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WO2011070485A1 - Module de mesure de gaz destiné à être utilisé dans des configurations thérapeutiques comprenant un micro-spectromètre à balayage réfléchissant - Google Patents

Module de mesure de gaz destiné à être utilisé dans des configurations thérapeutiques comprenant un micro-spectromètre à balayage réfléchissant Download PDF

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Publication number
WO2011070485A1
WO2011070485A1 PCT/IB2010/055535 IB2010055535W WO2011070485A1 WO 2011070485 A1 WO2011070485 A1 WO 2011070485A1 IB 2010055535 W IB2010055535 W IB 2010055535W WO 2011070485 A1 WO2011070485 A1 WO 2011070485A1
Authority
WO
WIPO (PCT)
Prior art keywords
electromagnetic radiation
infrared electromagnetic
optical element
collimated
measurement module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2010/055535
Other languages
English (en)
Inventor
James Torrance Russell
Michael Brian Jaffe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics NV filed Critical Koninklijke Philips Electronics NV
Priority to US13/514,476 priority Critical patent/US9510774B2/en
Priority to EP10798394.2A priority patent/EP2509494B1/fr
Priority to JP2012542659A priority patent/JP5938350B2/ja
Priority to CN201080055837.6A priority patent/CN102651996B/zh
Publication of WO2011070485A1 publication Critical patent/WO2011070485A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3504—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00—Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/10—Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00—Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/10—Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors
    • G01J5/20—Radiation pyrometry, e.g. infrared or optical thermometry using electric radiation detectors using resistors, thermistors or semiconductors sensitive to radiation, e.g. photoconductive devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3581—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using far infrared light; using Terahertz radiation

