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WO2011118960A3 - 나노입자 제조방법 - Google Patents

나노입자 제조방법 Download PDF

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Publication number
WO2011118960A3
WO2011118960A3 PCT/KR2011/001956 KR2011001956W WO2011118960A3 WO 2011118960 A3 WO2011118960 A3 WO 2011118960A3 KR 2011001956 W KR2011001956 W KR 2011001956W WO 2011118960 A3 WO2011118960 A3 WO 2011118960A3
Authority
WO
WIPO (PCT)
Prior art keywords
particles
preparing nano
nano
preparing
active materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2011/001956
Other languages
English (en)
French (fr)
Other versions
WO2011118960A2 (ko
Inventor
김갑식
박주원
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Synectics Inc
Original Assignee
Bio Synectics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Synectics Inc filed Critical Bio Synectics Inc
Priority to EP11759709.6A priority Critical patent/EP2551237B1/en
Priority to US13/635,717 priority patent/US8828445B2/en
Priority to CN201180015605.2A priority patent/CN102858682B/zh
Priority to JP2013501184A priority patent/JP5793179B2/ja
Priority to AU2011230144A priority patent/AU2011230144B2/en
Priority to CA2793241A priority patent/CA2793241C/en
Publication of WO2011118960A2 publication Critical patent/WO2011118960A2/ko
Publication of WO2011118960A3 publication Critical patent/WO2011118960A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C13/00—Disintegrating by mills having rotary beater elements ; Hammer mills
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C4/00—Crushing or disintegrating by roller mills

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

본 발명은 나노수준의 활성물질 입자 제조방법에 관한 것으로서, 보다 상세하게는, 분쇄공정을 통해 활성물질 함유 나노입자를 간단하게 우수한 효율로 제조할 수 있는 방법에 관한 것이다.
PCT/KR2011/001956 2010-03-22 2011-03-22 나노입자 제조방법 Ceased WO2011118960A2 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP11759709.6A EP2551237B1 (en) 2010-03-22 2011-03-22 Method for preparing nano-particles
US13/635,717 US8828445B2 (en) 2010-03-22 2011-03-22 Method for preparing nano-particles utilizing a saccharide anti-coagulant
CN201180015605.2A CN102858682B (zh) 2010-03-22 2011-03-22 纳米颗粒制备方法
JP2013501184A JP5793179B2 (ja) 2010-03-22 2011-03-22 ナノ粒子の製造方法
AU2011230144A AU2011230144B2 (en) 2010-03-22 2011-03-22 Method for preparing nano-particles
CA2793241A CA2793241C (en) 2010-03-22 2011-03-22 Method for preparing nano-particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20100025486 2010-03-22
KR10-2010-0025486 2010-03-22

Publications (2)

Publication Number Publication Date
WO2011118960A2 WO2011118960A2 (ko) 2011-09-29
WO2011118960A3 true WO2011118960A3 (ko) 2012-01-26

Family

ID=44673746

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/001956 Ceased WO2011118960A2 (ko) 2010-03-22 2011-03-22 나노입자 제조방법

Country Status (8)

Country Link
US (1) US8828445B2 (ko)
EP (1) EP2551237B1 (ko)
JP (1) JP5793179B2 (ko)
KR (1) KR101834940B1 (ko)
CN (1) CN102858682B (ko)
AU (1) AU2011230144B2 (ko)
CA (1) CA2793241C (ko)
WO (1) WO2011118960A2 (ko)

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US9763514B2 (en) 2011-01-21 2017-09-19 Michael Blair Knock-down furniture
US8684466B2 (en) 2011-01-21 2014-04-01 Michael Blair Modular knock-down upholstered furniture
KR101794032B1 (ko) * 2011-09-21 2017-11-07 (주)바이오시네틱스 나노입자 제조방법
KR101772263B1 (ko) * 2012-05-11 2017-08-28 액티버스 파마 컴퍼니 리미티드 유기 화합물 나노분체, 그 제조 방법 및 현탁액
KR102239352B1 (ko) 2013-09-27 2021-04-13 대우조선해양 주식회사 원유저장탱크 레벨 및 밀도측정장치, 이의 밀폐시스템
KR20160133434A (ko) * 2014-03-10 2016-11-22 고쿠리츠다이가쿠호우진 도쿄다이가쿠 수분산성 비정질 입자 및 그 조제 방법
EP3212212B1 (en) 2014-10-31 2020-09-23 Monash University Powder formulation
KR101865712B1 (ko) * 2016-11-17 2018-06-08 주식회사 프롬바이오 나노입자화를 통해 분산력 및 수용화력이 높아진 매스틱 검 수용액 제조방법
CN109152745A (zh) * 2017-04-21 2019-01-04 株式会社生物研究 利用脂质作为研磨工序中的润滑剂的制备活性物质纳米粒子的方法
CN108409821A (zh) * 2018-03-19 2018-08-17 青岛国海生物制药有限公司 一种醋酸甲地孕酮纳米结晶的制备方法及醋酸甲地孕酮
JP2020152673A (ja) * 2019-03-20 2020-09-24 株式会社リコー ナノ粒子及びナノ粒子の製造方法、並びに医薬
CN109965167B (zh) * 2019-04-15 2022-02-15 江南大学 一种二十八烷醇运动饮料及其制备方法
CN114470508B (zh) * 2022-01-26 2023-07-21 中原工学院 一种具有药物缓释作用的理疗盐枕材料、制备方法和应用

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* Cited by examiner, † Cited by third party
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US20060073203A1 (en) * 2003-03-14 2006-04-06 Camurus Ab Dry polymer and lipid composition
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JP2010500340A (ja) * 2006-08-11 2010-01-07 パナセア バイオテック リミテッド 活性成分を送達するための粒子、その製造方法、および組成物

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US20060073203A1 (en) * 2003-03-14 2006-04-06 Camurus Ab Dry polymer and lipid composition
KR20070107841A (ko) * 2006-05-04 2007-11-08 김갑식 디올 화합물을 이용한 나노수준의 활성물질 입자 제조 방법
JP2010500340A (ja) * 2006-08-11 2010-01-07 パナセア バイオテック リミテッド 活性成分を送達するための粒子、その製造方法、および組成物
KR20080017161A (ko) * 2006-08-21 2008-02-26 광주과학기술원 다당류-기능화 나노입자 및 수화젤 담체를 포함하는복합체, 이를 포함하는 서방형 약물전달 제제, 뼈충진제 및이들의 제조방법

Also Published As

Publication number Publication date
EP2551237B1 (en) 2024-09-04
CA2793241A1 (en) 2011-09-29
US20130005643A1 (en) 2013-01-03
KR20110106247A (ko) 2011-09-28
AU2011230144B2 (en) 2015-01-22
CN102858682A (zh) 2013-01-02
EP2551237A2 (en) 2013-01-30
CA2793241C (en) 2020-07-14
JP5793179B2 (ja) 2015-10-14
US8828445B2 (en) 2014-09-09
AU2011230144A1 (en) 2012-10-18
WO2011118960A2 (ko) 2011-09-29
EP2551237A4 (en) 2014-01-22
KR101834940B1 (ko) 2018-03-06
JP2013522358A (ja) 2013-06-13
CN102858682B (zh) 2014-07-16

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