WO2012007163A1 - Retrievable wire stent - Google Patents

Abstract

The invention relates to a medical device for inserting into a hollow body organ, comprising a hollow body (10) made of a netting (11) of wire elements (12) that intersect each other in order to form meshes (13), said netting (11) having a terminating edge (14) that bounds an axial end (15) of the hollow body (10). The invention is characterized in that the terminating edge (14) is disposed in a continuously peripheral manner in the circumferential direction of the hollow body (10) and is formed by a first end loop (16a), and said first end loop (16a) - is disposed diagonally with respect to the longitudinal axis of the hollow body (10) such that the first end loop (16a) forms a tip, - comprises at least one wire element (12) of the netting (11), said wire element extending along the circumference of the terminating edge (14) in a continuous manner at least to the tip of the first end loop (16a), and - is free from the meshes (13) of the netting (11) at least in some sections, in particular on the entire circumference of the terminating edge (14). At least one second end loop (16b, 16c, 16d) is arranged in an inwardly offset manner in the direction of the longitudinal axis of the hollow body (10) and in a spaced manner with respect to the first end loop (16a), and the second end loop (16b, 16c, 16d) - extends along the first end loop (16a) at least in some sections and forms a tip, and - comprises at least one wire element (12) of the netting (11), said wire element extending continuously at least to the tip of the second end loop (16b, 16c, 16d). The first and second end loops (16a, 16b, 16c, 16d) are connected to each other in an elastic and/or flexible manner such that said end loops (16a, 16b, 16c, 16d) can be moved relative to each other in the longitudinal direction of the hollow body (10).

Description

 RETRACTABLE WIRE TENT

description

The invention relates to a medical device for introduction into a hollow organ and to a method for producing such a device. A generic device with the features of the preamble of claim 1 is known for example from DE 101 27 602 AI.

For the treatment of aneurysms, stenoses and for the expansion of thrombi lattice structures are suitable, which have an increased Feinmaschigkeit. By means of the fine mesh, the flow conditions in the aneurysm can be influenced, in particular by a slowing of the flow in the aneurysm

Aneurysm with the purpose of causing coagulation and sclerotherapy of the aneurysm. The fine-meshed lattice structure also promotes the rapid growth of cells (endothelialization). In the expansion of stenoses and thrombi particles are also well blocked by the fine mesh.

An increased Feinmaschigkeit is achieved for example by braids, which are therefore particularly well suited for this type of use.

Braids are also needed in the endovascular area whenever increased flexibility is required. For example, baskets can be made to protect against distal embolism or to remove thrombus in the form of braids. Due to the good flexibility of braids, the treatment is also possible in very tortuous areas, such as in the brain area. Baskets can also be used in other areas, such as the bladder for removing stones. Flexibility is also beneficial in the context of treating aneurysms or stenoses when they are located at highly tortuous vascular sites. It is known to make braids with an open structure. This means that the wires of the braid have free ends. As a result, the wires can be braided as a long strand, which is then cut to the appropriate length. This results in different units, each with open or free wire ends. This production technique is suitable when the mesh has many wires and the custom-made individual units is uneconomical. Braids with a large number of wires are very fine-meshed and have the advantages mentioned above.

Alternatively braids can be made with closed loops. This requires a single production of each braid. The braids produced in this way have the advantage that the braid ends rounded by the loops have an atraumatic effect and reduce the risk of injury to the vessel wall.

An example of a braid with closed loops is disclosed in the aforementioned DE 101 27 602 AI. The document describes a stent for implantation in the human body with a hollow cylindrical body made of a braid. At the braid ends, the free ends of the wires of the braid are brought together and connected such that loops are formed at the braid ends. The loops at the braid ends lead to a terminal edge of the mesh with a serrated contour.

Both braids, in which the wires free ends as well as braids with closed loops on the braid ends, as described for example in DE 101 27 602 AI, have the disadvantage that the free wire ends or loops hinder the retraction of the braid in a catheter or even completely prevent it after it has been released from the catheter into the vessel. Moreover, in the case of braided wire ends at the braid end, in view of the recoverability of the braid, there is a problem that a guide wire for retraction can not be practically connected to the braid. Even if the braid were connected at one point to a guidewire that draws the braid into the catheter, the free wires at the catheter opening would tilt. This would damage the braid and catheter. Retraction of the mesh is therefore not possible. Even a braid that ends with closed loops, can not retract into the catheter after it has been completely discharged. Such a braid has several corners at the end of the braid, which tilt when pulled into the catheter. This is especially the case when the braid is connected to a guidewire at a single location.

The invention has for its object to provide a medical device for import into a hollow body organ comprising a mesh whose end edge is designed so that the device can be withdrawn into a delivery system, for example in a catheter after the device completely or partially from the Feeding system was dismissed.

According to the invention the object is achieved by the device according to claim 1.

The invention is based on the idea of providing a medical device for insertion into a hollow body organ with a hollow body made of a mesh of wire elements, which intersect to form meshes, wherein the braid has a terminal edge which defines an axial end of the hollow body. The

The end edge is formed continuously circumferentially in the circumferential direction of the hollow body and formed by a first end loop. The first end loop is inclined relative to the longitudinal axis of the hollow body, such that the first end loop forms a tip. The first end loop comprises at least one wire element of the braid, wherein the wire element extends continuously along the circumference of the end edge at least to the tip of the first end loop. The first end loop is at least partially, in particular on the entire circumference of the end edge, free from the mesh of the braid , At least one second end loop is offset inwardly in the direction of the longitudinal axis of the hollow body and spaced from the first end loop. The second end loop extends at least in sections along the first end loop and forms a point. The first end loop comprises at least one wire element of the

Braid, wherein the wire element extends continuously at least to the tip of the second end loop. The first and second end loops are elastically and / or flexibly connected to each other such that the end loops are movable relative to one another in the longitudinal direction of the hollow body. The invention has the advantage that a continuous peripheral edge is formed by the formation of the end edge through the end loop, which can be withdrawn with only a small resistance in the feed system. in the

In contrast to known braids having a serrated and thus discontinuous terminal edge, the recoverability of the device according to the invention is improved or even made possible in the first place. In contrast to braids, in which the terminal edge is formed of stitches, which lead to a thickening at the edge region, according to the invention a relatively thin

Reached the end edge, which can be well fed into the feed system. This is inventively achieved in that the end edge is formed by an end loop, which is free of mesh at least in sections. The end edge is thus at least partially formed only by the first end loop and is decoupled in this area from the mesh of the mesh.

The first end loop comprises at least one wire element of the braid, wherein the wire element extends continuously along the circumference of the end edge at least to the tip of the first end loop. This can be the end loop

at least a single continuous wire element for a closed loop or at least two separate wire elements for an open loop, which extend on both sides of the median plane of the hollow body and meet in the top of the end loop. It is also possible to form the end loops by a plurality of wire elements forming a wire strand. The wire strand can be completely continuous (closed loop) or split in the top (open loop). This applies to the first end loop which forms the terminal edge and / or to the second inwardly offset end loop. The terminal edge formed from a loop leads to a relatively smaller crimp diameter compared to a terminal edge, which is formed from individual stitches, since it does not overlap the two bevels (on both sides of the median plane of the hollow body) of several mesh wires during crimping ,

The at least one second end loop is in the direction of the longitudinal axis of

Hollow body offset inwardly and spaced from the first end loop arranged. The second end loop extends at least in sections along the first end loop and forms a point. The second end loop essentially follows the course of the first end loop, wherein the loops can run parallel or non-parallel. The first and second end loops are substantially in the same Direction and are spaced from each other. Thus, the second end loop at least partially on a similar or the same geometry as the first end loop on.

The second end loop comprises at least one wire element of the braid, wherein the wire element extends continuously at least to the tip of the second end loop. In this respect, the second end loop is constructed like the first end loop. Reference is made to the comments on the construction of the first end loop. The

Possibilities of the wire element assemblies disclosed in connection with the first end loop (eg, single wire / stranded wire and / or open / closed loop) may be realized differently in the first and second end loops, respectively.

The first and second end loops are elastically and / or flexibly connected to each other such that the end loops are movable relative to one another in the longitudinal direction of the hollow body. This achieves two things: First, the

Increases the stability of the end loops in the area of the end edge, which improves the security when retracting the braid. The risk of tilting of the end loops is reduced and the guidance or guidance of the braid on re-entry is improved. On the other hand it comes with

Pull back to a compression of the mesh, which should be as distortion-free as possible. By the elastic and / or flexible connection of the end loops and the associated approval of the relative movement of the end loops in

Longitudinal direction of the hollow body is achieved that the distance between the end loops during deformation, so when the hollow body is retracted into the feed system, can change. This causes the at least partially

Decoupling of the end loops of the stitches of the braid remains, even if the end loops for stability reasons are at least selectively connected to each other.