Definitions

  • the invention relates to an gas measurement module that is insertable into a
  • ventilation circuit and carries a microspectrometer configured to detect gas composition within the ventilation circuit.
  • Gas analyzers are widely used in medical applications and may be characterized as being located either in the main path of the patient's respiratory gases (mainstream analyzers) or in an ancillary path usually paralleling the main path (sidestream analyzers).
  • a mainstream analyzer is situated such that the subject's inspired and expired respiratory gases pass through an airway adapter onto which the analyzer is placed.
  • a sidestream gas analyzer is coupled to an airway adapter to draw air off from the main respiratory circuit for measurement.
  • Mainstream and sidestream designs for inclusion in gas measurement modules that can be coupled to a respiratory circuit in a therapeutic setting to measure gas composition must be designed to facilitate installation of the gas measurement modules at a patient's airway or in a respiratory circuit in communication with a patient in a location in relatively close proximity to the patient.
  • the gas analyzer must be designed such that the gas measurement module housing the gas analyzer has a convenient and comfortable form factor and/or weight. Further, the gas analyzer must be robust enough to be substantially unaffected by typical mechanical abuse and temperature variations associated with use in therapeutic settings.
  • the optics typically employed in these systems to process electromagnetic radiation generally form an optical path having a shape that adversely impacts the overall form factor of the spectrometer, and the gas measurement module as a whole. This impact may be due to one or both of the bulk of the optics and/or the optical path length and orientations dictated to process the electromagnetic radiation appropriately.
  • One aspect of the invention relates to a gas measurement module configured to be inserted into a ventilation circuit that is in fluid communication with an airway of a subject.
  • the gas measurement module comprises a chamber, an infrared source, a collimating reflective optical element, a diffractive reflective optical element, and a
  • the chamber has a first opening and a second opening, and is configured to form a flow path between the first opening and the second opening such that if the gas measurement module is inserted into the ventilation circuit, gas from the airway of the subject is transported through the flow path.
  • the infrared source is configured to emit infrared electromagnetic radiation.
  • the collimating reflective optical element is configured to receive infrared electromagnetic radiation emitted by the infrared source, to collimate or substantially collimate the received infrared electromagnetic radiation, and to direct the collimated or substantially collimated infrared electromagnetic radiation along an optical path that passes through the flow path formed by the chamber.
  • the diffractive reflective optical element configured to receive collimated or substantially collimated infrared electromagnetic radiation along the optical path, and to diffract the received collimated or substantially collimated infrared electromagnetic radiation.
  • the photosensitive detector is configured to receive diffracted infrared electromagnetic radiation that has passed through the flow path formed by the chamber from the diffractive reflective optical element, and to generate output signals that convey information related to one or more parameters of the received infrared electromagnetic radiation.
  • Another aspect of the invention relates to a method of analyzing gas within an gas measurement module configured to be inserted into a ventilation circuit that is in fluid communication with an airway of a subject.
  • the method comprises generating infrared electromagnetic radiation; reflectively collimating or substantially collimating the generated infrared electromagnetic radiation; directing the collimated or substantially collimated infrared electromagnetic radiation along an optical path that passes through a flow path formed by the gas measurement module within which gas from the airway of the subject flows; reflectively diffracting the collimated or substantially collimated infrared electromagnetic radiation; and generating output signals that convey information related to one or more parameters of the infrared electromagnetic radiation that has been diffracted and has passed through the flow path.
  • Yet another aspect of the invention relates to a system configured to analyze gas, the system configured to be inserted into a ventilation circuit that is in fluid communication with an airway of a subject.
  • the system comprises means for generating infrared electromagnetic radiation; means for reflectively collimating or substantially collimating the generated infrared electromagnetic radiation; means for directing the collimated or substantially collimated infrared electromagnetic radiation along an optical path that passes through a flow path formed by the system within which gas from the airway of the subject flows; means for reflectively diffracting the collimated or substantially collimated infrared electromagnetic radiation; and means for generating output signals that convey information related to one or more parameters of the infrared electromagnetic radiation that has been diffracted and has passed through the flow path.
  • FIG. 1 illustrates a system configured to analyze the composition of gas within a
  • FIG. 2 illustrates components of a spectrometer included in an gas measurement module, in accordance with one or more embodiments of the invention.
  • FIG. 3 illustrates components of a spectrometer included in an gas measurement module, in accordance with one or more embodiments of the invention.
  • FIG. 4 illustrates components of a spectrometer included in an gas measurement module, in accordance with one or more embodiments of the invention
  • FIG. 5 illustrates components of a spectrometer included in an gas measurement module, in accordance with one or more embodiments of the invention.
  • FIG. 1 illustrates a system 10 configured to analyze the composition of gas within a ventilation circuit 12 from which a subject 14 may receive ventilation therapy.
  • the ventilation circuit 12 is connected at one end to a pressure generator configured to generate a pressurized flow of breathable gas for delivery to the airway of subject 14 through ventilation circuit 12.
  • system 10 includes an gas measurement module 16.
  • the ventilation circuit 12 includes a circuit conduit 18 and a subject interface appliance 20.
  • an airway of subject 14 is engaged to place ventilation circuit 12 in fluid communication with the airway of subject 14.
  • the airway of subject 14 is engaged, and placed in fluid communication with ventilation circuit 12, by subject interface appliance 20.
