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WO2010119365A3 - A medicinal cream made using clotrimazole and chitosan and a process to make the same - Google Patents

A medicinal cream made using clotrimazole and chitosan and a process to make the same Download PDF

Info

Publication number
WO2010119365A3
WO2010119365A3 PCT/IB2010/051461 IB2010051461W WO2010119365A3 WO 2010119365 A3 WO2010119365 A3 WO 2010119365A3 IB 2010051461 W IB2010051461 W IB 2010051461W WO 2010119365 A3 WO2010119365 A3 WO 2010119365A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
clotrimazole
skin
chitosan
treating fungal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2010/051461
Other languages
French (fr)
Other versions
WO2010119365A2 (en
Inventor
Sulur Subramaniam Vanangamudi
Madhavan Srinivasan
Neelakandan Narayanan Chulliel
Kausik Ghosh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP10717775A priority Critical patent/EP2419084A2/en
Publication of WO2010119365A2 publication Critical patent/WO2010119365A2/en
Anticipated expiration legal-status Critical
Publication of WO2010119365A3 publication Critical patent/WO2010119365A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention is directed to a composition for treating fungal skin infections, along with skin rejuvenation. More particularly, the present invention relates to a pharmaceutical cream comprising a biopolymer, and an antifungal active ingredient. It discloses a composition for treating fungal skin infections along with skin rejuvenation containing a) a biopolymer in the form of chitosan, b) an active pharmaceutical ingredient (API) composition in the form of clotrimazole used in treating fungal skin infections, c) a cream base containing primary and secondary emulsifiers, waxy materials, co -solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants and d) water. The active ingredients, namely chitosan, and an anti fungal agent in the form of clotrimazole, are incorporated in cream base for use in treating fungal skin infections with allergy & itching, & wounds on human skin involving contacting human skin with the above identified composition.
PCT/IB2010/051461 2009-04-13 2010-04-05 A medicinal cream made using clotrimazole and chitosan and a process to make the same Ceased WO2010119365A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP10717775A EP2419084A2 (en) 2009-04-13 2010-04-05 A medicinal cream made using clotrimazole and chitosan and a process to make the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN949/MUM/2009 2009-04-13
IN949MU2009 2009-04-13

Publications (2)

Publication Number Publication Date
WO2010119365A2 WO2010119365A2 (en) 2010-10-21
WO2010119365A3 true WO2010119365A3 (en) 2011-10-27

Family

ID=42272147

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2010/051461 Ceased WO2010119365A2 (en) 2009-04-13 2010-04-05 A medicinal cream made using clotrimazole and chitosan and a process to make the same

Country Status (2)

Country Link
EP (1) EP2419084A2 (en)
WO (1) WO2010119365A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005087195A2 (en) * 2004-03-18 2005-09-22 Panacea Biotec Ltd. Novel compositions for topical delivery
WO2010109434A2 (en) * 2009-03-25 2010-09-30 Sulur Subramaniam Vanangamudi A medicinal antibacterial, antifungal and steroids cream and a process to make it

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005087195A2 (en) * 2004-03-18 2005-09-22 Panacea Biotec Ltd. Novel compositions for topical delivery
WO2010109434A2 (en) * 2009-03-25 2010-09-30 Sulur Subramaniam Vanangamudi A medicinal antibacterial, antifungal and steroids cream and a process to make it

Also Published As

Publication number Publication date
EP2419084A2 (en) 2012-02-22
WO2010119365A2 (en) 2010-10-21

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