In a preferred embodiment of the invention, the end loops are connected by an elongated connecting element whose main orientation extends in the longitudinal direction of the hollow body. The connecting element allows a simple and effective coupling, in particular selective coupling, the end loops. By the course of the main orientation of the connecting element in the longitudinal direction of the

Hollow body is achieved, that the connecting element or a longitudinal axis of Connecting element is arranged in the feed direction, in which the hollow body is moved during retraction into the feed system. By this orientation, a favorable power transmission is achieved when pulling into the feed system. It is sufficient if the main orientation of the connecting element extends in the longitudinal direction of the hollow body. This includes the possibility that the elongated

Connecting element is straight and extends parallel to the longitudinal direction of the hollow body. The longitudinal main orientation also includes the possibility that the connecting element is partially separated from the

Deviates longitudinal direction of the hollow body, provided that the longitudinal extent of the

Total connecting element extends in the longitudinal direction of the hollow body, such as in an S-shaped connecting element. It may be sufficient if the end points of the connection between the end loops, in particular between adjacent end loops, in particular between all end loops, lie on an imaginary line which runs parallel to the longitudinal axis of the hollow body. The connection points can be with the tips of the

End loops coincide. The tips of the end loops can be arranged on an imaginary line which runs parallel to the longitudinal axis of the hollow body.

In a further preferred embodiment, the connecting element is flexible in the longitudinal direction of the hollow body. This ensures that at a

Deformation of the end loops, especially with different degrees of deformation of the various end loops, a change in distance between the end loops can take place without distorting the mesh of the mesh by the deformation of the end loops. Due to the flexibility of the connecting element, the relative movement between the end loops during deformation is made possible.

The connecting element preferably comprises at least one connecting wire, which is in each case curved between the end loops such that the

Boundary wire extending in relation to the longitudinal axis of the hollow body sections in different, in particular deviating from the longitudinal axis directions. In a deformation of the end loops when pulling the hollow body in the feed system increases the distance between end loops. The flexibility of the connecting element, or the connecting wire is in this

Embodiment achieved in that the curved in the initial state connecting wire stretches in the deformation of the end loops, so that the distance between the end loops can change. In the case of a plurality of end loops, the connecting wire can in each case be curved between all end loops, so that it is possible for the change in length of the connecting wire corresponding to the change in distance between all end loops to be enabled by a sectionwise stretching of the connecting wire between the end loops. The curvature of the connecting wire between each end loop is not mandatory. For example, individual end loops can be skipped by the connection wire. Multiple bends in different directions between adjacent end loops are also possible.

The connecting wire can be singly or multiply S-shaped, for example

be educated. In a simple S-shaped design, the connecting wire has two opposing curvatures. In a multiple S-shaped design of the connecting wire has this three curvature, four curvature or more than four curvatures. Overall, the number of bends corresponds to the

Connecting wire at least the number of end loops, which by the

Connecting wire are connected. For multiple bends in different directions between adjacent end loops, the total number of

Curvatures greater than the number of end loops provided, none

End loop is skipped.

The connecting wire may extend in sections in the same direction of the wire elements of the staggered end loops. This increases the stability of the terminal edge and the area of the free end loops adjoining the terminal edge.

In a further preferred embodiment, the connecting wire

Openings in which the wire elements of the end loops are arranged. This embodiment is particularly well suited for closed end loops, which are formed from at least one continuous wire element. Thereby, a simple production of the braid by threading the end loops is made possible in the openings of the connecting wire, wherein the threading can be done in a preliminary step before the actual braid production.

The connecting wire can be cohesively, non-positively or positively connected to the wire elements of the end loops. An example of the frictional Connection are Crimphülsen, both open and closed

Loops are suitable. The connection between the connecting wire and the wire elements may alternatively be done by welding, gluing or form-fitting by twisting.

In a further embodiment, the end loops form closed loops, each with at least one continuous wire element, which has two sections with axial components which are opposite in the course of the wire and extend in the longitudinal direction of the hollow body. The bonding wire is connected to a first portion of an end loop and a second portion of the next end loop, wherein the first portion of the one end loop and the second portion of the next end loop have opposing axial components. This embodiment forms a concrete example of the coupling of several closed loops by a connecting wire. The orientation of the connecting wire with differently oriented sections of the mutually downstream end loops on the one hand increases the stability of the loop arrangement in the region of the end edge. On the other hand, by the resulting course of the

Connecting wire reaches the flexibility of the connection or coupling of the loops. The connection of the connecting wire with the individual end loops has the advantage that when pulling the braid into the feed system, the tensile force is distributed to the individual end loops, as this in each case to the individual

End loops attacks. Due to the flexibility of the connecting wire is the

Distance change between loops during deformation compensated.

In a further preferred embodiment, the end loops form open loops each having at least two separate wire elements, of which one wire element has two sections with opposite paths in the wire

Having circumferential components which extend in the circumferential direction of the hollow body. The connecting wire is connected to a first portion of an end loop and a second portion of the next end loop, wherein the first portion of the one end loop and the second portion of the next end loop

have opposite circumferential components. Through the connection of the

Connecting wire with different sections following each other

End loops, the connecting wire is aligned according to these differently oriented sections, which on the one hand, the stability of

Loop arrangement is increased in the region of the end edge and on the other hand, the Flexibility of the connecting wire due to the different sections and thus different from the longitudinal axis of the hollow body alternately

Alignment of the wire is achieved. The alignment can be coaxial or parallel. This is not mandatory. The merged wires may have at least partially aligned in different directions axes.

In the above embodiments, the connecting element is formed as a separate additional element which cooperates with the wire elements of the braid.

In contrast, in the following embodiment, the connecting member is formed by the wire members of the braid and not by a separate member in addition to the braid members. In this embodiment, the end loops form open loops, each with at least two separate ones

Wire elements, of which a wire element has two sections with opposite in the wire path circumferential components which extend in the circumferential direction of the hollow body. The connecting element is through the separate

Formed wire elements of the end loops, wherein at least one wire element of the one end loop and at least one wire element of the next end loop are brought together. The winding direction of the merged wire elements changes such that the wire elements on the one hand in the direction of a first

Section of an end loop and on the other hand are arranged in the direction of a second portion of the next end loop. The first section of one end loop and the second section of the next end loop have opposite directions

Perimeter components.

In principle, the present embodiment is constructed similarly to the above-mentioned embodiments, since the connecting element in the form of the separate wire elements of the end loops is adapted to the course of the end loops, in particular the course of the first section of an end loop and the second section of a next end loop. This will be a

in sections of the longitudinal extent or longitudinal axis of the hollow body deviating shape of the connecting element or the merged

achieved separate wire elements, which causes the flexibility of the connecting element. On the other hand, the individual end loops through the merged wire elements coupled, so that the stability is increased or avoidance of the end loops when pulling into a feed system is avoided. The formation of the connecting element in the form of the separate wire elements of the end loops has the advantage that no additional element is used, whereby a particularly flat structure in the region of the end edge is achieved, which has a positive effect on the crimpability and the flow conditions in the vessel after implantation influenced as little as possible.

The wire elements of the one end loop can be connected to the wire elements of the next end loop and form a connection point, the wire elements of the next end loop after the connection end such that the number of wire elements in the longitudinal direction of the hollow body remains constant. This means that the wire elements of the next respective end loop are cut off after the connection point or otherwise shortened. Due to the consequent constant number of wire elements in the longitudinal direction of the hollow body, a substantially constant flexibility of the connecting element is achieved.

In another embodiment, the wire elements of the one end loop may be fed to the wire elements of the next end loop such that the number of merged wire elements increases in the longitudinal direction of the hollow body. Specifically, the number of wire elements increases with each other end loop such that the number of wire elements in the region of the end edge is maximum. This embodiment has the advantage of easy manufacture. Moreover, the stability of the hollow body is increased in the region of the end edge.

The above-mentioned embodiments are generally based on the idea of making the connecting element flexible in the longitudinal direction, in order to change the distance between the end loops when drawing into the braid, in particular the

To compensate for the increase in the distance between the end loops. This is done in the above-mentioned embodiments by the geometry of the connecting element, in particular of the connecting wire. Alternatively or additionally, it is possible to form the connecting element elastically, i. to choose the material properties of the connecting element so that the

Connecting element elastically deformed or elastically elongated when subjected to a tensile force in the longitudinal direction of the hollow body. The geometric condition

Flexibility can with the elastic material of the connecting element or the Combined wire. A purely geometric flexibility due to non-stretchable connecting element is just as possible as an elastic

Connecting element without additional geometric flexibility.