  • the subject interface appliance 20 may engage one or more orifices of the airway of subject 14 in a sealed or unsealed manner.
  • subject interface appliance 20 may include, for example, an endotracheal tube, a nasal cannula, a tracheotomy tube, a nasal mask, a nasal/oral mask, a full face mask, a total face mask, a partial rebreathing mask, or other interface appliances that communicate a flow of gas with an airway of a subject.
  • the present invention is not limited to these examples, and contemplates implementation of any subject interface.
  • the circuit conduit 18 is configured to convey gas toward and away from subject
  • circuit conduit 18 may include a flexible conduit.
  • circuit conduit 18 is not necessarily limited to a tubular member that conveys pressurized gas flows to and/or from subject interface appliance 20.
  • the circuit conduit 18 may include any hollow body, container, and/or chamber placed in fluid communication with the airway of subject 14 by subject interface appliance 20.
  • the circuit conduit 18 referred to herein may be formed as a chamber located on the actual subject interface appliance 20. This chamber may be in fluid communication with a gas source, and/or with ambient atmosphere.
  • the gas measurement module 16 is configured to analyze the composition of gas within ventilation circuit 12. As such, gas measurement module 16 is configured to be placed in communication with circuit conduit 18. This may include insertion of gas measurement module 16 into circuit conduit 18. This insertion may be selectively removable, and/or substantially permanent.
  • ventilation circuit 12 includes a dock in circuit conduit 18 configured to removably receive gas measurement module 16 therein.
  • the gas measurement module 16 forms a chamber therein having a first opening 22 and a second opening 24 disposed on gas measurement module 16 such that if gas measurement module 16 is inserted into circuit conduit 18, gas is transported to and/or from the airway of subject 14 through a flow path between first opening 22 and second opening 24 formed by the chamber.
  • the chamber is formed as a sidestream chamber (rather than a mainstream chamber). In these implementations, gas passing through gas
  • measurement module 16 between first opening and second opening 24 is drawn off into the sidestream chamber for analysis.
  • the gas measurement module 16 carries optical and/or electronic components that facilitate analysis of the composition of the gas within the chamber formed by gas
  • gas measurement module 16 may form, for instance, a diffraction grating spectrometer.
  • optical and/or electronic components of gas measurement module 16 that facilitate composition analysis are configured to minimize the form factor of gas
  • gas measurement module 16 For example, if gas measurement module 16 is too bulky and/or awkward, then implementation may be difficult (e.g., susceptible to inadvertent disconnection and/or breakage), uncomfortable for subject 14, and/or have other draw backs.
  • FIG. 2 illustrates an exemplary configuration of components of gas measurement module 16 that enable composition analysis of gas within gas measurement module 16.
  • the chamber formed by gas measurement module 16 is identified as element 26 bounded by walls 28. It will be appreciated that the illustration of chamber 26 as only being formed by walls 28 is to enable the components of gas measurement module 16 that analyze gaseous composition to be viewed more easily. Further, the illustration of chamber 26 as being bounded by flat, parallel walls 28 is also illustrative. For example, chamber 26 may be formed having a round cross-section and/or a cross-section of some other shape.
  • the collimating reflective optical element 32 can be seen positioned to one side of the walls 28 that form chamber 26.
  • the source 30 is configured to emit electromagnetic radiation 34 in the infrared spectrum.
  • the electromagnetic radiation 34 includes electromagnetic radiation in a first wavelength band related to carbon dioxide and nitrous oxide (e.g., between about 3.5 and about 5 microns) and/or a second wavelength band related to one or more anesthetic agents.
  • the optical system formed within gas measurement module 16 includes a slit 36 disposed between source 30 and collimating reflective optical element 32.
  • the optical system images slit 36 as the source of the electromagnetic radiation. This may enhance resolution of the "source" in the system caused by
  • the collimating reflective optical element 32 is configured to collimate electromagnetic radiation 34 to produce a collimated beam of electromagnetic radiation 38 that is directed along an optical path that traverses the flow path formed within chamber 26.
  • collimating reflective optical element 32 is formed such that source 30 can be disposed off of the optical axis of electromagnetic radiation 38, and even off of the optical path of electromagnetic radiation 38. This provides enhancements in form factor over conventional source/reflector configurations in which the source is in the optical path (if not on the optical axis) of collimated light reflected from the collimating reflector.
  • the distance between collimating reflective optical element 32 and walls 28 would be increased by the bulk of source 30 and the distance required for the electromagnetic radiation 34 to disperse from source 30 to an appropriate cross-sectional size for beam of electromagnetic radiation 38.
  • This increased distance requirement would be reflected in the overall form factor of gas measurement module 16 and would manifest itself in an increased width of gas measurement module 16.
  • the source 30 positioned out of the optical path of electromagnetic radiation 38 the volume of gas measurement module 16 associated with the bulk of source 30 and the distance required for dispersal of electromagnetic radiation 34 can be positioned to run with the length and/or the height of gas measurement module 16, and not significantly impact the width of gas measurement module 16.
  • the collimating reflective optical element 32 may provide enhancements over systems that require refractive elements for collimation.
  • gas measurement module 16ln the wavelength range(s)s to be processed by collimating reflective optical element 32 (e.g., infrared), materials for refractive optical elements are somewhat limited (e.g., silicon, salts). These materials tend to be expensive and hard to work with. Particularly on the size scale to be used in gas measurement module 16. Further, these refractive materials tend to take up a relatively large amount of space.
  • refractive optical elements may provide for a larger field of view than collimating reflective optical element 32.
  • FIG. 3 illustrates a ray-tracing that shows the manner in which electromagnetic
  • collimating reflective optical element 32 has a reflective surface that is asymmetric and aspherical.
