported to the detection source by the interaction between the springs for detection. Since only the mechanical force between the springs is utilized, not only the production process requires a very precise control process, but also the production cost is increased, and it is difficult to control the correct position between the reaction reagent strip and the detection light source by the interaction of the springs. , affecting the test results. The structure of the hemisphere increases the volume of the entire analytical instrument. On the other hand, the spring has a short service life and requires periodic replacement of the spring, which causes trouble for the user of the instrument.

American Praxsys Biosystems Inc. The company has developed a rapid immunoassay system that can be used for qualitative and quantitative judgments, as disclosed in U.S. Patent No. 6,136,610, which consists of a tester and associated test strips. The system uses a single channel, which means that only a single patient sample can be detected at a time. Since the test instrument can only detect one indicator at a time, the detection efficiency is relatively low.

Chinese patent application 200910160639.5 discloses a multi-channel portable colloidal gold test paper rapid test device, which mainly comprises: four independent detection channels, an ARM data processor, a keyboard and an LCD part. The detection device of the invention can perform a variety of detection projects quickly and with high throughput. However, the four independent detection channels of the Chinese patent application and the entire detector are integrated, and the instrument user cannot replace the test item by replacing the detection channel.

Chinese patent application 200410052202.7 discloses a rapid diagnostic sidestream analysis system and method, which comprises a main unit and 1 to 20 test modules, and is connected to a computer host through a USB or Bluetooth wireless receiver, and the computer host passes the software. Control the detector to run. The patent application also discloses that the main unit and the test module are designed to be relatively independent. When the main unit fails, all test devices can be disassembled and reassembled with the other main unit. The removal of the test module described in this patent application from the main unit is a very complicated process requiring many components to be opened. On the other hand, the test module is not a closed structure. When the test sample or test reagent remains in the test module that has been removed, the residual sample or reagent will be exposed to the environment, not only pollution. The surrounding environment also poses a danger to the safety of the operator.

In existing detectors, they are often single-channel, that is, only a single patient sample can be detected at a time. This single-channel tester has a limited number of samples tested per unit time, and it often causes a large amount of retention of medical examiners when dealing with a large number of large-scale physical examinations.

During the sample loading process, the test paper is first placed on the experimental table, and then the sample is dropped. Since the test paper will be thinner and will stick to the test table, when the sample is added, it will be difficult to take up the test paper again, which takes more time and delays the correct detection time.

On the other hand, if the operator makes a mistake, the test program is turned on without closing the test door, so that external interference light will enter the test site, resulting in inaccurate test results, especially the detector using the optical detection principle.

Summary of the invention

One of the objects of the present invention is to provide a test apparatus for medical examination comprising a base 101, a movable stage 102 designed to transport test elements on the base 101, and a movable unit above the stage 102. Light source transmitting and receiving device 103, the stage 102 can reciprocate in a preset track, the light source transmitting and receiving device 103 can be moved closer to and away from the stage 102, the movement path or movement of the stage 102 and the light source transmitting and receiving device 103 The extension lines of the tracks intersect each other in the same plane or the orthographic projections in the same plane cross each other.

The test apparatus, wherein when a certain fixed area on the stage 102 is located just at the orthographic projection of the light source transmitting and receiving device 103, the stage 102 stops moving, and then the light source transmitting and receiving device 103 approaches the stage 102. That fixed area is tested, and the detection is completed and then away from the fixed area on the stage 102.

The test device, wherein the test device further comprises at least one bracket 104 fixedly mounted on the base 101, the light source transmitting and receiving device 103 being designed on the bracket 104.

The test device, wherein the test device includes at least two motors that drive the stage 102 and the light source transmitting and receiving device 103, respectively.

The test device, wherein the electric motor is a stepper motor 107, 130.

The test apparatus, wherein a rack plate 111 is fixed on the stage 102, and a stepping motor 107 with a gear 108 is mounted on the bracket, the gear 108 on the stepping motor and the teeth on the stage 102 The strip 111 is meshed and connected to drive the stage 102 to move.

In the test device, a left bracket 104 and a right bracket 105 are designed on the base 101, and an upper bracket 106 is designed on the left bracket and the right bracket, and the light source transmitting and receiving device 103 is designed on the upper bracket 106.

The test apparatus, wherein the light source transmitting and receiving device 103 includes a light source emitting device 131, a light receiving device, and an optocoupler switch 132 that controls movement of the light source transmitting and receiving device.

The test device, wherein the diaphragm switch 132 has a light-emitting hole 133, and the light-emitting device and the receiving device have a shielding plate 134. The shielding plate 134 has a shielding light-emitting hole 133 and an exiting light-emitting hole 133 with respect to the light-emitting hole 133. Two locations.

In the test device, when the light source transmitting and receiving device 103 is running downward, when the shielding plate 134 is located above the light emitting hole 133 of the diaphragm switch 132, the light path is unblocked, and the power source is always kept in a power supply state, so that the light source emitting device is enabled. 131 continues downward movement under the rotation of the electric motor 130. When the shielding plate 134 blocks the light emitting hole 133 of the diaphragm switch 132, the optical path is cut off, thereby turning off the power of the electric motor 130 of the light source transmitting and receiving device 103, and turning on the light source. The transmitting and receiving device 103 performs analysis of the samples.

In the test device, the base 101 is fixedly designed with a rail seat 112, and the carrier 104 is fixedly designed with a guide rail 113, and the guide rail 113 is slidably combined with the rail seat 112.

A second object of the present invention is to provide a medical detection analyzer comprising a main control device 10 and at least one test device 100, wherein the main control device 10 includes a power supply device 11, a control device, a detection result output device, and not less than A storage chamber 15 for testing the number of devices, the test device 100 includes a stage 102 for carrying the detecting element and the detecting sample, and a light source transmitting and receiving device 103 located above the stage 102. The testing device 100 is placed in the storage of the main control unit. The cavity 15 is electrically connected to the power supply device 11, the control device and the detection result output device of the main control device, and the control device controls the stage 102 of the test device to reciprocate in a certain direction, and the light source transmitting and receiving device 103 is on the stage 102. Moving in a direction substantially perpendicular to the direction of movement, moving away from the stage, and detecting a color change parameter of the detecting element placed on the stage 102, and then transmitting the parameter to the control device, after being processed by the control device, passing the detection result The output device outputs the detection result.

In the medical detection analyzer, the testing device 100 can be repeatedly extracted and incorporated into the main control device 10.

In the medical detection analyzer, a slide rail structure is designed between the outer wall of the test device 100 and the inner wall of the storage chamber 15 of the main control device 10.

The medical detection analyzer, wherein the slide rail structure comprises a guide rail 16 and a slider structure 120 disposed on an inner wall of the storage chamber 15 and an outer wall of the test device, and the slider structure 120 can slide in the guide rail 16 of the storage chamber 15. .