Alternatively or in addition to the flexible design of the connecting element is provided in a further embodiment that the connecting element and at least one end loop are slidably connected in the longitudinal direction of the hollow body. Thus, the length compensation in the change in distance of the end loops is effected by a relative movement between the end loop and the

Connecting element. The connecting element remains fixed relative to the hollow body when pulled into the feed system and the end loops or the

at least one end loop slide in the longitudinal direction of the hollow body on the

Connecting element. Thus, different distances can be set between the different end loops, without this leading to distortion of the

Grid mesh leads.

In a preferred embodiment, the connecting element may comprise at least one connecting wire, which is connected to the end loops respectively by a

Lubricant, in particular slidably connected by sleeves and / or coils. The connection between the connecting wire and the end loops by a lubricant on the one hand allows the radial fixation of the end loops, which are supported in the radial direction on the connecting wire and on the other hand a

Relative movement in the longitudinal direction of the hollow body by the sliding displacement.

The connecting wire preferably has at least one stop, which cooperates with a lubricant by an axial movement of the connecting wire relative to the end loop and acts on the hollow body with a tensile force. As a result, the adhesion between the guide wire or generally between the actuating means, by the fact that the hollow body in the

Feeding system is fed, and hulled the hollow body.

The connecting means may comprise a lubricant fixed on the one hand firmly to the first end loop which forms the terminal edge, and on the other hand slidably displaceable with the separate wire elements of the at least one second open loop

End loop is connected. The separate wire elements are brought together in the longitudinal direction of the hollow body, wherein the free end arranged in the lubricant are. The lubricant associated with the first end loop may be connected to the guide wire or other actuating means. The

merged wire elements whose free ends are arranged in the lubricant, are based on Gleitm ittel in the radial direction, so that a tilting of the

Device during insertion into the feed system is avoided.

The invention will be explained below with reference to embodiments with reference to the accompanying schematic drawings with further details. These show the development of a wire mesh with closed end loops according to an inventive

 Embodiment, by a spring element

 are connected; the settlement of a wire mesh with closed end loops according to an inventive

 Embodiments connected by an alternately curved connecting wire; the settlement of a wire mesh with closed end loops according to an inventive

 Embodiment by an alternating

 curved connecting wire are connected by means of sleeves;

Figure 4: the settlement of a wire mesh with open

 End loops according to an inventive

 Embodiment by an alternating

 curved connecting wire are connected by means of sleeves;

Figure 5: the settlement of a wire mesh with open

 End loops according to an inventive

Embodiment, by the separate Wire elements of the end loops are connected to each other;

Figure 6: the Abwickl tion of a wire mesh with open

 End loops according to an embodiment of the invention, wherein the end loops are connected by the separate wire elements in a variant of the embodiment of Figure 5;

Figure 7: the settlement of a wire mesh with open

 End loops according to an embodiment of the invention, which are slidably connected to a connecting wire;

Figure 8: the settlement of a wire mesh with open

 End loops according to an embodiment of the invention, the sliding with the

 Bonding wire are connected, having stops;

Figure 9: the settlement of a wire mesh with open

 End loops according to an embodiment of the invention, wherein the first end loop is connected to a sleeve in which the separate wire elements of the remaining end loops are slidably mounted;

Figure 10 is a view of a mesh;

Figure I Ia to

 Figure ld views of various loop shapes;

Figure 12 is a partial view of a mesh of alternative form;

Figure 13 shows the settlement of a wire mesh with partially

stitch-free end loop according to an embodiment of the invention, in which the end loops are connected by a curved Verbindu ngsdraht; Figure 14 shows the settlement of a wire mesh with partially

 mesh-free end loop according to an embodiment of the invention, in which the end loops are connected by a spring element

Figure 15 shows the settlement of a wire mesh with partially

 stitch-free end loop according to an embodiment of the invention, wherein the mesh-free portion is arranged in the region of the tip; and

Figure 16 shows the settlement of a wire mesh with partially

 stitch-free end loop according to an embodiment of the invention, wherein the mesh-free portion is arranged in the region on both sides of the tip.

FIG. 1 shows an exemplary embodiment of the medical device according to the invention

Device for importing r presented in a hollow body organ. The medical

Device may comprise a cylindrical hollow body 10. Other

rotationally symmetrical shapes of the hollow body are possible whose diameter is variable, in particular compressible and expandable. The medical device is for example a stent. The medical device may also be a thrombectomy device, such as a thrombus removal basket. The device may comprise a recanalization device. Other medical devices for vascular applications, such as filters, are provided by a delivery system, such as a catheter, inserted into a

Body hollow organ dismissed and returned from the dismissed state in the

Feed system to be withdrawn.

The device can be converted to a compressed state and to an expanded state. In the compressed state, the device is arranged longitudinally displaceable in the catheter and expands after discharge from the catheter in a conventional manner. The device can be self-expanding or through

Exposure of an external force expand, for example. By a Bal lon. The device comprises a hollow body 10 made of a braid 11 made of wire elements 12. The hollow body is shown in Figure 1 in unwound representation and has a rotationally symmetrical, in particular a cylindrical shape. The hollow body 10 is closed in the circumferential direction. The mesh 11 is off

Wire elements 12 produced in a conventional manner by a braiding process. The wire elements 12 are intertwined and cross over to form stitches 13. The formation of the mesh 13 takes place in a conventional manner. The braid 11 has a terminal edge 14 which limits an axial end 15 of the hollow body 10. The axial end 15 of the hollow body 10 corresponds to the proximal end of the hollow body 10, that is closer to the user arranged end of the hollow body 10, which (not shown) when retracting the device in the feed system first enters the feed system. The oppositely disposed distal end of the hollow body 10 is not shown. The wire ends, especially the free ones

Wire ends of the braid 10 may be fixed at the distal end in a conventional manner. It is also possible to arrange the free ends of the wire elements 12 at the distal end as in DE 10 2009 006 180.0, which is based on the Applicant. The content of this application is incorporated by reference in its entirety.

The provided at the proximal end 15 of the hollow body 10 end edge 14 is arranged continuously circumferentially in the circumferential direction of the hollow body. The final edge 14 thus forms a smooth continuous edge in contrast to the serrated edge according to DE 101 27 602 AI. The end edge 10 is arranged obliquely relative to the longitudinal axis of the hollow body. This results in FIG. 1 from the arrow-shaped tip 31 of the unwound representation, which forms the oblique end edge 14 in the spatial form of the hollow body 10. The hollow body 10 has a single tip 31. The tip 31 forms in the proximal longitudinal direction of the

Hollow body furthest projecting element of the hollow body.

The final edge 14 extends in the spatial shape of the hollow body 10 along an inclined plane, which at an angle not equal to 90 ° with respect to the

Longitudinal axis of the hollow body is arranged. It may be a straight or curved, in particular a convex or concave curved plane in which the end edge 14 is located. The oblique end edge 14 may thus be straight or concave or convex. The end edge 14 is formed symmetrically with respect to the central axis of the hollow body. As shown in Figure 1, the end edge 14 is formed by a first end loop 16a. In contrast to the mesh 13 of the mesh 11, a parent unit of the mesh 11 is understood in the context of the application under a loop. A mesh 13 is delimited by wire elements which extend both inwardly into the mesh, ie from the proximal end in the direction of the distal end, as well as by wire elements which are outwardly, ie from the distal end to

proximal end. In contrast, loops are larger units than meshes that are longer than the meshes only by outwardly extending wire elements, ie, wire elements extending from the distal end to the mesh

be limited proximal end. In this area, loops have no inwardly extending wire elements, so no wire elements, which extend from the proximal end to the distal end.