  • the reflective surface may be a parabolic shaped reflector formed from an off-axis parabolic section.
  • FIG. 3 further shows how source 30 is disposed off of the optical path of electromagnetic radiation 38. Because of the positioning of source 30 to reduce the width of gas measurement module 16, as was discussed above, a central ray 40 of electromagnetic radiation 34 becomes incident on collimating reflective optical element 32 along a path that has an acute angle with respect to the plane of walls 28 where electromagnetic radiation 38 enters chamber 26. In an embodiment in which walls 28 are rounded, this plane would be the plane tangential to wall 28 where central ray 40 enters chamber 26. For example, this angle ⁇ 9may be less than 45 degrees
  • collimating reflective optical element 32 is formed from molded plastic , and/or other materials.
  • the reflective surface of collimating reflective optical element 32 may be formed by gold, aluminum, and/or other reflective materials, and/or other coatings and/or materials.
  • walls 28 include a pair of optically transmissive windows 42.
  • the windows 42 may be formed, for example, from silicon, germanium, sapphire, and/or other materials.
  • FIG. 4 shows a view of the components of gas measurement module 16 on the
  • a diffractive reflective optical element 44 opposite side of gas measurement chamber 26 from the view shown in FIG. 3. Specifically, in the view shown in FIG. 4, a diffractive reflective optical element 44, a focusing reflective optical element 46, and a photosensitive detector 48 are shown.
  • the diffractive reflective optical element 44 is configured to diffract electromagnetic radiation 38 after electromagnetic radiation 38 has traversed chamber 26. At least a portion of electromagnetic radiation 38 diffracted by diffractive reflective optical element 44 forms a beam of diffracted electromagnetic radiation 50 that becomes incident on focusing reflective optical element 46. The diffraction of electromagnetic radiation at diffractive reflective optical element 44 is effective by diffractive elements formed on the reflective surface of diffractive reflective optical element 44.
  • the diffractive elements may include grating lines. The grating lines may be spaced at about 20 microns, and/or at other wavelength-related spacings.
  • diffractive reflective optical element 44 oscillated about an axis of rotation.
  • the axis of rotation is parallel to the diffraction gratings and ideally is in the plane of the gratings.
  • diffractive reflective optical element 44 is formed from replicated or molded plastic, and/or other materials, with a gold, aluminum, or other reflective material coating providing the reflective surface.
  • slit 36 may be arranged between
  • the slit 36 may be oriented in a direction that is substantially parallel to the diffraction gratings formed on diffractive reflective optical element 44 when electromagnetic radiation from slit 36 is projected by gas measurement module 16reflector 32 onto diffractive reflective optical element 44.
  • focusing reflective optical element 46 is formed from replicated or molded plastice, and/or other materials, with a gold, aluminum, or other reflective material coating providing the reflective surface.
  • the photosensitive detector 48 is configured to receive the electromagnetic radiation 50 focused by focusing reflective optical element 46, and to generate output signals that convey information related to one or more parameters of the received electromagnetic radiation 50.
  • the one or more parameters may include, for example, intensity as a function of wavelength, and/or other parameters.
  • a slit (not shown) may be disposed at
  • photosensitive detector 48 such that the parameter(s) of electromagnetic radiation 50 detected by photosensitive detector 48 provide an indication of the intensity of a specific wavelength range of electromagnetic radiation 38, which is commensurate with the molecular species being monitored, after electromagnetic radiation 38 has passed through chamber 26.
  • composition of the gas within chamber 26 detection of intensities of specific wavelengths of electromagnetic radiation 38 after electromagnetic radiation 38 has passed through chamber 26 will enable determinations of the composition of gas within chamber 26.
  • a processor configured to receive the output signals generated by photosensitive detector 48.
  • the processor may be provided with information related to the scanning position and/or frequency of diffractive reflective optical element 44 at a given point in time.
  • FIG. 5 illustrates a view of gas measurement module 16 that shows a scanner module 52 and a detector module 54.
  • the scanner module 52 is configured to oscillate diffractive reflective optical element 44 about its axis of rotation. This oscillation may have a
  • scanner module 52 One or more exemplary embodiments of scanner module 52 are described, for example in U.S. Patent No. 7,605,370, entitled
  • the detector module 54 may be configured to detect a plurality of spectral bands of within electromagnetic radiation 50.
  • detector module 54 may include one or more beam splitters that divide electromagnetic radiation into a plurality of separate beams, and a plurality of photosensitive detectors configured to receive different spectral bands as diffractive reflective optical element 44 is oscillated over its range.
  • beam splitters that divide electromagnetic radiation into a plurality of separate beams
  • photosensitive detectors configured to receive different spectral bands as diffractive reflective optical element 44 is oscillated over its range.
  • several such configurations of collimating element, diffraction elements, beam splitter(s), focusing element(s), and photosensitive detectors are described in the '370 Patent. It will be appreciated that the particular configuration of the optical elements in this disclosure, and in the '370 Patent are not intended to be limiting. The scope of this disclosure includes embodiments, by way of non-limiting example, in which diffractive reflective optical element 44 is positioned on the other side of chamber 26. Other potential configurations will also be apparent.
  • diffractive reflective optical element 44, focusing reflective optical element 46, and/or detector module 54 may be arranged such that the optical path of electromagnetic radiation 50 between diffractive reflective optical element 44 and detector module 54 is substantially parallel with wall 28 at the location where electromagnetic radiation 38 passes through. This may enable the optical length required to suitably process electromagnetic radiation 50 between diffractive reflective optical element 44 and detector module 54 to be attained within gas measurement module 16 without adding the entire distance to the width of gas measurement module 16. As was discussed above, this may enhance the usability, comfort, and/or other aspects of gas measurement module 16 in a therapeutic setting.