The medical detection analyzer includes two or more test devices 100, each of which can detect the same or different parameters of the same type of detection samples, and can also detect the same or different parameters of different types of detection samples.

The medical detection analyzer further includes at least one reagent storage unit 18 in which a plurality of detection elements can be placed.

The medical detection analyzer, wherein the storage chamber 15 in the main control device 10 can selectively accommodate the testing device 100 or the reagent storage unit 18, that is, the storage chamber 15 can not only accommodate the testing device 100, but also the reagent storage unit. 18.

The medical detection analyzer, wherein the detection result output device comprises a printer 14 and/or a display 13.

The medical detection analyzer, wherein the control device comprises a touch screen display 13, the touch screen display 13 providing an operation interface.

The medical detection analyzer further includes a locking device that locks or releases the main control device 10 and the testing device 100.

The medical detection analyzer, wherein the locking device comprises three permanent magnetic blocks, wherein the first and second magnetic blocks are disposed on a casing of the main control device 10, and the third magnetic block is fixed to the testing device 100. The outer casing, when the test device is sufficiently housed in the storage chamber 15 of the main control device, the three magnetic blocks are arranged substantially in a straight line, the second magnetic block is located between the first and third magnetic blocks, the second and the third The opposite poles of the magnetic block are opposite in magnetic polarity (for example, one is an S pole and the other is an N pole), and the first magnetic block is magnetically opposite to the second magnetic pole (for example, all N or S poles), The first magnetic block can move along the line connecting the three magnetic blocks with the test device (100).

A third object of the present invention is to provide a biochemical analyzer comprising a main control device 10 and at least one test device 100. The main control device 10 includes at least one storage chamber 15 in which the test device 100 is housed. The storage chamber 15 is designed with a guide rail 16 which is designed with a slider structure that can slide within the guide rail 16 of the storage chamber 15 to smoothly remove the test device 100 from the storage chamber 15 or The test device 100 is assembled into the storage chamber 15.

In the biochemical analyzer, the two side walls of the storage chamber 15 are respectively designed with a guide rail 16, or a guide rail 17 is designed at the bottom of the storage chamber, or a guide rail is designed on both side walls and the bottom of the storage chamber.

The biochemical analyzer, wherein the slider structure comprises a slider holder 120 designed on a side of the test device base 101, and a slider 121 is disposed in the slider holder 120, and the slider 121 can be stored The guide rail 16 of the cavity 15 slides.

The biochemical analyzer, wherein the slider structure comprises a slider holder 120 designed at the bottom of the test device base 101, and a slider 121 is disposed in the slider holder 120, and the slider 121 can be in the storage chamber. The guide rail 17 of 15 moves inside.

The biochemical analyzer comprises two or more test devices 100 and a storage chamber 15 having a number of not less than the number of test devices.

The biochemical analyzer, wherein the test devices 100 are independent of each other.

The biochemical analyzer further includes at least one reagent storage unit 18, at least one storage chamber 15 for accommodating the reagent storage unit 18, and the remaining storage chambers for accommodating the test device 100.

In the biochemical analyzer, the reagent storage unit has a reagent storage rack 19 therein.

The biochemical analyzer, wherein the test device 100 or the reagent storage rack 19 and the main control device 10 are mutually engaged by a magnetic block locking structure.

The biochemical analyzer, wherein the magnetic block locking structure comprises three permanent magnet magnetic blocks, wherein the first magnetic block 151 and the second magnetic block 152 are disposed on a casing of the main control device 10, and the third magnetic block 153 is fixed to the outer casing of the testing device 100. When the testing device is sufficiently housed in the storage chamber 15 of the main control device, the three magnetic blocks are substantially aligned in a straight line, and the second magnetic block 152 is located in the first magnetic block 151 and the first Between the three magnetic blocks 153, the opposite magnetic poles of the second magnetic block 152 and the third magnetic block 153 are opposite in polarity (for example, one is an S pole and the other is an N pole), and the first magnetic block 151 and the second magnetic block The opposite magnetic poles of the 152 are the same (for example, all of the N poles or the S poles), and the first magnet block 151 can move along the line connecting the three magnet blocks.

The biochemical analyzer, wherein the first magnet block 151 is designed on the test device tailgate 126, the second magnet block 152 is designed in the main control device 10, and two support frames are designed on the back cover of the main control device. 154. The third magnet 153 is connected to the support frame 154 by a spring piece 155.

In the biochemical analyzer, the main control device 10 further includes a main power source 11, a main switch 12, an operation panel 13, and a printer 14, and the main switch 12, the operation panel 13, and the printer 14 are electrically connected to the main power source 11.

The biochemical analyzer, wherein the main control device 10 further comprises a USB interface 19, a fan 20 and a total power inlet 21 .

The biochemical analyzer, wherein the testing device 100 comprises a base 101, a carrier 102 for transporting the test strip on the base 101, and a light source transmitting and receiving device 103 above the stage 102, on the base 101. At least one bracket is fixedly designed, the light source transmitting and receiving device 103 is designed on the bracket, and at least one side of the carrier 102 is fixedly designed with a rack plate 111 on which a stepping motor 107 is designed. The gear 108 on the stepping motor is meshed with the rack plate 111 on the stage 102. The stepping motor drives the gear to rotate, and the gear drives the stage to move within the testing device.

The biochemical analyzer, wherein the light source transmitting and receiving device 103 includes a motor 130 that pushes the light source emitting device 131 up and down, a light source emitting device 131, a light receiving device, and an optocoupler switch that controls a moving position of the light source transmitting and receiving device. 132.

The biochemical analyzer, wherein the main control device 10 is in electrical communication with the testing device 100.

The biochemical analyzer, wherein the main control device 10 and the testing device 100 are connected by a power connector 140.

Another object of the present invention is to provide another biochemical analyzer, including a main control device 10 and a test device 100 electrically connected to the main control device 10, wherein the main control device 10 includes a power supply device 11 and a control device, and is tested. Apparatus 100 includes a movable stage 102 and a light source transmitting and receiving device 103 positioned above and below the stage for movement adjacent and away from the stage.

The biochemical analyzer, wherein the control device comprises an operation panel 13 hingedly connected to a casing of the main control device 10, and the operation panel 13 can be flipped 0-180 degrees with a hinge as a rotation axis.

In the biochemical analyzer, the operation interface of the operation panel 13 is downward, and when the operation panel 13 is rotated 90-180 degrees with the hinge as a rotation axis, the operation panel 13 is in an open state.

In the biochemical analyzer, the operation interface of the operation panel 13 is upward, and when the operation panel 13 is flipped by 0-90 degrees with the hinge as the rotation axis, the operation panel 13 is in an open state.

The biochemical analyzer, wherein the operation panel 13 is provided with a bracket 24, the two ends of the bracket 24 abut against the outer casing of the operation panel 13 and the main control device 10, respectively, so that the operation panel 13 and the outer casing of the main control device 10 are kept between The angle between 0-90 degrees.