To clarify the difference between stitches and loops according to the present application, reference is made to FIGS. 10 to 12. As can be seen in FIG. 10, a grid cell is referred to as a mesh, the wires of which overlap in all corners of the cell and have different directions. In contrast, a loop is a grid cell in which the wires do not cross at a corner and change direction. This corner is called the top of the loop. There are various possibilities for this. In a closed loop, which consists of a single continuous wire or a single continuous strand of wire of several individual wires, the wire in the region of the tip makes a change in direction (Fig. IIa). In an open loop, which consists of at least two separate wires or strands of several individual wires, the wires meet in the top of the loop and make one

Direction change so that the wires are continued after the tip in the same direction. The direction of the continued wires can with a

Direction change of the wires to be connected in front of the tip (Fig. IIb). Alternatively, the wires may extend past the tip in the same direction as one of the wires or wire strands in front of the tip. Thus, only the other wire or the other strand of wire undergoes a change in direction to the tip (Fig lld). The other corners of the loop may be formed by crossovers such as stitches (Figure 11c). Fig. IIa, IIb, 11c, lld thus each show loops. In contrast, a variant of a mesh is shown in Fig. 12, in which the wires cross in the tip. The end edge 14 according to FIG. 1 is formed by the first end loop 16a, which comprises at least one wire element of the braid. It is possible that the

End edge 14 is formed by a single wire element 12 of the braid 11 or by a plurality of wire elements 12 of the braid 11. In this case, the end loop 16a, a closed end loop, as shown in Figures 1-3 or an open

End loop, as shown in Figures 4-9, include. The closed

End loops comprises one or more continuous wire elements 12 whose axial component changes in the course of the wire. Open end loops are formed from at least two separate, ie non-continuous wire elements 12a, 12b with free ends, whose axial components are arranged in opposite directions relative to the same wire path. Again, it is possible in each case to combine a plurality of wire elements 12a, 12b to form a wire strand.

The end edge 14 is formed by a single end loop 16a, namely the first end loop 16a. The single end loop 16 forms the outer one

Limitation of the mesh. The end loop 16a forms a single tip 31. The first end loop 16a is decoupled from the mesh 13 of the mesh 11. The first end loop 16a thus runs free of the stitches 13 and is connected to the braid 11 in that the first end loop 16a is formed by a wire element 12 which is part of the braid or comes out of the mesh part of the braid 11. This is shown in Fig. 1 and in the others

Unwinds thereby clarifies that the coming of the braid 11 left wire 16a 'is not drawn all the way to the end loop 16a. In the three-dimensional state of the hollow body 10, the left wire 16a 'merges into the right-hand part of the end loop 16a shown in FIG. The same applies to the right wire 16a ", which merges into the left part of the end loop 16a, this applies to all

Embodiments.

The first end loop 16a is not directly connected to the stitches 13 of the mesh 11 in the region of the end edge 14 and thus decoupled from them. In contrast to the unpublished DE 10 2009 056 450, which is based on the

Applicant goes back, the first end loop 16a is not connected to other loops, the first end loop 16a with the mesh-shaped part of

Pair mesh 11. Between the first and the second end loop 16a, 16b or generally between adjacent end loops there is at least one wire-free section without connection between the end loops 16a, 16b. The wireless Section is longer than a loop or a loop of the mesh. In particular, the wireless section is at least the length of two stitches or

Loops. A gap is formed between the end loops, which is seen in the wire longitudinal direction is greater than a mesh or loop of the braid. The mesh decoupled portion extends along the entire circumference of the terminal edge 14. It is also possible for the mesh free portion to extend only over a partial perimeter of the terminal edge (Figures 13-17).

The hollow body 10 has further, in particular three further end loops 16b, 16c, 16d, which are offset in each case inwardly offset from the first end loop 16a or inwardly offset from the respectively adjacent adjacent end loop 16b, 16c, 16d. The further end loops 16b, 16c, 16d are each spaced from the first end loop 16a or from the respective upstream adjacent end loop 16b, 16c, 16d and staggered in each case in the direction of the distal end of the hollow body 10. Between the individual end loops 16a, 16b, 16c, a distance is provided. This distance is variable during compression of the hollow body 10. Concretely, the distance between the individual end loops 16a, 16b, 16c during compression is increased in each case. When expanding the hollow body 10, the distance is reduced starting from the compressed state. The change in the distance between the end loops corresponds to each.

The arrangement of the other end loops 16b, 16c, 16d corresponds in principle to the arrangement and the course of the first end loop 16a. The further end loops 16b, 16c, in particular the second and third end loops 16b, 16c are freely arranged such that they are decoupled from the loops 13 of the braid 11. The innermost end loop 16d, in particular the fourth end loop 16d is the smallest of the end loops 16a, 16b, 16c, 16d and has the size of a stitch. Since the innermost end loop 16d is directly adjacent to the mesh 11, there is no or at least a lesser degree of decoupling. In contrast to the first end loop 16a, which forms the outer edge or the end edge 14 of the braid 11, the further end loops 16b, 16c, 16d are arranged in the interior of the braid. The length of the further end loops 16b, 16c, 16d is shorter than the length of the first end loop 16a. The length of the end loops 16a, 16b, 16c, 16d decreases with increasing distance from the proximal end of the hollow body. The end loops 16a, 16b, 16c, 16d are in the axial and circumferential directions

spaced apart. The end loops 16a, 16b, 16c, 16d do not directly contact each other. In particular, the end loops 16a, 16b, 16c, 16d do not intermesh, but extend independently of one another.

The first end loop 16a is spaced from the second end loop 16b, 16c, 16d over the entire circumference of the hollow body 10 and the terminal edge 14, respectively. In particular, the first end loop 16a and the second end loop 16b, 16c, 16d are arranged without crossover. In other words, there is a gap between the first end loop 16a and the second end loop 16b, 16c, 16d so that the end loops 16a, 16b, 16c, 16d do not touch each other or intersect. Preferably, the first and second end loops 16a, 16b, 16c, 16d extend parallel to one another over the entire circumference of the terminating edge 14 or the hollow body 10.

The first and second end loops 16a, 16b, 16c, 16d are each formed from a wire element 12, which continues in the braid 11 continuously. The wire element 12 is thus intertwined with several other wire elements 12 to the braid 11 and forms in the course of a first and / or second end loop 16a, 16b, 16c, 16d. Preferably, the first and second end loops 16a, 16b, 16c, 16d are each formed of wire elements 12 disposed within the braid 11 parallel to each other. Two in the mesh 11 parallel to each other and immediately adjacent arranged wire elements 12,

In particular, wire elements 12, which have the same winding direction in the braid 11, continue beyond the braid 11 and form respectively the first and second end loops 16a, 16b. The wire elements 12 of the first and second end loops 16a, 16b, 16c, 16d therefore belong to the mesh 11, wherein at least the first end loop 16a protrudes at least in sections beyond the hollow cylindrical basic shape of the hollow body 10. The preceding section of the first

End loop 16a forms the end edge 14.

The trailing edge 14 is smooth. In particular, the end edge 14 forms over the entire circumference of the hollow body 10 smooth edge. The entire end edge 14 is formed only by the wire member 12 of the first end loop 16a. The wire element 12 of the first end loop 16a extends along the circumference of the hollow body 10. The wire element 12 of the first end loop 16a and the first The final edge 14 thus forms a final element for the hollow body 10. In other words, the hollow body 10, in particular the braid 11, no further elements that protrude beyond the smooth end edge 14. The end edge 10 may have a substantially circular or elliptical contour. In general, the end edge 14 has a steady course.

The end loops 16a, 16b, 16c, 16d are arranged in parallel. Due to the parallelism of the end loops 16a, 16b, 16c, 16d, it is achieved that the end loops 16b, 16c, 16d offset inwardly follow the course of the terminating edge until the draw-in region 25 merges into the mesh-shaped part 26 of the braid 11. Another geometric arrangement of the end loops 16a, 16b, 16c, 16d is possible. The further end loops 16b, 16c, 16d may follow the course of the first end loops 16a and may be arranged non-parallel. For example. the distance between two adjacent end loops 16a, 16b, 16c, 16d in the region of the tips can be smaller or larger than in the region close to the braid, or at the transition from the

End loop to be braid. The end loops 16b, 16c, 16d essentially follow the course of the first end loop 16a in that they extend in substantially the same direction.

In general, the tips of the end loops 16a, 16b, 16c, 16d are arranged on a common imaginary line which runs parallel to the longitudinal axis of the hollow body 10.

The inwardly staggered end loops 16b, 16c, 16d are located in the region of the end edge 14 and, together with the first end loop 16a, form the catchment area 25 of the hollow body 10, which acts as the first braid part in the end

Feeding system or the catheter is withdrawn. By appropriate training of the end loops 16 a, 16 b, 16 c, 16 d can be the entire

Catchment area 25 crimp well. In addition, the production is facilitated.

