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WO2011100065A3 - Systems, devices, and methods including a dark-field reflected-illumination apparatus - Google Patents

Systems, devices, and methods including a dark-field reflected-illumination apparatus Download PDF

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Publication number
WO2011100065A3
WO2011100065A3 PCT/US2011/000259 US2011000259W WO2011100065A3 WO 2011100065 A3 WO2011100065 A3 WO 2011100065A3 US 2011000259 W US2011000259 W US 2011000259W WO 2011100065 A3 WO2011100065 A3 WO 2011100065A3
Authority
WO
WIPO (PCT)
Prior art keywords
systems
devices
dark
methods including
illumination apparatus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/000259
Other languages
French (fr)
Other versions
WO2011100065A2 (en
Inventor
Matthew R. Behrend
Michael C. Hegg
Matthew P. Horning
Benjamin K. Wilson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokitae LLC
Original Assignee
Tokitae LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/658,607 external-priority patent/US20100222774A1/en
Priority claimed from US12/925,650 external-priority patent/US8781184B2/en
Priority claimed from US12/925,653 external-priority patent/US9044141B2/en
Application filed by Tokitae LLC filed Critical Tokitae LLC
Priority to CN201180009054.9A priority Critical patent/CN102753887B/en
Priority to EP11742582.7A priority patent/EP2534415A4/en
Publication of WO2011100065A2 publication Critical patent/WO2011100065A2/en
Publication of WO2011100065A3 publication Critical patent/WO2011100065A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • A61B3/1225—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes using coherent radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/082—Condensers for incident illumination only
    • G02B21/084—Condensers for incident illumination only having annular illumination around the objective
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/10—Condensers affording dark-field illumination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N21/474—Details of optical heads therefor, e.g. using optical fibres
    • G01N2021/4742—Details of optical heads therefor, e.g. using optical fibres comprising optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N21/474—Details of optical heads therefor, e.g. using optical fibres
    • G01N2021/4752—Geometry
    • G01N2021/4759—Annular illumination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • G01N2333/445—Plasmodium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Emergency Alarm Devices (AREA)

Abstract

Systems, devices, and methods are described for providing a monitor or treatment device configured to, for example, detect hemozoin, as well as to monitor or treat a malarial infection.
PCT/US2011/000259 2010-02-10 2011-02-10 Systems, devices, and methods including a dark-field reflected-illumination apparatus Ceased WO2011100065A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201180009054.9A CN102753887B (en) 2010-02-10 2011-02-10 Comprise the system of details in a play not acted out on stage, but told through dialogues indirect illumination equipment, device and method
EP11742582.7A EP2534415A4 (en) 2010-02-10 2011-02-10 Systems, devices, and methods including a dark-field reflected-illumination apparatus

Applications Claiming Priority (18)

Application Number Priority Date Filing Date Title
US12/658,607 US20100222774A1 (en) 2007-12-11 2010-02-10 Systems, devices, and methods for inducing ultraviolet energy generation via hemozoin nanoparticles in a biological tissue
US12/658,617 2010-02-10
US12/658,619 US8467842B2 (en) 2010-02-10 2010-02-10 Systems, devices, and methods including multi-harmonic optical detection of hemozoin nanoparticles
US12/658,638 2010-02-10
US12/658,589 US8388509B2 (en) 2007-12-11 2010-02-10 Systems, devices, and methods including paramagnetic oscillation, rotation, and translation of hemozoin asymmetric nanoparticles in response to dark-field or Rheinberg detection of the presence of hemozoin
US12/658,580 2010-02-10
US12/658,607 2010-02-10
US12/658,638 US8585567B2 (en) 2007-12-11 2010-02-10 Systems, devices, and methods including paramagnetic oscillation, rotation and translation of hemozoin asymmetric nanoparticles in response to multi-harmonic optical detection of the presence of hemozoin
US12/658,619 2010-02-10
US12/658,617 US8840536B2 (en) 2007-12-11 2010-02-10 Systems, devices, and methods including paramagnetic oscillation, rotation and translation of hemozoin asymmetric nanoparticles in response to multi-harmonic optical detection of the presence of hemozoin
US12/658,589 2010-02-10
US12/658,580 US8504129B2 (en) 2007-12-11 2010-02-10 Systems, devices, and methods including enhanced dark field detection of hemozoin nanoparticles
US12/925,650 2010-10-25
US12/925,650 US8781184B2 (en) 2010-02-10 2010-10-25 Systems, devices, and methods for detection of malaria
US12/925,653 2010-10-25
US12/925,653 US9044141B2 (en) 2010-02-10 2010-10-25 Systems, devices, and methods including a dark-field reflected-illumination apparatus
US201113930611A 2011-01-10 2011-01-10
US12/930,611 2011-01-10

Publications (2)

Publication Number Publication Date
WO2011100065A2 WO2011100065A2 (en) 2011-08-18
WO2011100065A3 true WO2011100065A3 (en) 2011-11-03

Family

ID=56291212

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/000259 Ceased WO2011100065A2 (en) 2010-02-10 2011-02-10 Systems, devices, and methods including a dark-field reflected-illumination apparatus

Country Status (1)

Country Link
WO (1) WO2011100065A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12164097B2 (en) * 2020-02-24 2024-12-10 Massachusetts Institute Of Technology Bragg light source for dark-field imaging devices

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020155630A1 (en) * 2000-08-31 2002-10-24 Miho Iwabuchi Methods of inspecting and manufacturing silicon wafer, method of manufacturing semiconductor device, and silicon wafer
US6621568B1 (en) * 1999-06-30 2003-09-16 Nidek Co., Ltd. Defect inspecting apparatus
US20050087601A1 (en) * 2003-10-24 2005-04-28 Gerst Carl W.Iii Light pipe illumination system and method
US20070115461A1 (en) * 1995-06-06 2007-05-24 Kla-Tencor Corporation High throughput darkfield/brightfield wafer inspection system using advanced optical techniques
US20070236785A1 (en) * 2006-03-29 2007-10-11 Olympus Corporation Microscope
US20080297783A1 (en) * 2007-04-25 2008-12-04 Yuta Urano Defect inspection system and method of the same
US7461961B2 (en) * 2003-07-11 2008-12-09 Rudolph Technologies, Inc. Fiber optic darkfield ring light

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070115461A1 (en) * 1995-06-06 2007-05-24 Kla-Tencor Corporation High throughput darkfield/brightfield wafer inspection system using advanced optical techniques
US6621568B1 (en) * 1999-06-30 2003-09-16 Nidek Co., Ltd. Defect inspecting apparatus
US20020155630A1 (en) * 2000-08-31 2002-10-24 Miho Iwabuchi Methods of inspecting and manufacturing silicon wafer, method of manufacturing semiconductor device, and silicon wafer
US7461961B2 (en) * 2003-07-11 2008-12-09 Rudolph Technologies, Inc. Fiber optic darkfield ring light
US20050087601A1 (en) * 2003-10-24 2005-04-28 Gerst Carl W.Iii Light pipe illumination system and method
US20070236785A1 (en) * 2006-03-29 2007-10-11 Olympus Corporation Microscope
US20080297783A1 (en) * 2007-04-25 2008-12-04 Yuta Urano Defect inspection system and method of the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2534415A4 *

Also Published As

Publication number Publication date
WO2011100065A2 (en) 2011-08-18

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