The biochemical analyzer, wherein the operation panel 13 is an LCD or an LED display panel.

The biochemical analyzer, wherein the operation panel 13 is a touch screen LCD or an LED display panel that can perform touch screen operation.

In the biochemical analyzer, the main control device 10 is provided with a storage chamber 15, and the test device 100 is inserted into or withdrawn from the storage chamber by a drawer.

In the biochemical analyzer, the inner wall of the storage chamber 15 and the outer wall of the testing device 100 are provided with interfitting rail devices.

The biochemical analyzer, wherein the slide rail structure comprises a rail 16 and a slider structure 120, the slider structure being movable on the rail.

A fifth object of the present invention is to provide a magnetic block lock structure comprising at least three permanent magnet magnetic blocks, wherein the first magnetic block 151 is fixed on the first device, and the second magnetic block 152 is fixed on the second device. The third magnet block 153 is movably disposed on the second device. When the first and second devices are in close proximity to each other, the three magnet blocks are substantially aligned in a straight line, and the second magnet block 152 is located in the first magnet block 151. Between the third magnet block 153 and the third magnet block 153, the opposite poles of the second magnet block 152 and the third magnet block 153 are magnetically identical (for example, all of the N poles or the S poles), and the first magnet block 151 is opposite to the second magnet block 152. The two poles are magnetically different (for example, one is an S pole and the other is an N pole), and the third magnet block 153 is movable along a line connecting the three magnetic blocks.

In the magnetic block locking structure, the second device is provided with two brackets 154 and two spring ends 155 movably connected to the bracket 154. The third magnet block 153 is fixedly connected with the spring piece 155.

The magnetic block locking structure, wherein the second device is provided with two sliding bars 156 and a sliding bar buckle 157 sleeved on the sliding bar 156, and the third magnetic block 153 can pass through the sliding bar buckle 157 on the sliding bar 156. Swipe up.

In the magnetic block locking structure, the second device is provided with two springs 158, and the third magnetic block 153 is connected to the spring 158 through the spring buckle 159.

A sixth object of the present invention is to provide a method for locking and separating two devices by using a magnetic block lock structure, the magnetic block lock structure comprising at least three permanent magnet magnetic blocks, wherein the first magnetic block 151 Fixed on the first device, the second magnet block 152 is fixed on the second device, and the third magnet block 153 is movably disposed on the second device. When the first and second devices are in close proximity to each other, three The magnetic blocks are arranged substantially in a straight line, the second magnetic block 152 is located between the first magnetic block 151 and the third magnetic block 153, and the opposite poles of the second magnetic block 152 and the third magnetic block 153 are magnetically identical (for example, all N pole or S pole), the two poles of the first magnet block 151 and the second magnet block 152 are magnetically different (for example, one is an S pole and the other is an N pole), and the third magnet block 153 can be along three magnetic blocks. The method of moving, the method comprising the steps of: 1) approaching a first device to which the first magnetic block 151 is fixed to a second device to which the second magnetic block 152 is fixed, and making the third The magnetic block 153 is kept far enough apart from the second magnetic block 152, and the first magnetic block 151 and the second magnetic block 152 pass The forces are attracted together to lock the first device and the second device to each other; 2) pushing the third magnet block 153 toward the second magnet block 152, the third magnet block 153 and the second magnet block 152 and the first magnet block The mutual repulsive force between 151 weakens the magnetic attraction between the first magnet block 151 and the second magnet block 153, thereby separating the first device and the second device from each other.

A seventh object of the present invention is to provide a biochemical analyzer having a magnetic block lock structure, comprising a main control device 10 and a test device 100. The main control device 10 is provided with a storage cavity 15, and the test device 100 is housed in the storage cavity. The magnetic block locking structure includes at least three permanent magnet magnetic blocks, wherein the first magnetic block 151 is fixed on the testing device 100, and the second magnetic block 152 is fixed on the main control device 10, The three magnetic blocks 153 are movably disposed on the main control device 10. When the main control device 10 and the testing device 100 are in close proximity to each other, the three magnetic blocks are substantially aligned in a straight line, and the second magnetic block 152 is located in the first magnetic field. Between the block 151 and the third magnet block 153, the opposite poles of the second magnet block 152 and the third magnet block 153 are magnetically identical (for example, all of the N poles or the S poles), and the first magnet block 151 and the second magnet block 151. The opposite poles of the 152 are magnetically different (for example, one is an S pole and the other is an N pole), and the third magnet block 153 is movable along a line connecting the three magnetic blocks.

In the biochemical analyzer, two support frames 154 are designed on the main control device 10. The third magnetic block 153 is connected to the support frame 154 via the spring piece 155.

In the biochemical analyzer, the main control device 10 is designed with two sliding bars 156, and the third magnetic block 153 can slide on the sliding bar 156 through the sliding bar buckle 157.

In the biochemical analyzer, the main control device 10 is designed with two springs 158, and the third magnetic block 153 is in contact with the spring 158 through the spring buckle 159.

An eighth object of the present invention is to provide a test method for measuring biological sample parameters by using a biochemical analyzer, the test method comprising the following steps: 1) turning on the power, the biochemical analyzer is turned on and entering the self-test step; 2) the self-test After passing, the biochemical analyzer enters the preheating step; 3) when the test temperature of the biochemical analyzer meets the preset temperature condition, prompting to put the test component and the test sample; 4) the biochemical analyzer starts the test; 5) the test is completed. After that, the test result is output; 6) prompting to take out the used test component and test sample; 7) prompting whether the test is finished; 8) if the selection is not finished, prompting to put a new test component and test sample, and then repeating step 4) -6); 9) If the selection is over, shut down and end the test.

The test method, wherein the biochemical analyzer comprises a master device 10 and at least one test device 100, and the step of self-testing comprises checking whether the state of each device is normal, and checking the number of test devices 100.

The test method, wherein when the number of test devices 100 is equal to or greater than two, after the step of passing the self-test and before the warm-up step, the step of selecting which one or which test devices 100 to test is included .

The test method includes a step of selecting a test type to be performed by the selected test device 100 after the step of testing the test device 100 is selected or after the warm-up step.

The test method includes the steps of automatically determining the type of test to be performed on the selected test device 100 after the test component and the test sample are placed and before the analyzer starts the test.

In the test method, the test component is provided with the indication information of the test type, and the biochemical analyzer automatically determines the test type after reading the indication information on the test component.

In the test method, after the test device 100 completes the test, the biochemical analyzer prompts whether the test is finished. If the selection is finished, the test device 100 is turned off. If no selection is made, the test device 100 is replaced. Close after a predetermined period of inactivity.

The test method described above, wherein the biochemical analyzer is turned off when all of the test devices 100 are turned off.

In the test method, a guide rail is disposed between the main control device 10 of the biochemical analyzer and the at least one test device 100, and at least one test device 100 can slide within the main control device 10.