In principle, it is conceivable to realize the draw-in region 25 of the hollow body 10 by means of a single end loop 16a, which simultaneously forms the closing edge 14, the stitches 13 of the mesh 11 engaging the sole end loop 16a

connect without being connected to this along the end edge 14. The formation of the catchment area 25 by several staggered arranged End loops 16a, 16b, 16c, 16d has the advantage that the proximal end of the hollow body is stable and easily retractable.

In the embodiment according to FIG. 1, the catchment area 25 has four

End loops 16a, 16b, 16c, 16d. It is also possible to form the catchment area 25 with two or three end loops or with more than four end loops.

For example, the catchment area 25 may comprise five end loops, six end loops or more than six end loops which are staggered in each case, that is to say offset towards the distal end.

The catchment area 25 is the foremost area of the proximal direction

Hollow body 10, the first when retracting the hollow body 10 in a

Feeding system is moved.

The above-described structure of the braid 11 applies to all embodiments of this application. The exemplary embodiments according to FIGS. 1-3 have closed end loops and the embodiments according to FIGS. 4-9 have open end loops.

Closed end loops 16a, 16b, 16c, 16d are each formed from at least one continuous wire element 12, which has two sections 20a, 20b, the axial components of which run in the opposite direction of the wire. The

Axial components are aligned in the longitudinal direction of the hollow body. The

Axial component of the first (left in Figure 1) portion 20a extends in the circumferential direction ULR seen in the wire in the proximal direction or in the feed direction EZ. Seen in the same direction of rotation ULR, the axial component of the second section 20b extends counter to the feed direction EZ. This means that the two axial components of the first and second sections 20a, 20b extend in the longitudinal direction L of the hollow body, wherein in the same

Direction of rotation ULR opposite direction of the axial components is opposite. The first end loop 16a and / or the other end loops 16b, 16c, 16d can each be formed from a single wire element 12. It is also possible to form the first end loop 16a and / or the other end loops 16b, 16c, 16d respectively by a plurality of wire elements 12, each extending continuously along the end loop 16a, 16b, 16c, 16d, even in the region of the top 31st Throughout in this context means that the wire elements 12 are in one piece in the region of the end loops.

As can be seen in FIG. 1, the end loops 16a, 16b, 16c, 16d are connected to one another in such a way that the end loops are movable and at the same time stabilized relative to one another in the longitudinal direction of the hollow body. This applies to everyone

Embodiments, wherein the type of connection between the end loops 16a, 16b, 16c realized differently. The connection between the end loops 16a, 16b, 16c, 16d is punctiform, in particular selectively centered on the end loops 16a, 16b, 16c. This means that the tips of the end loops 16a, 16b, 16c are connected to one another in the unwinding according to FIG. 1 or the parts of the end loops 16a, 16b, 16c, 16d which are the most proximally projecting in the spatial state of the hollow body 10. The compound can be regarded as a linear compound in contrast to mesh-like compounds.

In this case, a single connection is provided, on the one hand has the function to stabilize the end loops in the radial direction relative to the hollow body to improve the guidance when re-retracting, and on the other hand, the decoupling of the end loops 16a, 16b, 16c of the mesh 13 of the braid maintain. For this purpose, the connection between the end loops 16a, 16b, 16c allows a

Relative movement of the end loops 16a, 16b, 16c in the longitudinal direction of the hollow body to each other. The connection is thus designed so that the distance between the end loops 16a, 16b, 16c in a deformation when the hollow body 10 is withdrawn into the feed system can change, in particular can increase.

Instead of the single connection between the end loops 16a, 16b, 16c, two corresponding connections may be provided which extend in the axial direction parallel to the central axis of the hollow body and which allow a relative movement of the end loop 16a, 16b, 16c to each other. It is also possible to provide more than two such connections, which as a whole maintain the decoupling of the end loops 16a, 16b, 16c from the mesh-shaped region of the braid 11.

As can be seen in FIG. 1, the connection of the end loops 16a, 16b, 16c to the innermost end loop 16d achieves a further stabilizing effect. The connection with the innermost end loop 16d is not mandatory since By the connection of the other end loops 16a, 16b, 16c with each other already a good stability is created.

All the above statements regarding the connection between the end loops 16a, 16b, 16c, 16d apply to all embodiments.

Specifically, in the embodiment of Figure 1, the decoupling of

End loops 16a, 16b, 16c, 16d realized by the mesh-shaped part 26 of the braid 11 by an elongated connecting element 17, whose main orientation extends in the longitudinal direction of the hollow body. The connecting element 17 is in

Longitudinal direction of the hollow body 10 flexible, as shown schematically by the spring-like design of the connecting element 17. This means that between the end loops 16a, 16b, 16c, 16d respectively spring elements or elastic elements 27 are provided, which can be deflected in the longitudinal direction of the hollow body 10 to allow a change in distance between the end loops 16a, 16b, 16c, 16d. Instead of the spring elements 27, the areas provided between the end loops 16a, 16b, 16c, 16d can be bridged by an elastic connecting element 17, which has the same function as the spring elements 27. In this case, the flexibility of the connecting member 17 in the longitudinal direction is caused by elastic deformation of the connecting member 17.

Since the flexibility of the connecting element 17 in the longitudinal direction is generally greater than the flexibility in the radial direction relative to the hollow body 10, on the one hand the change in distance between the end loops 16a, 16b, 16c, 16d is made possible and on the other hand a radial deflection of the end loops 16a, 16b, 16c 16d prevents or impedes. It is thereby achieved that the end loops 16a, 16b, 16c, 16d remain in the wall plane of the braid 11 during retraction into the feed system, so that jamming is prevented or the risk of jamming is reduced without the braid being distorted.

The connecting element 17 has a connecting portion 28 which extends from the first end loop 16a in the proximal direction. The connecting portion 28 may be fixedly or detachably connected to a guide wire or generally an actuating element, by which a tensile force in the proximal direction can be exerted on the hollow body 10. The guidewire (not shown) may extend from the connecting portion 28 in a manner known per se be decoupled, for example, when the device designed as a stent completely discharged from the feed system and positioned correctly. In the case of the formation of the device as thrombus catcher or generally as

Thrombectomy device, the guide wire with the connecting portion 18 fixed, for example, be integrally connected.

The remarks on the connecting portion 28 will be disclosed in connection with all embodiments.

In the exemplary embodiments according to FIGS. 2 and 3, further possibilities are described how the flexibility of the connecting element 13 can be realized. In this case, an additional connecting element 17 is used, specifically in the form of a connecting wire 18, which is coupled to the end loops 16a, 16b, 16c, 16d. The use of a connecting wire 18 for coupling the end loops 16a, 16b, 16c, 16d has the advantage that no elements, such as in spring or coil type systems, extend radially outwardly or inwardly outside the mesh plane, which disturb the blood flow and the Pulling the braid into the catheter could complicate it. In general, the elastic and / or resilient connecting elements 17 are adapted to their size and shape to the mesh level or the wall of the braid 11.

In the embodiment of Figure 2, a curved connecting wire 18 is provided, which is connected to the end loops 16a, 16b, 16c, 16d. Of the

Connecting wire 18 is in each case between the first and second end loop 16a, 16b and between the third and fourth end loop 16c, 16d curved such that the connecting wire 18 extends with respect to the longitudinal axis of the hollow body in sections in different directions. Specifically, that is

Connecting wire 18 alternately curved in different directions. The connecting wire 18 is formed several S-shaped, wherein the number of curvatures of the S-shape according to the number of end loops 16a, 16b, 16c, 16d or the number of spaces between the end loops 16a, 16b, 16c, 16d corresponds , In the embodiment according to FIG. 2, the connecting wire 18 is curved in a triple S-shape and thus has three curvatures assigned to the individual end loops 16a, 16b, 16c, 16d. The curvatures of the connecting wire 18 are arranged so that the connecting wire 18 sections in the same direction of the wire elements 12 of the staggered end loops 16a, 16b, 16c, 16d runs. As a result, the stability of the intake region 26 is increased. The connecting wire 18 thus runs in sections parallel to the first or

second portions 20a, 20b of the respective end loops 16a, 16b, 16c having oppositely disposed axial components. This results in the alternately opposing curvature of the connecting wire 18th Der

Connecting wire 18 or generally the connecting element 17 is arranged meandering.

The connecting wire 18 has a connecting portion 28 which, as in the exemplary embodiment according to FIG. 1, extends beyond the first end loop 16a in the proximal direction and serves to introduce force.

