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WO2012015949A3 - Methods and compositions for improving yields of reduced products of photosynthetic microorganisms - Google Patents

Methods and compositions for improving yields of reduced products of photosynthetic microorganisms Download PDF

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Publication number
WO2012015949A3
WO2012015949A3 PCT/US2011/045572 US2011045572W WO2012015949A3 WO 2012015949 A3 WO2012015949 A3 WO 2012015949A3 US 2011045572 W US2011045572 W US 2011045572W WO 2012015949 A3 WO2012015949 A3 WO 2012015949A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
compositions
ethanol
photosynthetic microorganisms
reduced products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/045572
Other languages
French (fr)
Other versions
WO2012015949A2 (en
Inventor
Frank Anthony Skraly
Nikos Basil Reppas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Joule Unlimited Technologies Inc
Original Assignee
Joule Unlimited Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joule Unlimited Technologies Inc filed Critical Joule Unlimited Technologies Inc
Publication of WO2012015949A2 publication Critical patent/WO2012015949A2/en
Anticipated expiration legal-status Critical
Publication of WO2012015949A3 publication Critical patent/WO2012015949A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides methods and compositions for the improved biosynthesis of ethanol in a host cell. Genes encoding enzymes for futile cycle pathways to increase ethanol production, methods of optimizing expression of these enzymes in host cells, and methods for the production of ethanol by these host cells are disclosed. Exogenous compounds for increasing ethanol productivity by the host cells are also provided.
PCT/US2011/045572 2010-07-29 2011-07-27 Methods and compositions for improving yields of reduced products of photosynthetic microorganisms Ceased WO2012015949A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36900410P 2010-07-29 2010-07-29
US61/369,004 2010-07-29

Publications (2)

Publication Number Publication Date
WO2012015949A2 WO2012015949A2 (en) 2012-02-02
WO2012015949A3 true WO2012015949A3 (en) 2014-03-20

Family

ID=45530695

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/045572 Ceased WO2012015949A2 (en) 2010-07-29 2011-07-27 Methods and compositions for improving yields of reduced products of photosynthetic microorganisms

Country Status (1)

Country Link
WO (1) WO2012015949A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130203136A1 (en) 2011-07-27 2013-08-08 Alliance For Sustainable Energy, Llc Biological production of organic compounds
US9914947B2 (en) 2011-07-27 2018-03-13 Alliance For Sustainable Energy, Llc Biological production of organic compounds
WO2014003555A1 (en) 2012-06-27 2014-01-03 Rijksuniversiteit Groningen Improved penicillin production
US20150203824A1 (en) * 2012-07-26 2015-07-23 Joule Unlimited Technologies, Inc. Methods and compositions for the augmentation of pyruvate and acetyl-coa formation
BR112015008370B1 (en) * 2012-10-16 2022-10-18 Dsm Ip Assets B.V SACCHAROMYCES CELLS WITH IMPROVED PENTOSE CONVERSION AND PROCESS FOR PRODUCING A FERMENTATION PRODUCT
US10604773B2 (en) 2012-10-16 2020-03-31 Dsm Ip Assets B.V. Cells with improved pentose conversion
CN114426933B (en) * 2020-10-29 2023-07-04 中国石油化工股份有限公司 Method for improving yield of nitrite bacteria cells

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104390A (en) * 1988-09-01 1992-04-14 Alza Corporation Fluid receiving receptacle comprising biocide delivery system contacting outside of receptacle
US6432955B1 (en) * 1997-04-24 2002-08-13 Akzo Nobel N.V. Heterocyclic derivatives and their use as antithrombotic agents
US20080176304A1 (en) * 2006-09-25 2008-07-24 James Weifu Lee Designer Organisms for photosynthetic production of ethanol from carbon dioxide and water
US20090011406A1 (en) * 2003-08-04 2009-01-08 Kikkoman Corporation Method of Judging Fatigue
US20090155873A1 (en) * 2007-10-04 2009-06-18 Bio Architecture Lab, Inc. Biofuel production
WO2009078712A2 (en) * 2007-12-17 2009-06-25 Universiteit Van Amsterdam Light-driven co2 reduction to organic compounds to serve as fuels or as industrial half products by an autotroph containing a fermentative gene cassette
US20090221052A1 (en) * 2003-07-07 2009-09-03 Ben Hankamer Photosynthetic hydrogen production
US20100003739A1 (en) * 2008-02-08 2010-01-07 Ulf Duhring Selection of ADH In Genetically Modified Cyanobacteria For The Production Of Ethanol
US20100143997A1 (en) * 2008-10-31 2010-06-10 Thomas Buelter Engineered microorganisms capable of producing target compounds under anaerobic conditions

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5104390A (en) * 1988-09-01 1992-04-14 Alza Corporation Fluid receiving receptacle comprising biocide delivery system contacting outside of receptacle
US6432955B1 (en) * 1997-04-24 2002-08-13 Akzo Nobel N.V. Heterocyclic derivatives and their use as antithrombotic agents
US20090221052A1 (en) * 2003-07-07 2009-09-03 Ben Hankamer Photosynthetic hydrogen production
US20090011406A1 (en) * 2003-08-04 2009-01-08 Kikkoman Corporation Method of Judging Fatigue
US20080176304A1 (en) * 2006-09-25 2008-07-24 James Weifu Lee Designer Organisms for photosynthetic production of ethanol from carbon dioxide and water
US20090155873A1 (en) * 2007-10-04 2009-06-18 Bio Architecture Lab, Inc. Biofuel production
WO2009078712A2 (en) * 2007-12-17 2009-06-25 Universiteit Van Amsterdam Light-driven co2 reduction to organic compounds to serve as fuels or as industrial half products by an autotroph containing a fermentative gene cassette
US20100003739A1 (en) * 2008-02-08 2010-01-07 Ulf Duhring Selection of ADH In Genetically Modified Cyanobacteria For The Production Of Ethanol
US20100143997A1 (en) * 2008-10-31 2010-06-10 Thomas Buelter Engineered microorganisms capable of producing target compounds under anaerobic conditions

Also Published As

Publication number Publication date
WO2012015949A2 (en) 2012-02-02

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