The test method, wherein the biochemical analyzer further comprises a reagent storage unit 18 having the same contour or size as the test device 100, and the main control device 10 is provided with a contour and a size and test device 100 and a reagent storage unit 18 The matching storage chamber 15 can selectively receive the testing device 100 or the reagent storage unit 18, that is, the storage chamber 15 can accommodate not only the testing device 100 but also the reagent storage unit 18.

In the test method, a guide rail is disposed between the reagent storage unit 18 and the main control device 10.

A ninth object of the present invention is to provide a biochemical analysis tester comprising a main control unit and at least two independent test units, the main control unit being respectively connected with the main power control switch, the data output/input control system and the test unit. Each test unit includes at least a sample sending device and a light source device, the light source device includes a test light source and an upper pressing plate, and the sample feeding device includes a test paper tray, an electric motor that pushes the movement of the test paper tray, and a control test paper tray to reach the detection position. The switch has a heating device.

The biochemical analysis tester has a test unit door corresponding to each test unit, and the operation of closing a test unit door can automatically start the corresponding test unit to work.

The biochemical analysis tester is provided with a magnetic induction starting device in each test unit, and the magnetic induction starting device comprises a magnetic block disposed on the test unit door and a magnetic induction switch disposed in the test unit.

The biochemical analysis tester comprises a casing for fixing the main control unit and the test unit, and the test case is provided with a test paper loading console.

In the biochemical analysis tester, the test paper operation table is a card slot structure, including an upper plate and a lower plate, and a gap is left between the upper plate and the lower plate to facilitate insertion of the test paper.

The biochemical analysis tester, which controls the test paper tray to reach the detection position, is an optocoupler switch.

A tenth object of the present invention is to provide a biochemical analysis test method, comprising:

1) Turn on the biochemical analysis tester and set test parameters, the biochemical analysis tester includes a main control unit and at least two independent test units, and the main control unit and the main power control switch, the data output/input control system, and The test units are connected to each other, and each test unit includes a sample sending device and a test light source device;

2) Put the test paper with the sample added into one of the test units;

3) The biochemical analysis tester determines whether there is a test paper in the detection area;

4) The biochemical analysis tester determines whether the test unit door is closed;

5) When the test paper is already present in the detection area and the unit door is closed, both sets of information are available, and the biochemical analysis tester starts the detection and outputs the detection result.

The test method, wherein the biochemical analyzer further determines whether the detection start time exceeds a preset time; if timeout, the biochemical analysis tester gives a prompt to re-replace the test paper; if not, The biochemical analysis tester starts the detection and outputs the test results.

The test method, wherein the test light source emits the test light, and determines whether the test area has the test paper by the reflected light information in the tray detection area; if not, the biochemical analysis tester gives the prompt information for repositioning the test paper.

The test method, wherein a magnetic induction starting device is arranged in the testing unit, and the magnetic induction switch senses a magnetic field signal of the magnetic block on the unit door, and after the magnetic field signal is transmitted to the main control unit, the main control unit determines the specificity of the unit door. Position, if the unit door is not closed, the biochemical analysis tester gives information to re-close the unit door.

An eleventh object of the present invention is to provide a biochemical analysis tester comprising a casing, a test unit fixed to the casing, and a test unit door corresponding to the test unit, wherein the test unit includes a temperature control device and mechanical movement The control device and the detecting optical path device are characterized in that the test unit and the corresponding test unit door are provided with a magnetic induction starting device that automatically starts the test unit to operate by closing the test unit door.

The biochemical analysis tester, wherein the magnetic induction starting device comprises a magnetic block disposed on the test unit door and a magnetic induction switch disposed in the test unit, and when the test unit door is closed, the magnetic block on the test unit door is disposed adjacent to The magnetic induction switch in the test unit turns on the magnetic induction switch, thereby starting the test unit to work.

The biochemical analysis tester, wherein the magnetic block material is magnetic steel.

The biochemical analysis tester, wherein the magnetic block is fixed on the unit door by means of adhesive fixing or screwing.

The biochemical analysis tester, wherein the magnetic block is enclosed in the unit door or placed outside the unit door.

The biochemical analysis tester, wherein the sample delivery device comprises a tray carrying a test strip, and a heat transfer plate is disposed under the tray, and the heat generated by the heating device is transmitted to the detection area through the heat transfer plate. A lower pressing block insulation plate is placed under the temperature heating device to block the heat generated by the heating device. The electric motor is fixed on the electric motor fixing plate, and the pushing tray sends the detection test strip to a preset detection position. .

The biochemical analysis tester also includes an optocoupler switch for controlling the tray to a predetermined detection position.

The biochemical analysis tester, wherein the heating device is selected from a power resistor plate.

The biochemical analysis tester includes at least two test units, each test unit corresponding to one of the test unit doors and one of the magnetic induction starting devices.

A twelfth object of the present invention is to provide a biochemical analysis tester comprising a casing and a main control unit and a test unit mounted in the casing, wherein a test paper loading console is mounted on the casing.

The biochemical analysis tester, wherein the console is a card slot type structure.

The biochemical analysis tester, wherein the operation table is composed of an upper plate and a lower plate, and a gap is left between the upper plate and the lower plate, which is suitable for measuring the insertion of the test paper.

The biochemical analysis tester includes at least two independent test units.

Due to the adoption of the above technical solutions, the present invention brings about the following beneficial effects:

The test device is mounted on the main control device or the test device is detached from the main control device by the movement of the slider on the test device in the test device. This operation is simple and convenient.

Since the reagent storage unit can also be accommodated in the storage chamber, the operator can place the required reagent in advance in the reagent holder of the reagent storage unit, and the required reagent can be conveniently taken out from the reagent storage rack during the detection. If a certain type of test device is used for a long time, the corresponding reagent storage unit can also be stored in the main control device for a long time, forming a one-to-one relationship with the test device to prevent misuse of the reagent. The reagent storage unit is housed in the main control device, so that the operation table is not filled with the reagent bottle, and the dangerous event such as the reagent bottle being reversed is prevented.

The magnetic block lock structure of the invention utilizes the principle of the same-sex attraction and the opposite sex of the magnetic block, and effectively realizes the assembly between the test device and the main control device. The magnetic block lock structure of the invention does not require the operator to use a lot of force, and does not require the operator to disassemble many screw nuts and the like, and the whole process is very simple and convenient.

The stepping motor driving gear drives the rack plate on the loading platform to drive the movement of the test paper stage, which not only improves the test speed, but also has a continuous and stable driving action of the stepping motor, and can be stable and precise. Transport the stage to the correct location.

The lower part of the stage is designed with a guide rail and a rail seat on the base, so that the stage can smoothly move in the test device, reducing noise interference.