The connection of the connecting wire 18 with the end loops 16a, 16b, 16c and / or the first stitch 13a is made through openings 19 in the form of

Holes or holes which are arranged in the connecting wire 18 and in which the wire elements 12 of the end loops 16a, 16b, 16c, 16d are arranged. The wire elements 12 are threaded into the openings prior to the actual manufacture of the braid, whereby a relatively simple connection between the connecting wire 18 and the various elements of the braid is made. The openings 19 may also be formed in the form of laterally open recesses into which the wire is inserted. This can be done after braiding.

When compressing the hollow body and the associated

Distance increase between the end loops 16a, 16b, 16c, 16d, the multi-curved connecting wire 18 is stretched and assumes a rectilinear shape in extreme cases. The respective curvatures of the connecting wire 18 are designed so that a maximum change in distance between the

End loops 16a, 16b, 16c, 16d is possible.

In the embodiment according to FIG. 3, an alternative arrangement of the connecting wire 18 or an alternative connection of the connecting wire 18 to the end loops 16a, 16b, 16c, 16d is shown. The connection is non-positively, for example by sleeves 30 which are crimped and through which the connecting wire 18 and the wire elements 12 are guided. By the

Crimped the guide wire 28 and the wire elements 12 are firmly connected. It is also possible, the connecting wire 18 cohesively or positively to connect with the wire element 12 of the end loops. The positive connection can be done for example by twisting. The cohesive connection can be done by welding or gluing. The course of the connecting wire 18 corresponds to the course of the connecting wire 18 according to Figure 2. The relevant embodiments in connection with Figure 2 are also disclosed in connection with the embodiment of Figure 3.

As crimping elements, for example, radiopaque markers can be used. With regard to the other features of the embodiment of Figure 3, reference is made to the above statements.

In contrast to the embodiment according to FIG. 3, in which the end loops are closed, the end loops of the embodiment according to FIG. 4 are open. This means that each end loop 16a, 16b, 16c consists of at least two separate wire elements 12a, 12b which are not continuous, ie in the region of the end loops 16a, 16b, 16c, 16d, in particular in the region of the tips 31 of the end loops 16a, 16b , 16c, 16d have free wire ends.

Generally and with regard to the exemplary embodiments according to FIGS. 4-9, it is disclosed that the separate wire elements 12a, 12b of an open end loop 16a, 16b, 16c are formed such that in each case a wire element 12a of the open end loops has two sections 21a, 21b, in the course of the wire

form opposite circumferential components. The opposite

Peripheral components extend in the circumferential direction of the hollow body. These

Wire members 12a are curved such that the first portion 21 and the second portion 21b have opposite circumferential components when viewed in the wire path. The wire element 12a thus changes the circumferential or the

Winding direction in the course of the end loop. In the example according to FIG. 4, these are in each case the left wire elements 12a of the end loops 16a, 16b, 16c, 16d. The respective other separate wire elements 12b of an end loop 16a, 16b, 16c, 16d extend in a straight line in the same circumferential direction or have no change in the circumferential direction. The curved wire elements 12 are deformed in such a way that they extend in sections, in particular in the region of the second section 21b, parallel to the respective other separate wire elements 12b of an end loop 16a, 16b, 16c. Thus, the peripheral component of the second portion 21b corresponds of the one wire element 12a of the peripheral component of the respectively associated other wire element 12b of an end loop 16a, 16b, 16c.

As can be seen in FIG. 4, the connecting wire 18 is connected to a first section 21a of an end loop 16a, 16b, 16c and a second section 21b of the next end loop 16a, 16b, 16c, the first section 21a of the one end loop 16a, 16b, 16c and the second portion 21b of the next end loop 16a, 16b, 16c have opposite peripheral components. In Fig. 4, the reference numeral 21b for the second portion on the crimping sleeve 30, as the second portion 21b of the end loop 16a, 16b, 16c extends substantially within the crimping sleeve 30.

Based on the respectively curved wire elements 12a of an end loop 16a, 16b, 16c, the connecting wire 18 is connected to the second section 21b of FIG

curved wire elements 12a connected. This results in the multiply curved shape of the connecting wire 18, the sections along the extending in the same direction separate wire elements 12a, 12b a

End loop 16a, 16b, 16c extends. The connecting wire 18 is through

Crimp connections, in particular by sleeves 30 with the wire elements 12a, 12b connected. In this case, both the connecting wire 18 and the wire elements 12a, 12b of an end loop 16a, 16b, 16c, 16d in the respective sleeves 30th

arranged, as shown in Figure 4 can be seen. The separate wire elements 12a, 12b and the connecting wire 18 can be connected to one another in another way, for example by material bonding (for example by welding or gluing) or by form-locking (for example by twisting).

In the embodiment of Figure 4, the flexibility of

Connecting wire, as described above, by the sections

Curvature of the connecting wire 18 allows the length compensation in the deformation of the end loops 16 a, 16 b, 16 c when retracted by a

Stretching of the curved portions of the connecting wire 18 causes.

The exemplary embodiment according to FIG. 5 differs from the above-mentioned exemplary embodiments in that, as in the above-mentioned exemplary embodiments, an additional connecting element 17 is not used, but rather the connecting element 17 through the wire elements 12a, 12b End loops 16a, 16b, 16c is realized. Otherwise this corresponds to

Embodiment according to Figure 5 the above embodiments. The end loops 16a, 16b, 16c, 16d are open in the embodiment according to FIG. 5 and each comprise at least two separate wire elements 12a, 12b. For the arrangement and the course of the separate wire elements 12a, 12b, reference is made to the statements in connection with the embodiment according to FIG. The connecting element 17 is formed by the separate wire elements 12a, 12b of the end loops 16a, 16b, 16c, 16d. These are the separate

Wire elements 12a, 12b of the innermost (eg fourth) end loop 16d extended and merged with the separate wire elements 12a, 12b of the next end loop (third end loop 16c). The wire elements 12a, 12b coming from the first loop 13a are curved and adapted to the course of the one wire element 12a of the next end loop 16c. The other wire element of the next end loop 16a is curved such that the winding direction of the other wire element changes and thus matches the winding direction of the wire elements 12a, 12b coming from the innermost end loop 16d and the winding direction of the other wire element 12a of the next end loop 16a. The construction of the connection between the third end loop 16c and the next (second end loop 16b) takes place in a corresponding manner. This also applies to the connection between the second end loop 16b and the first end loop 16a. In all cases, the separate wire elements 12a, 12b of the preceding end loop 16b, 16c are extended and brought together with the separate wire elements 12a, 12b of the subsequent end loops 16b, 16a. This results in the meandering or multiple in the opposite direction curved connection between the end loops 16a, 16b, 16c and the first end loop 13a, whereby a longitudinally flexible coupling of the above elements is achieved with simultaneous fixation in the radial direction.

The fixing of the separate, merged wire elements 12a, 12b takes place in each case by a fixed connection, in particular by a cohesive, non-positive or positive connection. In the embodiment according to FIG. 5, a frictional connection in the form of crimp sleeves 30 is provided

intended. The fixed connection takes place in each case in the region of the second section of the curved wire element 12b of an end loop 16a, 16b, 16c and comprises all merged wire elements 12a, 12b, ie both the separate wire elements of the end loop 16a, 16b, 16c, 16d and the extended Wire elements 12a, 12b of the longitudinally upstream end loop 16b, 16c, 16d. As a result, a connection point 22 is formed.

The wire elements of the respectively upstream end loop 16a, 16b, 16c are cut off after the connection point 22 (corresponding to the crimping sleeve 30) or end there. Only the separate wire elements 12a, 12b of each upstream

End loop 16a, 16b, 16c, 16d are extended and with each

downstream end loop 16a, 16b, 16c connected, so that in total the number of wire elements of the connecting element 17 is constant. This can alternatively be achieved in that the supplied wire elements 12a, 12b end after the connection point 22 and the wires of the respective upstream end loop 16a, 16b, 16c, 16d are extended or continued. The connection point 22 or generally the connection of the individual separate wire elements 12a, 12b can alternatively be realized by welding, gluing or by twisting.

The merged wire elements 12a, 12b can be parallel and rectilinear. Alternatively, the merged wire elements may be partially twisted. It is also possible that only the respectively extended wire elements 12a, 12b, which extend along the entire connecting element 17, are twisted. The respectively supplied wire elements of the upstream end loop 16b, 16c, 16d can be guided parallel to the twisted wire elements 12b and not be twisted.