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Abstract

L'invention porte sur l'analyse d'un gaz à l'intérieur d'un circuit de ventilation au moyen d'un spectromètre compris dans un adaptateur de voie aérienne et inséré dans le circuit de ventilation. Le spectromètre est constitué par des éléments réfléchissants traitant le rayonnement électromagnétique tout en repliant le trajet du rayonnement électromagnétique de manière à améliorer le facteur de forme de l'adaptateur de voie aérienne. En outre, du fait de l'échelle du spectromètre dans l'adaptateur de voie aérienne, les économies de coût associées à la fabrication des éléments réfléchissants au lieu d'éléments réfractants peuvent réduire significativement le coût de l'adaptateur de voie aérienne.
PCT/IB2010/055535 2009-12-09 2010-12-01 Module de mesure de gaz destiné à être utilisé dans des configurations thérapeutiques comprenant un micro-spectromètre à balayage réfléchissant Ceased WO2011070485A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US13/514,476 US9510774B2 (en) 2009-12-09 2010-12-01 Gas measurement module for use in therapeutic settings comprising reflective scanning microspectrometer
EP10798394.2A EP2509494B1 (fr) 2009-12-09 2010-12-01 Module de mesure de gaz destiné à être utilisé dans des configurations thérapeutiques comprenant un micro-spectromètre à balayage réfléchissant
JP2012542659A JP5938350B2 (ja) 2009-12-09 2010-12-01 ガス測定モジュール
CN201080055837.6A CN102651996B (zh) 2009-12-09 2010-12-01 用于在治疗设施中使用的包括反射扫描微型光谱仪的气体测量模块

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26792909P 2009-12-09 2009-12-09
US61/267,929 2009-12-09

Publications (1)

Publication Number Publication Date
WO2011070485A1 true WO2011070485A1 (fr) 2011-06-16

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PCT/IB2010/055535 Ceased WO2011070485A1 (fr) 2009-12-09 2010-12-01 Module de mesure de gaz destiné à être utilisé dans des configurations thérapeutiques comprenant un micro-spectromètre à balayage réfléchissant

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US (1) US9510774B2 (fr)
EP (1) EP2509494B1 (fr)
JP (1) JP5938350B2 (fr)
CN (1) CN102651996B (fr)
WO (1) WO2011070485A1 (fr)

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JP2015505045A (ja) * 2011-12-16 2015-02-16 コーニンクレッカ フィリップス エヌ ヴェ 呼吸性ガスのフローの同じ側に位置する検出器と放射体を用いて呼吸性ガスのフローの組成をモニタリングするシステムと方法
US9201002B2 (en) 2009-12-29 2015-12-01 Koninklijke Philips N.V. Gas measurement module for use in therapeutic settings having a microspectrometer with a shortened optical path
GB2572138A (en) * 2018-03-15 2019-09-25 Cambridge Respiratory Innovations Ltd Improved capnometer

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WO2013093746A1 (fr) * 2011-12-19 2013-06-27 Koninklijke Philips Electronics N.V. Système et procédé d'émission de rayonnement infrarouge utilisant un rayonnement réfléchi pour améliorer un rendement d'émission
US10281140B2 (en) 2014-07-15 2019-05-07 Chevron U.S.A. Inc. Low NOx combustion method and apparatus
US20170184492A1 (en) * 2015-12-27 2017-06-29 Comdek Industrial Corporation Gas analyzer system
US11692934B2 (en) * 2020-07-23 2023-07-04 Masimo Corporation Solid-state spectrometer

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JP2013513793A (ja) 2013-04-22
US20120242980A1 (en) 2012-09-27
CN102651996B (zh) 2016-02-17
EP2509494A1 (fr) 2012-10-17
JP5938350B2 (ja) 2016-06-22
US9510774B2 (en) 2016-12-06
CN102651996A (zh) 2012-08-29

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