The baffle plate of the invention not only protects the test strip carrier and the light source transmitting and receiving device in the test device, but also protects the loading platform and the light source transmitting and receiving device from external force and prevents dust pollution. At the same time, when the test device is stored separately, since the test device is a closed structure, when the test sample or test reagent remains in the test device that has been removed, the residual reagent or sample on the stage will not be exposed. Prevent pollution to the surrounding environment and operators in the external environment.

The biochemical analyzer of the present invention further includes a bracket structure for supporting the operation panel. Since the operation panel is erected and supported by the bracket, the operator panel does not collapse backward when the panel button is used.

The beneficial effects of the invention further include: 1) The biochemical analyzer of the invention adopts a plurality of modes of independent test units, which increases the number of samples tested per unit time and improves the detection efficiency. 2) The test method described in the present invention includes a plurality of determining steps, which improves the accuracy of the detection and reduces the risk of inaccurate test results caused by human error. 3) The test unit according to the present invention includes a magnetic induction starting device, which not only can effectively ensure that the test unit door is closed when starting the test, and does not need to add other unit door locking devices. Close the test unit door tightly to eliminate interference from external light sources. 4) According to the biochemical analyzer of the present invention, since the test paper loading console is installed on the instrument, the bottom surface of the test paper holding portion is not touched to the experimental desktop, so that the operator can easily pick up the test with the sample added. Test strips.

DRAWINGS

Figure 1 Schematic diagram of the biochemical analyzer;

Figure 2 Schematic diagram of the open state of the operation panel of the biochemical analyzer;

Figure 3 is a schematic view showing a state in which a test device in the biochemical analyzer is extracted;

Figure 4 shows a schematic diagram of the reagent storage unit in the biochemical analyzer;

Figure 5 is a schematic view of the rear structure of the biochemical analyzer and the test device;

Figure 6 is a second schematic diagram of the operation panel of the biochemical analyzer supported by the support;

Figure 7 Schematic diagram of the internal structure of the test device of the biochemical analyzer;

Figure 8 is a cross-sectional view of the biochemical analyzer test device along the line A-A;

Figure 9 is a schematic view showing the opening of the test device of the test device of the biochemical analyzer;

Figure 10 is a schematic view showing the first magnetic block and the second magnetic block attracting each other in the first magnetic block locking structure;

Figure 11 is a schematic view showing the first magnetic block and the second magnetic block separated from each other in the first magnetic block latching structure;

Figure 12 is a schematic view showing the structure of the second magnetic block lock;

Figure 13 is a schematic view of the third magnetic block lock structure;

Figure 14 Biochemical analyzer test flow chart.

Figure 15 is a schematic illustration of another embodiment of the biochemical analysis tester of the present invention.

Fig. 16 is a view showing the state in which the test unit door of the biochemical analysis tester shown in Fig. 15 is opened.

Figure 17 is a cross-sectional view of the biochemical analysis tester shown in Figure 15.

Figure 18 is a cross-sectional view showing the test unit in the biochemical analyzer of Figure 15.

Figure 19 is a schematic view showing the position of a magnetic induction switch and a magnetic block on the test unit door shown in Figure 16;

Fig. 20 is a view showing the hardware configuration of the biochemical analyzer shown in Fig. 15.

Figure 21 is a flow chart showing the test method of the biochemical analyzer shown in Figure 15.

detailed description

The invention will now be described in detail in conjunction with the specific drawings. These specific embodiments are merely a singular list without departing from the spirit and scope of the invention.

As shown in FIG. 1, the biochemical analyzer 1 of the present invention includes a main control device 10 and one or more independent test devices 100. The main control device 10 and the test device 100 are connected to each other through an electrical connector 140. Each test apparatus 100 can independently complete the detection items and transmit the detection results to the output of the main control unit 10 according to the instructions transmitted by the main control unit 10. Each test device 100 is designed to be in a relatively independent relationship, and the test device 100 can be freely detached from the main control device 10.

As shown in FIG. 1 to FIG. 6 , the main control device 10 includes a main power source 11 in the casing of the main control device 10 (the power is supplied to each part of the biochemical analyzer after the external commodity is powered on). The main control unit 10 also includes a main switch 12 of the analyzer, an operation panel 13, and a printer 14. The main switch 12, the operation panel 13, and the printer 14 are electrically connected to the main power source 11, respectively. The operation panel 13 is a touch display screen, which can display the interface of the detection process and the detection result, and can facilitate the operator to touch the screen for operation.

One or more storage chambers 15 of substantially the same size as the testing device 100 are disposed side by side in the casing of the main control unit 10. In order to enable the test device to be pushed into the storage chamber 15 of the main control device quickly and smoothly, at least two side walls of the storage chamber 15 are respectively designed with guide rails 16, or a guide rail 17 is designed at the bottom of the storage chamber 15, or is stored. Guide rails are designed on both sides and the bottom of the chamber. The rails cooperate with a slider or pulley (not shown) on the test device. When the test device is assembled to or detached from the main control device, the slider or pulley on the test device slides within the guide rail to guide the test device into the storage chamber of the main control device or away from the storage chamber 15.

As shown in FIG. 4, a reagent storage unit 18 having a size and shape substantially equivalent to that of the testing device 100 can be placed in the storage chamber 15, and one or more reagent storage racks 19 can be disposed in the reagent storage unit 18. It is used to store the test component for testing. The test component can be a test reagent or a reagent bucket. The advantage of this design is that the storage chamber 15 in the main control device 10 can be installed with the test device 100, or the test device 100 can be partially installed, and the other reagent storage unit 18 can be installed according to actual needs, thereby making the design more flexible. The biochemical analyzer 1 shown in FIG. 4 includes a main control device 10, two test devices 100, and a reagent storage unit 18. As a further modified embodiment, the biochemical analyzer 1 may comprise a master device 10, one to ten, even more than ten test devices 100 and one to ten, even more than ten reagent storage units 18, and test devices The number of 100 and storage unit 18 can be combined as desired. The operator can place the reagents required for the test in the reagent storage rack 19 in advance. When performing the test, the operator can conveniently take the corresponding reagent from the reagent storage unit of the analyzer. If the test device is used for a long time, the corresponding reagent storage unit can also be stored in the main control device for a long time, forming a one-to-one relationship with the test device to prevent misuse of the reagent. In addition, the reagents are placed in the reagent storage unit so that the operation surface is not filled with the reagent bottle to prevent dangerous events such as the reagent bottle being reversed.

The housing of the main control unit 10 is equipped with a USB interface 26, a fan 20, a total power inlet 21, and the like. In order to stably hold the pushed test device 100 in the storage chamber 15, the position of the back cover of the main control device corresponding to each test device may further include a lock hole 22.

The operation panel 13 may be an LCD, an LED touch screen panel, or some LCD or LED panel with buttons. The operation panel 13 is connected to the main control unit 10 via a hinge 23, and may be connected to the main control unit 10 via a hinge (not shown) and a bracket 24.