The embodiment according to FIG. 6 differs from the exemplary embodiment according to FIG. 5 in that the merged wires are the innermost ones

End loop 16d and the downstream end loops 16a, 16b, 16c are each twisted together. This means that the number of wire elements of the connecting element 17 increases in the longitudinal direction and in the proximal direction. The additional connection points 22 according to FIG. 5 are omitted. The course of the

Connecting element 17 and the successively merged wire elements 12a, 12b corresponds to the course of the illustrated in the preceding embodiments or described connecting element 17 and des

Connecting wire 18. In the above-mentioned embodiments, the length compensation between end loops 16a, 16b, 16c, 16d is effected by the flexibility of

Connecting element 17.

In contrast, in the embodiments according to FIGS 7-9, the length compensation between the end loops 16a, 16b, 16c, 16d by a

slidable connection of the end loops 16a, 16b, 16c, 16d and the

Connecting element 17, specifically the connecting wire 18. It is also possible, the flexible connecting element 17 with the sliding sliding connection to

combine. For example, the connecting element 17 may be elastically deformable and at least with a part of the end loops 16a, 16b, 16c, 16d

be slidably connected.

Concretely, the connecting element 17 is formed according to Figure 7 as a connecting wire 18 which is connected to the end loops 16a, 16b, 16c, 16d each by a lubricant 23. The lubricant 23 is realized in the embodiment of Figure 7 each as a sleeve. It is also possible to use coils instead of the sleeve. Further, it is possible to deform the wire elements themselves in the region of the tip 31 of the respective end loop 16a, 16b, 16c, 16d into a loop which serves as a lubricant 23.

The concept of the slidable connection is generally applicable to open or closed end loops.

In the embodiment according to FIG. 7, the concept is described in connection with open end loops. The various embodiments of the lubricant 23 (sleeve, coil, loop, etc.) can be combined. The

separate wire elements 12a, 12b or generally the wire elements 12a, 12b of the end loops 16a, 16b, 16c, 16d are firmly connected to the lubricant 23. In the embodiment according to FIG. 7, the free ends of the wire elements 12a, 12b are arranged and fastened in bores or in an annular gap in the wall of the sleeve, which extends in the axial direction. Other connections between the free ends and the lubricant 23, for example by welding, gluing or by non-positive or positive connections are possible. The lubricant 23 comprises an opening 32 extending in the longitudinal direction of the hollow body or in the feed direction EZ, in which the connecting wire 18 is arranged. The Openings 32 of the lubricant 23 are arranged in alignment. The connecting wire 18 is straight, so in contrast to the above-mentioned embodiments, not curved.

The power transmission from the guide wire or the actuating element on the hollow body 10 can be done in various ways. For example, the

Guidewire with the lubricant 23 of the first end loop 16a, so the proximal foremost end loop 16a to be firmly connected. The guidewire or the

Actuator can also with another sleeve or with another

Lubricant 23 may be connected, for example, with the lubricant 23, which is connected to the innermost end loop 16 d, so that the force is applied close to the mesh-shaped part 26 of the braid 11. It is also possible the

Connecting wire 18 to be firmly connected to one of the sliding means 23 or with one of the sleeves, so that it is slidable only with respect to the remaining lubricant 23 and the respective end loops. The connecting wire 18 is in this case fixed to the guide wire, for example in one piece with the

Guidewire connected.

In all cases, it applies that the guidewire is permanently or detachably connected to the connecting wire 18, depending on the application of the device. In the case of a stent, a decoupling mechanism is provided, either directly on one of the

Lubricant 23 or one of the sleeves or on the connecting wire 18 is formed, depending on where the force is applied. The length of the connecting wire 18 in the distal direction is dimensioned so that a maximum change in distance between the end loops 16a, 16b, 16c, 16d is possible without the connecting wire 18 is released from the lubricants 23.

The connecting wire 18 on the one hand causes a radial fixation of the end loops, so that tilting during retraction is avoided. The radial fixation is improved in that the connecting wire 18 is slidably or fixedly connected to the first end loop 13a and thus to the mesh-shaped portion 26. The change in length of the other elements of the catchment area is achieved by the slidable connection in the axial direction between the wire elements 12a, 12b and the end loops 16a, 16b, 16c and the connecting wire 18. It is also conceivable to omit the connection with the innermost end loop 16d and to couple only the end loops 16a, 16b, 16c with each other. As in the above-mentioned embodiments, the connection between the mesh-shaped part 26 of the braid 11 and the end loops 16a, 16b, 16c is such that a length compensation between the first stitch 13a and the next end loop 16c allows and the decoupling of the end loops 16a, 16b, 16c of the mesh-shaped part 26 of the braid 11 is maintained.

An alternative of the embodiment according to FIG. 7 is shown in FIG. The embodiment of Figure 8 corresponds to the embodiment of Figure 7, except that the connecting wire 18 is slidably disposed in each sliding means 23 and has a plurality of stops 24 which are fixedly connected to the connecting wire 18. The stops 24 cooperate with at least one lubricant 23 such that an axial movement of the

Connecting wire relative to the end loop, in particular in the feed direction EZ of the hollow body is subjected to a tensile force. In this case, a single stop 24 may be provided, which cooperates with a lubricant 23. In which

Embodiment according to Figure 8, a plurality of stops 24 are provided, which are arranged offset on the guide wire 18 so that they successively with the respective associated lubricants 23 come into contact when the

Connecting wire 18 is moved in the feed direction EZ. The distance between the individual stops 24 therefore increases in the distal direction. In an extended configuration of the end loops 16a, 16b, 16c, the respective stops 24 are in contact with the associated lubricants 23, so that the tensile force evenly distributed over all end loops 16a, 16b, 16c as well as the first stitch 13a in the

Hollow body 10 is introduced.

The embodiment according to FIG. 9 is also based on the concept of the sliding connection. In this case, the connecting element 17 on the one hand comprises a lubricant 23 and on the other hand, the merged in the axial direction

Wire elements 12a, 12b of the open end loops 16a, 16b, 16c, 16d. In which

Embodiment according to Figure 9, the lubricant 23 on the one hand firmly with the first end loop 16a, which forms the end edge 14, and on the other hand slidably connected to the merged, separate wire elements 12a, 12b of the next end loops 16b, 16c, 16d. Specifically, the free ends of the

merged wire elements 12a, 12b arranged longitudinally displaceable in the lubricant 23. In contrast to the exemplary embodiment according to FIG. 5 or FIG. 6, in which the merged wire elements are alternately curved, the separate wire elements 12a, 12b according to FIG. 9 extend in a straight line in the longitudinal axial direction of the hollow body. The merged wire elements 12a, 12b may be partially twisted and / or run untwisted parallel to each other. The free ends of the separate wire elements are arranged longitudinally displaceable in the lubricant 23, in particular in a sleeve. The lubricant 23 is firmly connected to the separate wire elements 12a, 12b of the first end loop 16a, via which the force is applied. The lubricant 23 is connected to a guidewire at the proximal end. The guidewire and the free ends of the separate wire elements 12a, 12b are coaxially arranged in the lubricant 23, with a free space between the free ends and the guidewire such that there is sufficient space for the movement of the free ends.

The extension of the wire elements of the one end loop is with respect to

Wire elements of the next end loop relatively movable to allow an extension of the cell or the end loop. The sleeve or the lubricant 23 may be profiled so that it is flexible in its length, comparable to at

so-called hypotubes. Instead of the sleeve, the lubricant 23 may be realized by a coil. The coil may for example be formed from the separate wire element 12a, 12b of the first end loop 16a.

Figures 13 to 17 show embodiments in which the end edge 14 is only partially free of the mesh 13 of the braid 11. The illustrated pins at the deflection of the wires do not belong to the device, but to the production mandrel. In the embodiments according to FIGS. 13, 14, only a proximal front region, in particular the proximal front half of the first end loop 16 a, is loop-free or loop-free in the region of the tip 31. This area is symmetrical. The other half or the other region of the first end loop 16a is connected to the mesh by overlapping loops, which are the

Couple end edge 14 in sections with the braid. The coupling of the first and adjacent second end loop 16a, 16b is carried out by the flexible connecting element 17 in the region of the tip 31, which in the form of

merged wires of the open loops (Fig. 13) or in the form of a spring element (Fig. 14) is realized. In the embodiment according to FIG. 15, the mesh or loop-free region is asymmetrical and is formed only on one side of the tip 31. The

Connecting element 17 corresponds to Fig. 13. This is a higher

Braid stability in the back and caused by the front large loop cells a good retractability.

The embodiment according to FIG. 16 differs from that

Embodiment according to FIG. 13 in that the loop-free region is formed away from the tip 31, in particular in the distal rear half of the end loop 16a. The other half or the proximal front region at the top is coupled by overlapping loops with the mesh-shaped part of the braid. The fourth or innermost end loop 16d is through the

Connecting element 17 is connected to the first loop 16a and that comparable to the connecting element according to FIG. 16. This has the advantage that in the middle a greater braiding stability is achieved. The laterally larger loop cells improve the retractability.