As shown in FIGS. 7-9, the test apparatus 100 includes a base 101 on which the stage 102 carrying the test strip is designed, and the light source transmitting and receiving unit 103 is located above the stage 102. A left bracket 104 and a right bracket 105 are fixedly mounted on the base 101, and the left and right brackets surround the carrier 102 therein. The light source transmitting and receiving device 103 is mounted on the left and right brackets, or the upper bracket 106 is fixedly mounted on the left and right brackets, and the light source transmitting and receiving device 103 is mounted on the upper bracket 106. The stage 102 can reciprocate in a predetermined track, and the light source transmitting and receiving device 103 can be close to and away from the stage 102. The stage 102 and the extension line of the moving or receiving path of the light source transmitting and receiving device 103 are in the same plane. The orthographic projections that intersect each other or in the same plane cross each other.

A stepper motor 107 is provided on at least one of the brackets 104 or 105, and the stepper motor is provided with gears 108. The stage 102 carrying the test strips includes a tray 110 for carrying the test strips 109. A rack plate 111 is fixedly designed on at least one side of the stage 102. The gear 108 meshes with a rack plate 111 on the stage 102. When the stepper motor is in operation, the drive gear is driven to rotate, and then the rack plate 111 is driven to run linearly, thereby feeding the stage connected to the rack plate to the test area or exiting from the test area. The accuracy of the stepping motor is relatively high. Therefore, when the gear drives the movement of the rack plate, not only the speed of transporting the test paper is improved, but also the stability and accuracy of the test are improved.

The central portion of the base 101 is fixedly designed with a rail seat 112. The rail mount 112 is used in conjunction with the guide rail 113 on the test strip carrier 102. The mount 102 can slide along the guide rail in the test device, thereby transporting the test strip to the detection. Position or exit the test area. The guide rail 113 is designed on the lower portion of the stage 102.

There is a temperature control device 114 below the test area of the test strip on the stage. When the ambient temperature of the test does not meet the preset temperature range, the temperature control device will automatically adjust the temperature (such as heating) to make the temperature of the test environment meet the preset temperature range. The temperature control device includes a resistance heating device and transfers the temperature through a ceramic sheet or a metal sheet.

A slider holder 120 may be disposed on each of the left and right sides of the test apparatus base 101, and the slider holder 120 is fixed to the base 101 by bolts. The slider 121 is fixedly designed on the slider holder 120. The slider 121 can slide freely in the guide rail 16 of the side wall of the storage chamber 15, thereby driving the entire test device to move in the storage chamber 15, and the test device is pushed into the storage chamber for preparation. The analyte is detected or removed from the storage chamber. A slider seat with a slider can also be placed in the lower portion of the base for use with the bottom rail 17 in the storage chamber. As a modified design, the slider base 120 and the slider 121 may also be a single body, or may be a strip that cooperates with the guide rail 16.

In order to better protect the test stage and the light source transmitting and receiving device, the baffles 122-126, that is, the right baffle 122, the left baffle 123, the upper baffle 124, and the front, may be respectively designed on the front and rear of the test device 100. Baffle 125 and tailgate 126. A test device door 127 is designed on the front baffle 125, and the test device door 127 and the front baffle 125 can be connected by a hinge. The test device door is closed when the test device is not in use or is being tested. When the test strip carrier in the test device needs to transport the test strip, the test device door is opened to facilitate the operator to store or take out the test paper. The baffle provides excellent protection to the test strip carrier and the light source transmitting and receiving device in the test device, so that the stage and the light source transmitting and receiving device are protected from external force and dust pollution can be prevented. At the same time, when the test device is taken out, the reagents or samples remaining on the stage will not be exposed to the external environment to prevent environmental pollution.

The light source transmitting and receiving device 103 includes an electric motor 130 (preferably a stepping motor) that pushes the light source transmitting and receiving device up and down, and the light source emitting device 131. The light source transmitting and receiving device 103 further includes an optocoupler switch 132 that controls the moving position of the light source device, the diaphragm switch 132 being electrically coupled to the electric motor 130 for controlling the operation and braking of the electric motor 130. The diaphragm switch 132 has a light-emitting aperture 133, and the light source transmitting and receiving device has a shutter 134. The shielding plate 134 has two positions of blocking the light emitting hole 133 and leaving the light emitting hole 133 with respect to the light emitting hole 133. When the light source transmitting and receiving device is running downward, when the shielding plate 134 is located above the light emitting hole 133 of the diaphragm switch 132, the light path is unblocked, the power source is always kept in the power supply state, and the light source device continues to move downward after the electric motor 130 rotates. . When the shielding plate 134 blocks the light-emitting hole 133 of the diaphragm switch 132, the optical path is cut off, thereby turning off the power of the electric motor 130, the light source device is no longer descending, and the sample detecting light source 131 is turned on to detect and analyze the sample.

Each test apparatus 100 may also include a separate microprocessor that may execute programs including, but not limited to, controlling the light source emitting device, monitoring the moving position of the tray, testing the ambient temperature, and heating the sheet, and transmitting to the outside through the data transmission interface. data.

The test apparatus 100 can also include a power interface and a data transmission interface to enable powering the test device and transmitting test results. The test device 100 can also be used with an integrated electrical connector 140. The electrical connector is a device that integrates the power interface and the data transmission interface, which allows the test device to have more space for storing other accessories, and also reduces the production process and improves the production efficiency. The test device is connected to the main control device through the electrical connector, and receives the power supply from the main control device to the test device or transmits the data to the data output device of the main control device. The electrical connector of the test device can also be connected to other data output devices.

The detection sources used on each test device can be the same or different. When the detection sources used by multiple test devices are the same, the speed and efficiency of detection can be improved. If the detection sources used in the test device are different from each other, each test device can measure the same or different biochemical parameters of the same or different samples, thereby achieving multi-purpose use. Any other combination of the master device and the test device is suitable.

In order to ensure that the test device is well fixed on the main control device, a lock structure for fixing the test device to the main control device may be provided on the test device and the main control device. The locking structure may be a fixing manner of a threaded lock (such as a bolt and a nut, a screw and a threaded hole), a snap lock or a magnetic block lock. The structure of the magnetic block lock, as shown in FIGS. 10 to 13, includes at least three magnetic blocks, a first magnetic block 151, a second magnetic block 152, and a third magnetic block 153. The first magnet block 151 is designed on the first device, and the second magnet block 152 and the third magnet block 153 are designed on the second device. The opposite faces of the first magnet block 151 and the second magnet block 152 are magnetically different (S pole and N pole, respectively), and the opposite faces of the second magnet block 152 and the third magnet 153 have the same magnetic properties (the same It is either S pole or N pole). The projections of the first magnet block 151, the second magnet block 152, and the third magnet block 153 in a direction perpendicular to their opposite faces substantially overlap. If the two devices are to be locked to each other, the first device with the first magnet 151 is pushed toward the second device with the second magnet 152, and the first device and the second device are finally magnetically attracted. Together, at this time, the third magnet block 153 is away from the second magnet block 152. If the two devices are to be separated from each other, the third magnet block 153 is pushed toward the second magnet block 152 at this time, and the mutual repulsive force between the third magnet block 153 and the second magnet block 152 and the first magnet block 151 is utilized. The magnetic attraction between the first magnet block 151 and the second magnet block 153 is weakened, thereby separating the first device and the second device from each other.