The device according to the invention can be designed as an implant or as a medical device that is temporarily released in a vessel, such as baskets, in particular thrombosis scavengers. As implants are for example stents in question. For implants, the advantage of the invention is that after checking the position of the implant, the user, if a wrong

Positioning is noted, the implant re-enter the catheter and this new, for example, to position an aneurysm or stenosis. For temporarily released devices, such as baskets or filters, the function of recoverability is to remove particles trapped in the basket or filter, such as clots, from the vessel or other hollow organs.

LIST OF REFERENCE NUMBERS

10 hollow bodies

 11 braid

 12 wire element

 13 mesh

14 end edge axial end

 End loop first end loop, 16c, 16d second end loop

 connecting element

connecting wire

opening

a, 21a first section b, 21b second section

 Joint Lubricant

 attack

Claims

claims 1. Medical device for import into a hollow body organ with a  Hollow body (10) of a braid (11) made of wire elements (12), which cross each other to form meshes (13), the braid (11) a  End edge (14) defining an axial end (15) of the hollow body (10),  d a d u r c h e c e n c i n e s that  the end edge (14) in the circumferential direction of the hollow body (10)  is continuously circumferentially arranged and formed by a first end loop (16a), wherein the first end loop (16a)  arranged obliquely with respect to the longitudinal axis of the hollow body (10) is such that the first end loop (16a) forms a tip, at least one wire element (12) of the braid (11), along the circumference of the end edge (14) continuously at least extends to the tip of the first end loop (16a), and at least in sections, in particular on the entire circumference of the terminal edge (14), free from the mesh (13) of the braid (11), and at least one second end loop (16b, 16c, 16d) offset inwardly in the direction of the longitudinal axis of the hollow body (10) and spaced from the first end loop (16a), wherein the second end loop (16b, 16c, 16d)  extends at least in sections along the first end loop (16a) and forms a point and  - At least one wire element (12) of the braid (11), which extends continuously at least to the tip of the second end loop (16 b, 16c, 16d), wherein the first and second end loops (16a, 16b, 16c, 16d) are elastically and / or flexibly connected to each other such that the end loops (16a, 16b, 16c, 16d) are movable relative to one another in the longitudinal direction of the hollow body (10). 2. Apparatus according to claim 1  d a d u rc h e ke n ze i c h n et that  the interconnected end loops (16a, 16b, 16c, 16d) are connected by an elongated connecting element (17) whose main orientation extends in the longitudinal direction of the hollow body (10). 3. Apparatus according to claim 2  There is no mention that  the connecting element (17) is flexible in the longitudinal direction of the hollow body (10). 4. Device according to one of the preceding claims  d a d u rc h e e n c e s n e s that  the connecting element (17) comprises at least one connecting wire (18), which is in each case curved between the end loops (16a, 16b, 16c, 16d) such that the connecting wire (18) with respect to the longitudinal axis of the hollow body (10) sections in different  Directions extends. 5. Apparatus according to claim 4  d a d u rc h e e n c e s n e s that  the connecting wire (18) is single or multiple S-shaped. 6. Apparatus according to claim 4 or 5  There is no mention that  the connecting wire (18) sections in the same direction of the  Wire elements (12) of the staggered end loops (16a, 16b, 16c, 16d) extends. 7. Device according to one of claims 4 to 6  d a d u rc h e e n c e s n e s that  the connecting wire (18) has openings (19) in which the Wire elements (12) of the end loops (16a, 16b, 16c, 16d) are arranged. 8. Device according to one of claims 4 to 7  d a d u rc h e e n c e s n e s that  the connecting wire (18) is connected to the wire elements (12) of the end loops (16a, 16b, 16c, 16d) in a material-locking, force-locking or form-fitting manner. 9. Device according to one of claims 4 to 8  d a d u rc h e e n n e s n e s that  the end loops (16a, 16b, 16c, 16d) form closed loops, each with at least one continuous wire element (12), the two  Sections (20a, 20b) with opposite in the wire path  Axial components extending in the longitudinal direction of the hollow body (10), wherein the connecting wire (18) with a first portion (20a) of an end loop (16a, 16b, 16c, 16d) and a second portion of the next end loop (16a, 16b, 16c , 16d), wherein the first portion (20a) of the one end loop (16a, 16b, 16c, 16d) and the second portion (20b) of the next end loop (16a, 16b, 16c, 16d) have opposing axial components. 10. Apparatus according to claim 8  d a d u rc h e e n c e s n e s that  the end loops (16a, 16b, 16c, 16d) form open loops, each with at least two separate wire elements (12a, 12b), one of which  Wire element (12a) has two sections (21a, 21b) with opposite in the wire course peripheral components, in the circumferential direction of  Hollow body (10) extend, wherein the connecting wire (18) with a first portion (21a) of an end loop (16a, 16b, 16c, 16d) and a second portion (21b) of the next end loop (16a, 16b, 16c, 16d) connected wherein the first portion (21a) of the one end loop (16a, 16b, 16c, 16d) and the second portion (21b) of the next end loop (16a, 16b, 16c, 16d) have opposite peripheral components. 11. Apparatus according to claim 1 or 2  d a d u rc h e e n c e s n e s that the end loops (16a, 16b, 16c, 16d) form open loops, each with at least two separate wire elements (12a, 12b), one of which Wire element (12 a) has two sections (21 a, 12 b) with opposite in the wire course peripheral components, which in the circumferential direction of the  Hollow body (10) extend, and the connecting element (17) through the separate wire elements (12a, 12b) of the end loops (16a, 16b, 16c, 16d) is formed, wherein at least one wire element (12a, 12b) of the one  End loop (16a, 16b, 16c, 16d) and at least one wire elements (12a, 12b) of the next end loop (16a, 16b, 16c, 16d) are merged and the winding direction of the merged wire elements (12a, 12b) changes such that the Wire elements (12a, 12b) on the one hand in the direction of a first portion (21a) of an end loop (16a, 16b, 16c, 16d) and on the other hand in the direction of a second portion (21b) of the next  End loop (16a, 16b, 16c, 16d) are arranged, wherein the first portion (21a) of the one end loop (16a, 16b, 16c, 16d) and the second portion (21b) of the next end loop (16a, 16b, 16c, 16d ) have opposite circumferential components. 12. Device according to claim 11  d a d u rc h e ke n ze ze ch n et that  the wire elements (12a, 12b) of the one end loop (16a, 16b, 16c, 16d) are connected to the wire elements (12a, 12b) of the next end loop (16a, 16b, 16c, 16d) and form a connection point (22) the  Wire elements (12a, 12b) of the next end loop (16a, 16b, 16c, 16d) after the connection point (22) terminate such that the number of wire elements (12a, 12b) remains constant in the longitudinal direction of the hollow body (10). 13. Device according to claim 11  d a d e d e r c e n ts i c h n et that  the wire elements (12a, 12b) of the one end loop (16a, 16b, 16c, 16d) are fed to the wire elements (12a, 12b) of the next end loop (16a, 16b, 16c, 16d) such that the number of merged wire elements (12a , 12b) in the longitudinal direction of the hollow body (10) increases. 14. Device according to claim 2  d a d u rc h e e n c e s n e s that the connecting element (17) and at least one end loop (16a, 16b, 16c, 16d) are slidably connected in the longitudinal direction of the hollow body (10). 15. Device according to claim 14  d a d u rch e ke n ze i c h n et that  the connecting element (17) comprises at least one connecting wire (18) which is slidably connected to the end loops (16a, 16b, 16c, 16d) in each case by a sliding means (23), in particular by sleeves and / or coils. 16. Device according to claim 15  there is no evidence that  the connecting wire (18) has at least one stop (24) which cooperates with a sliding means (23) by an axial movement of the connecting wire (18) relative to the end loop (16a, 16b, 16c, 16d) and the hollow body (10) with a Tensile force applied. 17. Device according to claim 14  d a d u rc h e ke n ze ze ch n et that  the connecting element (17) comprises a sliding means (23) fixed on the one hand firmly to the first end loop (16a), which forms the end edge (14), and on the other hand slidably displaceable with the separate wire elements (12a, 12b) of the at least one second open end loop (16). 16b, 16c, 16d), wherein the separate wire elements (12a, 12b) are brought together in the longitudinal direction of the hollow body (10) and whose free ends are arranged in the lubricant (23).