In the embodiment of the biochemical analyzer of the present invention, as shown in FIGS. 10 to 11, the first magnet block 151 is designed on the tailgate 126 of the test apparatus 100. The second magnet block 152 is fitted into the latching hole 22 of the main control unit 10. Two support frames 154 are designed on the back cover of the main control device, and the support frames 154 are respectively designed on both sides of the lock hole. The third magnet block 153 is coupled to the support frame 154 by a spring piece 155. The two faces of the first magnet block 151 and the second magnet block 152 are magnetically different (S pole and N pole, respectively), and the opposite faces of the second magnet block 152 and the third magnet block 153 are magnetically identical ( Same as S pole or N pole). Figure 10 shows a state in which the test apparatus 100 is pushed into the storage chamber 15 of the main control unit 10. At this time, the first magnet block 151 and the second magnet block 152 are attracted by the opposite sex of the magnet, and the magnetic attraction force makes The test device is firmly attracted to the main control unit without slipping out of the main control unit. As shown in FIG. 11, when the test apparatus 100 needs to be withdrawn, the third magnet block 153 is pushed in the direction of the second magnet block because the polarities of the opposite faces of the second magnet block 152 and the third magnet block 153 are the same. And the polarities of the faces of the third magnet block 153 and the first magnet block 151 are also the same. According to the principle of the same polarity of the magnet, the third magnet block 153 has both the first magnet block and the second magnet block. A repulsive action weakens the magnetic attraction between the first magnet block 151 and the second magnet block 152. With the approach of the third magnet block 153, this repulsive force substantially cancels the magnetic attraction between the first magnet block 151 and the second magnet block 152. Thereby, the test apparatus 100 can be easily extracted from the storage chamber of the main control unit.

FIG. 12 is another embodiment of a magnetic block latching structure in which a third magnet block 153 can slide over the slide bar 156. Figure 13 is another embodiment of the magnetic block latching structure. The third magnet block 153 is in contact with the spring 158 by the spring clasp 159, and the spring is in a state of being compressed and stretched by the third magnet block.

The test flow between the master device and the test device is shown in Figure 14. The workflow is as follows: first turn on the power, the biochemical analyzer is turned on and enter the power-on self-test procedure. After the power-on self-test is finished, enter the warm-up procedure. When the test temperature of the biochemical analyzer meets the preset temperature range, the detector is at Waiting for the test state, the operator selects the test device that needs to be tested. After the test strip is placed, the analyzer starts the test. After the test is finished, the test result is output, and the test strip is taken out. If you want to test the next sample, put in a new test strip again and start a new round of measurement. Shut down if all samples have been tested.

The following is another embodiment of the present invention.

As shown in Figs. 15 to 21, the biochemical analyzer 1a includes a main control unit 50a and at least two test units 100a installed in the casing 2a. A test unit door 3a is mounted on the casing corresponding to each of the test units 100a.

The main control unit 50a is connected to the total power switch, the data input/output control system, and the test unit 100a of the biochemical analysis tester 1a via data lines, wires, and the like, respectively. The data input/output includes a liquid crystal display 4a, a USB interface, a data line interface, a printer, and the like.

The test unit 100a includes a sample delivery device 110a and a test light source device 111a.

The sample delivery device 110a of the test unit 100a includes a tray 114a carrying a test strip, and a heat transfer plate 115a is disposed below the tray, through which the heat generated by the heater 116a is transferred to the detection area. The heating device 116a may be selected from electrical components such as power resistor plates. A lower pressing block heat insulating plate 117a is placed under the temperature heating device 116a to block the heat generated in the heating device and not to be transferred to other portions. The electric motor 118a is fixed to the electric motor fixing plate 119a. When the electric motor is turned on, push the plate nut to move up and down. The sample feeding device 110a sends the detection test strip to a predetermined detection position via the tray 114a, and preferably the tray 114a is controlled to reach a predetermined detection position by the photocoupler switch 121a. The photocoupler switch 121a has a light emitting hole 122a, and the tray 114a has a lower edge 123a located above the light emitting hole 122a. The lower edge 123a has two positions for blocking the light emitting hole 122a and leaving the light emitting hole 122a with respect to the light emitting hole 122a. When the lower edge 123a of the tray 114a is located above the light-emitting hole 122a of the photocoupler switch 121a, the optical path is unblocked, and the electric motor power source is always kept in the power supply state. As the electric motor 118a rotates, the tray 114a continues to move upward. After the tray 114a continues to rise and contacts the detecting light source device 112a, since the detecting light source device 112a is fixed, the tray cannot continue to advance, and the light source device generates a continuous downward pressure on the tray 114a. However, the optocoupler switch continues to move upwards under the drive of the electric motor until the lower edge 123a of the tray 114a blocks the light-emitting aperture 122a of the optocoupler switch 121a. When the illuminating hole is blocked, the optical path is cut off, thereby turning off the power of the electric motor. At this time, the test test paper has reached the detection position, and the biochemical analysis tester turns on the sample detection light source device 112a to perform sample analysis.

The test light source device 111a includes a test light source 112a and an upper press block 113a. The upper pressing block 113a is disposed in cooperation with the lower pressing plate 117a for generating a pressure on the detecting test paper. In a specific embodiment of the invention, the pressure is generally 1 kgf/cm 2-3 kgf/cm 2 , preferably 2 Kgf/cm2. The light source device has at least two functions: 1) transmitting light to a reaction area for detecting the test paper, and receiving reflected light of the reaction area. 2) transmitting light to the test area of the tray, and receiving the reflected light information, and providing the reflected light information to the system for judging whether the test paper has been placed on the test paper stage for testing.

A magnetic induction starting device for detecting the opening of the biochemical analysis tester is also provided in the test unit. The magnetic induction signal generated by the magnetic induction starting device is connected to the main control unit. In one embodiment, the magnetic induction activation device includes a magnetic induction switch 10a disposed within the test unit and a magnetic block 11a disposed on the unit door of the test unit, the material of which is selected from the group consisting of magnetic steel and magnets. When the unit door is closed, the magnetic induction switch 10a senses the magnetic field signal of the magnetic block on the unit door, and after transmitting the magnetic field signal to the main control unit, the main control unit determines the specific position of the unit door, for example, whether the unit door is closed or opened, thereby The master unit makes a judgment as to whether to initiate detection.

On the other hand, the material of the biochemical analyzer tester can be selected from materials such as iron or steel that can generate adsorption force with the magnet block, or an iron block is installed in the test unit. When the test unit door is closed, due to the magnetic force of the contact point magnet, the magnetic block mounted on the unit door can firmly suck the unit door on the casing of the main body, thereby realizing the locking of the unit door. Therefore, the biochemical analyzer does not need to add other unit door locks.

The magnetic block is fixed to the unit door by means of adhesive fixing or screw fixing. The magnet block can be enclosed within the unit door or placed outside the unit door.

A test paper loading station 5a is also mounted on the casing 2a of the analytical tester. When the sample is added, the test paper can be temporarily stored on the test paper table 5a. In one embodiment, the console is a card slot type structure, the console is composed of an upper plate 6a and a lower plate 7a, and a gap 8a is left between the upper plate and the lower plate, and the gap spacing is just a test. The thickness of the test paper is slightly larger than the thickness of the test paper. The gap of the operation table is stuck at the front end portion of the test paper, and the sample loading portion and the holding portion of the test paper are all outside the operation table, and the bottom surface of the test paper holding portion is not touched to the experimental table. This is very convenient for the operator to load and pick up the test paper. When loading the sample, the operator first chucks the test paper into the card slot of the console and then performs the sample loading. Since the pinch portion of the test paper is volley, after the sample is added, the operator can conveniently pick up the test paper to which the sample has been added, and place the test paper on the test platform of the test unit. The test paper console can be mounted below, on or above the test unit door.

In the embodiment shown in Figure 20, the biochemical analysis tester includes a master unit and three independent test units. The main control unit is connected to a power source, a printer, a display system, a USB interface, a parameter input system, and the like. The main control unit is also connected to three test units. The test unit independently completes the respective tests and transmits the test results to the main control unit, and the main control unit outputs the test results. The test unit includes a reflective photometer, a mechanical transmission, and a temperature control device.

The biochemical analysis test method as described in FIG. 21 includes:

1) Turn on the biochemical analyzer tester and set test parameters. The biochemical analysis tester includes a main control unit and at least two independent test units, and the main control unit and the analyzer power control switch, data output device, and input respectively. The control system and the test unit are connected to each other, and each test unit includes a sample delivery device 110a and a test light source device 111a.

2) Place the test paper with the sample added into one of the test units.

3) The biochemical analysis tester determines whether there is a test paper in the detection area. If not, the biochemical analysis tester gives a prompt to reposition the test paper.

4) The biochemical analysis tester determines whether the test unit door is closed. If not, the biochemical analysis tester gives a prompt to close the unit door.

5) When the test paper is already present in the detection area and the unit door is closed, both sets of information are available, and the biochemical analysis tester starts the detection and outputs the detection result.

In one embodiment, after receiving the two sets of information that the test paper already exists in the detection area and the unit door has been closed, the biochemical analysis tester also makes a judgment as to whether the detection start time exceeds a preset time. If it times out, the biochemical analysis tester gives a message to re-replace the test paper. If it does not time out, the biochemical analyzer starts to detect and output the test results.

During the test, each test unit is independently tested and does not interfere with each other, thereby improving the test speed and detecting more samples at the same time.

The biochemical analysis tester uses the light source device of the test unit to determine whether the test paper has been placed in the detection area. The test light source emits test light, and the reflected light information of the tray detection area is used to determine whether the test area has a test paper. If not, the biochemical analyzer gives the prompt to reposition the test paper.

The biochemical analysis tester uses the magnetic induction signal to determine whether the test unit door is closed. When the unit door is closed, the magnetic induction switch 10a senses the magnetic field signal of the magnetic block on the unit door, and after transmitting the magnetic field signal to the main control unit, the main control unit determines the specific position of the unit door, for example, whether it is closed or opened, thereby The control unit makes a judgment on whether to initiate detection.

The biochemical analyzer and the test method of the invention can be used for detecting a series of physiological and biochemical indexes such as glucose, cholesterol, high-density fatty acid, low-density fatty acid, triglyceride, uric acid, bilirubin, total protein, hemoglobin and ketone body. .

Claims (10)

A medical detection analyzer is characterized in that it comprises a main control device (10) and at least one test device (100), wherein the main control device (10) comprises a power supply device (11), a control device, and a detection result output device. And a storage chamber (15) not less than the number of test devices, the test device (100) includes a stage (102) for carrying the detecting element and detecting the sample, and a light source transmitting and receiving device located above the stage (102) ( 103), the testing device (100) is disposed in the storage cavity (15) of the main control device and is electrically connected with the power supply device (11) of the main control device, the control device and the detection result output device, and the control device controls the loading of the test device The stage (102) moves in a certain direction, and the light source transmitting and receiving device (103) moves toward and away from the stage in a direction substantially perpendicular to the moving direction of the stage (102), and the detection is placed on the stage (102). The color change parameter of the upper detecting element is then sent to the control device, and after being processed by the control device, the detection result is output via the detection result output device. The medical detection analyzer according to claim 1, characterized in that the test device (100) can be repeatedly withdrawn and incorporated into the main control device (10). The medical detection analyzer according to claim 2, characterized in that a slide rail structure is designed between the outer wall of the test device (100) and the inner wall of the storage chamber (15) of the main control device (10). The medical detection analyzer according to claim 3, wherein the slide rail structure comprises a guide rail (16) and a slider structure (120) disposed on an inner wall of the storage chamber (15) and an outer wall of the test device, the slider The structure (120) is slidable within the rail (16) of the storage chamber (15). A medical detection analyzer according to any one of claims 1 to 4, characterized in that it comprises two or more test devices (100), each of which can detect the same or different samples of the same type of test sample. The parameters can also detect the same or different parameters of different types of test samples. The medical detection analyzer according to claim 4, further comprising at least one reagent storage unit (18), wherein the reagent storage unit (18) can be provided with a plurality of detection elements. The medical detection analyzer according to claim 6, characterized in that the storage chamber (15) in the main control device (10) selectively houses the test device (100) or the reagent storage unit (18). A medical detection analyzer according to any of claims 1-4 and 6-7, wherein the control device comprises a touch screen display (13), the touch screen display (13) providing an operator interface. A medical detection analyzer according to any one of claims 1 to 4 and 6 to 7, further comprising a locking device for locking or releasing the main control device (10) and the testing device (100). The medical detection analyzer according to claim 9, wherein said locking device comprises three permanent magnet magnetic blocks, wherein the first and second magnetic blocks are disposed in a casing of the main control device (10), and the third The magnetic block is fixed to the outer casing of the testing device (100). When the testing device is sufficiently housed in the storage cavity (15) of the main control device, the three magnetic blocks are arranged substantially in a straight line, and the second magnetic block is located in the first and Between the third magnetic blocks, the opposite poles of the second and third magnetic blocks are opposite in magnetic polarity, and the first magnetic block and the second magnetic block are magnetically opposite to each other, and the first magnetic block can follow the test device (100) Move along the line of three magnetic blocks.

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